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  4. Denosumab

Denosumab  (Synonyms: Immunoglobulin G2; Ranmark)

Cat. No.: HY-P9958 Purity: 99.10%
SDS COA

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Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures, also has anti-cancer activity.

For research use only. We do not sell to patients.

CAS No. : 615258-40-7

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10 mg USD 1040 In-stock
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Based on 1 publication(s) in Google Scholar

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Denosumab Related Antibodies

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1 Publications Citing Use of MCE Denosumab

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Description

Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].

Isotype

Human IgG2 kappa
Recommend Isotype Controls
Species

Human
Clinical Trial
Molecular Weight

144716.86

Formula

C6404H9908N1724O2004S50
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Denosumab]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG2 kappa
Purity & Documentation

Purity: 99.10%

SDS (251 KB)

COA (232 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Denosumab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Denosumab615258-40-7Immunoglobulin G2 RanmarkImmunoglobulin G 2Immunoglobulin G-2NF-κBNuclear factor-κBNuclear factor-kappaBRANKLOsteoporosisCancerInhibitorinhibitorinhibit

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