Search Result
Results for "
the carrier
" in MedChemExpress (MCE) Product Catalog:
68
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-124452
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Desferrioxamine E; Nocardamin
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Bacterial
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Others
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Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
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-
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- HY-Y1888
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-
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- HY-100705
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6-Nitroveratraldehyde
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Others
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Neurological Disease
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DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[ 18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems .
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- HY-101540
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-
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- HY-W800782
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Liposome
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Others
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DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .
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- HY-157174
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Others
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Inflammation/Immunology
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Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research .
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- HY-111605
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Radionuclide-Drug Conjugates (RDCs)
ADC Linker
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Cancer
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Macropa-NCS can be coupled with antibodies to form tumor-selective carrier molecules, which can be further combined with radionuclides as specific targeting cancer cell carriers, and is a linker-chelating agent in targeted alpha research (TAT) .
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-
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- HY-145614
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Others
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Others
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Sucistil is an active compound. hemoglobin sucistil (bovine) is an oxygen carrier .
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-
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- HY-126605
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Bacterial
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Infection
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Trinactin is a macrotetrolide antibiotic. Trinactin also is a cation carrier .
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-
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- HY-101744
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Autophagy
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Inflammation/Immunology
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Ipsalazide is a novel sulfasalazine analog designed to release 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract.
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-
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- HY-44680
-
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Others
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Cancer
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L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery .
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-
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- HY-W102590
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Biochemical Assay Reagents
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Others
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DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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-
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- HY-W969553
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Others
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Others
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Sebacamic acid is a bioactive compound that can be used to synthesize cell delivery carriers with antioxidant activity and cellular uptake .
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-
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- HY-157187
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Others
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Others
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Fenhexamid-1-pentanoic acid is a hapten that can be covalently coupled to a carrier protein for the determination of cyclohexamide residues .
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-
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- HY-W783680
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Potassium Channel
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Others
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Potassium ionophore III (BME-44) is a specific potassium ion carrier with high selectivity for sodium and ammonium ions and high lipophilicity .
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-
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- HY-N2522
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Gummiferin dipotassium
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Others
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Others
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Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport .
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- HY-W004649
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Biochemical Assay Reagents
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Others
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Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-W402032
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Biochemical Assay Reagents
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Others
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Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-144006
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14:0 PEG2000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
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Liposome
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Others
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DMPE-PEG2000 (14:0 PEG2000 PE) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .
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- HY-153770
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- HY-157183
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Others
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Inflammation/Immunology
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HSMO9 is a (+)-methamphetamine (METH)-like hapten that can be coupled to a carrier protein. HSMO9 can be used in vaccine development .
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- HY-Y0873O
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Polyethylene glycol 35000
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Biochemical Assay Reagents
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Others
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PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .
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- HY-159717
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Liposome
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Others
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Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .
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- HY-112111
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Others
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Cancer
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Poly-L-Glutamic acid (MW 700000) is biochemical reagent.Poly-L-Glutamic acid can be used as the drug carrier for targeted delivery of anticancer agents .
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- HY-144027
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Biochemical Assay Reagents
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Others
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Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .
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- HY-113400
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Cytidine diphosphate
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Endogenous Metabolite
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Others
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Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
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- HY-157193
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-
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- HY-161005
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Others
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Metabolic Disease
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TETS-Methyl benzoate(compound 2j) is a haptendirectly conjugated to the carrier protein via carboxylic acid function using the standard activated ester method .
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- HY-B1884
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Fungal
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Infection
Inflammation/Immunology
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Procymidone, a pesticide, is an immunogen hapten that can be combined with cOVA (carrier protein) to produce polyclonal antibodies. Procymidone has antifungal activity .
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- HY-W008940
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Cytidine diphosphate disodium
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Endogenous Metabolite
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Metabolic Disease
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Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
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- HY-W440698
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Liposome
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Cancer
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Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
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- HY-D0217
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Bromosulfophthalein disodium salt
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Fluorescent Dye
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Metabolic Disease
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Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
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- HY-W013794
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N,N′-Bis(salicylidene)ethylenediaminocobalt(II)
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Others
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Infection
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Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O2 and oxidation catalysts. Salcomine has anti-influenza virus activity .
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- HY-108247
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-
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- HY-159714
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Liposome
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Others
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Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA .
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- HY-159715
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Liposome
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Others
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Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA .
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- HY-159716
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Liposome
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Others
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Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .
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- HY-120884
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Bacterial
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Infection
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InhA-IN-5 (compound 1) is a potent Mycobacterial tuberculosis (Mtb) trans-2-enoyl-acyl carrier protein reductase (InhA) inhibitor .
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- HY-137172
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Others
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Others
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ETH 157 is a Na + selective microelectrode based on a synthetic neutral carrier that is selective enough for K +, Ca 2+, and Mg 2+ for extracellular measurements of Na+ activity .
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- HY-118205
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Others
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Infection
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SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test.
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- HY-B0800
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Guanethidine monosulfate
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Adrenergic Receptor
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Neurological Disease
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Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
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- HY-144008
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Liposome
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Others
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C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
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- HY-126393
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Biochemical Assay Reagents
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Others
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Carboxymethyl-β-cyclodextrin, 99% is a cationic cyclodextrin used as a carrier for drugs. It has been shown to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity.
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- HY-Y1903
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Biochemical Assay Reagents
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Others
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Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient .
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- HY-W127846
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Biochemical Assay Reagents
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Others
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4',4 "(5")-Di-tert-butyldibenzo-18-crown-6 is an ionic carrier that can be used for the determination of potassium ions in artificial serum .
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- HY-B1147
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Parasite
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Infection
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Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
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- HY-144008A
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Liposome
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Others
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C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
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- HY-144004
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DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
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Liposome
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Others
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-155498
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GABA Receptor
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Neurological Disease
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TETS-4-Methylaniline (compound 2k) is a hapten. TETS-4-Methylaniline conjugates to the carrier protein via using either diazotization or glutaraldehyde methods .
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- HY-111071
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CG-400549
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Bacterial
Antibiotic
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Infection
Inflammation/Immunology
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Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin .
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- HY-Y0873B
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Polyethylene glycol 2000
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Biochemical Assay Reagents
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Others
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PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances. PEG2000 can be used as a carrier material and modifying agent. PEG2000 is widely used in a variety of pharmaceutical formulations .
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- HY-Y0873N
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Polyethylene glycol 3000
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Biochemical Assay Reagents
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Others
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PEG3000 (Polyethylene glycol 3000) is a solvent for a large number of substances. PEG3000 can be used as a carrier material and modifying agent. PEG3000 is widely used in a variety of pharmaceutical formulations .
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- HY-119749
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Bacterial
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Infection
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Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL .
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- HY-B1119
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Bacterial
Fungal
Antibiotic
Apoptosis
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Infection
Cancer
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Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
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- HY-15475
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PF-1005023
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Mitochondrial Metabolism
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Cancer
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UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
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- HY-140740
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Liposome
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Cancer
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DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-113736
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Amino Acid Derivatives
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Others
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Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
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- HY-144008B
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Biochemical Assay Reagents
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Others
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C8 PEG750 Ceramide is a lipid product. C8 PEG750 Ceramide synthesizes a lipid bilayer carrier for the selective delivery of various diagnostic and therapeutic agents to acidic diseased cells .
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- HY-113400S3
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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Cytidine diphosphate-d13 dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-160473A
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Microtubule/Tubulin
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Cancer
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TAM557 TFA is a cytotoxic tubulysin compounds, which is modified to be used for conjugation to transport vehicles that are targeting molecules, such as proteins, peptides, small molecules or polymeric carriers which can carry a targeting principle .
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- HY-155442
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Others
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Inflammation/Immunology
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MIQ-N-succinate is a hapten with a four-carbon chain. MIQ-N-succinate consist of MIQ and succinic anhydride. MIQ-N-succinate has a carboxylic acid end group to attach to the lysine residues on the carrier proteins .
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- HY-113400S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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Cytidine diphosphate- 15N3 dilithium is 15N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-W402682
-
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Others
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Neurological Disease
Cancer
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SXC2023 is an inhibitor for solute carrier family 7 member 11 (SLC7A11). SXC2023 exhibits antitumor efficacy, and ameliorates central nervous system disorder through downregulation of glutamate export .
