Olmutinib hydrochloride (Synonyms: HM61713 hydrochloride; BI 1482694 hydrochloride)

Cat. No.: HY-19730A: Data Sheet Handling Instructions Technical Support

Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC.

For research use only. We do not sell to patients.

Olmutinib hydrochloride Chemical Structure

CAS No. : 1842366-97-5

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

* Please select Quantity before adding items.

Other In-stock Forms of Olmutinib hydrochloride:

Olmutinib

Other Forms of Olmutinib hydrochloride:

Olmutinib In-stock

9 Publications Citing Use of MCE Olmutinib hydrochloride

: Olmutinib hydrochloride purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2018 Jul;8(4):563-574. [Abstract]; The protein levels of ABCG2 in MDR cells after different concentrations Olmutinib stimulation for 48 h are measured by Western blot analysis (GAPDH as loading control).

Featured Recommendations

•Related Small Molecules:

View All EGFR Isoform Specific Products:

View All Isoforms

EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

Biological Activity
Purity & Documentation
References
Customer Review

Description	Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC^[1]^[2].
Molecular Weight	559.51
Formula	C₂₆H₂₈Cl₂N₆O₂S
CAS No.	1842366-97-5
SMILES	O=C(NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C=C3)=NC5=C2SC=C5)=CC=C1)C=C.Cl.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Kim ES, et al. Olmutinib: First Global Approval. Drugs. 2016 Jul;76(11):1153-7. [Content Brief] [2]. Mohamed W. Attwa, et al. Detection and characterization of olmutinib reactive metabolites by LC‐MS/MS: Elucidation of bioactivation pathways. Journal of Separation science. 18 November 2019.

Olmutinib hydrochloride Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Keywords:

Olmutinib1842366-97-5HM61713BI 1482694HM 61713HM-61713BI1482694BI-1482694EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Olmutinib hydrochloride (Synonyms: HM61713 hydrochloride; BI 1482694 hydrochloride)

Other Forms of Olmutinib hydrochloride:

Olmutinib hydrochloride Related Antibodies

9 Publications Citing Use of MCE Olmutinib hydrochloride

Featured Recommendations

•Related Small Molecules:

View All EGFR Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

Olmutinib hydrochloride Related Classifications

Molarity Calculator

Dilution Calculator