2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Adrenergic Receptor Endogenous Metabolite
  4. Tamsulosin hydrochloride

Tamsulosin hydrochloride  (Synonyms: (R)-(-)-YM12617; LY253351)

Cat. No.: HY-B0661A Purity: 99.81%
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Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models.

For research use only. We do not sell to patients.

Tamsulosin hydrochloride Chemical Structure

Tamsulosin hydrochloride Chemical Structure

CAS No. : 106463-17-6

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10 mg USD 37 In-stock
25 mg USD 60 In-stock
50 mg USD 85 In-stock
100 mg USD 120 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Tamsulosin hydrochloride:

Tamsulosin hydrochloride Related Antibodies

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α adrenergic receptor β adrenergic receptor

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Description

Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models[1].

IC50 & Target[1]

α1-adrenergic receptor

 

Clinical Trial
Molecular Weight

444.97

Formula

C20H29ClN2O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC(C[C@H](NCCOC2=CC=CC=C2OCC)C)=CC=C1OC)(N)=O.Cl
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (140.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2473 mL 11.2367 mL 22.4734 mL
5 mM 0.4495 mL 2.2473 mL 4.4947 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2473 mL 11.2367 mL 22.4734 mL 56.1836 mL
5 mM 0.4495 mL 2.2473 mL 4.4947 mL 11.2367 mL
10 mM 0.2247 mL 1.1237 mL 2.2473 mL 5.6184 mL
15 mM 0.1498 mL 0.7491 mL 1.4982 mL 3.7456 mL
20 mM 0.1124 mL 0.5618 mL 1.1237 mL 2.8092 mL
25 mM 0.0899 mL 0.4495 mL 0.8989 mL 2.2473 mL
30 mM 0.0749 mL 0.3746 mL 0.7491 mL 1.8728 mL
40 mM 0.0562 mL 0.2809 mL 0.5618 mL 1.4046 mL
50 mM 0.0449 mL 0.2247 mL 0.4495 mL 1.1237 mL
60 mM 0.0375 mL 0.1873 mL 0.3746 mL 0.9364 mL
80 mM 0.0281 mL 0.1405 mL 0.2809 mL 0.7023 mL
100 mM 0.0225 mL 0.1124 mL 0.2247 mL 0.5618 mL
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Tamsulosin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tamsulosin106463-17-6(R)-(-)-YM12617 LY253351LY253351LY 253351LY-253351Adrenergic ReceptorEndogenous MetaboliteBeta ReceptorInhibitorinhibitorinhibit

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