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Anti-spasmodic,

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) AMPK (1) Antibiotic (1) Bacterial (3) Calcium Channel (10) Calmodulin (1) Cholinesterase (ChE) (1) COMT (1) Cytochrome P450 (1) Drug Metabolite (4) EGFR (2) Endogenous Metabolite (1) FKBP (1) Fungal (2) HBV (3) Histamine Receptor (3) iGluR (1) Influenza Virus (1) Isotope-Labeled Compounds (5) Keap1-Nrf2 (1) mAChR (19) Monoamine Oxidase (1) Neurokinin Receptor (1) NF-κB (2) Parasite (1) Phosphatase (1) Phosphodiesterase (PDE) (5) Potassium Channel (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (5) Endocrinology (1) Infection (8) Inflammation/Immunology (19) Metabolic Disease (10) Neurological Disease (57)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

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Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2604

Loureirin C	Bacterial	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Loureirin C has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti-tumor activities .

HY-B0326

Alibendol	Others	Endocrinology
Alibendol can be taken orally. It has anti-spasmodic properties and promotes bile secretion, making it useful for research on digestive system issues like indigestion, nausea, vomiting, and constipation .

HY-N0820

Catalpol Maximum Cited Publications 8 Publications Verification Catalpinoside	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N5086

Picroside IV	HBV	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-13557

Ascomycin 5+ Cited Publications Immunomycin; FR-900520; FK520	FKBP Parasite Fungal Antibiotic	Infection Neurological Disease Inflammation/Immunology
Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .

HY-133153S

Fenpiverinium-d3 bromide	Isotope-Labeled Compounds	Neurological Disease
Fenpiverinium-d₃ (bromide) is a deuterium labeled Fenpiverinium bromide. Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects[1].

HY-N0820R

Catalpol (Standard)	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-U00195

Piperylone PR66	Others	Neurological Disease
Piperylone can be used as an antispasmodic.

HY-105738

Butaverine	Others	Neurological Disease
Butaverine is an antispasmodic compound .

HY-160994

Pyrophendane	Others	Others
Pyrophendane is an antispasmodic agent .

HY-W201842

Octamylamine	mAChR	Neurological Disease
Octamylamine is an anticholinergic and antispasmodic agent .

HY-W201842B

Octamylamine hydrochloride	mAChR	Neurological Disease
Octamylamine hydrochloride is an anticholinergic and antispasmodic agent .

HY-W201842A

Octamylamine sulfamate	mAChR	Neurological Disease
Octamylamine sulfamate is an anticholinergic and antispasmodic agent .

HY-B0549AS

Flavoxate-d4 hydrochloride	mAChR	Neurological Disease
Flavoxate-d₄ (hydrochloride) (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate Hydrochloride is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic[1][2].

HY-N4113

Glycycoumarin	Keap1-Nrf2 AMPK	Cancer
Glycycoumarin is a potent *antispasmodic* agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-12770

Mebeverine alcohol Mebeverine metabolite Mebeverine alcohol	Drug Metabolite	Neurological Disease
Mebeverine alcohol is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug.

HY-122086

Prifinium bromide	mAChR	Neurological Disease
Prifinium bromide is antimuscarinic agent with antispasmodic, antiemetic effect .

HY-12771

O-desmethyl Mebeverine acid Mebeverine metabolite O-desmethyl Mebeverine acid	Drug Metabolite	Neurological Disease
O-desmethyl Mebeverine acid is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug.

HY-105652

Ambucetamide	Others	Neurological Disease
Ambucetamide is an antispasmodic agent. Ambucetamide alleviates menstrual pain .

HY-I0637

Isovanillin 3-Hydroxy-4-methoxybenzaldehyde	Others	Neurological Disease Metabolic Disease
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-12769S

Mebeverine acid-d5	Drug Metabolite	Neurological Disease
Mebeverine acid-d₅ is the deuterium labeled Mebeverine Acid; Mebeverine Acid is a metabolite of Mebeverine, that is an antispasmodic.

HY-116755

Tiropramide CR 605	Others	Others
Tiropramide is an antispasmodic agent that plays important roles in spasmodic pain of the hepatobiliary and urinary tract .

HY-107349

Fenoverine Spasmopriv	Calcium Channel	Neurological Disease
Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents . Fenoverine induces rhabdomyolysis .

HY-105771

Parapenzolate bromide	mAChR	Neurological Disease
Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

HY-N2842

α-Amyrin acetate	Others	Inflammation/Immunology
α-Amyrin acetate, a natural triterpenoid, has anti-inflammatory activity, antispasmodic profile and the relaxant effect .

