2. Gene
  3. TRIM29 - tripartite motif containing 29 Gene

TRIM29 - tripartite motif containing 29 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ATDC

Gene ID: 23650 | Gene type: protein coding

About TRIM29

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:120,111,286-120,138,113 (from NCBI)

This gene has 21 transcripts (splice variants), 118 orthologues and 80 paralogues. Biased expression in esophagus (RPKM 274.4), skin (RPKM 264.0) and 4 other tissues.

Summary

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]

TRIM29 Products(2)

mRNA Protein Name
NM_001330382.2 NP_001317311.1 tripartite motif-containing protein 29 isoform 2
NM_012101.4 NP_036233.2 tripartite motif-containing protein 29 isoform 1

TRIM29 Protein Structure

zf-B_box

zf-B_box: B-box zinc finger (221 - 260)

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  • 588 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 29

ataxia-telangiectasia group D-associated protein

Related Diseases

Diseases Alias
Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128481 SB24011 Activator / Unkown
HY-RS15034 TRIM29 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TRIM29 VGNC VGNC:36325
Mus musculus TRIM29 MGD MGI:1919419
Felis catus TRIM29 VGNC VGNC:66532
Rattus norvegicus TRIM29 RGD RGD:1307858
Macaca mulatta TRIM29 VGNC VGNC:79069
Canis familiaris TRIM29 VGNC VGNC:47812