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- HY-120649
-
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Biochemical Assay Reagents
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Others
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SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .
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- HY-148657
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NHS-Methotrexate
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Others
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Inflammation/Immunology
Cancer
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Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible
Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia) .
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- HY-113400S1
-
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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Cytidine diphosphate- 13C9 dilithium is 13C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-19514
-
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Others
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Cancer
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Fosfluridine Tidoxil is comprised of a specific carrier molecule, coupled through a phosphate group to 5-Fluorouridine (5-FUrd), a metabolite of 5- Fluorouracil (5-FU). Fosfluridine Tidoxil is a oral active anticancer agent .
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- HY-N2522R
-
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Others
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Others
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Carboxyatractyloside (dipotassium) (Standard) is the analytical standard of Carboxyatractyloside (dipotassium). This product is intended for research and analytical applications. Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport .
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- HY-B1884R
-
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Fungal
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Infection
Inflammation/Immunology
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Procymidone (Standard) is the analytical standard of Procymidone. This product is intended for research and analytical applications. Procymidone, a pesticide, is an immunogen hapten that can be combined with cOVA (carrier protein) to produce polyclonal antibodies. Procymidone has antifungal activity .
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- HY-163025
-
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Others
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Inflammation/Immunology
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Cyanazine-3-mercaptopropanoic acid (compound 6), a coating hapten, is a stable carrier-hapten complex. Polyclonal antibody obtained were with a high titer, with the IC50 of 10.2 ng/mL for Cyanazine-3-mercaptopropanoic acid .
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- HY-B1119R
-
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Bacterial
Fungal
Antibiotic
Apoptosis
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Infection
Cancer
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Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
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- HY-144011
-
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Liposome
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Others
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DSPE-PEG-Cyanur is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur can be used for nanostructured lipid carrier .
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- HY-P4205
-
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Aminopeptidase
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Cancer
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Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission. Aminopeptidase N Ligand (CD13) NGR peptide is often used in cancer research .
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- HY-B0486
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- HY-100550
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Mitoglitazone; CAY10415
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Insulin Receptor
Mitochondrial Metabolism
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Neurological Disease
Endocrinology
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MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease .
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- HY-W440916
-
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Liposome
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Others
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DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440915
-
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Liposome
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Others
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DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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-
- HY-W440917
-
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Liposome
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Others
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DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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-
- HY-D1005A11
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PEG-PPG-PEG, 3400 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 185 P65 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 3400. Poloxamer 185 P65 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-D1005A12
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PEG-PPG-PEG, 2750 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 212 L72 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2750. Poloxamer 212 L72 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-D1005A13
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PEG-PPG-PEG, 4150 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 215 P75 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4150. Poloxamer 215 P75 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-D1005A15
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PEG-PPG-PEG, 4200 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 234 P84 is is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4200. Poloxamer 234 P84 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-D1005A2
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PEG-PPG-PEG, 1900 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-D1005A20
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PEG-PPG-PEG, 5900 (Averag)
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Biochemical Assay Reagents
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Others
|
Poloxamer 334 P104 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 5900. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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-
- HY-D1005A5
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PEG-PPG-PEG, 1850 (Averag)
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Biochemical Assay Reagents
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Others
|
Poloxamer 123 L43 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1850. Poloxamer 123 L43 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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-
- HY-D1005A7
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PEG-PPG-PEG, 2400 (Averag)
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Biochemical Assay Reagents
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Others
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Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
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- HY-N1502
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Gummiferin tripotassium
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Others
|
Cancer
|
Carboxyatractyloside (Gummiferin) tripotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport from the inner mitochondria to the inner mitochondria. Carboxyatractyloside tripotassium can be used for the study of cellular energy metabolism and mitochondrial biology .
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- HY-149691
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MFH
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Biochemical Assay Reagents
|
Inflammation/Immunology
|
6-(N-Phthalimidoylmethylthio)hexanoic acid (MFH) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 6-(N-Phthalimidoylmethylthio)hexanoic acid can be combined with carrier proteins and used in antigen design .
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- HY-149690
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MFA
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Biochemical Assay Reagents
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Inflammation/Immunology
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2-(N-Phthalimidoylmethylthio)acetic acid (MFA) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 2-(N-Phthalimidoylmethylthio)acetic acid can be combined with carrier proteins and used in antigen design .
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- HY-161006
-
|
Others
|
Inflammation/Immunology
|
(S)-TETS-C4-acid (Compound 2d) is a hapten coupled directly to a carrier protein through a carboxylic acid functionality. (S)-TETS-C4-acid (Compound 2d) can be used to detect tetramethylenedisulfotetramine (TETS) .
|
-
- HY-151510
-
|
Liposome
|
Others
|
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .
|
-
- HY-10824
-
PT523
|
Antifolate
Dihydrofolate reductase (DHFR)
|
Cancer
|
Talotrexin (PT523), an analog of Aminopterin (HY-14518), is a nonpolyglutamatable classic antifolate. Talotrexin is a RFC (reduced folate carrier) specific inhibitor and selectively inhibits RFC transport. Talotrexin shows antitumor activity by targeting DHFR to inhibit tumor growth .
|
-
- HY-W028210
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
6-N-Phthalimidoy hexanoic acid (compound FH) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 6-N-Phthalimidoy hexanoic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-W046063
-
4-Phthalimidobutyric acid
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
4-(N-Phthalimidoyl)butanoic acid (compound FB) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 4-(N-Phthalimidoyl)butanoic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-113400S2
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
Cytidine diphosphate- 13C9, 15N3 dilithium is 13C and 15N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
- HY-B0800R
-
|
Adrenergic Receptor
|
Neurological Disease
|
Guanethidine (sulfate) (Standard) is the analytical standard of Guanethidine (sulfate). This product is intended for research and analytical applications. Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
|
-
- HY-W440928
-
|
Biochemical Assay Reagents
Liposome
|
Others
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-128851
-
|
Fatty Acid Synthase (FASN)
Endogenous Metabolite
|
Metabolic Disease
|
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
|
-
- HY-128851A
-
|
Endogenous Metabolite
Fatty Acid Synthase (FASN)
|
Metabolic Disease
|
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
|
-
- HY-128851B
-
|
Endogenous Metabolite
Fatty Acid Synthase (FASN)
|
Metabolic Disease
|
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
|
-
- HY-W440815
-
|
Liposome
|
Others
|
6-((4-Hydroxybutyl)amino)hexyl 2-hexyldecanoate is a lipid, it can be used to synthesis nanomaterials. 6-((4-Hydroxybutyl)amino)hexyl provides the use of the nano-lipid particle as the key component in nucleic acid delivery, including the components of the delivery carrier .