HY-120695

Nafiverine	Others	Neurological Disease
Nafiverine is an antispasmodic agent. Nafiverine shows a high myolytic activity on the smooth muscles of the ileum, uterus, and coronary vessels .

HY-118524

Dipiproverine LD-935 free base	Others	Neurological Disease
Dipiproverine (LD-935 free base) is an alpha-amino acid ester, an antispasmodic compound, which is used as an anticholinergic agent .

HY-12769

Mebeverine acid Mebeverine metabolite Mebeverine acid	Drug Metabolite	Neurological Disease
Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine. Mebeverine is an antispasmodic agent. Mebeverine acid is a valuable marker of oral exposure to Mebeverine .

HY-122520

Fentonium bromide	Others	Neurological Disease
Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions .

HY-118524A

Dipiproverine hydrochloride LD-935	Others	Neurological Disease
Dipiproverine (hydrochloride) is the hydrochloride form of Dipiproverine (HY-118524). Dipiproverine (hydrochloride) is an alpha-amino acid ester, an antispasmodic compound, which is used as an anticholinergic agent .

HY-105853

Pitofenone	Others	Neurological Disease
Pitofenone is an orally active antispasmodic agent with anticholinergic and musculotropic activities in various smooth muscles. Pitofenone can be utilized in spasm research .

HY-100562

Flopropione	5-HT Receptor COMT	Neurological Disease
Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor . Flopropione also as an antispasmodic agent .

HY-111025

Ectylurea	Others	Neurological Disease
Ectylurea，a N-acylurea，can be used in studies of tension and anxiety symptoms, has no effect on the autonomic nervous system, and has no convulsive, analgesic or antispasmodic activity in animals .

HY-I0637R

Isovanillin (Standard)	Others	Neurological Disease Metabolic Disease
Isovanillin (Standard) is the analytical standard of Isovanillin. This product is intended for research and analytical applications. Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-167739

(S,S)-Dehydroemetine	Others	Neurological Disease
(S,S)-Dehydroemetine is an antispasmodic compound with inhibitory activity on smooth muscle. (S,S)-Dehydroemetine can be used to inhibit diseases related to smooth muscle contraction .

HY-I0637S

Isovanillin-d3 3-Hydroxy-4-methoxybenzaldehyde-d₃	Isotope-Labeled Compounds	Metabolic Disease
Isovanillin-d₃ is the deuterium labeled Isovanillin[1]. Isovanillin is an aldehyde oxidase inhibitor[2]. Antispasmodic activities[3]. Antidiarrheal activities[4].

HY-121020

Arcapillin	Phosphatase	Neurological Disease
Arcapillin is a flavonoid that can be isolated from Artemisia capillaris Thunb. Arcapillin has antispasmodic activity. Arcapillin also has moderate PTP1B inhibitory activity .

HY-107349R

Fenoverine (Standard)	Calcium Channel	Neurological Disease
Fenoverine (Standard) is the analytical standard of Fenoverine. This product is intended for research and analytical applications. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents . Fenoverine induces rhabdomyolysis .

HY-126568

Naftidrofuryl Nafronyl	Others	Cardiovascular Disease
Naftidrofuryl (Nafronyl) is a compound that has the ability to enhance cellular oxidative capacity and antispasmodic activity. Naftidrofuryl is used to inhibit peripheral and cerebrovascular diseases. Naftidrofuryl is claimed to improve blood circulation .

HY-107349S

Fenoverine-d8 Spasmopriv-d₈	Calcium Channel	Neurological Disease
Fenoverine-d₈ is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

HY-B1440

Ethaverine hydrochloride	Calcium Channel Monoamine Oxidase	Cardiovascular Disease
Ethaverine hydrochloride, a derivative of papaverine, inhibits cardiac L-type calcium channel. Ethaverine hydrochloride is a peripheral vasodilator and antispasmodic agent. Ethaverine hydrochloride can be used for research of peripheral vascular disease .

HY-122409

Cularine	Others	Others
Cularine is a compound that relaxes guinea pig tracheal and human bronchial smooth muscle, inhibits contraction induced by a variety of contractile agents, and has nonspecific antispasmodic activity, and its activity is structure-related.

HY-106745

Elziverine Ro 22-4839	Calmodulin	Cardiovascular Disease
Elziverine (Ro 22-4839) is a brain circulation improvement agent with vasospasm antispasmodic effects. Elziverine is a calmodulin antagonist. Elziverine inhibits erythrocyte cell membrane rupture, platelet aggregation and lipid peroxidation .

