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nasal

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54

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Peptides

7

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0475
    Xylometazoline hydrochloride

    		Adrenergic Receptor Inflammation/Immunology
    Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .
    Xylometazoline hydrochloride
  • HY-B0556A
    Tetrahydrozoline hydrochloride

    Tetryzoline hydrochloride

    		 Adrenergic Receptor Cardiovascular Disease Endocrinology
    Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
    Tetrahydrozoline hydrochloride
  • HY-B0556
    Tetrahydrozoline

    Tetryzoline

    		 Adrenergic Receptor Cardiovascular Disease
    Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
    Tetrahydrozoline
  • HY-B0475A
    Xylometazoline

    		Adrenergic Receptor Inflammation/Immunology
    Xylometazoline is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .
    Xylometazoline
  • HY-B0475S
    Xylometazoline-d4 hydrochloride

    		Adrenergic Receptor Isotope-Labeled Compounds Inflammation/Immunology
    Xylometazoline-d4 hydrochloride is deuterated labeled Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .
    Xylometazoline-d4 hydrochloride
  • HY-B0556B
    Tetrahydrozoline nitrate

    Tetryzoline nitrate

    		 Adrenergic Receptor Cardiovascular Disease Metabolic Disease
    Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
    Tetrahydrozoline nitrate
  • HY-W720736
    Tinazoline

    		Others Cardiovascular Disease
    Tinazoline, imidazole derivative, is a vasoconstrictor. Tinazoline can as nasal decongestant for the research of common cold .
    Tinazoline
  • HY-158194
    α2C adrenoceptor agonist 1

    		Adrenergic Receptor Cancer
    α2C adrenoceptor agonist 1 (Compound A) is an orally active, highly selective, and non-central nervous system penetrating agonist for the α2C-adrenoceptor, with EC50 and Ki values of 108 nM and 12 nM, respectively. α2C adrenoceptor agonist 1 can be used in the study of nasal congestion .
    α2C adrenoceptor agonist 1
  • HY-106368
    Dexamethasone cipecilate

    NS-126

    		 Others Inflammation/Immunology
    Dexamethasone cipecilate (NS-126) is a corticosteroid whose local efficacy and durability have been enhanced by the introduction of a lipophilic functional group. Dexamethasone cipecilate can be used as a nasal spray and is applicable in rhinitis research .
    Dexamethasone cipecilate
  • HY-B0556R
    Tetrahydrozoline (Standard)

    		Adrenergic Receptor Cardiovascular Disease
    Tetrahydrozoline (Standard) is the analytical standard of Tetrahydrozoline. This product is intended for research and analytical applications. Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
    Tetrahydrozoline (Standard)
  • HY-B0556AR
    Tetrahydrozoline hydrochloride (Standard)

    		Adrenergic Receptor Cardiovascular Disease Endocrinology
    Tetrahydrozoline (hydrochloride) (Standard) is the analytical standard of Tetrahydrozoline (hydrochloride). This product is intended for research and analytical applications. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
    Tetrahydrozoline hydrochloride (Standard)
  • HY-N11630
    Pinellic acid

    		Influenza Virus Others
    Pinellic acid is a natural product that could be isolated from a medicinal plant Pinelliae tuber. Pinellic acid is an effective oral adjuvant for nasal influenza vaccine .
    Pinellic acid
  • HY-W042337
    3-Methyl-4-nitrophenol

    		Apoptosis Others
    3-Methyl-4-nitrophenol, an environmental contaminant, is a well-known constituent of diesel exhaust particles and degradation products of insecticide fenitrothion. 3-Methyl-4-nitrophenol can induce nasal epithelial cell apoptosis and increase the permeability of the nasal epithelial barrier. 3-Methyl-4-nitrophenol is also toxic to the female reproductive system.
    3-Methyl-4-nitrophenol
  • HY-B1317
    Thonzylamine

    Neohetramine

    		 Histamine Receptor Inflammation/Immunology
    Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
    Thonzylamine
  • HY-B1317A
    Thonzylamine hydrochloride

    Neohetramine hydrochloride

    		 Histamine Receptor Inflammation/Immunology
    Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
    Thonzylamine hydrochloride
  • HY-B1317R
    Thonzylamine (Standard)

    		Histamine Receptor Inflammation/Immunology
    Thonzylamine (Standard) is the analytical standard of Thonzylamine. This product is intended for research and analytical applications. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
    Thonzylamine (Standard)
  • HY-W650803
    Nemazoline

    A-57219

    		 Adrenergic Receptor Cardiovascular Disease
    Nemazoline (A-57219) is selective α-adrenergic agent with α1-agonist/α2-antagonist activity, which is used as a nasal decongestant. Nemazoline produces decongestion by α1-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of α2-antagonism. Nemazoline also blocks endogenous noradrenaline-mediated α 2-constriction of the resistance vessels .
    Nemazoline
  • HY-11044
    PF-03654746 Tosylate

    		Histamine Receptor Neurological Disease Inflammation/Immunology Endocrinology
    PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms . PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) .
    PF-03654746 Tosylate
  • HY-125918
    Bleomycin A5 hydrochloride

