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synthetic analogue

" in MedChemExpress (MCE) Product Catalog:

54

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2

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2

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21

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2

Isotope-Labeled Compounds

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8495

    Others Metabolic Disease
    4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .
    4'-Hydroxyflavanone
  • HY-B2229

    Bisibuthiamine

    Others Neurological Disease
    Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia.
    Sulbutiamine
  • HY-10001
    Calcipotriol
    20+ Cited Publications

    MC 903; Calcipotriene

    VD/VDR Inflammation/Immunology Cancer
    Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
    Calcipotriol
  • HY-10001A
    Calcipotriol monohydrate
    20+ Cited Publications

    VD/VDR Inflammation/Immunology Cancer
    Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
    Calcipotriol monohydrate
  • HY-15640
    Capsazepine
    Maximum Cited Publications
    34 Publications Verification

    TRP Channel Apoptosis Cancer
    Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, and an antagonist of TRPV1 receptor with an IC50 of 562 nM.
    Capsazepine
  • HY-12309

    AGN 190205; BASF-46928

    Others Neurological Disease
    EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation .
    EC23
  • HY-121241

    Parasite Infection
    Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites .
    Dehydroemetine
  • HY-129801

    Others Others
    N-Ethyl Hexylone hydrochloride is a synthetic Cathinone and analogue of methylone and other beta-keto methylenedioxyamphetamines .
    N-Ethyl Hexylone hydrochloride
  • HY-114671

    CG-4203

    Prostaglandin Receptor Cardiovascular Disease
    Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects .
    Taprostene
  • HY-129757

    Others Prostaglandin Receptor Others
    5-trans-Fluprostenol is a synthetic prostaglandin analogue .
    5-trans-Fluprostenol
  • HY-110337

    Others Others
    FFN 102 mesylate is a synthetic biogenic neurotransmitter analogue with PH-dependent fluorescence and electrical activity .
    FFN 102 mesylate
  • HY-144003

    Biochemical Assay Reagents Inflammation/Immunology
    BAY-R 1005, an immunoenhancing agent, is a synthetic glycolipid analogue (GLA), which is supposed to modulate antibody synthesis .
    BAY-R 1005
  • HY-P2018

    Opioid Receptor Cardiovascular Disease
    FK 33-824, a synthetic analogue of Met-enkephalin, is a selective agonist of the μ-opioid receptor (μ-OR) .
    FK 33-824
  • HY-12506A
    Naspm trihydrochloride
    5+ Cited Publications

    1-Naphthylacetyl spermine trihydrochloride

    iGluR Neurological Disease
    Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
    Naspm trihydrochloride
  • HY-108415

    ICI 80996 sodium salt

    Prostaglandin Receptor Endocrinology
    Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent , and is a PGF2α receptor agonist .
    Cloprostenol sodium salt
  • HY-12506
    Naspm
    5+ Cited Publications

    1-Naphthylacetyl spermine

    iGluR Neurological Disease
    Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
    Naspm
  • HY-P0051

    GnRH Receptor Endocrinology Cancer
    Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .
    Lecirelin
  • HY-10001R

    MC 903 (Standard); Calcipotriene (Standard)

    VD/VDR Inflammation/Immunology Cancer
    Calcipotriol (Standard) is the analytical standard of Calcipotriol. This product is intended for research and analytical applications. Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
    Calcipotriol (Standard)
  • HY-10001AR

    VD/VDR Inflammation/Immunology Cancer
    Calcipotriol (monohydrate) (Standard) is the analytical standard of Calcipotriol (monohydrate). This product is intended for research and analytical applications. Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
    Calcipotriol monohydrate (Standard)
  • HY-116117

    Others Others
    Salicylcurcumin is a synthetic curcumin analogue with antioxidant activity. Salicylcurcumin may affect lipid peroxidation in fish, favoring increased survival, disease resistance, and ultimately growth rate .
    Salicylcurcumin
  • HY-126800

    Others Inflammation/Immunology
    Glycotriosyl glutamine is a synthetic analogue of the Glycopeptide. Glycotriosyl glutamine induces focal glomerulonephritis (FGN) and the appearance of myeloid bodies in the epithelial cells of the podocytes in rats with nephritogenic activity .
    Glycotriosyl glutamine
  • HY-16757
    Trofinetide
    1 Publications Verification

    NNZ-2566

    iGluR Neurological Disease
    Trofinetide (NNZ-2566), a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), has been shown to be neuroprotective in animal models of brain injury.
    Trofinetide
  • HY-A0096S

    Isotope-Labeled Compounds Prostaglandin Receptor Endocrinology
    Iloprost-d4 (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].
    Iloprost-d4
  • HY-12522

    Aur0101; Auristatin-0101

    Microtubule/Tubulin ADC Cytotoxin Cancer
    PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.
    PF-06380101
  • HY-18678A
    Bremelanotide Acetate
    1 Publications Verification

    PT-141 Acetate

    Melanocortin Receptor Endocrinology
    Bremelanotide Acetate (PT-141 Acetate), a synthetic peptide analogue of α-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R for the treatment of sexual dysfunction .
    Bremelanotide Acetate
  • HY-108415R

    ICI 80996 sodium salt (Standard)