|
-
- HY-144004A
-
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
- HY-D1137
-
|
Fluorescent Dye
|
|
C.I. Pigment yellow 110 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0960
-
|
Fluorescent Dye
|
|
C.I. Solvent Blue 43 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0725
-
|
Fluorescent Dye
|
|
C.I. Pigment yellow 180 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0686
-
|
Fluorescent Dye
|
|
C.I. Pigment red 221 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0531
-
|
Fluorescent Dye
|
|
C.I. Pigment red 123 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0510
-
|
Fluorescent Dye
|
|
C.I. Pigment orange 34 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0493
-
|
Fluorescent Dye
|
|
C.I. Pigment yellow 62 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0489
-
|
Fluorescent Dye
|
|
C.I. Pigment orange 38 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0488
-
|
Fluorescent Dye
|
|
C.I. Pigment orange 36 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0486
-
|
Fluorescent Dye
|
|
C.I. Pigment violet 32 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0460
-
Pigment red 48 calcium salt
|
Fluorescent Dye
|
|
C.I. Pigment red 48 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0459
-
|
Fluorescent Dye
|
|
C.I. Pigment brown 25 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0457
-
|
Fluorescent Dye
|
|
C.I. Solvent red 179 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0450
-
|
Fluorescent Dye
|
|
C.I. Pigment red 112 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0445
-
|
Fluorescent Dye
|
|
C.I. Pigment orange 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0442
-
|
Fluorescent Dye
|
|
C.I. Pigment red 14 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0441
-
|
Fluorescent Dye
|
|
C.I. Pigment red 23 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0433
-
Navy Blue G
|
Fluorescent Dye
|
|
C.I. Vat Blue 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0431
-
|
Fluorescent Dye
|
|
C.I. Pigment blue 56 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0429
-
|
Fluorescent Dye
|
|
C.I. Pigment red 5 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0428
-
|
Fluorescent Dye
|
|
C.I. Pigment red 9 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0427
-
|
Fluorescent Dye
|
|
C.I. Pigment red 12 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0426
-
|
Fluorescent Dye
|
|
C.I. Pigment red 8 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0421
-
|
Fluorescent Dye
|
|
C.I. Solvent yellow 18 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0415
-
|
Fluorescent Dye
|
|
C.I. Vat blue 22 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0408
-
|
Fluorescent Dye
|
|
C.I. Pigment red 38 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0405
-
|
Fluorescent Dye
|
|
C.I. Pigment yellow 74 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0394
-
|
Fluorescent Dye
|
|
C.I. Pigment red 2 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0392
-
|
Fluorescent Dye
|
|
C. I. Pigment yellow 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-W587753
-
|
Antibiotic
Bacterial
|
Infection
|
Bacitracin A is an antibiotic, which exhibits antibacterial activity against gram-positive bacteria. Bacitracin A forms complex with long-chain polyisoprenyl pyrophosphates in presence of metal ions, dephosphorylates the lipid carrier intermediate Css-bactoprenyl pyrophosphate, inhibits thus the bacterial cell wall biosynthesis .
|
-
- HY-138962
-
K-Carrageenan Karra Type
|
Apoptosis
|
Inflammation/Immunology
Cancer
|
κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective agent carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation .
|
-
- HY-Y1091
-
|
Endogenous Metabolite
|
Others
|
D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance .
|
-
- HY-149751
-
|
Others
|
Others
|
Methylthiomcresol-C5-COOH (Compound F4) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C5-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
|
-
- HY-149749
-
|
Others
|
Others
|
Methylthiomcresol-C3-COOH (Compound F2) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C3-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
|
-
- HY-D0519
-
|
Fluorescent Dye
|
|
C.I. Pigment red 52:1 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-B1147R
-
|
Parasite
|
Infection
|
Diloxanide furoate (Standard) is the analytical standard of Diloxanide furoate. This product is intended for research and analytical applications. Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
|
-
- HY-106407
-
Org 4428; ADL 6906
|
Adrenergic Receptor
5-HT Receptor
|
Neurological Disease
|
Beloxepin (Org 4428) is an orally active synaptosomal noradrenalin reuptake inhibitor and a 5-HT2 receptor antagonist. Beloxepin shows about 100-fold less affine for other monoamine carriers. Beloxepin has antidepressant and pain-relieving effects .
|
-
- HY-144005
-
C16 PEG Ceramide (MW 2000)
|
Liposome
Autophagy
|
Cancer
|
C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research .
|
-
- HY-14830
-
Albitiazolium bromide
|
Parasite
|
Infection
|
SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC). SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier .
|
-
- HY-W008940R
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
|
-
- HY-D0835
-
Hydroxyapatite (25-45μm)
|
Biochemical Assay Reagents
|
Others
|
Hydroxylapatite (Hydroxyapatite) is a naturally occurring calcium phosphate which is a major mineral component of bone and teeth bones. Nano-scale Hydroxylapatite particles are increasingly being used as carriers for controlled and targeted delivery of bioactive agents like agents, proteins, and nucleic acids due to their high porosity, negative charge, and biodegradability .
|
-
- HY-151941
-
|
Bacterial
|
Infection
|
MtInhA-IN-1 is a selective and orally active Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhibitor with an IC50 of 0.23 μM. MtInhA-IN-1 potently against M. tuberculosis H37Rv strain with a MIC value of 0.4 μM .
|
-
- HY-B1250
-
|
Biochemical Assay Reagents
|
Cancer
|
Acedoben is a biochemical agent. Acedoben and iron ions can construct a fast self-assembled coordination complex. The Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties .
|
-
- HY-113003
-
γ-Glutamylglutamine; γ-Glu-Gln
|
Others
|
Others
Cancer
|
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .
|
-
- HY-156598
-
|
Others
|
Others
|
1,3-Bis (carboxyphenoxy) propane is one of the monomer raw materials for aromatic polyanhydrides. 1,3-Bis (carboxyphenoxy) propane has been used as biodegradable carriers for drug delivery applications. 1,3-Bis (carboxyphenoxy) can be used for implant related research .
|
-
- HY-N7103R
-
|
Others
|
Others
|
Ethyl oleate (Standard) is the analytical standard of Ethyl oleate. This product is intended for research and analytical applications. Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration .
|
-
- HY-B1250A
-
|
Biochemical Assay Reagents
|
Cancer
|
Acedoben sodium is the sodium salt form of Acedoben. Acedoben and iron ions can construct a rapidly self-assembled coordination complex, and the Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties .
|
-
- HY-160679
-
|
Bacterial
|
Infection
|
BaENR-IN-1 (Compound 5) is an inhibitor of Enoyl-Acyl Carrier Protein Reductase (ENR) (IC50= 7.7 μM). BaENR-IN-1 blocks the synthesis of fatty acids essential for bacterial growth by inhibiting the bacterial enzyme ENR. BaENR-IN-1 shows activity against bacteria .
|
-
- HY-108022
-
-
- HY-Y0873M
-
Polyethylene glycol 500
|
Biochemical Assay Reagents
|
Others
|
PEG500 (Polyethylene glycol 500) is a versatile polymer that's used as a solvent, dispersant, lubricant, and more in industries like pharmaceuticals and biotechnology, and it can also modify liposomes. PEG500 is commonly used as a solvent or carrier for drugs, helping with capsule endoscopy to improve image quality and cecum completion rates .
|
-
- HY-160678
-
|
Bacterial
|
Infection
|
InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM .
|
-
- HY-44134
-
Dimethyl α-ketoglutarate
|
Endogenous Metabolite
|
Others
|
Dimethyl 2-oxoglutarate serves as a crucial intermediate in the Krebs cycle and an essential nitrogen carrier in metabolic pathways during biological processes. The electrochemical behavior of Dimethyl 2-oxoglutarate can be investigated using cyclic voltammetry, square wave voltammetry, and differential pulse voltammetry with a glassy carbon electrode .
|
-
- HY-W339838
-
14:0 Lyso PG
|
Liposome
|
Cancer
|
1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-146171
-
|
Bacterial
|
Infection
|
FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant .
|
-
- HY-W026082
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
4-Ketobenztriazine-CH2COOH (compound BA) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 4-Ketobenztriazine-CH2COOH can be combined with carrier proteins and used in antigen design .
|
-
- HY-147332
-
|
Liposome
|
Neurological Disease
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
-
- HY-134421
-
|
Biochemical Assay Reagents
|
Others
|
2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ) .
|
-
- HY-155880
-
mPEG-NH2 (MW 350)
|
Biochemical Assay Reagents
|
Cancer
|
mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155881
-
mPEG-NH2 (MW 550)
|
Biochemical Assay Reagents
|
Cancer
|
mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155882
-
mPEG-NH2 (MW 750)
|
Biochemical Assay Reagents
|
Cancer
|
mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155883
-
mPEG-NH2 (MW 3400)
|
Biochemical Assay Reagents
|
Cancer
|
mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-157186
-
|
Others
|
Inflammation/Immunology
|
(22R)-33,34,35-Trinorbacteriohopan-32-oic acid (compound 2c) is a hapten that can be covalently coupled to a carrier protein. (22R)-33,34,35-Trinorbacteriohopan-32-oic acid can be used in antibody generation and immunoassay .
