2. Gene
  3. Hdac10 - histone deacetylase 10 Gene

Hdac10 - histone deacetylase 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362981 | Gene type: protein coding

About Hdac10

Primary_assembly 7: 120,199,129-120,204,228 reverse strand.mRatBN7.2:CM026980.1

This gene has 3 transcripts (splice variants), 181 orthologues, 12 paralogues and is associated with 4 phenotypes. Biased expression in Muscle (RPKM 36.9), Thymus (RPKM 35.1) and 9 other tissues.

Summary

Predicted to enable histone deacetylase activity; histone deacetylase binding activity; and zinc ion binding activity. Involved in oligodendrocyte development. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC10 (histone deacetylase 10). [provided by Alliance of Genome Resources, Apr 2022]

Hdac10 Products(1)

mRNA Protein Name
NM_001035000.1 NP_001030172.1 polyamine deacetylase HDAC10
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in oligodendrocyte development IEP
IEP: Inferred from expression pattern
18627006 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Hdac10 Protein Structure

Arginase_HDAC

Arginase_HDAC: cl17011 (17 - 353)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
Protein Preferred Names Protein Names

polyamine deacetylase HDAC10

HD10

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109015 Tucidinostat Inhibitor 98.70% Unkown
HY-13322 Pracinostat Inhibitor 99.82% Yes
HY-B0494 Bufexamac Inhibitor ≥98.0% Unkown
Clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-10990 Abexinostat Inhibitor 98.63% Phase 3
HY-14842 Givinostat Inhibitor 98.16% Phase 3
HY-14842B Givinostat hydrochloride monohydrate Inhibitor ≥98.0% Phase 3
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Phase 3
HY-15433 Quisinostat Inhibitor 98.34% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 98.28% Phase 2
HY-16012A Domatinostat Inhibitor 99.43% Phase 2
HY-101780 Tinostamustine Inhibitor 99.42% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2
HY-10223 CUDC-101 Inhibitor 98.84% Phase 1
Pre-clinical Phase
Bioactive Molecules (31)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13428 Tubacin Inhibitor 99.54% Unkown
HY-15224 PCI-34051 Inhibitor 99.75% Unkown
HY-18613 CAY10603 Inhibitor ≥98.0% Unkown
HY-16699 Nexturastat A Inhibitor 98.28% Unkown
HY-111818 TH34 Inhibitor 99.52% Unkown
HY-115475 SW-100 Inhibitor 99.59% Unkown
HY-144779 HDAC10-IN-1 Inhibitor 99.11% Unkown
HY-19747 HPOB Inhibitor 99.80% Unkown
HY-110280 MC1742 Inhibitor 99.20% Unkown
HY-152174 HDAC-IN-52 Inhibitor 99.46% Unkown
HY-150109 Purinostat mesylate Inhibitor / Unkown
HY-147731 HDAC6-IN-9 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-109015S Tucidinostat-d4 Inhibitor / Unkown
HY-157740 XSJ-10 Inhibitor / Unkown
HY-19754A CRA-026440 hydrochloride Inhibitor 98.14% Unkown
HY-152226 MC2590 Inhibitor / Unkown
HY-144782 HDAC10-IN-2 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-163834 HDAC6-IN-47 Inhibitor / Unkown
HY-163430 HDAC-IN-71 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-152173 HDAC-IN-51 Inhibitor / Unkown
HY-147966 HDAC-IN-43 Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-162658 Leuxinostat Inhibitor / Unkown
HY-19754 CRA-026440 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdac10 NCBI NCBI:83933