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2'-Deoxyuridine-d

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11

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28

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0186S7

    Endogenous Metabolite Infection
    2'-Deoxyuridine- 13C, 15N2 is the 13C and 15N labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
    2'-Deoxyuridine-13C,15N2
  • HY-W012282

    Antibiotic Infection Cancer
    3′-Deoxyuridine is a potential anticancer and antiviral agent. 3'-deoxyuridine inhibits bovine diarrhoea virus (BVDV) production .
    3′-Deoxyuridine
  • HY-D0186S5

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]<
    2'-Deoxyuridine-d
  • HY-D0186S4

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-d2 is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
    2'-Deoxyuridine-d2
  • HY-D0186S8

    Endogenous Metabolite Infection
    2'-Deoxyuridine-d2-1 is the deuterium labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
    2'-Deoxyuridine-d2-1
  • HY-D0186S

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-1′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
    2'-Deoxyuridine-1′-13C
  • HY-D0186S1

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-2′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
    2'-Deoxyuridine-2′-13C
  • HY-D0186S2

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-3′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
    2'-Deoxyuridine-3′-13C
  • HY-D0186S3

    Isotope-Labeled Compounds Endogenous Metabolite Infection
    2'-Deoxyuridine-5′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
    2'-Deoxyuridine-5′-13C
  • HY-D0186R

    Endogenous Metabolite Thymidylate Synthase Infection
    2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine .
    Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min .
    In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain .
    2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .
    2'-Deoxyuridine (Standard)
  • HY-W424779R

    Drug Metabolite Infection
    5-Carboxy-2′-deoxyuridine (Standard) is the analytical standard of 5-Carboxy-2′-deoxyuridine. This product is intended for research and analytical applications. 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .
    5-Carboxy-2′-deoxyuridine (Standard)
  • HY-D0186
    2'-Deoxyuridine
    1 Publications Verification

    Endogenous Metabolite Thymidylate Synthase Infection
    2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .
    2'-Deoxyuridine
  • HY-129983

    HSV Infection Cancer
    5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia .
    5-Hydroxymethyl-2'-deoxyuridine
  • HY-W424779

    Drug Metabolite Infection
    5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .
    5-Carboxy-2′-deoxyuridine
  • HY-130801

    5-OHdU

    Endogenous Metabolite Metabolic Disease
    5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .
    5-Hydroxy-2'-deoxyuridine
  • HY-W341499

    Endogenous Metabolite Others
    5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .
    5-Formyl-2'-deoxyuridine
  • HY-135780

    3'-dUTP

    Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite Metabolic Disease
    3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM .
    3'-Deoxyuridine-5'-triphosphate
  • HY-135957

    N3dUrd

    DNA/RNA Synthesis Cancer
    2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity . 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    2'-Azido-2'-deoxyuridine
  • HY-135780A

    3'-dUTP trisodium

    Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite Metabolic Disease
    3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM .
    3'-Deoxyuridine-5'-triphosphate trisodium
  • HY-W190976

    5-VINYL-DURD

    DNA/RNA Synthesis Apoptosis Cancer
    5-Vinyl-2'-deoxyuridine (5-VINYL-DURD), a thymidine analogue, is incorporated into cellular DNA during DNA replication. 5-Vinyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and induces DNA damage leads to apoptosis in human cultured cells .
    5-Vinyl-2'-deoxyuridine
  • HY-154253

    5-AmdU; α-Azidothymidine

    Nucleoside Antimetabolite/Analog Cancer
    5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells. . 5-Azidomethyl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5-Azidomethyl-2'-deoxyuridine
  • HY-W250162

    Deoxyuridine triphosphate

    DNA/RNA Synthesis Others
    dUTP (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position. Dutp can be used in PCR .
    dUTP
  • HY-118411
    5-Ethynyl-2'-deoxyuridine
    Maximum Cited Publications
    15 Publications Verification

    PROTAC Linkers Cancer
    5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    5-Ethynyl-2'-deoxyuridine
  • HY-112669
    5-Chloro-2'-deoxyuridine
    1 Publications Verification

    5-ChloroDeoxyuridine; CldU

    Nucleoside Antimetabolite/Analog Neurological Disease
    5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors.
    5-Chloro-2'-deoxyuridine
  • HY-13420
    Zebularine
    5 Publications Verification

    NSC309132; 4-Deoxyuridine

    DNA Methyltransferase Autophagy Cancer
    Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Zebularine also inhibits cytidine deaminase with a Ki of 0.95 μM.
    Zebularine
  • HY-W097792

