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2-(2-Furanyl)-5-methylpyrazine-d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (1) ADC Cytotoxin (2) AIM2 (1) Amyloid-β (1) Antibiotic (7) Apoptosis (12) Aryl Hydrocarbon Receptor (1) Autophagy (1) Bacterial (15) Beta-secretase (1) Biochemical Assay Reagents (2) Caspase (1) CD73 (1) CFTR (2) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) CRISPR/Cas9 (1) Cytochrome P450 (1) Dopamine Receptor (1) DYRK (1) E1/E2/E3 Enzyme (1) Endogenous Metabolite (2) ERK (1) Fungal (2) GABA Receptor (4) GSK-3 (1) Histone Methyltransferase (2) HIV (2) HMG-CoA Reductase (HMGCR) (1) IGF-1R (1) iGluR (2) Isotope-Labeled Compounds (27) JNK (1) Ketohexokinase (2) Microtubule/Tubulin (1) MMP (1) Neurokinin Receptor (1) NF-κB (2) NOD-like Receptor (NLR) (2) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (3) p38 MAPK (1) Parasite (5) PGE synthase (1) Phosphatase (1) Phosphodiesterase (PDE) (1) Phospholipase (1) PKA (1) Potassium Channel (1) Prostaglandin Receptor (1) Reactive Oxygen Species (3) RSV (2) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (1) Thymidylate Synthase (3) Topoisomerase (2) Wee1 (1)
By Research Areas:	Cancer (29) Cardiovascular Disease (1) Endocrinology (1) Infection (17) Inflammation/Immunology (13) Metabolic Disease (5) Neurological Disease (12)
Click Chemistry:	Azide (1)
Oligonucleotides:	Nucleosides and their Analogs (3) Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W067358

2-Methylpyrazine	Others	Others
2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils .

HY-156268S

*2-(2-Furanyl)-5-methylpyrazine-d3*	Isotope-Labeled Compounds	Others
2-(2-Furanyl)-5-methylpyrazine-d₃ is deuterated labeled 2-(2-Furanyl)-5-methylpyrazine.

HY-156269S

*2-(2-Furanyl)-6-methylpyrazine-d3*	Isotope-Labeled Compounds	Others
2-(2-Furanyl)-6-methylpyrazine-d₃ is deuterated labeled 2-(2-Furanyl)-6-methylpyrazine.

HY-W015855S

*2-Methoxy-3-methylpyrazine-d3* 2-Methoxy-3-methylpyrazine-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Methoxy-3-methylpyrazine-d₃ is deuterated labeled 2,3-Diethyl-5-methylpyrazine.

HY-W141038S

*2-Ethyl-5-methylpyrazine-d5* 2-Ethyl-5(6)-methylpyrazine-d<sub>5sub>	Isotope-Labeled Compounds	Others
2-Ethyl-5-methylpyrazine-d₅ is deuterated labeled 2,3-Diethylpyrazine.

HY-W067358R

*2-Methylpyrazine* (Standard)**	Others	Others
2-Methylpyrazine (Standard) is the analytical standard of 2-Methylpyrazine. This product is intended for research and analytical applications. 2-Methylpyrazine is a kind of?alkylpyrazine that can be identified in roasted red pepper seed oils .

HY-W067358S

*2-Methylpyrazine-d6*	Isotope-Labeled Compounds	Others
2-Methylpyrazine-d6 is the deuterium labeled 2-Methylpyrazine[1]. 2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils[2].

HY-155912S

*2-Allyl-3-methylpyrazine-d3*	Isotope-Labeled Compounds	Others
2-Allyl-3-methylpyrazine-d₃ is deuterated labeled 2-Allyl-3-methylpyrazine.

HY-W012832S

*2-Ethyl-3-methylpyrazine-d3* Pyrazine, 2-ethyl-3-methyl-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Ethyl-3-methylpyrazine-d₃ is deuterated labeled 3-Methylcyclopentane-1,2-dione.

HY-W101602S

*2-Isobutyl-3-methylpyrazine-d3* 2-Methyl-3-isobutylpyrazine-dsub>3sub>	Isotope-Labeled Compounds	Others
2-Isobutyl-3-methylpyrazine-d₃ is deuterated labeled 2-Ethylphenol.

HY-W015604S1

*2,3-Diethyl-5-methylpyrazine-d7* Pyrazine, 2,3-diethyl-5-methyl-d<sub>7sub>	Isotope-Labeled Compounds	Others
2,3-Diethyl-5-methylpyrazine-d₇ is deuterated labeled 2,4-Dimethylthiazole.

