2. Search Result
Search Result
Results for "

Carboxamides

" in MedChemExpress (MCE) Product Catalog:

62

Inhibitors & Agonists

2

Biochemical Assay Reagents

11

Peptides

4

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-138698
    FT206

    		Deubiquitinase Others
    FT206 is an inhibitor of carboxamides as ubiquitin-specific protrase extracted from patent WO 2020033707 A1, example 11-1 .
    FT206
  • HY-103592
    ARN14974

    		Ceramidase Cancer
    ARN14974, a benzoxazolone carboxamide, is a potent and systemically active inhibitors of intracellular acid ceramidase (IC50=79 nM) .
    ARN14974
  • HY-17520
    Penthiopyrad

    MTF-753

    		 Fungal Infection
    Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
    Penthiopyrad
  • HY-147416
    Vipoglanstat

    BI 1029539; GS-248; OX-MPI

    		 PGE synthase Infection Cancer
    Vipoglanstat (BI 1029539), a carboxamide, is a potent and selective, non-peptide and orally active small molecular inhibitor of human prostaglandin E synthase 1 (mPGES-1). Vipoglanstat also has anti-inflammatory activity .
    Vipoglanstat
  • HY-W012921
    (R)-Pyrrolidine-2-carboxamide

    		Amino Acid Derivatives Others
    (R)-Pyrrolidine-2-carboxamide is a proline derivative .
    (R)-Pyrrolidine-2-carboxamide
  • HY-163407
    Galectin-3-IN-4

    		Galectin Cancer
    Galectin-3-IN-4 (compound 5) is a carboxamide analog. Galectin-3-IN-4 is a potent, selective, and orally bioavailable inhibitor of human and mouse galectin-3, with IC50 values of 21 and 167 nM for hGal-3 and mGal-3, respectively. Galectin-3-IN-4 has IC50 values of 1580 and 2750 nM for hGal-1 and hGal-9, respectively .
    Galectin-3-IN-4
  • HY-148766
    VU661

    		Others Metabolic Disease
    VU661, a phenazine carboxamide, is a modulator of circadian rhythms to produce a period lengthening of the circadian rhythm. VU661 is a redox-active small molecule .
    VU661
  • HY-158987
    Adenosine phosphonobutyric, 2'(3'), 5'-diposphate

    APBADP

    		 Endogenous Metabolite Metabolic Disease
    Adenosine phosphonobutyric, 2'(3'), 5'-diposphate (APBADP) is a potent Bacillus subtilis and human adenylosuccinate lyase (ASL) inhibitor. Adenosine phosphonobutyric, 2'(3'), 5'-diposphate also is a competitive succinylaminoimidazole carboxamide ribotide (SAICAR) inhibitor .
    Adenosine phosphonobutyric, 2'(3'), 5'-diposphate
  • HY-17520R
    Penthiopyrad (Standard)

    		Fungal Infection
    Penthiopyrad (Standard) is the analytical standard of Penthiopyrad. This product is intended for research and analytical applications. Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
    Penthiopyrad (Standard)
  • HY-W017413
    (S)-Pyrrolidine-2-carboxamide hydrochloride

    		Amino Acid Derivatives Others
    (S)-Pyrrolidine-2-carboxamide hydrochloride is a proline derivative .
    (S)-Pyrrolidine-2-carboxamide hydrochloride
  • HY-41461R
    5-Amino-3H-imidazole-4-Carboxamide (Standard)

    		Endogenous Metabolite Others
    5-Amino-3H-imidazole-4-Carboxamide (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-Carboxamide. This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.
    5-Amino-3H-imidazole-4-Carboxamide (Standard)
  • HY-41461AR
    5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard)

    		Biochemical Assay Reagents Others
    5-Amino-3H-imidazole-4-carboxamide (hydrochloride) (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-carboxamide (hydrochloride). This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-carboxamide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard)
  • HY-133157
    FAICAR

    5-Formamidoimidazole-4-carboxamide ribotide

    		 DNA/RNA Synthesis Others
    FAICAR (5-Formamidoimidazole-4-carboxamide ribotide) is a purine nucleotide.
    FAICAR
  • HY-113472
    N-Methyl-4-pyridone-3-carboxamide

