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Results for "

ND

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) Acetyl-CoA Carboxylase (3) Androgen Receptor (1) Antibiotic (1) Apoptosis (4) ATTECs (1) Bacterial (3) Biochemical Assay Reagents (3) c-Kit (1) Calcium Channel (3) COX (1) Cytochrome P450 (2) Dipeptidyl Peptidase (1) Drug Metabolite (1) Endogenous Metabolite (27) Ferroptosis (2) FGFR (1) Fluorescent Dye (2) G-quadruplex (1) HBV (1) Histone Methyltransferase (2) HIV (2) iGluR (6) IRAK (2) Isotope-Labeled Compounds (45) Mitochondrial Metabolism (1) MMP (4) mTOR (1) NO Synthase (1) NOD-like Receptor (NLR) (1) p97 (1) Parasite (1) PDGFR (1) Phosphodiesterase (PDE) (2) Progesterone Receptor (1) PROTACs (1) RET (1) Reverse Transcriptase (2) Small Interfering RNA (siRNA) (8) VEGFR (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (6) Endocrinology (2) Infection (6) Inflammation/Immunology (3) Metabolic Disease (10) Neurological Disease (11)
Oligonucleotides:	Human Pre-designed siRNA Sets (7) siRNAs (7)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124939

ND-322 hydrochloride	MMP	Cancer
ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination .

HY-155107

ND-011992	Mitochondrial Metabolism Bacterial	Infection
ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo₃ oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21Δcyo with the IC₅₀* of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study .

HY-124373

ND-336	MMP	Metabolic Disease
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14, with K_is of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound .

HY-101842

ND-646 10+ Cited Publications	Acetyl-CoA Carboxylase	Cancer
ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC₅₀s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.

HY-16901

Firsocostat Maximum Cited Publications 18 Publications Verification ND-630; GS-0976; NDI-010976	Acetyl-CoA Carboxylase	Metabolic Disease
Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC₅₀ values of 2.1 and 6.1 nM, respectively.

HY-16901A

Firsocostat (S enantiomer) ND-630 (S enantiomer); GS-0976 (S enantiomer); NDI-010976 (S enantiomer)	Acetyl-CoA Carboxylase	Others
Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase (ACC) inhibitor.

HY-120041

ND-2158	IRAK	Cancer
ND-2158 is a competitive IRAK4 inhibitor, with the K_i of 1.3 nM. ND-2158 suppresses LPS-induced TNF production in human white blood cells, alleviated collagen-induced arthritis, and blocked gout formation in mouse models. ND-2158 has antitumor activity in vivo .

HY-117622

ND-2110	IRAK	Inflammation/Immunology Cancer
ND-2110 is a selective IRAK4 inhibitor (K_i: 7.5 nM). ND-2110 binds to the ATP pocket of IRAK4. ND-2110 targets the subset of activated B cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL) cell lines with MYD88 L265P mutations,. ND-2110 inhibits LPS-induced TNF production, alleviates collagen-induced arthritis, and blocks gout formation in mouse models .

HY-124341

ND-378	MMP	Neurological Disease
ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a K_i value of 230 nM. ND-378 can be used to study spinal cord injury (SCI) .

HY-P5559

ND1-YL2	PROTACs	Cancer
ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .

HY-170674A

ND-L11B TFA	Histone Methyltransferase	Cancer
ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with the DC₅₀ of 1.48 and 0.8 μM, the D_max is closed to 80 % .

HY-170674

ND-L11B free base	Histone Methyltransferase	Cancer
ND-L11B is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with the DC₅₀ of 1.48 and 0.8 μM, the D_max is closed to 80 % .

HY-135331S

N-Desmethyl-Apalutamide-15N,d4	Isotope-Labeled Compounds Androgen Receptor Cytochrome P450	Cancer
N-Desmethyl-Apalutamide-15N,d4 is the ¹⁵N and deuterium labeled isotope of N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration .

HY-124373A

(R)-ND-336	MMP	Metabolic Disease
(R)-ND-336 is a potent and selective MMP-9 inhibitor with a K_i of 19 nM. (R)-ND-336 inhibits MMP-2 (K_i=127 nM) and MMP-14 (K_i=119 nM). (R)-ND-336 has the potential for diabetic foot ulcers (DFUs) research .

HY-162588

MC-ND-18	ATTECs NOD-like Receptor (NLR)	Inflammation/Immunology
MC-ND-18 is an ATTEC degrader of NLRP3 through autophagic mechanisms, with the DC₅₀ of 125.5 nM in THP-1 cell. MC-ND-18 is composed of a NLRP3 ligand, linker and LC3 ligand .

HY-RS16307

mt-Nd4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Neurological Disease Metabolic Disease
mt-Nd4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for mt-Nd4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components mt-Nd4 Mouse Pre-designed siRNA Set A-1 mt-Nd4 Mouse Pre-designed siRNA Set A-2 mt-Nd4 Mouse Pre-designed siRNA Set A-3 siRNA Negative Control FAM-labeled siRNA Negative Control GAPDH Positive Control siRNA (Mouse)

mt-Nd4 Mouse Pre-designed siRNA Set A mt-Nd4 Mouse Pre-designed siRNA Set A

HY-RS08801

MT-ND5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND5 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND5 Human Pre-designed siRNA Set A MT-ND5 Human Pre-designed siRNA Set A

HY-RS08797

MT-ND2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND2 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND2 Human Pre-designed siRNA Set A MT-ND2 Human Pre-designed siRNA Set A

HY-RS08796

MT-ND1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND1 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND1 Human Pre-designed siRNA Set A MT-ND1 Human Pre-designed siRNA Set A

HY-RS08799

MT-ND4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND4 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND4 Human Pre-designed siRNA Set A MT-ND4 Human Pre-designed siRNA Set A

HY-RS08798

MT-ND3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND3 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND3 Human Pre-designed siRNA Set A MT-ND3 Human Pre-designed siRNA Set A

HY-RS08802

MT-ND6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND6 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND6 Human Pre-designed siRNA Set A MT-ND6 Human Pre-designed siRNA Set A

HY-RS08800

MT-ND4L Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MT-ND4L Human Pre-designed siRNA Set A contains three designed siRNAs for MT-ND4L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-ND4L Human Pre-designed siRNA Set A MT-ND4L Human Pre-designed siRNA Set A

HY-148012

SOP1812 QN-302	G-quadruplex	Cancer
SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with anti-tumor activity. SOP1812 binds to quadruplex arrangements (G4s), and down-regulates several cancer gene pathways. SOP1812 shows great affinity to hTERT G4 and HuTel21 G4 with K_D values of 4.9 and 28.4 nM, respectively. SOP1812 can be used for the research of cancer .

HY-A0042S2

Rufinamide-15N,d2-1 CGP 33101-¹⁵N,d₂-1; E 2080-¹⁵N,d₂-1; RUF 331-¹⁵N,d₂-1	Isotope-Labeled Compounds	Neurological Disease
Rufinamide- ¹⁵N,d₂-1 (CGP 33101- ¹⁵N,d₂-1; E 2080- ¹⁵N,d₂-1; RUF 331- ¹⁵N,d₂-1) is ¹⁵N- and deuterium-labeled Rufinamide (HY-A0042) .

HY-B0782S2

Acetazolamide-15N,d3	Isotope-Labeled Compounds	Others
Acetazolamide- ¹⁵N,d3 is the ¹⁵N and deuterium labeled isotope of Acetazolamide( ¹⁵N,d3) .

HY-W727879

Upadacitinib-15N,d2 1 Publications Verification ABT-494-¹⁵N,d₂	Isotope-Labeled Compounds	Others
Upadacitinib- ¹⁵N,d₂ (ABT-494- ¹⁵N,d₂) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- ¹⁵N,d₂ (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC₅₀=43 nM). Upadacitinib- ¹⁵N,d₂ (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- ¹⁵N,d₂ (ABT-494) can be used for several autoimmune disorders research .