HY-32739

*5-Methylpyrazine-2-carboxylic acid*	Biochemical Assay Reagents	Others
5-Methylpyrazine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-65255

2-Amino-5-methylpyrazine	Biochemical Assay Reagents	Others
2-Amino-5-methylpyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W023443S

*2-Isopropyl-5-methylpyrazine-d3* 2-Methyl-5-(1-methylethyl)pyrazine-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Isopropyl-5-methylpyrazine-d₃ is deuterated labeled 5-Butyldihydrofuran-2(3H)-one.

HY-156347S

*(2-Methyl-3-furanyl)-dithio-2-propanone-d3*	Isotope-Labeled Compounds	Others
(2-Methyl-3-furanyl)-dithio-2-propanone-d₃ is deuterated labeled (2-Methyl-3-furanyl)-dithio-2-propanone.

HY-W423245S

*2,5-Diethyl-3-methylpyrazine-d3*	Isotope-Labeled Compounds	Others
2,5-Diethyl-3-methylpyrazine-d₃ is deuterated labeled Sec-butyl butyrate.

HY-152808

*6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine*	Nucleoside Antimetabolite/Analog	Others
6-(2-Furanyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W015604S

*2,3-Diethyl-5-methylpyrazine-13C2* Pyrazine, 2,3-diethyl-5-methyl-¹³C<sub>2sub>	Isotope-Labeled Compounds	Others
2,3-Diethyl-5-methylpyrazine- ¹³C₂ is ¹³C labeled 4-Hydroxy-5-methylfuran-3(2H)-one.

HY-152681

*N3-[(Tetrahydro-2-furanyl)methyl]uridine*	Nucleoside Antimetabolite/Analog	Others
N3-[(Tetrahydro-2-furanyl)methyl]uridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154613

*(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Cancer
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W160631S

2-Ethenylpyrazine-d3 2-Vinylpyrazine-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Ethenylpyrazine-d₃ is deuterated labeled 2-Ethyl-5-methylpyrazine.

HY-W014780S

2-Benzylideneheptanal-d5 α-Pentylcinnamaldehyde-d<sub>5sub>	Isotope-Labeled Compounds	Others
2-Benzylideneheptanal-d₅ is deuterated labeled 2-Ethyl-3-methylpyrazine.

HY-W099862S1

2-Ethylphenol-d2 1-Hydroxy-2-ethylbenzene-d<sub>2sub>	Isotope-Labeled Compounds	Others
2-Ethylphenol-d₂ is deuterated labeled 2-Isopropyl-5-methylpyrazine.

HY-W015778S

2-Methoxy-5-methylphenol-d3 Isocreosole-d<sub>3sub>	Isotope-Labeled Compounds	Others
2-Methoxy-5-methylphenol-d₃ is deuterated labeled 2,3-Diethyl-5-methylpyrazine.

HY-W017374S1

*4-Ethyl-2-methoxyphenol-d3* 4-Ethylguaiacol-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Ethyl-2-methoxyphenol-d₃ is deuterated labeled 2-Methoxy-3-methylpyrazine.

HY-W129470S

Pent-1-en-3-ol-d2 1-Penten-3-OL-d<sub>2sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
Pent-1-en-3-ol-d₂ is deuterated labeled 2-Isobutyl-3-methylpyrazine.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-W719396S

3,5-Dimethyl-2-vinylpyrazine-d3	Isotope-Labeled Compounds	Others
3,5-Dimethyl-2-vinylpyrazine-d₃ is deuterated labeled 2,5-Diethyl-3-methylpyrazine.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-157440

AChE/Aβ-IN-3	Amyloid-β Reactive Oxygen Species Cholinesterase (ChE)	Neurological Disease
AChE/Aβ-IN-3 (compound AM5) is a dual inhibitor of AChE and Amyloid-β aggregation with *IC_50<.sub>* values of 1.29 and 4.93 μM, respectively. AChE/Aβ-IN-3 has antioxidant properties that scavenge ROS and restore their normal levels. AChE/Aβ-IN-3 can be used in the study of neurological diseases, such as Alzheimer's disease .

HY-144290

ARN25068	GSK-3 DYRK	Neurological Disease
ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .

HY-N7118

Clindamycin hydrochloride monohydrate	Bacterial Antibiotic	Infection Cancer
Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .

HY-129946

Dopamine D2 receptor antagonist-1	Dopamine Receptor	Neurological Disease
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity .

HY-163129

BPU	Apoptosis MMP	Cancer
BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues .

HY-139823A

PRMT5-IN-11	Histone Methyltransferase	Others
PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.

HY-144220

NLRP3/AIM2-IN-1	NOD-like Receptor (NLR)	Inflammation/Immunology
NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an < b > IC < sub > 50 < / sub > < / b > value of 3.136 ± 0.7667 μ M.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Others	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-157728

ML307	E1/E2/E3 Enzyme	Inflammation/Immunology
ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC₅₀ of 781 nM. ML307 has the potential for immunomodulation and inflammation research .

HY-119095

L-741671	Neurokinin Receptor	Neurological Disease Endocrinology
L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.7 nM in rat, human and ferret, respectively .

HY-111258

GSK345931A	Prostaglandin Receptor	Neurological Disease Inflammation/Immunology
GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain .

HY-P3426

BACE1-IN-10	Beta-secretase	Cancer
BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .

HY-B1455

Clindamycin 5+ Cited Publications	Bacterial Antibiotic Parasite	Infection Cancer
Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .

HY-111673

8-CPT-Cyclic AMP sodium 8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC₅₀ of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC_{50 s of 24 and 25 μM, respectively. 8-CPT-Cyclic AMP sodium is a very high affinity for Epac and is a potent Epac activator .}

HY-U00037

Ecopladib PLA 725	Phospholipase	Inflammation/Immunology
Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC₅₀s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.

HY-111192

IPR-803 2 Publications Verification	Ser/Thr Protease	Cancer
IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .

HY-144238

mPGES1-IN-6	PGE synthase	Inflammation/Immunology
MPGES-1 is considered as a promising therapeutic target of the next generation anti-inflammatory drugs in the research of inflammatory diseases. The < b > IC < sub > 50 < / sub > < / b > value of mPGES1-IN-6 is 0.03 μ M。

HY-W102714

1,2-Cyclohexylenedinitrilotetraacetic acid CDTA	Others	Metabolic Disease
1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .

HY-144232

Anticancer agent 28	Others	Cancer
Anticancer agent 28 showed good antitumor activity in H22 allogeneic mice in vivo. Its potency in K562 cells was 50 times that of oridonin, and its < b > IC < sub > 50 < / sub > < / b > value was 0.09 μ M。

Cat. No.	Product Name	Type

HY-65255

2-Amino-5-methylpyrazine	Biochemical Assay Reagents
2-Amino-5-methylpyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-32739

*5-Methylpyrazine-2-carboxylic acid*	Biochemical Assay Reagents
5-Methylpyrazine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W034392

Stewart-Grubbs catalyst

Biochemical Assay Reagents

Stewart-Grubbs catalyst is an effective catalyst for the cross-metathesis of olefins with a large number of allylic substituents. In addition, ChemBeads are chemically coated glass beads that improve flowability and chemical homogeneity, making them ideal for automated solid dispensing and high-throughput experiments. Notably, the manufacture of ChemBeads does not require additional chemicals or surfactants, allowing for precise dispensing of sub-milligram amounts of catalyst.

Cat. No.	Product Name	Target	Research Area

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Peptides	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P3426

BACE1-IN-10	Beta-secretase	Cancer
BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P2592

Ro 23-7014	Peptides	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

Cat. No.	Product Name	Target	Research Area

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W067358

2-Methylpyrazine	Natural Products Capsicum annuum L. Classification of Application Fields Source classification Other Diseases Plants Solanaceae Disease Research Fields	Others
2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	Classification of Application Fields Disease Research Fields Cancer	IGF-1R
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-W067358R

*2-Methylpyrazine* (Standard)**	Structural Classification Natural Products Capsicum annuum L. Classification of Application Fields Source classification Other Diseases Solanaceae Plants Disease Research Fields	Others
2-Methylpyrazine (Standard) is the analytical standard of 2-Methylpyrazine. This product is intended for research and analytical applications. 2-Methylpyrazine is a kind of?alkylpyrazine that can be identified in roasted red pepper seed oils .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

Species:	Human (13)
Tag:	GFP (3) His (12) Strep (5) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P703334

	ABCF3 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human	Human	HEK293
	ABCF3 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCF3, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCF3 Protein, Human (HEK293, His, Strep, Flag) is 708 a.a.,

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P703309

	ABCA6 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family A member 6; ABCA6; Homo sapiens; Human; Translocase	Human	HEK293
	ABCA6 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCA6, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCA6 Protein, Human (HEK293, His, Strep, Flag) is 1616 a.a.,

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Human (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q, , , , mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P703304

	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703305

	ABCB10 Protein, Human (HEK293, Flag, His, N229A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703306

	ABCB10 Protein, Human (HEK293, Flag, His, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703307

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703308

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-156268S

*2-(2-Furanyl)-5-methylpyrazine-d3*
2-(2-Furanyl)-5-methylpyrazine-d₃ is deuterated labeled 2-(2-Furanyl)-5-methylpyrazine.

HY-156269S

*2-(2-Furanyl)-6-methylpyrazine-d3*
2-(2-Furanyl)-6-methylpyrazine-d₃ is deuterated labeled 2-(2-Furanyl)-6-methylpyrazine.

