2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Lipopolysaccharides, from Proteus vulgaris

Lipopolysaccharides, from Proteus vulgaris  (Synonyms: LPS, from bacterial (Proteus vulgaris))

Cat. No.: HY-D1056B1
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Lipopolysaccharides, from Proteus vulgaris are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus vulgaris, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus vulgaris exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Proteus vulgaris possess a unique molecular structure and chitosan affinity (Kb=2.72 μM), surpassing that of Yersinia pseudotuberculosis (Kb=6.06 μM) and Escherichia coli (Kb=79.50 μM).

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Lipopolysaccharides, from Proteus vulgaris Chemical Structure

Lipopolysaccharides, from Proteus vulgaris Chemical Structure

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Lipopolysaccharides, from Proteus vulgaris Related Antibodies

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Description

Lipopolysaccharides, from Proteus vulgaris are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus vulgaris, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus vulgaris exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Proteus vulgaris possess a unique molecular structure and chitosan affinity (Kb=2.72 μM), surpassing that of Yersinia pseudotuberculosis (Kb=6.06 μM) and Escherichia coli (Kb=79.50 μM)[1].

IC50 & Target

TLR-4[2]
In Vitro

Note:
To maintain the integrity of LPS, it is recommended to store LPS solution in silanized containers. This is because LPS can adhere to plastics and certain types of glass, particularly at concentrations below 0.1 mg/mL. If the LPS concentration exceeds 1 mg/mL, this adsorption effect is relatively minimal. If using glass containers, ensure that the solution is thoroughly mixed for at least 30 minutes before use to redissolve any LPS that may have adsorbed to the tube walls.

Lipopolysaccharides, from Proteus vulgaris (200 μg/mL; 2 h) form complexes with high particle size distribution and polydispersity after incubation with chitosan[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lipopolysaccharides, from Proteus vulgaris Related Antibodies
SMILES

[Lipopolysaccharides, from Proteus vulgaris]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Lipopolysaccharides, from Proteus vulgaris Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lipopolysaccharides, from Proteus vulgarisLPS, from bacterial (Proteus vulgaris)Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

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