HY-N2746

7-O-Geranylscopoletin 7-Geranyloxy-6-methoxycoumarin	Others	Neurological Disease Metabolic Disease
7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia .

HY-N2050

1,3,5,8-Tetrahydroxyxanthone 1 Publications Verification Desmethylbellidifolin	Others	Neurological Disease Inflammation/Immunology
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Endogenous Metabolite	Neurological Disease Metabolic Disease
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-136634

BTM-1042	Others	Others
BTM-1042 is a newly synthesized compound with antispasmodic effects. It can inhibit the twitch reaction of the guinea pig ileum under electrical stimulation and is not affected by naloxone. It has similar effects to atropine and can block muscarinic receptors, but has less effect on other types of receptors. BTM-1042 also has an inhibitory effect on the ileal reaction caused by nicotine and 5-hydroxytryptamine. BTM-1042 showed a dose-dependent inhibitory effect on the spontaneous movement of the rabbit stomach. In general, BTM-1042 is a agent with a strong antispasmodic effect.

HY-B1394

Khellin 1 Publications Verification	EGFR	Cardiovascular Disease Cancer
Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC₅₀ of 0.15 µM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects .

HY-119918

Cycrimine	mAChR	Neurological Disease
Cycrimine is an orally active muscarinic cholinergic receptor (mAChR) M1 antagonist, reduces the acetylcholine levels in parkinson model. Cycrimine shows antispasmodic activity, can be used in studies of behavioral and mental disorder .

HY-108964

Carvone	Bacterial	Infection Neurological Disease Inflammation/Immunology
Carvone is a ketone monoterpene found mostly in the essential oils from plants of the genus Mentha. Carvone is widely used in the pharmaceutical industry, cosmetics and agriculture. Carvone has such effects as antimicrobial, antioxidant, anti-inflammatory, antispasmodic, antinociceptive, anticonvulsant .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2604

Loureirin C	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Metabolic Disease Plants Infection other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Bacterial
Loureirin C has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti-tumor activities .

HY-N0820

Catalpol Maximum Cited Publications 8 Publications Verification Catalpinoside	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Infection Iridoids Terpenoids Scrophulariaceae Inflammation/Immunology Disease Research Fields Cancer	HBV
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N5086

Picroside IV	Structural Classification Neurological Disease Classification of Application Fields Source classification Metabolic Disease Plants Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	HBV
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-13557

Ascomycin 5+ Cited Publications Immunomycin; FR-900520; FK520	Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antifungal Macrolide Antibiotics Neurological Disease Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields	FKBP Parasite Fungal Antibiotic
Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .

HY-N4113

Glycycoumarin	Structural Classification Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Cancer	Keap1-Nrf2 AMPK
Glycycoumarin is a potent *antispasmodic* agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-I0637

Isovanillin 3-Hydroxy-4-methoxybenzaldehyde	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Asclepiadaceae Phenols Plants Periploca sepium Bunge	Others
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-N2842

α-Amyrin acetate	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology	Others
α-Amyrin acetate, a natural triterpenoid, has anti-inflammatory activity, antispasmodic profile and the relaxant effect .

HY-100562

Flopropione	Entada phaseoloides (L.) Merr. Neurological Disease Classification of Application Fields Labiatae Source classification Phenols Polyphenols Plants Disease Research Fields	5-HT Receptor COMT
Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor . Flopropione also as an antispasmodic agent .

HY-N0820R

Catalpol (Standard)	Structural Classification Iridoids Terpenoids Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey	HBV
Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-I0637R

Isovanillin (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Asclepiadaceae Phenols Plants Periploca sepium Bunge	Others
Isovanillin (Standard) is the analytical standard of Isovanillin. This product is intended for research and analytical applications. Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-121020

Arcapillin	Structural Classification Flavonoids Flavones Source classification Plants Compositae Artemisia capillaris Thunb.	Phosphatase
Arcapillin is a flavonoid that can be isolated from Artemisia capillaris Thunb. Arcapillin has antispasmodic activity. Arcapillin also has moderate PTP1B inhibitory activity .

HY-N2746

7-O-Geranylscopoletin 7-Geranyloxy-6-methoxycoumarin	Source classification Rutaceae Atalantia buxifolia (Poir.) Oliv. Coumarins Phenylpropanoids Plants	Others
7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia .

HY-N2050

1,3,5,8-Tetrahydroxyxanthone 1 Publications Verification Desmethylbellidifolin	Structural Classification Xanthones Neurological Disease Classification of Application Fields Source classification Plants other families Gentianaceae Phenols Polyphenols Swertia chirata Inflammation/Immunology Disease Research Fields	Others
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-B1394

Khellin 1 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Artemisia cana Pursh Source classification Lignans Phenylpropanoids Umbelliferae Plants Disease Research Fields	EGFR
Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC₅₀ of 0.15 µM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects .

