Arntl - aryl hydrocarbon receptor nuclear translocator-like Gene

Mus musculus

Also known as MOP3; Arnt3; Bmal1; BMAL1b; bHLHe5; bmal1b'

Gene ID: 11865 | Gene type: protein coding

About Arntl

Summary

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]

Arntl Products(11)

mRNA	Protein	Name
NM_001243048.2	NP_001229977.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 2
NM_001357070.2	NP_001343999.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 3
NM_001368412.1	NP_001355341.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 4
NM_001374642.1	NP_001361571.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 5
NM_001411976.1	NP_001398905.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 6
NM_001411977.1	NP_001398906.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 5
NM_001411978.1	NP_001398907.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 7
NM_001411979.1	NP_001398908.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 1
NM_001411980.1	NP_001398909.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 1
NM_001411981.1	NP_001398910.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 3
NM_007489.5	NP_031515.1	aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 1

Protein Preferred Names

Protein Names

aryl hydrocarbon receptor nuclear translocator-like protein 1

brain and muscle ARNT-like 1

Arntl Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Bmal1	Q9WTL8	CIART	Homo sapiens	Q8N365	Anti Tag CoIP	24737000
Cross	Bmal1	Q9WTL8	CIART	Homo sapiens	Q8N365	Y2H	24737000
Cross	Bmal1	Q9WTL8	CIART	Homo sapiens	Q8N365	BiFC	24737000
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Bait CoIP	20832105
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Bait CoIP	26562092
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Tag CoIP	16777965
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Tag CoIP	26562092
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Tag CoIP	18430226
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Pull Down	26562092
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Y2H	23555304
Intra	Bmal1	Q9WTL8	Cry1	Mus musculus	P97784	Anti Tag CoIP	23555304
Intra	Bmal1	Q9WTL8	Cry2	Mus musculus	Q9R194	Y2H	23555304
Intra	Bmal1	Q9WTL8	Cry2	Mus musculus	Q9R194	Y2H	20840750
Intra	Bmal1	Q9WTL8	Cry2	Mus musculus	Q9R194	Anti Bait CoIP	20832105
Intra	Bmal1	Q9WTL8	Cry2	Mus musculus	Q9R194	Anti Bait CoIP	26562092
Intra	Bmal1	Q9WTL8	Cry2	Mus musculus	Q9R194	Anti Tag CoIP	26562092
Intra	Bmal1	Q9WTL8	Per2	Mus musculus	O54943	Gal4 VP16 Complement	18430226
Intra	Bmal1	Q9WTL8	Per2	Mus musculus	O54943	Anti Bait CoIP	20832105
Intra	Bmal1	Q9WTL8	Per2	Mus musculus	O54943	Anti Tag CoIP	16777965
Cross	Bmal1	Q9WTL8	CSNK2B	Homo sapiens	P67870	Pull Down	26562092
Cross	Bmal1	Q9WTL8	CSNK2B	Homo sapiens	P67870	SLC	26562092
Cross	Bmal1	Q9WTL8	CSNK2B	Homo sapiens	P67870	Y2H	23555304
Intra	Bmal1	Q9WTL8	Csnk2b	Mus musculus	P67871	Anti Bait CoIP	26562092
Cross	Bmal1	Q9WTL8	RORC	Homo sapiens	P51449	Y2H	23555304
Cross	Bmal1	Q9WTL8	RORC	Homo sapiens	P51449	Anti Tag CoIP	23555304
Cross	Bmal1	Q9WTL8	WDR5	Homo sapiens	P61964	Anti Tag CoIP	23555304
Intra	Bmal1	Q9WTL8	Parp1	Mus musculus	P11103	Anti Bait CoIP	20832105
Intra	Bmal1	Q9WTL8	Csnk2a1	Mus musculus	Q60737	Anti Bait CoIP	26562092
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Tag CoIP	26562092
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	22441692
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	BiFC	24737000
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	18662546
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	20832105
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Y2H	23555304
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	18075593
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	17347670
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	28388406
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Y2H Array	20211142
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Bait CoIP	18662547
Intra	Bmal1	Q9WTL8	Clock	Mus musculus	O08785	Anti Tag CoIP	16606840

Cross: Cross-species interaction Intra: Intraspecies interaction

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