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NADH

" in MedChemExpress (MCE) Product Catalog:

60

Inhibitors & Agonists

3

Fluorescent Dye

2

Biochemical Assay Reagents

1

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20

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7

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3

Isotope-Labeled Compounds

6

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-F0001
    NADH disodium salt
    4 Publications Verification

    Disodium NADH

    Endogenous Metabolite Metabolic Disease
    NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
    NADH disodium salt
  • HY-146036

    Endogenous Metabolite Metabolic Disease
    NADH-IN-1 has NADH:ubiquinone oxidoreductase inhibitory activity with an IC50 value of 27 μM. NADH-IN-1 can effectively stimulate glucose uptake in vitro. NADH-IN-1 is readily metabolised by the liver. NADH-IN-1 can be used for researching diabetes .
    NADH-IN-1
  • HY-P2807

    LAD

    Endogenous Metabolite Inflammation/Immunology Cancer
    L-Lactate dehydrogenase, Microorganism (LAD) is a redox enzyme. L-Lactate dehydrogenase catalyzes the reduction of pyruvate to L-lactate by NADH in vivo with absolute enantiospecificity .
    L-Lactate dehydrogenase, Microorganism
  • HY-113355

    Endogenous Metabolite Metabolic Disease
    NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
    NADH
  • HY-F0001A

    Disodium NADH hydrate

    Endogenous Metabolite Metabolic Disease
    NADH disodium salt (Disodium NADH) hydrate is an orally active reduced coenzyme. NADH disodium salt hydrate is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt hydrate plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
    NADH disodium hydrate
  • HY-168146

    Endogenous Metabolite Cancer
    NADH-IN-2 (compund 8) is a Type II NADH dehydrogenase inhibitor .
    NADH-IN-2
  • HY-P3182

    Others Others
    NADH oxidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    NADH oxidase
  • HY-142098

    Reactive Oxygen Species Others
    3′-Hydroxy-4′-O-methylglabridin is an antioxidant that is effective at preventing NADH-dependent peroxidation .
    3′-Hydroxy-4′-O-methylglabridin
  • HY-159118

    Bacterial Infection
    PC-Qz1 is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor with an IC50 of 470 nM. PC-Qz1 has antibacterial activity .
    PC-Qz1
  • HY-155023

    Apoptosis Reactive Oxygen Species Cancer
    Apoptosis inducer 13 (Compound Ru4) can induce cancer cell apoptosis, and inhibits cancer cell migration and invasion. Apoptosis inducer 13 converts coenzyme NADH to NAD +, and increases intracellular ROS levels .
    Apoptosis inducer 13
  • HY-P2807K

    Endogenous Metabolite Metabolic Disease
    L-Lactate Dehydrogenase, bovine muscle is an oxidoreductase. L-Lactate Dehydrogenase, bovine muscle catalyzes the reversible conversion of lactate to pyruvate with the reduction of NAD+ to NADH .
    L-Lactate Dehydrogenase, bovine muscle
  • HY-145985

    Bacterial Infection
    CBR-3465 is a mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase inhibitor, with the MIC of 0.16 μM against Mtb .
    CBR-3465
  • HY-145986

    Bacterial Infection
    CBR-6672 is a mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase inhibitor, with the MIC of 0.14 μM against Mtb .
    CBR-6672
  • HY-13675

    NV-143

    Endogenous Metabolite Cancer
    ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo .
    ME-143
  • HY-113128S

    Isotope-Labeled Compounds Metabolic Disease
    sn-Glycerol 3-phosphate- 13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .
    sn-Glycerol 3-phosphate-13C3 disodium
  • HY-B0817

    Parasite Infection
    Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .
    Pyridaben
  • HY-B0817R

    Parasite Infection
    Pyridaben (Standard) is the analytical standard of Pyridaben. This product is intended for research and analytical applications. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .
    Pyridaben (Standard)
  • HY-N10184

    FKI-0550

    Others Infection
    Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC50 value of 5.1 μM against Ascaris suum NADH-fumarate reductase .
    Paecilaminol
  • HY-125778

    Others Metabolic Disease
    Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.
    Cochlioquinone B
  • HY-160644

    Bacterial Infection
    8PC is a the ligand of InhA-NADH-JPM, and can be used for study of tuberculosis .
    8PC
  • HY-N12214

    Reactive Oxygen Species Inflammation/Immunology
    Sartorypyrone D is a NADH-fumarate reductase inhibitor that can be produced by Neosartorya fischeri FO-5897 .
    Sartorypyrone D
  • HY-B0445A
    NAD sodium
    Maximum Cited Publications
    24 Publications Verification

    β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium

    Endogenous Metabolite Metabolic Disease
    NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .
    NAD sodium
  • HY-P2800A

    Endogenous Metabolite Metabolic Disease
    Diaphorase from Clostridium sp. is responsible for catalyzing the oxidation of NADH or NADPH and is involved in regulating cellular energy metabolism .
    Diaphorase, clostridium sp.
  • HY-142099

    Reactive Oxygen Species Others
    Hispaglabridin A is an antioxidant that is effective at inhibiting lipid peroxidation .
    Hispaglabridin A
  • HY-126253
    BI-4916
    4 Publications Verification

