2. Gene
  3. CYB5B - cytochrome b5 type B Gene

CYB5B - cytochrome b5 type B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as OMB5; CYB5-M; CYPB5M

Gene ID: 80777 | Gene type: protein coding

About CYB5B

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:69,424,619-69,466,264 (from NCBI)

This gene has 17 transcripts (splice variants), 224 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 70.4), colon (RPKM 17.6) and 22 other tissues.

Summary

Enables heme binding activity. Contributes to nitrite reductase (NO-forming) activity. Involved in nitric oxide biosynthetic process. Located in membrane. Part of nitric-oxide synthase complex. [provided by Alliance of Genome Resources, Apr 2022]

CYB5B Products(1)

mRNA Protein Name
NM_030579.3 NP_085056.2 cytochrome b5 type B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heme binding IDA
IDA: Inferred from direct assay
20861021 GOA
contributes to nitrite reductase (NO-forming) activity IDA
IDA: Inferred from direct assay
24500710 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25616068 GOA
Biological Process GO Annotation Evidence Reference Source
involved in nitric oxide biosynthetic process IDA
IDA: Inferred from direct assay
24500710 GOA
Cellular Component GO Annotation Evidence Reference Source
part of nitric-oxide synthase complex IDA
IDA: Inferred from direct assay
24500710 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYB5B Protein Structure

Cyt-b5

Cyt-b5: Cytochrome b5-like Heme/Steroid binding domain (22 - 95)

  • 0
  • 100
  • 146 a.a.
Protein Preferred Names Protein Names

cytochrome b5 type B

cytochrome b5 type B (outer mitochondrial membrane)

Recombinant CYB5B Proteins

Cat. No. Product Name Accession Purity
HY-P70136 CYB5B Protein, Human (HEK293, His) AAH04373.1 (K12-C118) ≥95%

Related Diseases

Diseases Alias
Angular Cheilitis

Cheilosis

Angular Cheilosis

Angular Stomatitis

Commissural Cheilitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03418 CYB5B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CYB5B MGD MGI:1913677
Bos taurus CYB5B VGNC VGNC:49139
Rattus norvegicus CYB5B RGD RGD:621551
Macaca mulatta CYB5B VGNC VGNC:96713
Others CYB5B NCBI