    		Drug Metabolite Others
    N-Methyl-4-pyridone-3-carboxamide is a metabolite of coffee pyridines .
    N-Methyl-4-pyridone-3-carboxamide
  • HY-13010
    Laquinimod
    2 Publications Verification

    ABR-215062

    		 NF-κB Apoptosis Inflammation/Immunology
    Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has?the?potential?for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases?research .
    Laquinimod
  • HY-W062904
    Laquinimod sodium

    ABR-215062 sodium

    		 NF-κB Apoptosis Neurological Disease Inflammation/Immunology
    Laquinimod (ABR-215062) sodium, an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod sodium reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod sodium has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research .
    Laquinimod sodium
  • HY-15736
    Sodium Channel inhibitor 1

    		Sodium Channel Neurological Disease
    Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment.
    Sodium Channel inhibitor 1
  • HY-118245
    APP-FUBINACA

    		Cannabinoid Receptor
    APP-FUBINACA is a cannabinoid receptor agonist and a derivative of phenylalaninamide-based indazole-3-carboxamide. APP-FUBINACA exhibits neurostimulatory effects .
    APP-FUBINACA
  • HY-41461
    5-Amino-3H-imidazole-4-Carboxamide
    1 Publications Verification

    5-Aminoimidazole-4-carboxamide; AICA

    		 Endogenous Metabolite Others
    5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.
    5-Amino-3H-imidazole-4-Carboxamide
  • HY-156021
    Antitubercular agent-40

    		Bacterial Infection
    Antitubercular agent-40 (compound 93) is a thieno[2,3-b]quinoline-2-carboxamide compound with potential antitubercular activity .
    Antitubercular agent-40
  • HY-13010R
    Laquinimod (Standard)

    		NF-κB Apoptosis Inflammation/Immunology
    Laquinimod (Standard) is the analytical standard of Laquinimod. This product is intended for research and analytical applications. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research .
    Laquinimod (Standard)
  • HY-41461A
    5-Amino-3H-imidazole-4-carboxamide hydrochloride
    1 Publications Verification

    5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride

    		 Biochemical Assay Reagents Others
    5-Amino-3H-imidazole-4-carboxamide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    5-Amino-3H-imidazole-4-carboxamide hydrochloride
  • HY-118699
    Indole-3-thio carboxamide

    		Fungal Infection
    Indole-3-thio carboxamide is an antifungal agent. Indole-3-thio carboxamide is a biotransformation product of Camalexin (HY-119502) by plant pathogenic fungi Botrytis cinerea .
    Indole-3-thio carboxamide
  • HY-13907
    TCS 359
    1 Publications Verification

    		 FLT3 Cancer
    TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM .
    TCS 359
  • HY-128337
    AN7973

    		Parasite Infection
    AN7973 is the 6-carboxamide benzoxaborole, blocks intracellular parasite development and inhibits Cryptosporidium growth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting agent candidate for treating cryptosporidiosis.
    AN7973
  • HY-106048
    Bredinin aglycone

    5-Hydroxy-1H-imidazole-4-carboxamide; SM-108

    		 Nucleoside Antimetabolite/Analog Others
    Bredinin aglycone (5-Hydroxy-1H-imidazole-4-carboxamide) is a purine nucleotide analogue. Bredinin aglycone can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogues .
    Bredinin aglycone
  • HY-119415
    Levovirin

    ICN-17261

    		 Others Others
    Levovirin (ICN-17261) is a potent 1-β-aminopyrazole-3-carboxamide that activates human T cells to secrete type 1 cytokines comparable to ribavirin. Levovirin shows promising immunomodulatory properties .
    Levovirin
  • HY-107981
    LSN 3213128
    1 Publications Verification

    		 Antifolate Cancer
    LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity .
    LSN 3213128
  • HY-152318
    Adenosine-2-carboxamide

    		Nucleoside Antimetabolite/Analog Others
    Adenosine-2-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Adenosine-2-carboxamide
  • HY-151938
    Reverse transcriptase-IN-3

    		HIV Infection
    Reverse transcriptase-IN-3 is a pyrimidine-5-carboxamide derivative, acts as an inhibitor of HIV-1. Reverse transcriptase-IN-3 shows potent activity against the HIV-1 wild-type and mutant strains .
    Reverse transcriptase-IN-3
  • HY-100162
    TOK-8801

    		Others Inflammation/Immunology
    TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.
    TOK-8801
  • HY-114570
    Tiazofurin

