2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Indoramin

Indoramin  (Synonyms: Indoramine; Wy 21901)

Cat. No.: HY-12760 Purity: 99.80%
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Indoramin is an orally active antihypertensive agent. Indoramin is also selective for the α1A-adrenoceptor.

For research use only. We do not sell to patients.

Indoramin Chemical Structure

Indoramin Chemical Structure

CAS No. : 26844-12-2

Size Price Stock Quantity
1 mg USD 86 In-stock
5 mg USD 190 In-stock
10 mg USD 304 In-stock
25 mg USD 609 In-stock
50 mg USD 975 In-stock
100 mg USD 1560 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Indoramin:

Indoramin Related Antibodies

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α adrenergic receptor β adrenergic receptor

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Description

Indoramin is an orally active antihypertensive agent. Indoramin is also selective for the α1A-adrenoceptor[1].

Molecular Weight

347.45

Formula

C22H25N3O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC1CCN(CCC2=CNC3=C2C=CC=C3)CC1)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 7.69 mg/mL (22.13 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8781 mL 14.3906 mL 28.7811 mL
5 mM 0.5756 mL 2.8781 mL 5.7562 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  50% PEG300    50% Saline

    Solubility: 10 mg/mL (28.78 mM); Suspended solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8781 mL 14.3906 mL 28.7811 mL 71.9528 mL
5 mM 0.5756 mL 2.8781 mL 5.7562 mL 14.3906 mL
10 mM 0.2878 mL 1.4391 mL 2.8781 mL 7.1953 mL
15 mM 0.1919 mL 0.9594 mL 1.9187 mL 4.7969 mL
20 mM 0.1439 mL 0.7195 mL 1.4391 mL 3.5976 mL
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Indoramin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Indoramin26844-12-2Indoramine Wy 21901Wy21901Wy 21901Wy-21901Adrenergic ReceptorBeta ReceptorantihypertensiveadrenoceptorInhibitorinhibitorinhibit

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