2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Olmutinib hydrochloride

Olmutinib hydrochloride  (Synonyms: HM61713 hydrochloride; BI 1482694 hydrochloride)

Cat. No.: HY-19730A
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Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC.

For research use only. We do not sell to patients.

Olmutinib hydrochloride Chemical Structure

Olmutinib hydrochloride Chemical Structure

CAS No. : 1842366-97-5

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Olmutinib hydrochloride Related Antibodies

Top Publications Citing Use of Products

    Olmutinib hydrochloride purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2018 Jul;8(4):563-574.  [Abstract]

    The protein levels of ABCG2 in MDR cells after different concentrations Olmutinib stimulation for 48 h are measured by Western blot analysis (GAPDH as loading control).

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    Description

    Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC[1][2].

    Molecular Weight

    559.51

    Formula

    C26H28Cl2N6O2S
    CAS No.
    SMILES

    O=C(NC1=CC(OC2=NC(NC3=CC=C(N4CCN(CC4)C)C=C3)=NC5=C2SC=C5)=CC=C1)C=C.Cl.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Olmutinib hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Olmutinib1842366-97-5HM61713BI 1482694HM 61713HM-61713BI1482694BI-1482694EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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