HY-17605S

Bictegravir-15N,d2	Isotope-Labeled Compounds	Infection
Bictegravir- ¹⁵N,d₂ (GS-9883- ¹⁵N,d₂) is the ¹⁵N and deuterium labeled Bictegravir (HY-17605) . Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC₅₀ of 7.5 nM .

HY-154754S

Saxagliptin Metabolite-15N,d2 hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin Metabolite- ¹⁵N,d₂ hydrochloride is ¹⁵N and deuterated labeled Saxagliptin Metabolite.

HY-129242S

Tempone-15N,d16 4-Oxo-Tempo-¹⁵N,d₁₆	Isotope-Labeled Compounds	Others
Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone[1].

HY-143785S

rel-Saxagliptin-15N,d2 hydrochloride	Isotope-Labeled Compounds	Others
rel-Saxagliptin- ¹⁵N,d₂ hydrochloride is the deuterium and ¹⁵N labeled Saxagliptin[1].

HY-147737S

Ammonium-15N,d4 chloride	Isotope-Labeled Compounds	Others
Ammonium- ¹⁵N,d₄ (chloride) is the deuterium and ¹⁵N labeled Ammonium chloride[1].

HY-W105664S

Aurinamide-15N,d2 hydrochloride	Isotope-Labeled Compounds	Others
Aurinamide- ¹⁵N,d₂ (hydrochloride) is a ¹⁵N-labeled and deuterium labeled Aurinamide[1].

HY-W008440S

DL-Cycloserine-15N,d3	Isotope-Labeled Compounds	Others
DL-Cycloserine- ¹⁵N,d₃ is the deuterium labeled DL-Cycloserine (HY-W008440) .

HY-148122

NW 1028	p97	Cancer
NW 1028 is a potent VCP/p97 inhibitor. NW 1028 targets the ND1L domain of p97 and inhibits the degradation of a p97-dependent reporter. NW 1028 has good binding affinity with K_d values of 100 and 285 nM for ND1L and full length p97, respectively. NW 1028 has the function of regulating the mitotic spindle of cells .

HY-144250S

Glycyl-L-proline-15N,d2 trifluoroacetate	Isotope-Labeled Compounds	Others
Glycyl-L-proline- ¹⁵N,d₂ (trifluoroacetate) is a ¹⁵N-labeled and deuterium labeled Glycyl-L-proline[1].

HY-N0486S13

L-Leucine-15N,d10	mTOR Endogenous Metabolite	Metabolic Disease
L-Leucine- ¹⁵N,d₁₀ is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

HY-B1462S2

Chlorzoxazone-13C,15N,d2	Cytochrome P450 Isotope-Labeled Compounds	Inflammation/Immunology
Chlorzoxazone- ¹³C, ¹⁵N,d₂ is ¹³C-, ¹⁵N-, and deuterium-labeled Chlorzoxazone (HY-B1462) .

HY-10285S

Saxagliptin-15N,d2 hydrochloride BMS-477118-¹⁵N,d₂ Hydrochloride	Isotope-Labeled Compounds Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin-15N,d2 Hydrochloride (BMS-477118-15N,d2 Hydrochloride) is the ¹⁵N and deuterium labeled isotope of Saxagliptin (HY-10285). Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-W106835S1

N-(3-Hydroxybenzyl)adenosine-15N,d2	Isotope-Labeled Compounds	Others
N-(3-Hydroxybenzyl)adenosine- ¹⁵N,d₂ is ¹⁵N and deuterium labeled N-(3-Hydroxybenzyl)adenosine .

HY-W016221S1

6-Hydroxy Chlorzoxazone-15N,d2	Isotope-Labeled Compounds Drug Metabolite	Others
6-Hydroxy Chlorzoxazone- ¹⁵N,d₂ is the ¹⁵N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221) .

HY-N0717S9

L-Valine-15N,d8	Isotope-Labeled Compounds	Others
L-Valine- ¹⁵N,d₈ is the deuterium and 15 N labeled L-Valine[1]. L-Valine (Valine) is a new nonlinear semiorganic material[2].

