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Results for "

Lipolysis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (2) Adrenergic Receptor (3) AMPK (1) Antibiotic (2) AP-1 (1) Apoptosis (1) ATGL (1) Biochemical Assay Reagents (1) Calcium Channel (3) Carboxylesterase (1) Chemerin Receptor (1) COX (2) Cyclic GMP-AMP Synthase (3) Endogenous Metabolite (1) ERK (3) Free Fatty Acid Receptor (2) Glucocorticoid Receptor (1) GPR109A (4) Histone Methyltransferase (1) Lipase (2) Liposome (1) Melanocortin Receptor (2) Mitochondrial Metabolism (1) MMP (2) NF-κB (1) p38 MAPK (1) Phospholipase (1) PKA (4) PPAR (4) Reactive Oxygen Species (2) STAT (2) Thyroid Hormone Receptor (2) TNF Receptor (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (6) Endocrinology (3) Infection (3) Inflammation/Immunology (6) Metabolic Disease (36) Neurological Disease (2)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135982

GPR81 agonist 1 2 Publications Verification	GPR109A	Metabolic Disease
GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC₅₀s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a .

HY-P1210A

Lys-γ3-MSH(human) TFA	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-125096

C108297	Glucocorticoid Receptor	Metabolic Disease Inflammation/Immunology
C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding K_i 0.7 nM; GR reporter gene functional K_i 0.6 nM). C108297 attenuates obesity by reducing caloric intake and increasing lipolysis and fat oxidation, and in addition attenuates inflammation .

HY-B0283

Acipimox 1 Publications Verification K-9321	Others	Metabolic Disease
Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity .

HY-A0231

Glymidine sodium Gondafon; Glycodiazine	Others	Metabolic Disease
Glymidine sodium is an oral active antidiabetic. Glymidine sodium is the inhibitor of hepatic lipolysis. Glymidine sodium inhibits the glucose formation and supresses the elevated pyruvate oxidation which results from the inhibition of endogenous lipid mobilization .

HY-147501

TRβ agonist 3	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics .

HY-147500

TRβ agonist 2	Thyroid Hormone Receptor	Metabolic Disease
TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics .

HY-114754

BemPPOX	Lipase	Metabolic Disease
BemPPOX is an orally active, potent dog gastric lipase (DGL) inhibitor with X_l50 (the inhibitor molar excess leading to 50% lipase inhibition) of 0.5. BemPPOX is also a good inhibitor of GPLRP2 (x_l50=0.64). BemPPOX efficiently regulates the gastrointestinal lipolysis and slows down the overall lipolysis process in rats. BemPPOX has the potential for obesity research .

HY-P1210

Lys-γ3-MSH(human)	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-B0283A

Acipimox sodium K-9321 sodium	Others	Metabolic Disease
Acipimox (K-9321) sodium, a nicotinic acid analogue, is an antilipolytic compound. Acipimox sodium stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity .

HY-125254

LEI110	Phospholipase Others	Infection Metabolic Disease
LEI110 is a potent, selective and cell-permeable pan-inhibitor of the HRASLS family of thiol hydrolases. LEI110 inhibits PLA2G16, HRASLS2, RARRES3 and iNAT, with pIC₅₀ values of 7.0, 6.8, 6.8, and 7.6, respectively. LEI110 reduces cellular arachidonic acid levels and oleic acid-induced lipolysis in HepG2 cells .

HY-116771

CL 316243 free acid 5+ Cited Publications	Adrenergic Receptor	Metabolic Disease
CL316243 free acid is a highly potent selective β3-adrenoceptor agonist with a EC₅₀ of 3 nM, but is an extremely poor to β1/2- receptors. CL316243 free acid is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 free acid has the potential for the treatment obesity, diabetes and urge urinary incontinence .

HY-B0283R

Acipimox (Standard)	Others	Metabolic Disease
Acipimox (Standard) is the analytical standard of Acipimox. This product is intended for research and analytical applications. Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity .

HY-15859

Atglistatin Maximum Cited Publications 18 Publications Verification	ATGL	Metabolic Disease
Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor which inhibits lipolysis with an IC₅₀ of 0.7 μM in vitro.

HY-119006

L-640,033	Adrenergic Receptor	Endocrinology
L-640,033 is a potent agonist of β-adrenergic. L-640,033 play an important role in lipid metabolism, and growth .

HY-N4218

Saikosaponin B4	Others	Metabolic Disease
Saikosaponin B4 is a member of saikosaponins isolated from the roots of Bupleurum chinensis, selectively inhibits ACTH-induced lipolysis .

