Search Result

Results for "

Aminoglycoside antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (60) ATP Synthase (1) Bacterial (52) Drug Metabolite (1) Fungal (5) Isotope-Labeled Compounds (1) Parasite (6) PDI (1) Phospholipase (2) Tyrosinase (2)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Infection (59) Inflammation/Immunology (2) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1915

Micronomicin Gentamicin C2b; antibiotic XK-62-2; Sagamicin	Antibiotic Bacterial	Infection
Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities .

HY-B1329

Apramycin sulfate 3 Publications Verification Nebramycin II sulfate	Bacterial Antibiotic	Infection
Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside *antibiotic* which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-N7449

Neamine	Antibiotic Bacterial	Infection Cardiovascular Disease Neurological Disease Cancer
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-115349

Neamine tetrahydrochloride	Antibiotic Bacterial	Infection Neurological Disease Cancer
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .

HY-N125722

Venturicidin A Aabomycin A1	ATP Synthase Antibiotic	Infection
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.

HY-B0472

Streptomycin sulfate 25+ Cited Publications	Bacterial Antibiotic	Infection
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B1743

Puromycin Maximum Cited Publications 219 Publications Verification CL13900	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-150520

Neomycin	Antibiotic	Infection Cancer
Neomycin is an aminoglycoside antibiotic. Neomycin can be used for the research of external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt .

HY-B1329R

Apramycin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-122350

Dactimicin sulfate SF-2052 sulfate	Antibiotic	Infection
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .

HY-17558

Apramycin Nebramycin II	Bacterial Antibiotic	Infection
Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine.

HY-B0490

Hygromycin B 20+ Cited Publications Hygrovetine	Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-B1241

Dihydrostreptomycin sulfate DHSM sulfate	Bacterial Antibiotic	Infection
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep.

HY-B1864C

Kasugamycin sulfate Ksg sulfate	Antibiotic Fungal	Infection
Kasugamycin (sulfate) is an **aminoglycoside antibiotic that can be used to treat rice blast caused by fungi** .

HY-121474

Dactimicin SF-2052	Antibiotic Bacterial	Infection
Dactimicin is a pseudodisaccharide aminoglycoside. Dactimicin is an antibiotic that can inhibit the growth of methicillin-susceptible S. aureus isolates and coagulase-negative staphylococci with MIC₅₀s of 2 μg/mL. Dactimicin is active against organisms possessing aminoglycoside-modifying enzymes .

HY-B1743S

Puromycin-d3 3 Publications Verification CL13900-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B0755

Etimicin sulfate	Antibiotic	Infection
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.

HY-127054

Netilmicin Sch 20569	Antibiotic Bacterial	Infection
Netilmicin (Sch 20569) is an antibiotic. Netilmicin exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL .

HY-B2094

Arbekacin	Antibiotic Bacterial	Infection
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria .

HY-B1222A

Sisomicin 5 Publications Verification antibiotic 6640; Rickamicin	Bacterial Antibiotic	Infection
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-B1174

Bekanamycin Kanamycin B	Antibiotic Bacterial	Infection
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-108718

G-418 Geneticin; antibiotic G-418	Bacterial Parasite Antibiotic	Infection
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .

HY-B0472R

Streptomycin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-W129471R

2-Pentadecanone (Standard)	Bacterial	Others
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B1222

Sisomicin sulfate 5 Publications Verification	Bacterial Antibiotic	Infection
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria .

HY-B0490R

Hygromycin B (Standard)	Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-A0086

Netilmicin sulfate SCH-20569 sulfate	Bacterial Antibiotic	Infection
Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.

HY-B0441A

Tobramycin sulfate 5+ Cited Publications Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate	Bacterial Antibiotic	Infection Cancer
Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .

HY-142127

Ribostamycin Vistamycin; SF-733	Bacterial Antibiotic PDI	Infection
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside *antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI* .