|
-
- HY-D1005A17
-
PEG-PPG-PEG, 11400 (Averag)
|
Biochemical Assay Reagents
|
Others
|
Poloxamer 238 F88 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 11400. Poloxamer 238 F88 reduces the aggregation of red blood cells. Poloxamer 238 F88 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-B0486R
-
|
Hexokinase
Mitochondrial Metabolism
Apoptosis
Parasite
|
Inflammation/Immunology
Cancer
|
Lonidamine (Standard) is the analytical standard of Lonidamine. This product is intended for research and analytical applications. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis .
|
-
- HY-N7374
-
|
Others
|
Infection
|
Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola. It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50=89 μM). Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50=38.4 μM).
|
-
- HY-145505
-
18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol
|
Endogenous Metabolite
Liposome
|
Metabolic Disease
|
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-155884
-
mPEG-NH2 (MW 4000)
|
Biochemical Assay Reagents
|
Cancer
|
mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-10824A
-
PT523 monoammonium
|
Dihydrofolate reductase (DHFR)
Antifolate
|
Cancer
|
Talotrexin monoammonium is the monoammonium salt form of Talotrexin (HY-10824). Talotrexin monoammonium is an analog of Aminopterin (HY-14518), and is a nonpolyglutamatable classic antifolate. Talotrexin monoammonium is a reduced folate carrier (RFC) specific inhibitor and selectively inhibits RFC transport. Talotrexin monoammonium shows antitumor activity by targeting DHFR to inhibit tumor growth .
|
-
- HY-N7232
-
|
Reverse Transcriptase
|
Infection
|
Limochromin is a pigment produced by Streptomyces limosus that strongly inhibits the reverse transcriptase of avian myeloid leukemia virus (AMV). The inhibitory activity of limochromin is not affected by changes in the concentration of template-primer, substrate or carrier protein, but its inhibitory effect is significantly reduced when the concentration of AMV reverse transcriptase increases. Limochromin can be used to develop antiviral treatments .
|
-
- HY-W115607
-
Poly(ethylene glycol)-bis-amine (MW 8000)
|
Biochemical Assay Reagents
|
Cancer
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W591632
-
Poly(ethylene glycol)-bis-amine (MW 1000)
|
Biochemical Assay Reagents
|
Cancer
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-138241
-
|
Fluorescent Dye
|
Others
|
PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance at 591 nm. PBD-BODIPY has been used to measure the activity of radical-trapping antioxidants in cell-free assays. It has also been used as a fluorescent probe for the detection of epoxidation activity.
|
-
- HY-W440884
-
|
Biochemical Assay Reagents
|
Others
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W440907
-
|
Biochemical Assay Reagents
|
Others
|
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-I0606B
-
|
Others
|
|
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chiral molecule with potential chiral catalytic activity. It can be used as an intermediate in organic synthesis and plays a key role in the construction of complex molecular systems. This compound has also been used to develop new compound carriers and exhibits good biocompatibility.
|
-
- HY-126304
-
|
Phosphatase
Endogenous Metabolite
ERK
|
Metabolic Disease
|
β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .
|
-
- HY-W011391
-
|
Apoptosis
ASCT
|
Cancer
|
GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na +-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na +-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells .
|
-
- HY-W474473
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid (MFP) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-D1005A19
-
PEG-PPG-PEG, 4950 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Poloxamer 333 P103 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4950. Poloxamer 333 P103 exhibits antimicrobial activity, that inihibits 90% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 333 P103 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A4
-
PEG-PPG-PEG, 1630 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A8
-
PEG-PPG-PEG, 2000 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Poloxamer 181 L61 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2000. Poloxamer 181 L61 exhibits antimicrobial activity, that inihibits 91% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 181 L61 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A9
-
PEG-PPG-PEG, 2650 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Poloxamer 183 L63 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2650. Poloxamer 183 L63 exhibits antimicrobial activity, that inihibits 83% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 183 L63 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-158090
-
|
Others
|
Cancer
|
Triptolide palmitate is the derivative of Triptolide (HY-32735). Triptolide palmitate exhibits cytotoxicity against cancer cell MCF-7 and A549, with IC50 of 7.5 and 6.4 μM. Triptolide palmitate exhibits a half-time T1/2 of 50.4 min in Sprague Dawley rats. Triptolide palmitate can be utilizd as drug carrier .
|
-
- HY-145506
-
18:0 Lyso PG sodium
|
Liposome
|
Metabolic Disease
|
1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-145507
-
1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)
|
Liposome
|
Metabolic Disease
|
1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-D0886
-
|
Phosphatase
Endogenous Metabolite
ERK
|
Metabolic Disease
Cancer
|
β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .
|
-
- HY-138559
-
|
Mitochondrial Metabolism
|
Neurological Disease
|
GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates. GW604714X is a highly specific mitochondrial pyruvate carrier (MPC) inhibitor with a Ki <0.1 nM. GW604714X also inhibits L-lactate transport by the plasma membrane monocarboxylate transporter (MCT1), but at concentrations more than 4 orders of magnitude greater than the MPC .
|
-
- HY-B2247A
-
poly(lactic-co-glycolic acid) (75:25)
|
Biochemical Assay Reagents
|
Others
|
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
|
-
- HY-E70319
-
Immobilized cephalosporin C or 7-ACA esterase
|
Endogenous Metabolite
|
Others
|
AMK-EX (Immobilized cephalosporin C or 7-ACA esterase) is an immobilized enzyme, among which cephalosporin C C/7-ACA esterase is a type of enzyme that can hydrolyze the ester bond of cephalosporin C or 7-ACA. Immobilized enzyme is a technology that immobilizes enzymes on carriers, which can be easily separated and recovered, improving the stability, activity and reusability of enzymes .
|
-
- HY-W587552
-
|
Others
|
|
1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.
|
-
- HY-W440903
-
|
Biochemical Assay Reagents
|
Others
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-W440926
-
|
Biochemical Assay Reagents
Liposome
|
Others
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-13728
-
ZD 9331; BGC9331
|
Thymidylate Synthase
|
Cancer
|
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156214
-
AP1867-PEG2-JQ1; AP-PEG2-JQ1
|
Others
|
Others
|
NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that bind to proteins in separate cellular compartments that can induce nuclear import of cytosolic cargoes, using nuclear-localized bromodomain-containing protein 4 (BRD4) as a “carrier” for co-import and nuclear trapping of cytosolic proteins .
|
-
- HY-157194
-
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50=25µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research .
|
-
- HY-D1005A6
-
PEG-PPG-PEG, 2200 (Averag)
|
Biochemical Assay Reagents
|
Others
|
Poloxamer 124 L44 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2200. Poloxamer 124 L44 reveals toxicity with an oral LD50 of 5 g/kg in albino rats. Poloxamer 124 L44 causes ocular irritation. Poloxamer 124 L44 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-108022A
-
MSDC-0602K
|
Insulin Receptor
PPAR
|
Metabolic Disease
|
Azemiglitazone potassium (MSDC-0602K), a PPARγ-sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC50 of 18.25 μM . Azemiglitazone potassium modulates the mitochondrial pyruvate carrier (MPC). Azemiglitazone potassium can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance . Azemiglitazone potassium, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide .
|
-
- HY-144825
-
|
Apoptosis
Reactive Oxygen Species
|
Cancer
|
Chol-CTPP is a ligand with dual targeting effect on blood-brain barrier (BBB) and glioma cells. Lip-CTPP can be gained by Chol-CTPP and another mitochondria targeting ligand (Chol-TPP). Lip-CTPP is a promising potential carrier to exert the anti-glioma effect of doxorubicin (DOX) and lonidamine (LND) collaboratively. Lip-CTPP elevates the inhibition rate of tumor cell proliferation, migration and invasion, promote apoptosis and necrosis, and interfere with mitochondrial function .
|
-
- HY-149689
-
HBA
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
2-[(4-Oxo-1,2,3-benzotriazin-3-yl)oxy]acetic acid (HBA) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 2-[(4-Oxo-1,2,3-benzotriazin-3-yl)oxy]acetic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-149688
-
MBH
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
6-[(4-Oxo-1,2,3-benzotriazin-3-yl)methylthio]hexanoic acid (MBH) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 6-[(4-Oxo-1,2,3-benzotriazin-3-yl)methylthio]hexanoic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-149687
-
MBP
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
3-[(4-Oxo-1,2,3-benzotriazin-3-yl)methylthio]propanoic acid (MBP) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 3-[(4-Oxo-1,2,3-benzotriazin-3-yl)methylthio]propanoic acid can be combined with carrier proteins and used in antigen design .