    Pingyangmycin hydrochloride

    		 Apoptosis Antibiotic Infection Cancer
    Bleomycin A5 (Pingyangmycin) hydrochloride is an anti-neoplastic glycoprotein antibiotic. Bleomycin A5 suppresses Drp1-mediated mitochondrial fission and induces apoptosis in human nasal polyp-derived fibroblasts. Bleomycin A5 hydrochloride has anticancer activities relying on its ability to produce RNA and DNA breaks, thus, leading to cell death ..
    Bleomycin A5 hydrochloride
  • HY-W011518
    2′-Deoxy-2′-fluoroguanosine

    		Influenza Virus Infection
    2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation .
    2′-Deoxy-2′-fluoroguanosine
  • HY-B0167A
    Sodium Salicylate
    Maximum Cited Publications
    9 Publications Verification

    Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt

    		 COX NF-κB Ribosomal S6 Kinase (RSK) Autophagy Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation . Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle .
    Sodium Salicylate
  • HY-B0167AR
    Sodium Salicylate (Standard)

    		COX NF-κB Ribosomal S6 Kinase (RSK) Autophagy Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Sodium Salicylate (Standard) is the analytical standard of Sodium Salicylate. This product is intended for research and analytical applications. Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation . Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle .
    Sodium Salicylate (Standard)
  • HY-109134A
    Pizuglanstat hydrate

    TAS-205

    		 Prostaglandin Receptor Inflammation/Immunology
    Pizuglanstat hydrate (TAS-205) is a hematopoietic prostaglandin D synthase (HPGDS) inhibitor. TAS-205 selectively inhibits the synthesis of prostaglandin D2 (PGD2) in cell-based enzymatic tests and in vivo models, and effectively reduces the entry of eosinophils into the nasal cavity and late-stage nasal congestion. When used in combination with montelukast (HY-13315A), TAS-205 showed a significant synergistic inhibitory effect; when used in combination with fexofenadine (HY-B0801A), it also had a certain inhibitory effect on early and late nasal congestion.
    Pizuglanstat hydrate
  • HY-B0475R
    Xylometazoline hydrochloride (Standard)

    		Adrenergic Receptor Inflammation/Immunology
    Xylometazoline (hydrochloride) (Standard) is the analytical standard of Xylometazoline (hydrochloride). This product is intended for research and analytical applications. Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .
    Xylometazoline hydrochloride (Standard)
  • HY-B1067
    Antazoline hydrochloride

    Phenazoline hydrochloride

    		 Histamine Receptor Neurological Disease Endocrinology
    Antazoline (Phenazoline) hydrochloride is a first-generation antihistamine that also has anticholinergic properties and is used to relieve nasal congestion and is also used as eye drops.
    Antazoline hydrochloride
  • HY-161099
    Epifadin

    		Bacterial Infection
    Epifadin is an antimicrobial agent consisting of a non-ribosomally synthesized peptide, a polyketide component and a terminal modified amino acid moiety. Epifadin eliminates nasal Staphylococcus aureus .
    Epifadin
  • HY-19043
    RS-93522

    RS-93522-004

    		 Others Others
    RS-93522 (RS-93522-004) is a compound with calcium channel antagonist activity that is rapidly absorbed and has high bioavailability via nasal administration.
    RS-93522
  • HY-W337897
    Tetradecyl-β-D-maltoside

    		Biochemical Assay Reagents Metabolic Disease
    Tetradecyl-β-D-maltoside is an absorption enhancer which can increase the nasal absorption of regular human insulin or the fast acting insulin analog lyspro-insulin .
    Tetradecyl-β-D-maltoside
  • HY-B1289
    Cetylpyridinium chloride monohydrate
    2 Publications Verification

    Hexadecylpyridinium chloride monohydrate

    		 Bacterial Infection
    Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, and throat and nasal sprays as an antiseptic that kills bacteria and other microorganisms. Effectively prevents plaque and reduces gingivitis.
    Cetylpyridinium chloride monohydrate
  • HY-147299
    Povafonidine

    PGE-6201204

    		 Adrenergic Receptor Cardiovascular Disease
    Povafonidine (PGE-6201204) is a potent α2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion. Povafonidine can be used for nasal congestion research .
    Povafonidine
  • HY-100518A
    T 26c sodium

    		MMP Inflammation/Immunology
    T26c sodium is a potent and selective MMP13 inhibitor with IC50 value of 6.9 pM. T26c sodium can inhibit the degradation of bovine nasal septal cartilage explants .
    T 26c sodium
  • HY-B1067R
    Antazoline hydrochloride (Standard)

    		Histamine Receptor Neurological Disease Endocrinology
    Antazoline (hydrochloride) (Standard) is the analytical standard of Antazoline (hydrochloride). This product is intended for research and analytical applications. Antazoline (Phenazoline) hydrochloride is a first-generation antihistamine that also has anticholinergic properties and is used to relieve nasal congestion and is also used as eye drops.
    Antazoline hydrochloride (Standard)
  • HY-B0556AS
    Tetrahydrozoline-d4 hydrochloride

    Tetryzoline-d4 (hydrochloride)