HY-133929

Gentamicin B SCH-14342	Bacterial Antibiotic	Infection
Gentamicin B (SCH-14342) is an aminoglycoside antibiotic that can be isolated from Micromonospora echinospora. Gentamicin B can be used for the research of ataxia potential and renal toxicity .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; antibiotic XK-62-2 sulfate; Sagamicin sulfate	Antibiotic Bacterial	Infection
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside *antibiotic* isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-17561

G-418 disulfate 35+ Cited Publications Geneticin sulfate; antibiotic G-418 sulfate	Bacterial Antibiotic	Infection
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .

HY-100589

Isepamicin sulfate Sch 21420 sulfate	Bacterial Antibiotic	Infection
Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .

HY-123162A

Astromicin disulfate Fortimicin A disulfate; KW-1070 disulfate	Antibiotic Bacterial	Infection
Astromicin disulfate is a water-soluble aminoglycoside *antibiotic* that can be isolated from the genus Micromonospora. Astromicin disulfate exhibits broad spectrum antibacterial activity against gram positive and negative bacteria .

HY-B1222AR

Sisomicin (Standard)	Bacterial Antibiotic	Infection
Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-B1174R

Bekanamycin (Standard)	Antibiotic Bacterial	Infection
Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-A0276A

Gentamicin 30+ Cited Publications	Antibiotic Bacterial	Infection Cancer
Gentamicin, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC₅₀ of 0.57 mM .

HY-B0441

Tobramycin 5+ Cited Publications Nebramycin Factor 6; Deoxykanamycin B	Bacterial Antibiotic	Infection Cancer
Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-A0276

Gentamicin sulfate 30+ Cited Publications	Bacterial Antibiotic	Infection Cancer
Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC₅₀ of 0.57 mM .

HY-B1222R

Sisomicin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [4].

HY-A0086R

Netilmicin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Netilmicin (sulfate) (Standard) is the analytical standard of Netilmicin (sulfate). This product is intended for research and analytical applications. Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.

HY-B0470

Neomycin sulfate 40+ Cited Publications	Bacterial Antibiotic Phospholipase	Infection Cancer
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-130066

Fortimicin C	Antibiotic Bacterial	Infection
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .

HY-B0441R

Tobramycin (Standard)	Bacterial Antibiotic	Infection Cancer
Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-125643R

Pitavastatin lactone (Standard)	Drug Metabolite	Cardiovascular Disease
Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-B0956

Paromomycin sulfate 2 Publications Verification Aminosidine sulfate	Antibiotic Parasite Bacterial	Infection
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside *antibiotic* with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-106668

Isepamicin Sch 21420	Antibiotic Bacterial	Infection
Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance .

HY-A0276R

Gentamicin (sulfate) (Standard)	Bacterial Antibiotic	Infection Cancer
Gentamicin (sulfate) (Standard) is the analytical standard of Gentamicin (sulfate). This product is intended for research and analytical applications. Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM .

HY-B0509

Amikacin hydrate 10+ Cited Publications BAY 41-6551 hydrate	Bacterial Antibiotic	Infection Cancer
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-167841

Anti-MRSA agent 19	Bacterial Antibiotic	Infection
Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against S. aureus. Anti-MRSA agent 19 is a active (median MIC=4 μg/mL) against 40 CDC isolates of different bacterial species containing various resistance factors, including Vancomycin (HY-B0671), aminoglycoside/Tetracycline (HY-A0107), and oxazolidinone resistance .

Cat. No.	Product Name

HY-L042

Glycoside Compound Library

793 compounds

Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities.

MCE Glycoside Compound Library contains a unique collection of 793 glycoside compounds and is a useful tool to discovery glycoside drugs.

Cat. No.	Product Name

HY-K1056

G418 Selective Antibiotic, Sterile 3 Publications Verification
MCE G418 Selective Antibiotic, Sterile is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

HY-K1055

Kanamycin sulfate (100x), Sterile
Kanamycin sulfate is an aminoglycoside antibiotic purified from Streptomyces kanamyceticus. It acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis in susceptible bacteria.

Cat. No.	Product Name	Category	Target	Chemical Structure