    Phosphoglycerate Dehydrogenase (PHGDH) Cancer
    BI-4916 is a proagent of BI-4924. BI-4924 is a NADH/NAD +-competitive PHGDH inhibitor .
    BI-4916
  • HY-P3186

    Endogenous Metabolite Metabolic Disease
    Glucose dehydrogenase, recombinant Microorganisms is a oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP + to NADPH or, to a lesser extent, NAD + to NADH. Glucose dehydrogenase (GDH) accepts both NAD + and NADP + as cofactors and can be used for the regeneration of NADH and NADPH .
    Glucose dehydrogenase, recombinant Microorganisms
  • HY-133965

    Others Inflammation/Immunology
    Cinchonain IIa is an antioxidant agent with EC50s of 6.8 μM and 26.5 μM for DPPH and PMS-NADH .
    Cinchonain IIa
  • HY-120338

    Mitochondrial Metabolism Parasite Infection
    RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor .
    RYL-552
  • HY-113128

    Endogenous Metabolite Others
    sn-Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.
    sn-Glycerol 3-phosphate
  • HY-163034

    Apoptosis Reactive Oxygen Species Cancer
    Antitumor photosensitizer-5 (Ru2) is a photosensitizer which effectively target tumor mitochondria with an IC50 of 0.3 μM for phototoxicity to A549 cells. Under 460 nm light irradiation, antitumor photosensitizer-5 induces the generation of reactive oxygen species and NADH depletion, causes mitochondrial damage and activation of caspase-3, inducing apoptosis and suppressing cell migration. Antitumor photosensitizer-5 has the potential to prevent the growth of malignant tumors, therefore, shows the potential to be applied to photodynamic therapy .
    Antitumor photosensitizer-5
  • HY-113128B

    Endogenous Metabolite Metabolic Disease
    sn-Glycerol 3-phosphate biscyclohexylammonium salt is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.
    sn-Glycerol 3-phosphate biscyclohexylammonium salt
  • HY-113128A

    Endogenous Metabolite Metabolic Disease
    sn-Glycerol 3-phosphate lithium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.
    sn-Glycerol 3-phosphate lithium
  • HY-114936
    Piericidin A
    1 Publications Verification

    AR-054

    Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism Infection Neurological Disease Cancer
    Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .
    Piericidin A
  • HY-N7151

    Antibiotic Bacterial Fungal Infection
    Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles .
    Aurachin D
  • HY-Z0031

    Endogenous Metabolite Metabolic Disease
    (R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes .
    (R)-(-)-1,2-Propanediol
  • HY-P3185

    Endogenous Metabolite Metabolic Disease
    beta-Galactose dehydrogenase can make conversion of galactose to galactonolactone and the concomitant reduction of NAD to the fluorescent NADH. beta-Galactose dehydrogenase can be used for the determination of galactose .
    beta-Galactose dehydrogenase
  • HY-125921

    Fluorescent Dye Others
    WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM .
    WST-3
  • HY-147124

    IFNAR Infection Cancer
    RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression .
    RIG012
  • HY-158421

    Oxidative Phosphorylation Mitochondrial Metabolism Cancer
    MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect .
    MS-L6
  • HY-B0860

    Others Cancer
    Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.
    Diuron
  • HY-119419S

    Cholinesterase (ChE) Parasite Isotope-Labeled Compounds Others
    Pirimicarb-d6 is the deuterium labeled Diuron. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male
    Pirimicarb-d6
  • HY-P2996

    Others Others
    NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
    NAD(P)H-Nitrate reductase
  • HY-145499

    Fluorescent Dye Others
    XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.
    XTT sodium hydrate
  • HY-157744

    Others Cancer
    Coumarin–quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases which consists of a coumarin fluorophore and a ubiquinone analog. Coumarin–quinone conjugate can be used to measure the kinetic parameters of AIFM2/FSP1 for researches such as ferroptosis .
    Coumarin–quinone conjugate
  • HY-117420

    Sigma Receptor Cancer
    CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD +/NADH, and ATP levels, and decreases the concentration of ROS .
    CM764
  • HY-117897

    Parasite Infection
    CK-2-68 is an inhibitor for complex III in protozoan mitochondrial respiratory chain, by targeting the alternative NADH dehydrogenase (NDH2) of the malarial parasite Plasmodium. CK-2-68 exhibits antimalaria efficacy, that inhibits Plasmodium falciparum infected erythrocytes with an IC50 of 40 nM .
    CK-2-68
  • HY-161685

    Bacterial Reactive Oxygen Species Endogenous Metabolite Infection
    Antibiofilm agent-8 (compound Ru2) enhances antimicrobial activity on visible-light exposure (400-700 nm, 10 J cm-2). Antibiofilm agent-8 generates of oxidative stress via NADH oxidation and ROS generation and compromises bacterial wall .
    Antibiofilm agent-8
  • HY-B0860R

    Others Cancer
    Diuron (Standard) is the analytical standard of Diuron. This product is intended for research and analytical applications. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.
    Diuron (Standard)
  • HY-151941

    Bacterial Infection
    MtInhA-IN-1 is a selective and orally active Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhibitor with an IC50 of 0.23 μM. MtInhA-IN-1 potently against M. tuberculosis H37Rv strain with a MIC value of 0.4 μM .
    MtInhA-IN-1
  • HY-136976
    WST-1
    2 Publications Verification

    Fluorescent Dye Cancer
    WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm .
    WST-1

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