|
-
- HY-D1005A21
-
PEG-PPG-PEG, 6500 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Poloxamer 335 P105 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 6500. Poloxamer 335 P105 exhibits antimicrobial activity, that inihibits 86% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 334 P104 exhibits muscular toxicity. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-B0240
-
Tetraethylthiuram disulfide; TETD
|
Aldehyde Dehydrogenase (ALDH)
Interleukin Related
Pyroptosis
Apoptosis
Cuproptosis
|
Metabolic Disease
Cancer
|
Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu 2+ increases intracellular ROS levels and induces cuproptosis .
|
-
- HY-123986
-
|
Mitochondrial Metabolism
|
Inflammation/Immunology
Cancer
|
CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity .
|
-
- HY-127146
-
|
Antibiotic
Bacterial
|
Infection
|
Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
|
-
- HY-137234
-
2,6-Di-O-methyl-β-cyclodextrin
|
Biochemical Assay Reagents
|
Others
|
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
|
-
- HY-W588717
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-154629
-
|
Biochemical Assay Reagents
|
Others
Cancer
|
Sesame Oil can be used as an excipient, such as Oil-soluble substance carrier, solvent, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-124357
-
S-Norfluoxetine hydrochloride; LY 215229 hydrochloride
|
Others
|
Neurological Disease
|
Seproxetine (S-Norfluoxetine) hydrochloride is a selective serotonin reuptake inhibitor (SSRI) that enhances serotonin levels in the brain by specifically inhibiting the serotonin uptake carrier. Seproxetine hydrochloride exhibits strong charge transfer interactions with π-electron acceptors, forming stable complexes that enhance its binding affinity to multiple receptors, including serotonin and dopamine receptors. Seproxetine hydrochloride demonstrates improved biological activity when interacting with charge transfer complexes, leading to increased stability and efficacy in therapeutic applications.
|
-
- HY-149276
-
|
GLUT
|
Metabolic Disease
|
SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
|
-
- HY-149802
-
|
GLUT
|
Metabolic Disease
|
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
|
-
- HY-Y1738
-
Tetrakis(triphenylphosphine)palladium(0)
|
Biochemical Assay Reagents
|
Others
|
Tetrakis(triphenylphosphine)palladium (Pd(PPhs)) series of cross-coupling catalysts can be used to construct an organic heterojunction solar cell model. Adding different amounts of Pd(PPhs) significantly affected free carrier generation, non-twin trap and surface trap-assisted recombination as well as bimolecular recombination and charge extraction, but the impact on the non-duplex recombination process was limited because the catalyst could not promote efficient Trap-assisted reorganization. The studied system is highly robust with the addition of a small amount of Pd(PPha) .
|
-
- HY-D1005A10
-
PEG-PPG-PEG, 2900 (Averag)
|
Biochemical Assay Reagents
Bacterial
|
Infection
Inflammation/Immunology
|
Poloxamer 184 L64 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2900. Poloxamer 184 L64 exhibts short-term dermal toxicity characterized by slight erythema and intradermal inflammatory response. Poloxamer 184 L64 exhibits antimicrobial activity, that inihibits 60% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 184 L64 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-158255
-
|
Biochemical Assay Reagents
|
Others
|
mPEG-PLGA (2000-80000) (LA/GA 50:50) is a copolymer, which consists of hydrophilic mPEG and biodegradable PLGA (molar ratio is 50:50) with a molecular weight of 2000 (mPEG) + 80000 (PLGA). mPEG-PLGA (2000-80000) (LA/GA 50:50) forms nanoparticles or microparticles, which is stable in aqueous solution at different pH values and elevated temperatures as well as in serum. mPEG-PLGA (2000-80000) (LA/GA 50:50) is utilized as carrier material in drug delivery systems .
|
-
- HY-121746
-
|
PPAR
Calcium Channel
Apoptosis
|
Cardiovascular Disease
Metabolic Disease
|
GW7845 is an orally active non-thiazolidinedione, tyrosine-derived PPARγ agonist. GW7845 is effective at inhibiting voltage-dependent calcium channels (VDCC) and relaxing pressurized arteries with IC50 of 3 μM by using Ba 2+ as the charge carrier through VDCC. GW7845-induced apoptosis is mitochondria- and apoptosome-dependent. GW7845 induces rapid mitochondrial membrane depolarization and release of cytochrome c in primary pro-B cells and BU-11 cells .
|
-
- HY-162578
-
|
PPAR
|
Metabolic Disease
|
PPARα/γ agonist 4 (Compound (S)-7) is an orally active dual potent agonist of PPARα and PPARγ, with EC50 values of 0.061 μM and 1.42 μM respectively. PPARα/γ agonist 4 acts through an insulin-independent mechanism and exhibits mitochondrial pyruvate carrier inhibition and anti-diabetic properties. PPARα/γ agonist 4 is expected to be used in research for dyslipidemic type 2 diabetes .
|
-
- HY-137499
-
|
Liposome
Endogenous Metabolite
|
Neurological Disease
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
-
- HY-149979
-
|
Apoptosis
|
Cancer
|
SLC7A11-IN-1 is a potent solute carrier family 7 member 11 (SLC7A11, xCT) inhibitor. SLC7A11-IN-1 shows antiproliferative activity. SLC7A11-IN-1 inhibits cell invasion and metastasis. SLC7A11-IN-1 induces Apoptosis and cell cycle arrest at S-phase. SLC7A11-IN-1 shows anti-tumor activity .
|
-
- HY-112839
-
|
Endogenous Metabolite
|
|
1-Myristoyl-2-(4-nitrophenylsuccinyl)-sn-glycero-3-phosphocholine is a synthetic phospholipid with the activity of inhibiting cell proliferation. 1-Myristoyl-2-(4-nitrophenylsuccinyl)-sn-glycero-3-phosphocholine can be used as a compound carrier to increase the bioavailability of the compound. 1-Myristoyl-2-(4-nitrophenylsuccinyl)-sn-glycero-3-phosphocholine also plays an important role in cell membrane research and provides an effective tool for understanding cell signal transduction.
|
-
- HY-116282C
-
DSS (MW 35000-45000); DXS (MW 35000-45000)
|
HIV
Apoptosis
|
Infection
Inflammation/Immunology
|
Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose and is a potent inducer of colitis. Dextran sulfate sodium salt (MW 35000-45000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium. Dextran sulfate sodium salt (MW 35000-45000) also inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells. Dextran sulfate sodium salt (MW 35000-45000) is also used to bind to insulin, encapsulate it in gold nanoparticles, and serve as an insulin carrier to bind to insulin receptors to achieve the purpose of slowly releasing insulin and prolonging insulin activity .
|
-
- HY-147081
-
AGRO-100
|
Histone Methyltransferase
Bcl-2 Family
|
Cancer
|
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
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-
- HY-B0445R
-
|
Endogenous Metabolite
|
Metabolic Disease
|
NAD+ (Standard) is the analytical standard of NAD+. This product is intended for research and analytical applications. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
In Vitro: NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH . NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) .