    NSC 286193; Riboxamide

    		 Nucleoside Antimetabolite/Analog Orthopoxvirus Infection Cancer
    Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) . Tiazofurin also has anti-orthopoxvirus and anti-variola activities .
    Tiazofurin
  • HY-W702068
    7-Hydroxygranisetron hydrochloride

    Metabolite D hydrochloride

    		 Biochemical Assay Reagents Others
    7-Hydroxy-1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide (Metabolite D) hydrochloride is a biological molecule.
    7-Hydroxygranisetron hydrochloride
  • HY-150252A
    ATIC-IN-1 acetate

    		Others Cancer
    ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
    ATIC-IN-1 acetate
  • HY-150252
    ATIC-IN-1

    		Others Cancer
    ATIC-IN-1(compound 14) is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
    ATIC-IN-1
  • HY-135830
    AHR antagonist 4

    		Aryl Hydrocarbon Receptor Cancer
    AHR antagonist 4 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and a potent aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 293, has an IC50 of 82.2 nM. AHR antagonist 4 has anti-cancer effects .
    AHR antagonist 4
  • HY-148038
    5-HT3 antagonist 5

    		5-HT Receptor Neurological Disease
    5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice .
    5-HT3 antagonist 5
  • HY-152685
    4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide

    		Nucleoside Antimetabolite/Analog Others
    4-Amino-1-(β-D-ribofurano syl)-7H-pyrrolo [2.3-d] pyrimidine-5-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide
  • HY-W956235
    (S,R,S)-AHPC-CO-C-piperazine

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(piperazin-1-yl)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is an E3 ligase ligand-linker conjugate.
    (S,R,S)-AHPC-CO-C-piperazine
  • HY-159487
    (S,R,S)-AHPC-CO-spiro[3.3]heptane-Ph-CHO

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-methoxyphenyl)spiro[3.3]heptane-2-carboxamido)-3,3-dimethylbutanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is an E3 ligase ligand-linker conjugate.
    (S,R,S)-AHPC-CO-spiro[3.3]heptane-Ph-CHO
  • HY-149082
    LTB4 antagonist 1

    		Leukotriene Receptor Inflammation/Immunology
    LTB4 antagonist 1, a carboxamide-acid compound, is a potent Leukotriene B4 (LTB4) antagonist with an IC50 of 288 nM. LTB4 antagonist 1 has significant anti-inflammatory properties .
    LTB4 antagonist 1
  • HY-149365
    SIKs-IN-1

    		Salt-inducible Kinase (SIK) Inflammation/Immunology
    SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, is a Salt-inducible kinases (SIKs) inhibitor. SIKs regulates the transformation of M1/M2 macrophages, involving in inflammation process. SIKs-IN-1 inhibits SIK activity, up-regulates anti-inflammatory cytokine IL-10, but down-regulates pro-inflammatory cytokine IL-12. SIKs-IN-1 shows excellent anti-inflammatory effects in a DSS-induced colitis model .
    SIKs-IN-1
  • HY-106628
    Sudoxicam

    		COX Inflammation/Immunology
    Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity .
    Sudoxicam
  • HY-149083
    LTB4 antagonist 2

    		Leukotriene Receptor Inflammation/Immunology
    LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM .
    LTB4 antagonist 2
  • HY-124260
    SB-204900

    		p38 MAPK Inflammation/Immunology
    SB-204900 is an oxane carboxamide that can be isolated from the hexane extract of Clausena lansium. SB-204900 significantly inhibited phosphorylation of p38 MAPK. SB-204900 has anti-inflammatory activity .
    SB-204900
  • HY-P4154
    Bevonescein

    ALM-488

    		 Fluorescent Dye Neurological Disease Cancer
    Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
    Bevonescein
  • HY-P1103A
    CTCE-9908 TFA

    		CXCR Cancer
    CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
    CTCE-9908 TFA
  • HY-P1103
    CTCE-9908
    1 Publications Verification

    		 CXCR Cancer
    CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
    CTCE-9908
  • HY-118911
    ATM Inhibitor-10

    		ATM/ATR Cancer
    ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors .
    ATM Inhibitor-10
  • HY-P2231A
    Cotadutide acetate
    1 Publications Verification

    MEDI0382 acetate

    		 GCGR Metabolic Disease
    Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
    Cotadutide acetate

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: