2. Anti-infection Immunology/Inflammation
  3. SARS-CoV Virus Protease NO Synthase
  4. SARS-CoV-2-IN-107

SARS-CoV-2-IN-107 (Compound A7) is the inhibitor for SARS-CoV-2 3CLpro with an IC50 of 261.3 nM. SARS-CoV-2-IN-107 inhibits the SARS-CoV-2 replication with an EC50 of 11.7 μM. SARS-CoV-2-IN-107 exhibits anti-inflammatory activity with a NO inhibition rate of 68.6% in LPS (HY-D1056)-stimulated RAW264.7 macrophages.

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SARS-CoV-2-IN-107 Chemical Structure

SARS-CoV-2-IN-107 Chemical Structure

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SARS-CoV-2-IN-107 Related Antibodies

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Description

SARS-CoV-2-IN-107 (Compound A7) is the inhibitor for SARS-CoV-2 3CLpro with an IC50 of 261.3 nM. SARS-CoV-2-IN-107 inhibits the SARS-CoV-2 replication with an EC50 of 11.7 μM. SARS-CoV-2-IN-107 exhibits anti-inflammatory activity with a NO inhibition rate of 68.6% in LPS (HY-D1056)-stimulated RAW264.7 macrophages[1].

Molecular Weight

274.24

Formula

C15H11FO4
SMILES

O=C(C1=CC=C(F)C=C1)/C=C/C2=CC(O)=C(O)C(O)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV-2-IN-107 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2-IN-107SARS-CoVVirus ProteaseNO SynthaseSARS coronavirusNitric oxide synthasesNOSRAW264.7dualanti-inflammatoryInhibitorinhibitorinhibit

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