In Vivo: Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia .
|
-
- HY-W011426
-
Propan-2-yl hexadecanoate
|
Biochemical Assay Reagents
Liposome
|
Others
|
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-W251143
-
|
Others
|
|
N,N′-Bis(2,5-di-tert-butylphenyl)-3,4,9,10-perylenedicarboximide is an organic semiconductor material with excellent electron transport activity. N,N′-Bis(2,5-di-tert-butylphenyl)-3,4,9,10-perylenedicarboximide is widely used in organic field effect transistors (OFETs) and organic photovoltaic (OPV) devices due to its high carrier mobility. The chemical structure design of N,N′-Bis(2,5-di-tert-butylphenyl)-3,4,9,10-perylenedicarboximide enables it to perform well in light absorption and photoelectric conversion, thereby improving the efficiency of organic photoelectric devices.
|
-
- HY-W251144
-
PTCDI-C5
|
Others
|
|
N,N′-Dipentyl-3,4,9,10-perylenedicarboximide (PTCDI-C5) is an organic semiconductor compound with excellent electron transport activity. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide exhibits high performance in organic field effect transistors (OFETs) and can effectively improve the carrier mobility of the device. The application of N,N′-Dipentyl-3,4,9,10-perylenedicarboximide in organic photovoltaic (OPV) materials enhances the light absorption performance, thereby improving the photoelectric conversion efficiency. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide has also been widely studied for the development of high-performance sensors and fluorescent materials.
|
-
- HY-P5439
-
|
PKC
MARCKS
|
Others
|
Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
|
-
- HY-W050154R
-
|
Parasite
Tyrosinase
NF-κB
CDK
|
Infection
Inflammation/Immunology
Cancer
|
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
|
-
- HY-W391671
-
|
Others
|
Others
|
Poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine], a type of poly(triaryl amine), serves as an organic p-type semiconductor exhibiting hole mobilities ranging from 10?3 to 10?2 cm2 V?1 s?1, which significantly enhances carrier mobility. This stable glassy polymer possesses a favorable ionization potential for thick film diodes. Committed to providing Greener Alternative Products that comply with one or more of The 12 Principles of Greener Chemistry, this material falls under the Enabling category of greener alternatives, aligning with the principle of "Design for energy efficiency." Additionally, while hole transport organic materials like this ensure optimal energy level alignment with the absorber layer for efficient charge collection, they may be susceptible to degradation under ambient conditions.
|
-
- HY-113225B
-
GTP tritris
|
Endogenous Metabolite
|
Cancer
|
Guanosine triphosphate tritris (GTP tritris) serves as a vital enhancer of myogenic cell differentiation and plays a critical role in modulating miRNA-myogenic regulator factors. It also facilitates the release of exosomes enriched with guanosine and guanosine-derived molecules, and is regarded as an activated precursor for RNA synthesis. In mitochondrial function, GTP participates in the import of proteins into the matrix, which is essential for various regulated pathways, and is involved in initiating peptide synthesis through the binding of formylmethionyl-tRNA to the ribosome, as well as polypeptide chain elongation. Additionally, GTP acts as a phosphate and pyrophosphate carrier that channels chemical energy into specific biosynthetic pathways. It activates signal transducing G proteins that regulate cellular processes such as proliferation and differentiation, and its hydrolysis by small GTPases, including Ras and Rho, is integral to both proliferation and apoptosis. Furthermore, the small GTPase Rab is instrumental in vesicle docking, fusion, and formation. Beyond signal transduction, GTP is an energy-rich precursor in the enzymatic biosynthesis of DNA and RNA.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0217
-
Bromosulfophthalein disodium salt
|
Dyes
|
Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
|
-
- HY-120649
-
|
Fluorescent Dyes/Probes
|
SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .
|
-
- HY-D1137
-
|
Dyes
|
C.I. Pigment yellow 110 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0960
-
|
Dyes
|
C.I. Solvent Blue 43 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0725
-
|
Dyes
|
C.I. Pigment yellow 180 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0686
-
|
Dyes
|
C.I. Pigment red 221 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0531
-
|
Dyes
|
C.I. Pigment red 123 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0510
-
|
Dyes
|
C.I. Pigment orange 34 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0493
-
|
Dyes
|
C.I. Pigment yellow 62 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0489
-
|
Dyes
|
C.I. Pigment orange 38 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0488
-
|
Dyes
|
C.I. Pigment orange 36 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0486
-
|
Dyes
|
C.I. Pigment violet 32 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0460
-
Pigment red 48 calcium salt
|
Dyes
|
C.I. Pigment red 48 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0459
-
|
Dyes
|
C.I. Pigment brown 25 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0457
-
|
Dyes
|
C.I. Solvent red 179 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0450
-
|
Dyes
|
C.I. Pigment red 112 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0445
-
|
Dyes
|
C.I. Pigment orange 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0442
-
|
Dyes
|
C.I. Pigment red 14 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0441
-
|
Dyes
|
C.I. Pigment red 23 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0433
-
Navy Blue G
|
Dyes
|
C.I. Vat Blue 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0431
-
|
Dyes
|
C.I. Pigment blue 56 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0429
-
|
Dyes
|
C.I. Pigment red 5 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0428
-
|
Dyes
|
C.I. Pigment red 9 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0427
-
|
Dyes
|
C.I. Pigment red 12 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0426
-
|
Dyes
|
C.I. Pigment red 8 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0421
-
|
Dyes
|
C.I. Solvent yellow 18 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0415
-
|
Dyes
|
C.I. Vat blue 22 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0408
-
|
Dyes
|
C.I. Pigment red 38 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0405
-
|
Dyes
|
C.I. Pigment yellow 74 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0394
-
|
Dyes
|
C.I. Pigment red 2 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0392
-
|
Dyes
|
C. I. Pigment yellow 16 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
-
- HY-D0519
-
|
Dyes
|
C.I. Pigment red 52:1 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
|
Cat. No. |
Product Name |
Type |
-
- HY-124452
-
Desferrioxamine E; Nocardamin
|
Chelators
|
Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
|
-
- HY-Y1888
-
Corn oil
Maximum Cited Publications
65 Publications Verification
|
Co-solvents
|
Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
|
-
- HY-W102590
-
|
Chelators
|
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
|
-
- HY-144006
-
14:0 PEG2000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
Drug Delivery
|
DMPE-PEG2000 (14:0 PEG2000 PE) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .
|
-
- HY-Y0873O
-
Polyethylene glycol 35000
|
Drug Delivery
|
PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .
|
-
- HY-NP133
-
4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin
|
Native Proteins
|
NP-KLH is a 4-Hydroxy-3-nitrophenylacetyl (NP) hapten. NP-KLH can be used for study as a carrier protein in immunological research .
|
-
- HY-W004649
-
|
Chelators
|
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
|
-
- HY-W402032
-
|
Chelators
|
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
|
-
- HY-144027
-
|
Drug Delivery
|
Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .
|
-
- HY-144008
-
|
Drug Delivery
|
C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
|
-
- HY-126393
-
|
Drug Delivery
|
Carboxymethyl-β-cyclodextrin, 99% is a cationic cyclodextrin used as a carrier for drugs. It has been shown to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity.
|
-
- HY-Y1903
-
|
Co-solvents
|
Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient .
|
-
- HY-144008A
-
|
Drug Delivery
|
C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
|
-
- HY-144004
-
DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
|
Drug Delivery
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-Y0873N
-
Polyethylene glycol 3000
|
Co-solvents
|
PEG3000 (Polyethylene glycol 3000) is a solvent for a large number of substances. PEG3000 can be used as a carrier material and modifying agent. PEG3000 is widely used in a variety of pharmaceutical formulations .
|
-
- HY-140740
-
|
Drug Delivery
|
DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-144011
-
|
Drug Delivery
|
DSPE-PEG-Cyanur is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur can be used for nanostructured lipid carrier .
|
-
- HY-W440916
-
|
Drug Delivery
|
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440915
-
|
Drug Delivery
|
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440917
-
|
Drug Delivery
|
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-D1005A11
-
PEG-PPG-PEG, 3400 (Averag)
|
Co-solvents
|
Poloxamer 185 P65 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 3400. Poloxamer 185 P65 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A12
-
PEG-PPG-PEG, 2750 (Averag)
|
Co-solvents
|
Poloxamer 212 L72 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2750. Poloxamer 212 L72 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A13
-
PEG-PPG-PEG, 4150 (Averag)
|
Co-solvents
|
Poloxamer 215 P75 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4150. Poloxamer 215 P75 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A15
-
PEG-PPG-PEG, 4200 (Averag)
|
Co-solvents
|
Poloxamer 234 P84 is is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4200. Poloxamer 234 P84 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A2
-
PEG-PPG-PEG, 1900 (Averag)
|
Co-solvents
|
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A20
-
PEG-PPG-PEG, 5900 (Averag)
|
Co-solvents
|
Poloxamer 334 P104 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 5900. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A5
-
PEG-PPG-PEG, 1850 (Averag)
|
Co-solvents
|
Poloxamer 123 L43 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1850. Poloxamer 123 L43 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-D1005A7
-
PEG-PPG-PEG, 2400 (Averag)
|
Co-solvents
|
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-151510
-
|
Drug Delivery
|
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .
|
-
- HY-W440928
-
|
Drug Delivery
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-128851A
-
|
Enzyme Substrates
|
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
|
-
- HY-128851B
-
|
Enzyme Substrates
|
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
|
-
- HY-W440815
-
|
Drug Delivery
|
6-((4-Hydroxybutyl)amino)hexyl 2-hexyldecanoate is a lipid, it can be used to synthesis nanomaterials. 6-((4-Hydroxybutyl)amino)hexyl provides the use of the nano-lipid particle as the key component in nucleic acid delivery, including the components of the delivery carrier .
|
-
- HY-144004A
-
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
- HY-144005
-
C16 PEG Ceramide (MW 2000)
|
Drug Delivery
|
C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research .
|
-
- HY-157914
-
6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane
|
Chelators
|
Dibenzyl-14-crown-4 (6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane) is a crown ether derivate, which serves as neutral carrier in PVC ion-selective electrode, improves the Li + selectivity against Na + and K + .
|
-
- HY-B1250
-
|
Biochemical Assay Reagents
|
Acedoben is a biochemical agent. Acedoben and iron ions can construct a fast self-assembled coordination complex. The Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties .
|
-
- HY-B1250A
-
|
Cell Assay Reagents
|
Acedoben sodium is the sodium salt form of Acedoben. Acedoben and iron ions can construct a rapidly self-assembled coordination complex, and the Fe-Ace coordination complex can not only serve as a carrier of tumor antigens, but also enhance antigen-specific anti-tumor immunity due to its inherent adjuvant properties .
|
-
- HY-Y0873M
-
Polyethylene glycol 500
|
Co-solvents
|
PEG500 (Polyethylene glycol 500) is a versatile polymer that's used as a solvent, dispersant, lubricant, and more in industries like pharmaceuticals and biotechnology, and it can also modify liposomes. PEG500 is commonly used as a solvent or carrier for drugs, helping with capsule endoscopy to improve image quality and cecum completion rates .
|
-
- HY-44134
-
Dimethyl α-ketoglutarate
|
Biochemical Assay Reagents
|
Dimethyl 2-oxoglutarate serves as a crucial intermediate in the Krebs cycle and an essential nitrogen carrier in metabolic pathways during biological processes. The electrochemical behavior of Dimethyl 2-oxoglutarate can be investigated using cyclic voltammetry, square wave voltammetry, and differential pulse voltammetry with a glassy carbon electrode .
|
-
- HY-147332
-
|
Drug Delivery
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
-
- HY-134421
-
|
Enzyme Substrates
|
2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ) .
|
-
- HY-CP001
-
|
Native Proteins
|
D-Trehalose is a disaccharide formed by a 1,1-glycosidic bond between two α-glucose units and is widely used as a food ingredient and pharmaceutical excipient. D-Trehalose is known to protect and stabilise proteins. For long-term storage, recombinant protein solution should be diluted further with 5% D-Trehalose, Carrier Protein.
|
-
- HY-155880
-
mPEG-NH2 (MW 350)
|
Drug Delivery
|
mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155881
-
mPEG-NH2 (MW 550)
|
Drug Delivery
|
mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155882
-
mPEG-NH2 (MW 750)
|
Drug Delivery
|
mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155883
-
mPEG-NH2 (MW 3400)
|
Drug Delivery
|
mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-D1005A17
-
PEG-PPG-PEG, 11400 (Averag)
|
Co-solvents
|
Poloxamer 238 F88 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 11400. Poloxamer 238 F88 reduces the aggregation of red blood cells. Poloxamer 238 F88 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
-
- HY-155884
-
mPEG-NH2 (MW 4000)
|
Drug Delivery
|
mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W115607
-
Poly(ethylene glycol)-bis-amine (MW 8000)
|
Drug Delivery
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
- HY-W591632
-
Poly(ethylene glycol)-bis-amine (MW 1000)
|
Drug Delivery
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
- HY-W440884
-
|
Drug Delivery
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
- HY-W440907
-
|
Drug Delivery
|
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.
|
- HY-CP002
-
|
Drug Delivery
|
Bovine Serum Albumin (BSA) is a 583 amino acid protein consisting of three homologous full alpha structural domains. BSA is a spherical protein essential for the transport of molecules such as fatty acids, drugs and hormones from the blood. It is used in many biochemical applications as a drug carrier for biologically active compounds. For long-term storage, recombinant protein solution should be diluted further with 0.1% BSA .
|
- HY-D1005A19
-
PEG-PPG-PEG, 4950 (Averag)
|
Co-solvents
|
Poloxamer 333 P103 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 4950. Poloxamer 333 P103 exhibits antimicrobial activity, that inihibits 90% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 333 P103 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-D1005A4
-
PEG-PPG-PEG, 1630 (Averag)
|
Co-solvents
|
Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-D1005A8
-
PEG-PPG-PEG, 2000 (Averag)
|
Co-solvents
|
Poloxamer 181 L61 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2000. Poloxamer 181 L61 exhibits antimicrobial activity, that inihibits 91% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 181 L61 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-D1005A9
-
PEG-PPG-PEG, 2650 (Averag)
|
Co-solvents
|
Poloxamer 183 L63 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2650. Poloxamer 183 L63 exhibits antimicrobial activity, that inihibits 83% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 183 L63 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-W440903
-
|
Drug Delivery
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
- HY-W440926
-
|
Drug Delivery
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
- HY-D1005A6
-
PEG-PPG-PEG, 2200 (Averag)
|
Co-solvents
|
Poloxamer 124 L44 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2200. Poloxamer 124 L44 reveals toxicity with an oral LD50 of 5 g/kg in albino rats. Poloxamer 124 L44 causes ocular irritation. Poloxamer 124 L44 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-D1005A21
-
PEG-PPG-PEG, 6500 (Averag)
|
Co-solvents
|
Poloxamer 335 P105 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 6500. Poloxamer 335 P105 exhibits antimicrobial activity, that inihibits 86% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 334 P104 exhibits muscular toxicity. Poloxamer 334 P104 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-137234
-
2,6-Di-O-methyl-β-cyclodextrin
|
Co-solvents
|
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
|
- HY-W588717
-
|
Biochemical Assay Reagents
|
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-Y1738
-
Tetrakis(triphenylphosphine)palladium(0)
|
Biochemical Assay Reagents
|
Tetrakis(triphenylphosphine)palladium (Pd(PPhs)) series of cross-coupling catalysts can be used to construct an organic heterojunction solar cell model. Adding different amounts of Pd(PPhs) significantly affected free carrier generation, non-twin trap and surface trap-assisted recombination as well as bimolecular recombination and charge extraction, but the impact on the non-duplex recombination process was limited because the catalyst could not promote efficient Trap-assisted reorganization. The studied system is highly robust with the addition of a small amount of Pd(PPha) .
|
- HY-D1005A10
-
PEG-PPG-PEG, 2900 (Averag)
|
Co-solvents
|
Poloxamer 184 L64 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2900. Poloxamer 184 L64 exhibts short-term dermal toxicity characterized by slight erythema and intradermal inflammatory response. Poloxamer 184 L64 exhibits antimicrobial activity, that inihibits 60% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 184 L64 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
|
- HY-137499
-
|
Drug Delivery
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
- HY-W011426
-
Propan-2-yl hexadecanoate
|
Drug Delivery
|
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1743
-
|
Peptides
|
Others
|
Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment .
|
-
- HY-P10128
-
|
Peptides
|
Inflammation/Immunology
|
GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .
|
-
- HY-P4104
-
|
Peptides
|
Others
|
pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide .
|
-
- HY-P4080
-
|
Peptides
|
Others
|
MPG peptides, Pα is an amphipathic carrier peptide that can be used for drug delivery .
