2. Gene
  3. Hmgb1 - high mobility group box 1 Gene

Hmgb1 - high mobility group box 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p30; Hmg1; HMG-1; SBP-1

Gene ID: 15289 | Gene type: protein coding

About Hmgb1

Summary

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

Hmgb1 Products(2)

mRNA Protein Name
NM_001313894.1 NP_001300823.1 high mobility group protein B1
NM_010439.4 NP_034569.1 high mobility group protein B1
Protein Preferred Names Protein Names

high mobility group protein B1

amphoterin

high mobility group protein 1

Recombinant Hmgb1 Proteins

Cat. No. Product Name Accession Purity
HY-P73104 HMGB1/HMG-1 Protein, Mouse (HEK293, Fc, solution) P63158 (M1-E215) ≥95%
HY-P73104A HMGB1/HMG-1 Protein, Mouse (HEK293, Fc) P63158 (M1-E215) ≥95%
HY-P700182AF Animal-Free HMGB1/HMG-1 Protein, Mouse (His) P63158 (M1-E215) ≥95%

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0184 Glycyrrhizic acid Inhibitor 99.65% Yes
HY-N0184A Dipotassium glycyrrhizinate Inhibitor 99.68% Yes
HY-N0184R Glycyrrhizic acid (Standard) Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-Y1362 Ethyl pyruvate 99.87% Phase 4
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101872 GSK-872 Inhibitor 99.91% Unkown
HY-101872A GSK-872 hydrochloride Inhibitor 99.21% Unkown
HY-111815A N4-Acetylcytidine triphosphate sodium 99.43% Unkown
HY-113772 Inflachromene 99.88% Unkown
HY-P2268A RAGE antagonist peptide TFA Antagonist 99.71% Unkown
HY-124750 NecroX-7 Inhibitor 99.69% Unkown
HY-P2268 RAGE antagonist peptide Antagonist 98.53% Unkown
HY-148226 20-5,14-HEDGE 98.74% Unkown
HY-N2055 Kaempferol 3-O-sophoroside 99.84% Unkown
HY-155751 HMGB1-IN-1 Inhibitor 99.37% Unkown
HY-111815 N4-Acetylcytidine triphosphate / Unkown
HY-143456 Anti-inflammatory agent 18 Inhibitor / Unkown
HY-143457 Anti-inflammatory agent 19 Inhibitor / Unkown
HY-155759 HMGB1-IN-2 Inhibitor / Unkown
HY-163409 CGK012 Inhibitor / Unkown
HY-168053 HMGB1-IN-3 / Unkown
HY-N9587 Tricin 7-O-β-D-glucopyranoside Inducer / Unkown
HY-RS06232 HMGB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-19421 Orazamide / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmgb1 NCBI NCBI:3146