HY-108964

Carvone	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Umbelliferae Isodon japonicus (Burm. f.) H. Hara	Bacterial
Carvone is a ketone monoterpene found mostly in the essential oils from plants of the genus Mentha. Carvone is widely used in the pharmaceutical industry, cosmetics and agriculture. Carvone has such effects as antimicrobial, antioxidant, anti-inflammatory, antispasmodic, antinociceptive, anticonvulsant .

HY-W230975

(E/Z)-Piperine (E/Z)-Bioperine; (E/Z)-1-Piperoylpiperidine	Structural Classification Alkaloids Piperidine Alkaloids Source classification Piperaceae Plants Piper nigrum Linn.	Others
(E/Z)-Piperine ((E/Z)-Bioperine) is an alkaloid with a pungent property. (E/Z)-Piperine shows anti-inflammation, immunomodulatory and anti-cancer, antispasmodic and anti-secretory effects. (E/Z)-Piperine demonstrates significant neuroprotective effect in Alzheimer’s disease and Parkinson’s disease .

HY-B1394R

Khellin (Standard)	Structural Classification Artemisia cana Pursh Source classification Lignans Phenylpropanoids Umbelliferae Plants	EGFR
Khellin (Standard) is the analytical standard of Khellin. This product is intended for research and analytical applications. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects .

HY-108964R

Carvone (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Umbelliferae Plants Isodon japonicus (Burm. f.) H. Hara	Bacterial
Carvone (Standard) is the analytical standard of Carvone. This product is intended for research and analytical applications. Carvone is a ketone monoterpene found mostly in the essential oils from plants of the genus Mentha. Carvone is widely used in the pharmaceutical industry, cosmetics and agriculture. Carvone has such effects as antimicrobial, antioxidant, anti-inflammatory, antispasmodic, antinociceptive, anticonvulsant .

HY-14621

Zingerone 4 Publications Verification Vanillylacetone; Gingerone	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Zingiber officinale Roscoe Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Inflammation/Immunology Disease Research Fields Zingiberaceae	NF-κB
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-N11706

β-Cedrene (+)-β-Cedrene	Centaurea kotschyi (Boiss.) Hayek Structural Classification Natural Products Source classification Plants Compositae	Fungal
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-14621R

Zingerone (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Plants Zingiberaceae	NF-κB
Zingerone (Standard) is the analytical standard of Zingerone. This product is intended for research and analytical applications. Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

Cat. No.	Product Name	Chemical Structure

HY-107349S

Fenoverine-d8
Fenoverine-d₈ is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

HY-133153S

Fenpiverinium-d3 bromide
Fenpiverinium-d₃ (bromide) is a deuterium labeled Fenpiverinium bromide. Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects[1].

HY-B0549AS

Flavoxate-d4 hydrochloride
Flavoxate-d₄ (hydrochloride) (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate Hydrochloride is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic[1][2].

HY-12769S

Mebeverine acid-d5
Mebeverine acid-d₅ is the deuterium labeled Mebeverine Acid; Mebeverine Acid is a metabolite of Mebeverine, that is an antispasmodic.

HY-I0637S

Isovanillin-d3
Isovanillin-d₃ is the deuterium labeled Isovanillin[1]. Isovanillin is an aldehyde oxidase inhibitor[2]. Antispasmodic activities[3]. Antidiarrheal activities[4].

HY-108974S

Drotaverine-d10 hydrochloride

Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

HY-12752BS

Alimemazine-d6 hydrochloride

Alimemazine-d6 hydrochloride (Trimeprazine-d6 hydrochloride) is the deuterium labeled Alimemazine (HY-12752). Alimemazine is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.Alimemazine (Trimeprazine) is also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs. Alimemazine displays antiserotonin, antispasmodic, and antiemetic properties .

HY-B1339AS

Dicyclomine-d4

Dicyclomine-d₄ is the deuterium labeled Dicyclomine[1]. Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[2]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[3].

HY-B0267BS

Oxybutynin-d5 hydrochloride

Oxybutynin-d₅ hydrochloride is deuterated labeled (R)-Oxybutynin hydrochloride (HY-B0267B). (R)-Oxybutynin hydrochloride, a (R)-isomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used for researching incontinence due to neurogenic bladder dysfunction . (R)-Oxybutynin hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine		Phospholipids
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

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Anti-spasmodic,

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NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

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