HY-19842

GS-9667 CVT 3619	Adenosine Receptor	Cardiovascular Disease Metabolic Disease
GS-9667 (CVT 3619), a novel N ⁶-5'-substituted adenosine analog, is a selective, partial agonist of the A₁ adenosine receptor (A₁AdoR). GS-9667 binds to adipocyte membranes with high (K_H=14 nM) and low (K_L=5.4 μM) affinities. GS-9667 reduces cyclic AMP content and release of nonesterified fatty acids from epididymal adipocytes with IC₅₀ values of 6 nM and 44 nM, respectively. GS-9667 inhibits lipolysis and has the potential for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA) .

HY-N4219

Saikosaponin B3	Others	Neurological Disease Metabolic Disease
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells .

HY-120602

WWL229	Carboxylesterase	Metabolic Disease
WWL229 is a selective inhibitor of carboxylesterase 3 (Ces3) with an IC₅₀ of 1.94 µM. WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis .

HY-107737

1,2-DLPC 1 Publications Verification 1,2-Dilauroyl-sn-glycero-3-phosphocholine	Liposome Apoptosis TNF Receptor PPAR	Metabolic Disease
1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells .

HY-N11924

Foenumoside B	AMPK PPAR	Metabolic Disease
Foenumoside B is a triterpene saponin isolated from Lysimachia foenum-graecum. Foenumoside B activates AMPK signaling, inhibits PPARγ-induced adipogenesis, and shifts lipid metabolism toward lipolysis. Foenumoside B can be used in the study of obesity and obesity-related metabolic diseases .

HY-153813

Z16078526	p38 MAPK Mitochondrial Metabolism	Others
Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse .

HY-W016868

3-Chloro-5-hydroxybenzoic acid	Others	Metabolic Disease
3-Chloro-5-hydroxybenzoic acid is a potent, orally active and selective lactate receptor GPR81 agonist, with an EC₅₀ of 16 μM for human GPR81. 3-Chloro-5-hydroxybenzoic acid exhibits favorable in vivo effects on lipolysis in a mouse model of obesity .

HY-119741

Salacinol	Lipase	Metabolic Disease
Salacinol can be isolated from the roots of the plant Salacia reticulata. Salacinol inhibits fat metabolizing enzymes, such as pancreatic lipase (PL, IC₅₀=12.6 mg/L), lipoprotein lipase (LPL, IC₅₀=13.6 mg/L), and glycerophosphate dehydrogenase (GPDH), enhances the lipolysis, and exhibits antiobesity efficacy in rats .

HY-47823

GPCR agonist-2	GPR109A	Metabolic Disease
GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC₅₀ value of 6.51. GPCR agonist-2 can be used for research of lipid disorders .

HY-114011

AMG7703	Free Fatty Acid Receptor	Metabolic Disease Inflammation/Immunology
AMG7703 is a selective and allosteric agonists of FFA2 (GPR43), the receptor for short-chain fatty acids (SCFAs), acetate, and propionate. AMG7703 can be used to research for in inflammatory and metabolic .

HY-N0236

Corylin 5 Publications Verification	Antibiotic STAT	Infection Metabolic Disease Cancer
Corylin is an orally active flavonoid anti-inflammatory and osteogenic agent that inhibits IL-6-induced STAT3 promoter activity and STAT3 phosphorylation. Corylin also has anticancer, antiatherosclerotic, and ameliorating activity in hyperlipidemia and insulin resistance, inducing adipocyte browning and lipolysis through SIRT1 or β3-AR-dependent pathways .

HY-116771A

CL 316243 5+ Cited Publications	Adrenergic Receptor	Metabolic Disease
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC₅₀ of 3 nM, but is an extremely poor to β1/2- receptors .CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate . CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence .

HY-165047

1-Palmitoyl-2-linoleoyl-3-stearoyl-rac-glycerol 1-Palmitin-2-linolein-3-stearin; 16:0/18:2/18:0-TG; TG(16:0/18:2/18:0)	Others	Others
1-Palmitoyl-2-linoleoyl-3-stearoyl-rac-glycerol (1-Palmitin-2-linolein-3-stearin) is a compound that is being studied for lipid properties in human milk and infant formula. Although human milk has larger fat globules, it has a higher rate of gastrointestinal lipolysis, which may be related to the milk fat globule membrane (MFGM).

HY-111952

SR-4995 CID 16016685	Endogenous Metabolite	Others
SR-4995 (CID 16016685) is a highly effective and selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), facilitating the activation of adipose triglyceride lipase (ATGL) by displacing ABHD5 from its inhibitory regulators, perilipin-1 (PLIN1) and PLIN5. It directly interacts with ABHD5, inhibiting its association with PLIN1, and promotes lipolysis in adipocytes and muscle tissues while circumventing PKA-dependent signaling pathways.