    5'-O-DMT-dU

    DNA/RNA Synthesis Others
    5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
    5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
  • HY-48873

    DNA/RNA Synthesis Others
    5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
    5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite
  • HY-154143

    Nucleoside Antimetabolite/Analog Cancer
    3’-Beta-C-Ethynyl-4-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Beta-C-Ethynyl-4-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    3’-Beta-C-Ethynyl-4-deoxyuridine
  • HY-W011142

    Endogenous Metabolite Metabolic Disease
    2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
    2'-Deoxyuridine 5'-monophosphate disodium
  • HY-154329

    Nucleoside Antimetabolite/Analog Cancer
    2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Deoxyuridine
  • HY-154405

    Nucleoside Antimetabolite/Analog Cancer
    5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5’-Azido-5’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5’-Azido-5’-deoxyuridine
  • HY-152720

    Nucleoside Antimetabolite/Analog Others Cancer
    3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    3’-Azido-3’-deoxyuridine
  • HY-154211

    DNA/RNA Synthesis Others
    5’-O-DMTr-dU-methyl phosphonamidite; 5’-O-DMTr-2’-deoxyuridine-3’-O-(P-methyl-N,N-diisopropylamino)phosphonamidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    5'-O-DMTr-dU-methyl phosphonamidite
  • HY-152445

    Nucleoside Antimetabolite/Analog Others
    3’-Amino-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-Amino-3’-deoxyuridine
  • HY-W141338

    2'-Bromo-2'-deoxy-D-uridine

    Nucleoside Antimetabolite/Analog Cancer
    2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2′-Bromo-2′-deoxyuridine
  • HY-W154172

    Nucleoside Antimetabolite/Analog Cancer
    2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2′-Chloro-2′-deoxyuridine
  • HY-W251781

    2′-Deoxy-4-thiouridine; 4-ThioDeoxyuridine

    Nucleoside Antimetabolite/Analog Cancer
    4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4-Thio-2’-deoxyuridine
  • HY-154120

    Nucleoside Antimetabolite/Analog Cancer
    6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    6-Aza-2'-deoxyuridine
  • HY-152548

    Nucleoside Antimetabolite/Analog Others
    4’-C-Methyl-4-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4’-C-Methyl-4-deoxyuridine
  • HY-154237

    Nucleoside Antimetabolite/Analog Cancer
    5’-O-DMTr-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5’-O-DMTr-3’-deoxyuridine
  • HY-154533

    Nucleoside Antimetabolite/Analog Cancer
    3’-O-Acetyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-O-Acetyl-2’-deoxyuridine
  • HY-154239

    Nucleoside Antimetabolite/Analog Cancer
    5’-O-Triphenylmethyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5’-O-Triphenylmethyl-2’-deoxyuridine
  • HY-154026

    Nucleoside Antimetabolite/Analog Cancer
    5-Amino-2'-deoxyuridine (monohydrochloride) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Amino-2'-deoxyuridine monohydrochloride
  • HY-77645

    1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil

    Nucleoside Antimetabolite/Analog Cancer
    4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4',5'-Didehydro-5'-deoxyuridine
  • HY-152715

    Nucleoside Antimetabolite/Analog Others
    2’-C-β-Methyl-4-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-C-β-Methyl-4-deoxyuridine
  • HY-138253S

    dFdU-13C,15N2; 2',2'-Difluoro-2'-Deoxyuridine-13C,15N2

    Isotope-Labeled Compounds Others
    2′,2′-Difluorodeoxyuridine- 13C, 15N2 (dFdU- 13C, 15N2; 2',2'-Difluoro-2'-deoxyuridine- 13C, 15N2) is a 13C- and 15N-labeled compound.
    2′,2′-Difluorodeoxyuridine-13C,15N2
  • HY-W397503

    2'-Deoxy-5'-O-DMT-5-iodouridine

    Nucleoside Antimetabolite/Analog Cancer
    5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5’-O-DMTr-5-iodo-2’-deoxyuridine
  • HY-152618

    Nucleoside Antimetabolite/Analog Cancer
    3’-N-Acetyl-3’-amino-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-N-Acetyl-3’-amino-3’-deoxyuridine
  • HY-154238

    Nucleoside Antimetabolite/Analog Cancer
    5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
  • HY-154492

    Nucleoside Antimetabolite/Analog Cancer
    2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
    2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine

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