L-Lactic acid (Synonyms: (S)-2-Hydroxypropanoic acid)

Name: L-Lactic acid
Brand: MedChemExpress
SKU: HY-Y0479
Rating: 5.0 (5 reviews)

Cat. No.: HY-Y0479 Purity: 98.18%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

For research use only. We do not sell to patients.

L-Lactic acid Chemical Structure

CAS No. : 79-33-4

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
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Based on 5 publication(s) in Google Scholar

Other Forms of L-Lactic acid:

L-Lactic acid-¹³C₃ Get quote
L-Lactic acid-2-¹³C₁ Get quote
L-Lactic acid lithium Get quote
Sodium (S)-2-hydroxypropanoate Get quote
Sodium (S)-2-hydroxypropanoate (purity≥90%) Get quote
L-Lactic acid (Standard) Get quote

5 Publications Citing Use of MCE L-Lactic acid

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Biological Activity
Purity & Documentation
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Description

L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	26.6 μM Compound: Lactic acid	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28710964]
MRC5	IC₅₀	23.93 μM Compound: Lactic acid	Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay	[PMID: 28710964]

Clinical Trial

Molecular Weight

90.08

Formula

C₃H₆O₃

CAS No.

79-33-4

Appearance

<53°C Solid,>53°C Liquid

Color

Colorless to off-white

SMILES

C[C@H](O)C(O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (1110.15 mM; Need ultrasonic)

DMSO : 100 mg/mL (1110.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	11.1015 mL	55.5074 mL	111.0149 mL
5 mM	2.2203 mL	11.1015 mL	22.2030 mL
10 mM	1.1101 mL	5.5507 mL	11.1015 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (23.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (23.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 3

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (23.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 4

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (23.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 5

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (23.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.27%

Select Batch:

Data Sheet (248 KB) SDS (476 KB)

COA (250 KB) HNMR (228 KB) LCMS (256 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	11.1015 mL	55.5074 mL	111.0149 mL	277.5372 mL
	5 mM	2.2203 mL	11.1015 mL	22.2030 mL	55.5074 mL
	10 mM	1.1101 mL	5.5507 mL	11.1015 mL	27.7537 mL
	15 mM	0.7401 mL	3.7005 mL	7.4010 mL	18.5025 mL
	20 mM	0.5551 mL	2.7754 mL	5.5507 mL	13.8769 mL
	25 mM	0.4441 mL	2.2203 mL	4.4406 mL	11.1015 mL
	30 mM	0.3700 mL	1.8502 mL	3.7005 mL	9.2512 mL
	40 mM	0.2775 mL	1.3877 mL	2.7754 mL	6.9384 mL
	50 mM	0.2220 mL	1.1101 mL	2.2203 mL	5.5507 mL
	60 mM	0.1850 mL	0.9251 mL	1.8502 mL	4.6256 mL
	80 mM	0.1388 mL	0.6938 mL	1.3877 mL	3.4692 mL
	100 mM	0.1110 mL	0.5551 mL	1.1101 mL	2.7754 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

L-Lactic acid Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Lactic acid79-33-4(S)-2-Hydroxypropanoic acidBacterialEndogenous MetaboliteAntibioticInhibitorinhibitorinhibit

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L-Lactic acid (Synonyms: (S)-2-Hydroxypropanoic acid)

Customer Review

Other Forms of L-Lactic acid:

L-Lactic acid Related Antibodies

5 Publications Citing Use of MCE L-Lactic acid

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Antibiotic Isoform Specific Products:

Biological Activity

Purity & Documentation

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

L-Lactic acid Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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