HY-N0666S9

L-Aspartic acid-15N,d3	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
L-Aspartic acid- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

HY-N0771S7

L-Isoleucine-15N,d10	Endogenous Metabolite	Others
L-Isoleucine- ¹⁵N,d₁₀ is the deuterium and ¹⁵N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

HY-N0326S9

L-Methionine-15N,d8	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Methionine- ¹⁵N,d₈ is the deuterium and ¹⁵N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

HY-Y0252S7

L-Proline-15N,d7	Endogenous Metabolite	Others
L-Proline- ¹⁵N,d₇ is the deuterium and ¹⁵N labeled L-Proline[1]. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0473S11

L-Tyrosine-15N,d7	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹⁵N,d₇ is the deuterium and ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0658S4

L-Threonine-15N,d5	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Threonine- ¹⁵N,d₅ is the deuterium and ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

HY-N0666S5

L-Aspartic acid-13C4,15N,d3	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
L-Aspartic acid- ¹³C₄, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

HY-17436S4

Clevidipine-15N,d10	Calcium Channel Isotope-Labeled Compounds	Cardiovascular Disease Cancer
Clevidipine- ¹⁵N,d₁₀ is ¹⁵N and deuterated labeled Clevidipine (HY-17436). Clevidipine is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H)=-40 mV ).

Cat. No.	Product Name	Type

HY-D2738

BP Fluor 532 NHS ester

Fluorescent Dyes/Probes

BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.

HY-D2763

BP Fluor 532 maleimide

Fluorescent Dyes/Probes

BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

Cat. No.	Product Name	Type

HY-W009022

Diantipyrylmethane	Indicators
Diantipyrylmethane is a chromogenic agent commonly used in spectrophotometry and extraction photometry for the determination of metals such as Au(III), Ti(IV), Ir, Fe(III), Mo, Nd, U(IV), Ir, Pt, and Re. Diantipyrylmethane is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W017567

Ethyl (E)-2-hexenoate trans-2-Hexenoic Acid Ethyl Ester	Drug Delivery
Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.

HY-75070

(+)-1-(1-Naphthyl)ethylamine

Biochemical Assay Reagents

(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

Cat. No.	Product Name	Target	Research Area

HY-P5559

ND1-YL2	PROTACs	Cancer
ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .

Cat. No.	Product Name	Chemical Structure

HY-W727879

Upadacitinib-15N,d2

1 Publications Verification

Upadacitinib- ¹⁵N,d₂ (ABT-494- ¹⁵N,d₂) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- ¹⁵N,d₂ (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC₅₀=43 nM). Upadacitinib- ¹⁵N,d₂ (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- ¹⁵N,d₂ (ABT-494) can be used for several autoimmune disorders research .

HY-17605S

Bictegravir-15N,d2
Bictegravir- ¹⁵N,d₂ (GS-9883- ¹⁵N,d₂) is the ¹⁵N and deuterium labeled Bictegravir (HY-17605) . Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC₅₀ of 7.5 nM .

HY-129242S

Tempone-15N,d16
Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone[1].

HY-135331S

N-Desmethyl-Apalutamide-15N,d4

N-Desmethyl-Apalutamide-15N,d4 is the ¹⁵N and deuterium labeled isotope of N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration .

HY-A0042S2

Rufinamide-15N,d2-1
Rufinamide- ¹⁵N,d₂-1 (CGP 33101- ¹⁵N,d₂-1; E 2080- ¹⁵N,d₂-1; RUF 331- ¹⁵N,d₂-1) is ¹⁵N- and deuterium-labeled Rufinamide (HY-A0042) .

HY-B0782S2

Acetazolamide-15N,d3
Acetazolamide- ¹⁵N,d3 is the ¹⁵N and deuterium labeled isotope of Acetazolamide( ¹⁵N,d3) .

HY-154754S

Saxagliptin Metabolite-15N,d2 hydrochloride
Saxagliptin Metabolite- ¹⁵N,d₂ hydrochloride is ¹⁵N and deuterated labeled Saxagliptin Metabolite.