HY-119222

GSK256073 2 Publications Verification	GPR109A	Metabolic Disease
GSK256073 is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC₅₀ of 7.5 (human HCA2). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia . GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2

HY-N0236R

Corylin (Standard)	Antibiotic STAT	Infection Metabolic Disease Cancer
Corylin (Standard) is the analytical standard of Corylin. This product is intended for research and analytical applications. Corylin is an orally active flavonoid anti-inflammatory and osteogenic agent that inhibits IL-6-induced STAT3 promoter activity and STAT3 phosphorylation. Corylin also has anticancer, antiatherosclerotic, and ameliorating activity in hyperlipidemia and insulin resistance, inducing adipocyte browning and lipolysis through SIRT1 or β3-AR-dependent pathways .

HY-119222A

GSK256073 tris	GPR109A	Metabolic Disease
GSK256073 tris is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC₅₀ of 7.5 (human HCA2). GSK256073 tris acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia . GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2

HY-121140

AZ1729	Free Fatty Acid Receptor	Metabolic Disease
AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in G_i-mediated pathways, but not at those transduced by G_q/G₁₁. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2 .

HY-123468

HA-1004	Cyclic GMP-AMP Synthase PKA ERK Calcium Channel	Cardiovascular Disease Metabolic Disease
HA-1004 is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 is an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models .

HY-P2712

Chemerin-9, mouse Chemerin148–156, mouse	Chemerin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC₅₀ = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC₅₀ = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis .

HY-123468A

HA-1004 di(hydrochloride)	Cyclic GMP-AMP Synthase PKA ERK Calcium Channel	Cardiovascular Disease Metabolic Disease
HA-1004 dihydrochloride is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 dihydrochloride is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 dihydrochloride is an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models .

HY-112348

HA-1004 hydrochloride	Cyclic GMP-AMP Synthase PKA ERK Calcium Channel	Cardiovascular Disease Metabolic Disease
HA-1004 hydrochloride is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 hydrochloride is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein (Cyclic GMP-AMP Synthase), and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 hydrochloride an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models .

HY-139058

23-epi-26-Deoxyactein 27-Deoxyactein	PPAR	Metabolic Disease Cancer
23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound .

HY-139058R

23-epi-26-Deoxyactein (Standard)	PPAR	Metabolic Disease Cancer
23-epi-26-Deoxyactein (Standard) is the analytical standard of 23-epi-26-Deoxyactein. This product is intended for research and analytical applications. 23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound .

HY-107574

TC-E 5003	Histone Methyltransferase AP-1 NF-κB PKA	Metabolic Disease Inflammation/Immunology Cancer
TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC₅₀ of 1.5 µM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers .

HY-114911

Feprazone DA2370; Prenazone; Zepelin	COX Reactive Oxygen Species MMP	Inflammation/Immunology
Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity .

HY-113058

3-Hydroxyoctanoic acid	Biochemical Assay Reagents	Others
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

HY-19310

AMP-579	Adenosine Receptor	Cardiovascular Disease Metabolic Disease
AMP-579 is an adenosine receptor agonist that primarily targets adenosine A1 and A2_A receptors (with K_i values of 1.7 and 4.5 nM for the A1 receptor in rat brain and adipocytes, and a K_i value of 56 nM for the A2_A receptor in rat brain). AMP-579 inhibits lipolysis, restores insulin-dependent glucose transport, and reduces heart rate through the activation of A1 receptors, while it induces vasodilation, particularly in coronary arteries, through the activation of A2_A receptors (with an IC₅₀ of 0.3 μM in porcine coronary arterial rings). AMP 579 shows potential for application in cardioprotection and the treatment of acute myocardial infarction .

HY-114911R

Feprazone (Standard)	COX Reactive Oxygen Species MMP	Inflammation/Immunology
Feprazone (Standard) is the analytical standard of Feprazone. This product is intended for research and analytical applications. Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity .

Cat. No.	Product Name	Type

HY-107737

1,2-DLPC 1 Publications Verification 1,2-Dilauroyl-sn-glycero-3-phosphocholine	Drug Delivery
1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells .

HY-113058

3-Hydroxyoctanoic acid

Biochemical Assay Reagents

3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.

Cat. No.	Product Name	Target	Research Area

HY-P1210A

Lys-γ3-MSH(human) TFA	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P3650

Cholecystokinin (1-21) CCK-1-21	Peptides	Metabolic Disease
Cholecystokinin (1-21) (CCK-1-21) is a cholecystokinin (CCK) fragment. Cholecystokinin (1-21) stimulates lipolysis in human adipose tissue .

HY-P1210

Lys-γ3-MSH(human)	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P2712

Chemerin-9, mouse Chemerin148–156, mouse	Chemerin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC₅₀ = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC₅₀ = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis .

Cat. No.	Product Name		Classification

HY-107737

1,2-DLPC 1 Publications Verification 1,2-Dilauroyl-sn-glycero-3-phosphocholine		Phospholipids
1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells .

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