2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. Polyphemusin II-Derived Peptide

Polyphemusin II-Derived Peptide  (Synonyms: T140)

Cat. No.: HY-P4810
Data Sheet Handling Instructions Technical Support

Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4.

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Polyphemusin II-Derived Peptide Chemical Structure

Polyphemusin II-Derived Peptide Chemical Structure

CAS No. : 229030-20-0

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Polyphemusin II-Derived Peptide Related Antibodies

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Description

Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4[1].

Molecular Weight

2037.42

Formula

C90H141N33O18S2
CAS No.
Sequence

Arg-Arg-2-Nal-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg (Disulfide bridge:Cys4-Cys13)
Sequence Shortening

RRACYRKKPYR-{Cit}-CR (Disulfide bridge:Cys4-Cys13)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Polyphemusin II-Derived Peptide Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Polyphemusin II-Derived Peptide229030-20-0T140T 140T-140CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsHIVCXCR4CCR5Inhibitorinhibitorinhibit

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