    Prostaglandin Receptor Endocrinology
    Cloprostenol sodium salt (Standard) is the analytical standard of Cloprostenol sodium salt. This product is intended for research and analytical applications. Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent , and is a PGF2α receptor agonist .
    Cloprostenol sodium salt (Standard)
  • HY-A0195

    Prostaglandin Receptor Endocrinology
    Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
    Carboprost tromethamine
  • HY-P1714

    FE 203799

    GLP Receptor Metabolic Disease
    Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
    Apraglutide
  • HY-P1714A

    FE 203799 TFA

    GLP Receptor Metabolic Disease
    Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
    Apraglutide TFA
  • HY-P3875

    BM-PACAP

    PACAP Receptor Neurological Disease Metabolic Disease
    [Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect .
    [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
  • HY-15584
    Taltobulin
    3 Publications Verification

    HTI-286; SPA-110

    Microtubule/Tubulin ADC Cytotoxin Apoptosis Cancer
    Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .
    Taltobulin
  • HY-15584A
    Taltobulin trifluoroacetate
    3 Publications Verification

    HTI-286 trifluoroacetate; SPA-110 trifluoroacetate

    Microtubule/Tubulin ADC Cytotoxin Apoptosis Cancer
    Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .
    Taltobulin trifluoroacetate
  • HY-15584B
    Taltobulin hydrochloride
    3 Publications Verification

    HTI-286 hydrochloride; SPA-110 hydrochloride

    Microtubule/Tubulin ADC Cytotoxin Apoptosis Cancer
    Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin hydrochloride inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .
    Taltobulin hydrochloride
  • HY-114570

    NSC 286193; Riboxamide

    Nucleoside Antimetabolite/Analog Orthopoxvirus Infection Cancer
    Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) . Tiazofurin also has anti-orthopoxvirus and anti-variola activities .
    Tiazofurin
  • HY-N8303

    ERK PAK Neurological Disease Inflammation/Immunology
    Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects .
    Gardenin A
  • HY-P3645

    Melanocortin Receptor Others
    (Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment .
    (Nle4)-α-MSH
  • HY-P3952

    Somatostatin Receptor Metabolic Disease
    (D-Trp8,D-Cys14)-Somatostatin-14 is a Somatostatin synthetic analogue. (D-Trp8,D-Cys14)-Somatostatin-14 can be used for the research of metabolic related diseases .
    (D-Trp8,D-Cys14)-Somatostatin-14
  • HY-16247

    HE3235

    Biochemical Assay Reagents Cancer
    Apoptone, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. Apoptone is active in rodent models of prostate and breast cancer . Apoptone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Apoptone
  • HY-13589

    LU103793 free base

    Microtubule/Tubulin Cancer
    Cemadotin (LU103793) is a water-soluble synthetic analogue of Dolastatin 15 (HY-P1126) that inhibits cell proliferation in vitro and the growth of tumor xenografts in mice. Cemadotin blocks cells at mitosis, and exhibits Ki value of 1 μM for inhibiting tubulin. Cemadotin can be used to research anticancer .
    Cemadotin
  • HY-13589A

    LU103793 hydrochloride

    Microtubule/Tubulin Cancer
    Cemadotin (LU103793) hydrochloride is a water-soluble synthetic analogue of Dolastatin 15 (HY-P1126) that inhibits cell proliferation in vitro and the growth of tumor xenografts in mice. Cemadotin hydrochloride blocks cells at mitosis, and exhibits Ki value of 1 μM for inhibiting tubulin. Cemadotin hydrochloride can be used to research anticancer .
    Cemadotin hydrochloride
  • HY-A0195R

    Prostaglandin Receptor Endocrinology
    Carboprost (tromethamine) (Standard) is the analytical standard of Carboprost (tromethamine). This product is intended for research and analytical applications. Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
    Carboprost tromethamine (Standard)
  • HY-118189

    Prostaglandin Receptor Inflammation/Immunology
    Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers . Misoprostol is an oral agent used to induce labor .
    Misoprostol acid
  • HY-15582

    Microtubule/Tubulin ADC Cytotoxin Cancer
    Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .
    Auristatin E
  • HY-P0036
    Octreotide
    10+ Cited Publications

    SMS 201-995

    Somatostatin Receptor Apoptosis Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide
  • HY-P0036B

    SMS 201-995 pamoate

    Somatostatin Receptor Apoptosis Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide (SMS 201-995) pamoate is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide pamoate can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide pamoate increases Gi activity and reduces intracellular cAMP production. Octreotide pamoate has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide pamoate
  • HY-P1640

    Complement System Inflammation/Immunology
    (Trp63,Trp64)​-​C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca 2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively .
    (Trp63,Trp64)​-​C3a(63-77)
  • HY-109520

    Others Inflammation/Immunology Cancer
    Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression .
    Glatiramer acetate
  • HY-N2466A

    MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate

    Melanocortin Receptor Cancer
    Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research .
    Melanotan I acetate
  • HY-118189S

    Isotope-Labeled Compounds Prostaglandin Receptor Inflammation/Immunology
    Misoprostol acid-d5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
    Misoprostol acid-d5
  • HY-N2466
    Melanotan I
    1 Publications Verification

    MT-I; [Nle4,D-Phe7]-α-MSH

    Melanocortin Receptor Neurological Disease Cancer
    Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .
    Melanotan I