HY-W015855S

*2-Methoxy-3-methylpyrazine-d3*
2-Methoxy-3-methylpyrazine-d₃ is deuterated labeled 2,3-Diethyl-5-methylpyrazine.

HY-W141038S

*2-Ethyl-5-methylpyrazine-d5*
2-Ethyl-5-methylpyrazine-d₅ is deuterated labeled 2,3-Diethylpyrazine.

HY-W067358S

*2-Methylpyrazine-d6*
2-Methylpyrazine-d6 is the deuterium labeled 2-Methylpyrazine[1]. 2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils[2].

HY-155912S

*2-Allyl-3-methylpyrazine-d3*
2-Allyl-3-methylpyrazine-d₃ is deuterated labeled 2-Allyl-3-methylpyrazine.

HY-W012832S

*2-Ethyl-3-methylpyrazine-d3*
2-Ethyl-3-methylpyrazine-d₃ is deuterated labeled 3-Methylcyclopentane-1,2-dione.

HY-W101602S

*2-Isobutyl-3-methylpyrazine-d3*
2-Isobutyl-3-methylpyrazine-d₃ is deuterated labeled 2-Ethylphenol.

HY-W015604S1

*2,3-Diethyl-5-methylpyrazine-d7*
2,3-Diethyl-5-methylpyrazine-d₇ is deuterated labeled 2,4-Dimethylthiazole.

HY-W023443S

*2-Isopropyl-5-methylpyrazine-d3*
2-Isopropyl-5-methylpyrazine-d₃ is deuterated labeled 5-Butyldihydrofuran-2(3H)-one.

HY-156347S

*(2-Methyl-3-furanyl)-dithio-2-propanone-d3*
(2-Methyl-3-furanyl)-dithio-2-propanone-d₃ is deuterated labeled (2-Methyl-3-furanyl)-dithio-2-propanone.

HY-W423245S

*2,5-Diethyl-3-methylpyrazine-d3*
2,5-Diethyl-3-methylpyrazine-d₃ is deuterated labeled Sec-butyl butyrate.

HY-W015604S

*2,3-Diethyl-5-methylpyrazine-13C2*
2,3-Diethyl-5-methylpyrazine- ¹³C₂ is ¹³C labeled 4-Hydroxy-5-methylfuran-3(2H)-one.

HY-W160631S

2-Ethenylpyrazine-d3
2-Ethenylpyrazine-d₃ is deuterated labeled 2-Ethyl-5-methylpyrazine.

HY-W014780S

2-Benzylideneheptanal-d5
2-Benzylideneheptanal-d₅ is deuterated labeled 2-Ethyl-3-methylpyrazine.

HY-W099862S1

2-Ethylphenol-d2
2-Ethylphenol-d₂ is deuterated labeled 2-Isopropyl-5-methylpyrazine.

HY-W015778S

2-Methoxy-5-methylphenol-d3
2-Methoxy-5-methylphenol-d₃ is deuterated labeled 2,3-Diethyl-5-methylpyrazine.

HY-W017374S1

*4-Ethyl-2-methoxyphenol-d3*
4-Ethyl-2-methoxyphenol-d₃ is deuterated labeled 2-Methoxy-3-methylpyrazine.

HY-W129470S

Pent-1-en-3-ol-d2
Pent-1-en-3-ol-d₂ is deuterated labeled 2-Isobutyl-3-methylpyrazine.

HY-W719396S

3,5-Dimethyl-2-vinylpyrazine-d3
3,5-Dimethyl-2-vinylpyrazine-d₃ is deuterated labeled 2,5-Diethyl-3-methylpyrazine.

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B1455S

Clindamycin-d3 hydrochloride

Clindamycin-d₃ (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2].

HY-B1455S1

Clindamycin-13C,d3

Clindamycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2][3].

HY-17504BS2

Rosuvastatin-13C,d3 sodium

Rosuvastatin- ¹³C,d₃ sodium is ¹³C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM . Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-B1689AS

Methantheline-d3 bromide
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide[1].

HY-W014839S1

Cyclamic acid-d4 sodium
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

HY-17413S

Zidovudine-d3

Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B0184S1

Felbamate-d5
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-B1773AS5

Sodium Propionate-d3
Sodium Propionate-d₃ is the deuterium labeled Sodium Propionate[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80527

	ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
	ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80772

	P Glycoprotein Antibody p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

	MRP2 Antibody ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; Canalicular multidrug resistance protein antibody; Canalicular multispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_HUMAN antibody; Multidrug resistance associated protein 2 antibody; Multidrug resistance-associated protein 2 antibody;	WB, ICC/IF, FC	Human
	MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.

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Clonality
Immunogen
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Formulation
Free Sample	Yes No
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Cat. No.	Product Name		Classification

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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2-(2-Furanyl)-5-methylpyrazine-d<sub>3</sub>

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