HY-143785S

rel-Saxagliptin-15N,d2 hydrochloride
rel-Saxagliptin- ¹⁵N,d₂ hydrochloride is the deuterium and ¹⁵N labeled Saxagliptin[1].

HY-147737S

Ammonium-15N,d4 chloride
Ammonium- ¹⁵N,d₄ (chloride) is the deuterium and ¹⁵N labeled Ammonium chloride[1].

HY-W105664S

Aurinamide-15N,d2 hydrochloride
Aurinamide- ¹⁵N,d₂ (hydrochloride) is a ¹⁵N-labeled and deuterium labeled Aurinamide[1].

HY-W008440S

DL-Cycloserine-15N,d3
DL-Cycloserine- ¹⁵N,d₃ is the deuterium labeled DL-Cycloserine (HY-W008440) .

HY-144250S

Glycyl-L-proline-15N,d2 trifluoroacetate
Glycyl-L-proline- ¹⁵N,d₂ (trifluoroacetate) is a ¹⁵N-labeled and deuterium labeled Glycyl-L-proline[1].

HY-N0486S13

L-Leucine-15N,d10
L-Leucine- ¹⁵N,d₁₀ is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

HY-B1462S2

Chlorzoxazone-13C,15N,d2
Chlorzoxazone- ¹³C, ¹⁵N,d₂ is ¹³C-, ¹⁵N-, and deuterium-labeled Chlorzoxazone (HY-B1462) .

HY-10285S

Saxagliptin-15N,d2 hydrochloride
Saxagliptin-15N,d2 Hydrochloride (BMS-477118-15N,d2 Hydrochloride) is the ¹⁵N and deuterium labeled isotope of Saxagliptin (HY-10285). Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-W106835S1

N-(3-Hydroxybenzyl)adenosine-15N,d2
N-(3-Hydroxybenzyl)adenosine- ¹⁵N,d₂ is ¹⁵N and deuterium labeled N-(3-Hydroxybenzyl)adenosine .

HY-W016221S1

6-Hydroxy Chlorzoxazone-15N,d2
6-Hydroxy Chlorzoxazone- ¹⁵N,d₂ is the ¹⁵N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221) .

HY-N0717S9

L-Valine-15N,d8
L-Valine- ¹⁵N,d₈ is the deuterium and 15 N labeled L-Valine[1]. L-Valine (Valine) is a new nonlinear semiorganic material[2].

HY-N0666S9

L-Aspartic acid-15N,d3
L-Aspartic acid- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

HY-N0771S7

L-Isoleucine-15N,d10
L-Isoleucine- ¹⁵N,d₁₀ is the deuterium and ¹⁵N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

HY-N0326S9

L-Methionine-15N,d8
L-Methionine- ¹⁵N,d₈ is the deuterium and ¹⁵N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

HY-Y0252S7

L-Proline-15N,d7
L-Proline- ¹⁵N,d₇ is the deuterium and ¹⁵N labeled L-Proline[1]. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0473S11

L-Tyrosine-15N,d7
L-Tyrosine- ¹⁵N,d₇ is the deuterium and ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0658S4

L-Threonine-15N,d5
L-Threonine- ¹⁵N,d₅ is the deuterium and ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

HY-N0666S5

L-Aspartic acid-13C4,15N,d3
L-Aspartic acid- ¹³C₄, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

HY-17436S4

Clevidipine-15N,d10
Clevidipine- ¹⁵N,d₁₀ is ¹⁵N and deuterated labeled Clevidipine (HY-17436). Clevidipine is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H)=-40 mV ).

HY-17427S

Emtricitabine-15N,d2
Emtricitabine- ¹⁵N,d₂ is a ¹⁵N-labeled and deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-N0771S6

L-Cysteine-13C3,15N,d3
L-Cysteine- ¹³C₃, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

HY-N0771S5

L-Isoleucine-13C6,15N,d10
L-Isoleucine- ¹³C₆, ¹⁵N,d₁₀ is the deuterium, ¹³C-, and 15-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

HY-16973S

Fluralaner-13C2,15N,d3
Fluralaner- ¹³C₂, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.