    		 Adrenergic Receptor Cardiovascular Disease Endocrinology
    Tetrahydrozoline-d4 (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion[1][2].
    Tetrahydrozoline-d4 hydrochloride
  • HY-119123
    Voxvoganan

    LTX-109

    		 Fungal Bacterial Infection
    Voxvoganan (LTX-109), a topical antimicrobial, is highly effective against S. aureus with a MIC range of 2 to 4 μg/mL. Voxvoganan can be used for the research of bacterial skin infections, fungal infections and nasal decolonisation of MRSA .
    Voxvoganan
  • HY-119123A
    Voxvoganan trihydrochloride

    LTX-109 trihydrochloride

    		 Fungal Bacterial Infection
    Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, is highly effective against S. aureus with a MIC range of 2 to 4 μg/mL. Voxvoganan trihydrochloride can be used for the research of bacterial skin infections, fungal infections and nasal decolonisation of MRSA .
    Voxvoganan trihydrochloride
  • HY-B1289R
    Cetylpyridinium chloride monohydrate (Standard)

    		Bacterial Infection
    Cetylpyridinium (chloride monohydrate) (Standard) is the analytical standard of Cetylpyridinium (chloride monohydrate). This product is intended for research and analytical applications. Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, and throat and nasal sprays as an antiseptic that kills bacteria and other microorganisms. Effectively prevents plaque and reduces gingivitis.
    Cetylpyridinium chloride monohydrate (Standard)
  • HY-14818B
    Laninamivir TFA

    R 125489 TFA

    		 Influenza Virus Infection
    Laninamivir TFA (R 125489 TFA) is an antiviral compound with inhibitory and prophylactic activity against influenza A and B viruses. Laninamivir TFA is a long-acting neuraminidase inhibitor administered by nasal inhalation. Laninamivir TFA has shown good safety and efficacy in the inhibition of influenza viruses .
    Laninamivir TFA
  • HY-P4200
    Lugdunin

    		Antibiotic Bacterial Infection
    Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus, and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin .
    Lugdunin
  • HY-11045
    PF-03654746

    		Histamine Receptor Neurological Disease Inflammation/Immunology Endocrinology
    PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 reduces allergen-induced nasal symptoms, might be a novel therapeutic strategy to further explore allergic rhinitis . PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) .
    PF-03654746
  • HY-N7434
    N-Nitrosodiethylamine
    2 Publications Verification

    Diethylnitrosamine; DEN

    		 DNA/RNA Synthesis Cancer
    N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
    N-Nitrosodiethylamine
  • HY-123459
    Garomefrine (hydrochlorid)

    ABT-232; NS-49; PNO-49B

    		 Others Endocrinology
    Garomefrine hydrochlorid (ABT-232) is an α1A-adrenergic agonist with the potential to inhibit urinary incontinence. Garomefrine hydrochlorid showed the greatest contractility in pig nasal mucosal vessels. The biological activity of Garomefrine hydrochlorid has been shown to give it a competitive advantage compared to other drugs. The potency of Garomefrine hydrochlorid makes it a valuable research object in related research .
    Garomefrine (hydrochlorid)
  • HY-B0801A
    Fexofenadine hydrochloride
    4 Publications Verification

    MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride

    		 Histamine Receptor Inflammation/Immunology
    Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine hydrochloride
  • HY-B0801
    Fexofenadine
    4 Publications Verification

    MDL-16455; Terfenadine carboxylate

    		 Histamine Receptor Inflammation/Immunology
    Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine
  • HY-B0801S4
    Fexofenadine-d3-1

    MDL-16455-d3-1; Terfenadine carboxylate-d3-1

    		 Histamine Receptor Isotope-Labeled Compounds Inflammation/Immunology
    Fexofenadine-d3-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .
    Fexofenadine-d3-1
  • HY-105025B
    Thymocartin acetate

    Thymopoietin II (32-35) acetate; TP 4 acetate

    		 Apoptosis Inflammation/Immunology
    Thymocartin (TP 4) acetate is the 32-35 fragment of thymic factor (thymopoietin). Thymocartin acetate inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals. Thymocartin acetate is potential for immunodeficiency diseases research .
    Thymocartin acetate
  • HY-116953
    Lipoxin B4

    LXB4

    		 Endogenous Metabolite Inflammation/Immunology
    Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
    Lipoxin B4
  • HY-N7434S
    N-Nitrosodiethylamine-d4

    Diethylnitrosamine-d4; DEN-d4

    		 DNA/RNA Synthesis Cancer
    N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
    N-Nitrosodiethylamine-d4
  • HY-N7434S1
    N-Nitrosodiethylamine-d10

    Diethylnitrosamine-d10; DEN-d10

    		 DNA/RNA Synthesis Cancer
    N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
    N-Nitrosodiethylamine-d10
  • HY-N2597
    Prunetin

    		Aldehyde Dehydrogenase (ALDH) Inflammation/Immunology
    Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor .
    Prunetin
  • HY-106083
    Quazolast

    RHC 3988

    		 Others Inflammation/Immunology
    Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers .
    Quazolast

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