|
-
- HY-P2120
-
|
Peptides
|
Others
|
Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
|
-
- HY-113736
-
|
Amino Acid Derivatives
|
Others
|
Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
|
-
- HY-P4205
-
|
Aminopeptidase
|
Cancer
|
Aminopeptidase N Ligand (CD13) NGR peptide is a polypeptide targeting CD13 and can be used as a carrier to mediate intracellular transmission. Aminopeptidase N Ligand (CD13) NGR peptide is often used in cancer research .
|
-
- HY-W587753
-
|
Antibiotic
Bacterial
|
Infection
|
Bacitracin A is an antibiotic, which exhibits antibacterial activity against gram-positive bacteria. Bacitracin A forms complex with long-chain polyisoprenyl pyrophosphates in presence of metal ions, dephosphorylates the lipid carrier intermediate Css-bactoprenyl pyrophosphate, inhibits thus the bacterial cell wall biosynthesis .
|
-
- HY-P10502
-
|
Peptides
|
Others
|
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery .
|
-
- HY-Y1091
-
|
Endogenous Metabolite
|
Others
|
D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance .
|
-
- HY-P4087
-
|
Peptides
|
Others
|
Cys(Npys)-(Arg)9 is a cell penetrating peptide. Cys(Npys)-(Arg)9 is comprised of 9 D-Arginine residues and an activated cysteine residue C(Npys). Cys(Npys)-(Arg)9 can be used as a carrier peptide applicable in conjugation and cell permable studies .
|
-
- HY-P6022
-
|
Peptides
|
Others
|
G4RGDSP, Integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. G4RGDSP, integrin-binding peptide is coupled to alginate to increase the viability of cells in the scaffold. G4RGDSP, integrin-binding peptide can be used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology
|
-
- HY-P5439
-
|
PKC
MARCKS
|
Others
|
Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N2522
-
-
-
- HY-N1502
-
-
-
- HY-128851
-
-
-
- HY-138962
-
-
-
- HY-126605
-
-
-
- HY-113400
-
-
-
- HY-W008940
-
-
-
- HY-N2522R
-
-
-
- HY-Y1091
-
-
-
- HY-W008940R
-
-
-
- HY-D0835
-
-
-
- HY-113003
-
-
-
- HY-N7103R
-
-
-
- HY-44134
-
-
-
- HY-134421
-
-
-
- HY-N7232
-
|
Structural Classification
Natural Products
Microorganisms
Source classification
|
Reverse Transcriptase
|
Limochromin is a pigment produced by Streptomyces limosus that strongly inhibits the reverse transcriptase of avian myeloid leukemia virus (AMV). The inhibitory activity of limochromin is not affected by changes in the concentration of template-primer, substrate or carrier protein, but its inhibitory effect is significantly reduced when the concentration of AMV reverse transcriptase increases. Limochromin can be used to develop antiviral treatments .
|
-
-
- HY-126304
-
-
-
- HY-D0886
-
-
-
- HY-154629
-
|
Classification of Application Fields
Disease Research Fields
Cancer
|
Biochemical Assay Reagents
|
Sesame Oil can be used as an excipient, such as Oil-soluble substance carrier, solvent, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
-
- HY-137499
-
-
-
- HY-B0445R
-
|
Structural Classification
Human Gut Microbiota Metabolites
Microorganisms
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Endogenous Metabolite
|
NAD+ (Standard) is the analytical standard of NAD+. This product is intended for research and analytical applications. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
In Vitro: NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH . NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) .
In Vivo: Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia .
|
-
-
- HY-W050154R
-
|
Structural Classification
Human Gut Microbiota Metabolites
Microorganisms
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Parasite
Tyrosinase
NF-κB
CDK
|
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113400S3
-
|
Cytidine diphosphate-d13 dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
-
- HY-113400S
-
|
Cytidine diphosphate- 15N3 dilithium is 15N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
-
- HY-113400S1
-
|
Cytidine diphosphate- 13C9 dilithium is 13C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
-
- HY-113400S2
-
|
Cytidine diphosphate- 13C9, 15N3 dilithium is 13C and 15N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-13728
-
ZD 9331; BGC9331
|
|
Alkynes
|
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W588717
-
|
|
DBCO
|
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-101532
-
β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin
|
|
Azide
|
6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin) is a new water-soluble Schiff base ligand based on β-cyclodextrin (HY-107201). 6a-Azido-6a-deoxy-β-cyclodextrin can be used for biaqueous hydroformylation. β-cyclodextrin (βCD) has a unique affinity for Dexamethasone (HY-14648), and can be used as a topical osmotic enhancer to introduce it into the agent carrier system . 6A-Azido-6A-deoxy-β-cyclodextrin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-164211
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DBCO
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DBCO-PEG2-OH is a functionalized polyethylene glycol (PEG) derivative that can be used to label azide-modified biomolecules spontaneously and as a component of drug carriers .
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Cat. No. |
Product Name |
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Classification |
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- HY-Y1888
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Corn oil
Maximum Cited Publications
65 Publications Verification
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Solvents
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Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
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- HY-144006
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14:0 PEG2000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
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Pegylated Lipids
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DMPE-PEG2000 (14:0 PEG2000 PE) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .
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- HY-W800782
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Cationic Lipids
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DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .
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- HY-159717
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Cationic Lipids
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Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .
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- HY-144027
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Polymers
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Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .
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- HY-113400
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Cytidine diphosphate
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Nucleotides and their Analogs
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Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
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- HY-W440698
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Pegylated Lipids
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Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
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- HY-159714
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Cationic Lipids
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Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA .
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- HY-159715
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Cationic Lipids
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Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA .
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- HY-159716
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Cationic Lipids
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Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .
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- HY-144008
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Pegylated Lipids
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C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
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- HY-144008A
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Pegylated Lipids
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C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
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- HY-144004
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DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
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Pegylated Lipids
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-N7103
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Solvents
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Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration .
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- HY-140740
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Pegylated Lipids
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DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
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- HY-144011
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Pegylated Lipids
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DSPE-PEG-Cyanur is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur can be used for nanostructured lipid carrier .
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- HY-W440916
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440915
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440917
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-151510
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Cationic Lipids
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A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .
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- HY-144004A
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DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
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Pegylated Lipids
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DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
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- HY-144005
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C16 PEG Ceramide (MW 2000)
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Pegylated Lipids
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C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research .
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- HY-W339838
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14:0 Lyso PG
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Phospholipids
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1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-147332
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Cationic Lipids
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TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
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- HY-155880
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mPEG-NH2 (MW 350)
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Polymers
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mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-155881
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mPEG-NH2 (MW 550)
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Polymers
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mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-155882
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mPEG-NH2 (MW 750)
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Polymers
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mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-155883
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mPEG-NH2 (MW 3400)
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Polymers
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mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-145505
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18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol
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Phospholipids
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1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-155884
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mPEG-NH2 (MW 4000)
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Polymers
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mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-W115607
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Poly(ethylene glycol)-bis-amine (MW 8000)
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Polymers
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PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-W591632
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Poly(ethylene glycol)-bis-amine (MW 1000)
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Polymers
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PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
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- HY-145506
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18:0 Lyso PG sodium
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Phospholipids
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1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-145507
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)
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Phospholipids
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-B2247A
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poly(lactic-co-glycolic acid) (75:25)
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Polymers
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PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
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- HY-154629
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Solvents
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Sesame Oil can be used as an excipient, such as Oil-soluble substance carrier, solvent, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-137499
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Cationic Lipids
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NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
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- HY-147081
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AGRO-100
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Aptamers
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AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
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- HY-W011426
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Propan-2-yl hexadecanoate
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Solvents
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Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-159751
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Adjuvant
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HS101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159752
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Adjuvant
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HS103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159753
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Adjuvant
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HS105 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159754
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Adjuvant
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HS201 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159746
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Adjuvant
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HS801 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159743
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Adjuvant
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M101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159744
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Adjuvant
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M103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159745
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Adjuvant
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M107 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159747
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Adjuvant
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M401 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159748
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Adjuvant
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M402 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159749
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Adjuvant
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M902 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159750
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Adjuvant
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M903 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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