HY-B0084S4

Dienogest-13C,15N,d4

Dienogest-13C,15N,d4 (STS 557-13C,15N,d4) is the ¹³C, ¹⁵N and deuterium labeled isotope of Dienogest (HY-B0084). Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE₂ synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia .

HY-N0650S9

L-Serine-15N,d3
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-Y0966S9

Glycine-15N,d2
Glycine- ¹⁵N,d₂ is the deuterium and ¹⁵N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

HY-N0717S2

L-Valine-13C5,15N,d8
L-Valine- ¹³C₅, ¹⁵N,d₈ is the deuterium, ¹³C-, and 15-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].

HY-N0717S3

L-Valine-13C5,15N,d2
L-Valine- ¹³C₅, ¹⁵N,d₂ is the deuterium, ¹³C-, and 15-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].

HY-N0658S2

L-Threonine-13C4,15N,d5
L-Threonine- ¹³C₄, ¹⁵N,d₅ is the deuterium, ¹³C-, and 15-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

HY-Y0252S6

L-Proline-13C5,15N,d7
L-Proline- ¹³C₅, ¹⁵N,d₇ is the deuterium, ¹³C and ¹⁵N labeled L-Proline[1]. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0229S14

L-Alanine-15N,d4
L-Alanine- ¹⁵N,d₄ is the deuterium and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-A0042S1

Rufinamide-15N,d2
Rufinamide- ¹⁵N,d₂ is the deuterium and ¹⁵N labeled Rufinamide[1]. Rufinamide is a new antiepileptic agent that differs structurally from other antiepileptic agents and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS)[2][3].

HY-N0650S12

L-Serine-d3,15n
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N labeled L-Serine[1]. L-Serine ((-)-Serine;(S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation[2].

HY-N0650S3

L-Serine-13C3,15N,d3
L-Serine- ¹³C₃, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0229S5

L-Alanine-13C3,15N,d4
L-Alanine- ¹³C₃, ¹⁵N,d₄ is the deuterium, ¹³C-, and 15-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-W002004S

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17,15N
4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl- ¹⁵N,d₇ is the deuterium and ¹⁵N labeled 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl[1].

HY-Y0966S11

Glycine-13C2,15N,d2
Glycine- ¹³C₂, ¹⁵N,d₂ is the deuterium, ¹³C and ¹⁵N labeled Glycine[1]. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[2].

HY-13613S2

Dutasteride-13C,15N,d
Dutasteride- ¹³C, ¹⁵N,d is ¹⁵N and deuterated labeled Dutasteride (HY-13613). Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT .

HY-14608S9

L-Glutamic acid-15N,d5
L-Glutamic acid- ¹⁵N,d₅ is the deuterium and ¹⁵N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

HY-10981S2

Lenvatinib-15N,d4
Lenvatinib- ¹⁵N,d₄ is ¹⁵N and deuterated labeled Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities .

HY-14608S4

L-Glutamic acid-13C5,15N,d5
L-Glutamic acid- ¹³C₅, ¹⁵N,d₅ is the deuterium, ¹³C-, and 15-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

HY-A0166S

Cilastatin-15N,d3
Cilastatin- ¹⁵N,d₃ is a ¹⁵N-labeled and deuterium labeled Cilastatin. Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin is an antibacterial adjunct[1][2][3].

HY-W015007S

Metyrosine-13C9,15N,d7
Metyrosine- ¹³C₉, ¹⁵N,d₇ is the deuterium, ¹³C-, and 15-labeled Metyrosine. Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity[1]. Metyrosine is a very effective agent for blood pressure control[2].

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HY-P82344

	MT ND1 Antibody (YA2089) MT-ND1; MTND1; NADH1; ND1; NADH-ubiquinone oxidoreductase chain 1; NADH dehydrogenase subunit 1	WB	Human, Mouse, Rat
	MT ND1 Antibody (YA2089) is a non-conjugated IgG antibody, targeting MT ND1, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). MT ND1 Antibody (YA2089) can be used for WB experiment in human, mouse, rat background.

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