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Results for "

heme oxygenase 1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Autophagy (2) Bacterial (2) Endogenous Metabolite (4) Ferroptosis (1) IFNAR (2) Influenza Virus (1) Isotope-Labeled Compounds (2) Keap1-Nrf2 (7) NO Synthase (3) Prostaglandin Receptor (3) Reactive Oxygen Species (17) Ribosomal S6 Kinase (RSK) (2) STAT (2) TNF Receptor (2)
By Research Areas:	Cancer (14) Cardiovascular Disease (3) Infection (5) Inflammation/Immunology (10) Metabolic Disease (2) Neurological Disease (7)

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111798

Heme Oxygenase-1-IN-1 5 Publications Verification	Reactive Oxygen Species	Cancer
Heme Oxygenase-1-IN-1 (compound 2) is a potent heme oxygenase 1 (HO-1) inhibitor, with an IC₅₀ of 0.25 μM. Heme Oxygenase-1-IN-1 can be used for cancer research .

HY-111798A

Heme Oxygenase-1-IN-1 hydrochloride 5 Publications Verification	Reactive Oxygen Species	Cancer
Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 (HO-1) inhibitor with an IC₅₀ of 0.25 μM .

HY-B2184

Sofalcone 1 Publications Verification	Autophagy Bacterial	Infection Inflammation/Immunology
Sofalcone, a gastric antiulcer agent, is known to induce the expression of **Heme oxygenase-1 (HO-1**) in gastric epithelium.

HY-118487

OB-24 1 Publications Verification	Others	Cancer
OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA) .

HY-153020

HIF-PHD-IN-3	Reactive Oxygen Species	Cardiovascular Disease
HIF-PHD-IN-3 (compound 4) is a potent hiPSC-CM cardioprotective scaffold. HIF-PHD-IN-3 can induce upregulation of **heme oxygenase-1** .

HY-101194

Tin protoporphyrin IX dichloride 15+ Cited Publications Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX	Reactive Oxygen Species	Cancer
Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model .

HY-115713

Heme Oxygenase-1-IN-2	Reactive Oxygen Species	Cancer
Heme Oxygenase-1-IN-2 is a novel **heme oxygenase-1 inhibitor (IC₅₀** = 0.95 μM) with potent in vitro antiproliferative activity.

HY-162857

Heme Oxygenase-1-IN-3	Others	Neurological Disease Cancer
Heme Oxygenase-1-IN-3 (compound 4) is a highly selective heme oxygenase-1 (HO-1) inhibitor (K_d=141 nM) that can be used in the research of cancer and neurodegenerative diseases .

HY-B2184S

Sofalcone-d4	Isotope-Labeled Compounds	Infection Inflammation/Immunology
Sofalcone-d₄ is deuterated labeled Sofalcone. Sofalcone, a gastric antiulcer agent, is known to induce the expression of **Heme oxygenase-1 (HO-1**) in gastric epithelium.

HY-B2184R

Sofalcone (Standard)	Autophagy Bacterial	Infection Inflammation/Immunology
Sofalcone (Standard) is the analytical standard of Sofalcone. This product is intended for research and analytical applications. Sofalcone, a gastric antiulcer agent, is known to induce the expression of **Heme oxygenase-1 (HO-1**) in gastric epithelium.

HY-134608

Cobalt protoporphyrin IX Co-PPIX	Reactive Oxygen Species Influenza Virus	Infection
Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .

HY-161601

Ferroptosis inducer-2	Ferroptosis Reactive Oxygen Species	Cancer
Ferroptosis inducer-2 (Compound 24) is an inducer for heme oxygenase-1 (HO-1). Ferroptosis inducer-2 exhibits anticancer activity against triple-negative breast cancer (TNBC) cells through induction of ferroptosis .

HY-124815

CP-312	Reactive Oxygen Species	Others
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress .

HY-N0061

Ethyl ferulate 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-N0761A

trans-Isoferulic acid trans-3-Hydroxy-4-methoxycinnamic acid	NO Synthase Prostaglandin Receptor	Inflammation/Immunology
trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .

HY-N2535

Coniferaldehyde 1 Publications Verification 4-Hydroxy-3-methoxycinnamaldehyde	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N6953

Garcinone D 2 Publications Verification	STAT Keap1-Nrf2 Reactive Oxygen Species	Neurological Disease
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners .

HY-101193

Zinc Protoporphyrin Maximum Cited Publications 39 Publications Verification Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Reactive Oxygen Species Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-N0761AS

trans-Isoferulic acid-d3	Prostaglandin Receptor NO Synthase	Inflammation/Immunology
trans-Isoferulic acid-d₃ is the deuterium labeled trans-Isoferulic acid[1]. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[2].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[3].

HY-N0761AR

trans-Isoferulic acid (Standard)	NO Synthase Prostaglandin Receptor	Inflammation/Immunology
trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .

HY-N2535R

Coniferaldehyde (Standard)	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Coniferaldehyde (Standard) is the analytical standard of Coniferaldehyde. This product is intended for research and analytical applications. Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N6953R

Garcinone D (Standard)	STAT Keap1-Nrf2 Reactive Oxygen Species	Neurological Disease
Garcinone D (Standard) is the analytical standard of Garcinone D. This product is intended for research and analytical applications. Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration-and time-dependent manners .

HY-101193S

Zinc Protoporphyrin-d2,15N2 Zn(II)-protoporphyrin IX-d2,15N2; ZnPP-d2,15N2; Zinc Protoporphyrin-9-d2,15N2	Apoptosis Endogenous Metabolite Reactive Oxygen Species Isotope-Labeled Compounds	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin-d₂, ¹⁵N₂ is ¹⁵N and deuterated labeled Zinc Protoporphyrin (HY-101193). Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-106359

Delmitide RDP-58	TNF Receptor IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Delmitide (RDP58) is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide can be used for the research of ulcerative colitis .

HY-106359A

Delmitide acetate RDP-58 acetate	TNF Receptor IFNAR Reactive Oxygen Species	Cancer
Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide acetate inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide acetate can be used for the research of ulcerative colitis .

HY-N0643

Carnosol 10+ Cited Publications	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

HY-N0643R

Carnosol (Standard)	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite	Cancer
Carnosol (Standard) is the analytical standard of Carnosol. This product is intended for research and analytical applications. Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

HY-120251A

Leteprinim potassium AIT-082	Reactive Oxygen Species	Neurological Disease
Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases *heme-oxygenase* 1 and 2 mRNA levels that play role in cellular defense against *reactive oxygen* species** .

HY-120251

Leteprinim AIT-082 free acid	Reactive Oxygen Species	Neurological Disease
Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases *heme-oxygenase* 1 and 2 mRNA levels that play role in cellular defense against *reactive oxygen* species** .

HY-118487A

OB-24 free base	Others	Cancer
OB-24 free base is a compound that potently and selectively inhibits heme oxygenase 1 (HO-1) and has the potential to inhibit advanced prostate cancer. OB-24 significantly reduces protein carbonylation and the formation of reactive oxygen species by selectively inhibiting HO-1 activity in prostate cancer cells. OB-24 significantly inhibited cell proliferation in vitro and inhibited tumor growth and lymph node and lung metastasis in vivo. OB-24 exhibits powerful synergy when used in combination with Taxol .

HY-147517

Keap1-Nrf2-IN-9	Keap1-Nrf2	Neurological Disease Inflammation/Immunology
Keap1-Nrf2-IN-9 (compound 11) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with an IC₅₀ of 0.575 µM. Keap1-Nrf2-IN-9 increases the expression of Nrf2 target genes including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Keap1-Nrf2-IN-9 shows not cytotoxic activity in ARPE19 cells .

Cat. No.	Product Name	Target	Research Area

HY-106359A

Delmitide acetate RDP-58 acetate	TNF Receptor IFNAR Reactive Oxygen Species	Cancer
Delmitide (RDP58) acetate is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide acetate inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide acetate can be used for the research of ulcerative colitis .

HY-106359

Delmitide RDP-58	TNF Receptor IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Delmitide (RDP58) is an orally active d-isomer decapeptide with potent anti-inflammatory activity. Delmitide inhibits production of TNF-α, IFN-γ, and interleukin (IL)-12, and up-regulates heme oxygenase 1 activity. Delmitide can be used for the research of ulcerative colitis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0061

Ethyl ferulate 1 Publications Verification	Structural Classification Monophenols Simple Phenylpropanols Source classification Phenols Dicerothamnus rhinocerotis Phenylpropanoids Umbelliferae Plants	Reactive Oxygen Species
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-N0761A

trans-Isoferulic acid trans-3-Hydroxy-4-methoxycinnamic acid	Ketones, Aldehydes, Acids Source classification Ranunculaceae Plants	NO Synthase Prostaglandin Receptor
trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .

HY-N2535

Coniferaldehyde 1 Publications Verification 4-Hydroxy-3-methoxycinnamaldehyde	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Keap1-Nrf2 Apoptosis
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N6953

Garcinone D 2 Publications Verification	Structural Classification Xanthones Guttiferae Source classification Phenols Polyphenols Garcinia mangostana Linn. Plants	STAT Keap1-Nrf2 Reactive Oxygen Species
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners .

HY-101193

Zinc Protoporphyrin Maximum Cited Publications 39 Publications Verification Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-N0643

Carnosol 10+ Cited Publications	Structural Classification Classification of Application Fields Paramacrolobium coeruleum (Taub.) J.Léonard Food Preservation Research Source classification Plants Agricultural Research Terpenoids Labiatae Phenols Polyphenols Diterpenoids Disease Research Fields Cancer	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

HY-N0761AR

trans-Isoferulic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Ranunculaceae Source classification Plants	NO Synthase Prostaglandin Receptor
trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .

HY-N2535R

Coniferaldehyde (Standard)	Structural Classification Monophenols other families Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants	Keap1-Nrf2 Apoptosis
Coniferaldehyde (Standard) is the analytical standard of Coniferaldehyde. This product is intended for research and analytical applications. Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N6953R

Garcinone D (Standard)	Structural Classification Xanthones Guttiferae Source classification Phenols Polyphenols Garcinia mangostana Linn. Plants	STAT Keap1-Nrf2 Reactive Oxygen Species
Garcinone D (Standard) is the analytical standard of Garcinone D. This product is intended for research and analytical applications. Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration-and time-dependent manners .

HY-N0643R

Carnosol (Standard)	Structural Classification Paramacrolobium coeruleum (Taub.) J.Léonard Terpenoids Labiatae Source classification Phenols Polyphenols Diterpenoids Plants	Ribosomal S6 Kinase (RSK) Keap1-Nrf2 Endogenous Metabolite
Carnosol (Standard) is the analytical standard of Carnosol. This product is intended for research and analytical applications. Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC₅₀ of ~5.5 μM . Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) .

Species:	Human (1) Mouse (1)
Tag:	His (1) Tag Free (1)
Source:	P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70276

	HO-1 Protein, Human 1 Publications Verification rHuheme oxygenase 1/HO-1; heme oxygenase 1; HO-1; HMOX1; HO; HO1	Human	E. coli
	HO-1 Protein, an enzyme, plays a critical role in cellular defense against oxidative stress and inflammation. Dysregulation of HO-1 Protein has been implicated in several diseases, including cardiovascular disorders and neuroinflammatory conditions. Targeting HO-1 Protein may offer potential therapeutic interventions by enhancing antioxidant defenses, reducing inflammation, and potentially treating these diseases. HO-1 Protein, Human is the recombinant human-derived HO-1 protein, expressed by E. coli , with tag free. The total length of HO-1 Protein, Human is 261 a.a., with molecular weight of ~30.0 kDa.

HY-P700495

	HO-1 Protein, Mouse (His) rHuheme oxygenase 1/HO-1; heme oxygenase 1; HO-1; HMOX1; HO; HO1	Mouse	P. pastoris
	HO-1 Protein catalyzes the oxidative cleavage of heme, releasing carbon monoxide (CO) and ferrous iron. It provides protection against programmed cell death by catabolizing free heme, preventing apoptosis sensitization. HO-1 Protein, Mouse (His) is the recombinant mouse-derived HO-1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of HO-1 Protein, Mouse (His) is 289 a.a., with molecular weight of ~35 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-B2184S

Sofalcone-d4
Sofalcone-d₄ is deuterated labeled Sofalcone. Sofalcone, a gastric antiulcer agent, is known to induce the expression of **Heme oxygenase-1 (HO-1**) in gastric epithelium.

HY-N0761AS

trans-Isoferulic acid-d3

trans-Isoferulic acid-d₃ is the deuterium labeled trans-Isoferulic acid[1]. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[2].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[3].

HY-101193S

Zinc Protoporphyrin-d2,15N2

Zinc Protoporphyrin-d₂, ¹⁵N₂ is ¹⁵N and deuterated labeled Zinc Protoporphyrin (HY-101193). Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H₂O₂ . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80499

	Heme Oxygenase 1 Antibody	WB, IHC-P, IP, FC	Human
	Heme Oxygenase 1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 33 kDa, targeting to Heme Oxygenase 1(HO-1). It can be used for WB,IHC-P,IP,FC assays with tag free, in the background of Human.