Search Result
Results for "
Sesquiterpenoids
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N10321
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Others
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Others
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Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots .
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- HY-122375
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Others
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Others
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Palustrol is a natural sesquiterpenoid compound .
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- HY-N8736
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Others
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Others
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Eicosanyl (E)-caffeate is a sesquiterpenoid isolated from the root of Wikstroemia scytophylla .
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- HY-134572
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Others
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Others
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(2S,3S)-Pterosin C is a natural sesquiterpenoid compound .
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- HY-N3174
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Others
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Others
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(2R)-Norpterosin B is a sesquiterpenoid isolated from Pteris semipinnata .
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- HY-N1571
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Others
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Others
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Pterosin D is a sesquiterpenoid, that can be isolated from aerial plants of P. cretica .
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- HY-N10163
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(+)-1β,10β-Epoxydesacetoxymatricarin
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Others
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Others
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1β,10β-Epoxydesacetoxymatricarin is a sesquiterpenoids that can be isolated from Carthamus oxycantha .
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- HY-N11480
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Others
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Others
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(2E)-Leocarpinolide F (Compound 20), a germacrane-type sesquiterpenoid, can be isolated from Sigesbeckia orientalis .
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- HY-N7606
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Others
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Others
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(Rac)-β-Chamigrenic acid is a racemate of β-Chamigrenic acid. β-Chamigrenic acid is a sesquiterpenoid isolated from S.chinensis
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- HY-N12266
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Others
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Others
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12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .
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- HY-N12191
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HSV
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Others
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Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV) .
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- HY-N10218
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Others
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Inflammation/Immunology
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Sterpurol D is a compound of the sterpurane sesquiterpenoid. Sterpurol D significantly inhibits nitric oxide (NO) production .
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- HY-N10683
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Others
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Others
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1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum containing a benzoyl and a cinnamoyl group .
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- HY-N8103
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Amyloid-β
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Neurological Disease
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Heishuixiecaoline A is a germacrane-type sesquiterpenoid. Heishuixiecaoline A shows protective effect on the neurotoxicity of PC12 cells induced by Aβ25-35 .
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- HY-119735
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Others
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Cardiovascular Disease
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Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .
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- HY-N10014
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Fungal
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Infection
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Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC50 value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .
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- HY-N8934
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Others
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Cancer
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6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines .
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- HY-N8136
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Others
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Others
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Volvalerenic acid A is a germacrane-type sesquiterpenoid that can be found in the roots of Valeriana officinalis var. latifolia .
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- HY-N5081
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Others
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Cancer
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1αH,5αH-Guaia-6-ene-4β,10β-diol is a sesquiterpenoid derivative identified from Alisma orientale. 1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities .
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- HY-N3879
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Others
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Others
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Eudesm-4(14)-ene-3α,11-diol (compound 2) is a sesquiterpenoid. Eudesm-4(14)-ene-3α,11-diol can be isolated from Neocallitropsis Pancheri Florin .
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- HY-N8862
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Others
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Inflammation/Immunology
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Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC50 value of 24 μM .
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- HY-N3241
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Bacterial
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Infection
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Mucrolidin is an eudesmane-type sesquiterpenoid isolated from aerial parts of homalomena occulta. Mucrolidin exhibits weak antibacterial activities when it compares to Rifampicin (HY-B0272) .
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- HY-N10458
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NF-κB
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Inflammation/Immunology
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Asperbisabolane L, a sesquiterpenoid, exerts the anti-inflammatory activity by inhibiting the NF-κB-activated pathway. Asperbisabolane L inhibits the translocation of NF-κB from cytoplasm to the nucleus. Asperbisabolane L also inhibits NO production in LPS-activated BV-2 microglia cells .
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- HY-N10116A
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Others
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Cancer
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Calamenene is a major sesquiterpenoid, which could be isolated from Cupressus bakeri foliage. Calamenene affects the maturation and function of human monocyte-derived dendritic cells .
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- HY-N3340
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Fungal
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Infection
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Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .
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- HY-N9239
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Others
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Others
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Turmeronol A is a sesquiterpenoid compound.
Turmeronol A has anti-inflammatory activity. Turmeronol A prevents macrophage
activation and the production of inflammatory mediators by inhibiting the
activation of NFκB. Turmeronol A can be used to prevent chronic inflammatory
diseases .
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- HY-N8404
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Potassium Channel
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Inflammation/Immunology
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Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM .
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- HY-N9046
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NO Synthase
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Inflammation/Immunology
Cancer
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Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC50 of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC50 values of 27.52 μM and 29.51 μM, respectively .
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- HY-N10364
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Others
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Cancer
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6β,7β-Epoxyasteriscunolide A, a sesquiterpenoid, shows cytotoxicity against the HL-60 and MOLT-3 leukemia cell lines, with IC50s range 4.1-5.4 μM .
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- HY-N0104
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Curcumol
Maximum Cited Publications
7 Publications Verification
(-)-Curcumol
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Apoptosis
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Cancer
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Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .
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- HY-N10577
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TGF-beta/Smad
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Cancer
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Chlorfortunone A is a novel sesquiterpenoid dimers, can be isolated from the roots of Chloranthus fortunei. Chlorfortunone A inhibits transforming growth factor (TGF)-β activity .
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- HY-N0104R
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Apoptosis
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Cancer
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Curcumol (Standard) is the analytical standard of Curcumol. This product is intended for research and analytical applications. Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .
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- HY-N2885
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- HY-N10623
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Tyrosinase
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Cancer
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5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells .
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- HY-N8312
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Others
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Others
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Bakkenolide IIIa is a natural sesquiterpenoid compound .
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- HY-N0065
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- HY-N9626
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(R)-Cuparene
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Others
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Others
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Cuparene ((R)-Cuparene) is a sesquiterpenoid and can be isolated from Cupressaceae .
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- HY-N11547
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Others
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Others
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Leocarpinolide F is a natural sesquiterpenoid that can be isolated from Siegesbeckia orientalis .
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- HY-N3152
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Others
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Others
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O-Geranylconiferyl alcohol is a sesquiterpenoids? isolated from? the root of Ligularia duciformis .
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- HY-N8938
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Others
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Others
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Jasminoid A is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus japonicus .
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- HY-N2856
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Others
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Others
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Alpiniaterpene A is a Sesquiterpenoids product that can be isolated from the rhizomes of Alpinia officinarum. .
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- HY-N3537
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Others
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Others
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Canusesnol A is a Sesquiterpenoids product that can be isolated from the herbs of Datura arborea .
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- HY-N3538
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Others
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Others
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Carabrolactone A is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
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- HY-N3577
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Others
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Others
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Chlorantholide A is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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- HY-N3583
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Others
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Others
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Chlorouvedalin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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- HY-N9302
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Others
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Others
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Chromolaenide is a Sesquiterpenoids product that can be isolated from the herbs of Chromolaena glaberrima. .
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- HY-N9209
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Others
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Others
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Cinalbicol is a Sesquiterpenoids product that can be isolated from the roots of Cacalia roborowskii. .
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- HY-N3605
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Others
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Others
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Clovanediol diacetate is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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- HY-N3723
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Others
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Others
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Demethylsonchifolin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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- HY-N3726
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Others
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Others
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Dendocarbin A is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
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- HY-N1883
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Others
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Others
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Epoxyarteannuinic acid is a Sesquiterpenoids product that can be isolated from the herbs of Artemisia annua L. .
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- HY-N3840
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Others
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Others
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Epoxyparvinolide is a Sesquiterpenoids product that can be isolated from the herbs of Pogostemon parviflorus .
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- HY-N3910
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Others
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Others
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Fuegin is a Sesquiterpenoids product that can be isolated from the herb of Polygonum hydropiper .
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- HY-135444
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Others
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Others
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Heliangin is a Sesquiterpenoids product that can be isolated from the herbs of Helianthus tuberosus L. .
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- HY-N4040
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Others
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Others
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Homalomenol A is a Sesquiterpenoids product that can be isolated from the roots of Homalomena aromatica. .
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- HY-N3499
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Others
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Others
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Isocalamendiol is a Sesquiterpenoids product that can be isolated from the roots of Acorus calamus L. .
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- HY-N9230
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Others
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Others
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Isocuparenal is a Sesquiterpenoids product that can be isolated from the herbs of Lepidozia reptans .
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- HY-N3337
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Others
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Others
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Macrocarpal L is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus .
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- HY-N3046
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Others
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Others
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Piptocarphin A is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
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- HY-N3038
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Others
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Others
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Polygonal is a Sesquiterpenoids product that can be isolated from the roots of Polygonum hydropiper .
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- HY-N8657
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Others
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Others
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Pyrocurzerenone is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus sertusra .
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- HY-N1194A
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Others
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Others
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Sulfocostunolide A is a Sesquiterpenoids product that can be isolated from the root of Saussurea lappa .
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- HY-N1169
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Others
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Others
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Tectoroside is a Sesquiterpenoids product that can be isolated from the herbs of Crepis crocea. .
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- HY-N1139
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Others
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Others
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Torilolone is a Sesquiterpenoids product that can be isolated from the herbs of Cnidium monnieri. .
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- HY-133196
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Others
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Others
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Ustusolate A is a Sesquiterpenoids product that can be isolated from From Aspergillus ustus .
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- HY-N7336
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Others
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Others
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Wedelialactone A is a Sesquiterpenoids product that can be isolated from the herbs of Wedelia trilobata .
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- HY-N9116
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Others
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Others
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Unedone is a Sesquiterpenoids product that can be isolated from the herbs of Lysimachia clethroides .
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- HY-N9053
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Others
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Others
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Wedeliatrilolactone A is a Sesquiterpenoids product that can be isolated from the herbs of Wedelia trilobata .
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- HY-126484
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Others
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Others
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Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .
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- HY-121174
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Catharticin
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Others
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Others
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Alaternin (Catharticin) is a Sesquiterpenoids product that can be isolated from the leaves of Platycladus orientalis .
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- HY-N9287
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Others
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Others
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Breyniaionoside A is a Sesquiterpenoids product that can be isolated from the leaves of Breynia officinalis HEMSL. .
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- HY-N9221
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Others
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Others
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Bakkenolide III is a Sesquiterpenoids product that can be isolated from the roots of Petasites formosanus. .
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- HY-N3539
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Others
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Others
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Carabrolactone B is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
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- HY-N3578
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Others
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Others
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Chlorantholide B is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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- HY-N3580
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Others
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Others
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Chlorantholide D is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus spicatus .
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- HY-N3581
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Others
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Others
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Chlorantholide E is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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- HY-126205
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Others
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Others
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Deacetyleupaserrin is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium semiserratum DC. .
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- HY-N3582
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Others
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Others
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Enhydrin chlorohydrin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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- HY-N3830
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Others
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Others
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Epiguajadial B is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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- HY-N3982
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Others
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Others
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Guajadial B is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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- HY-133219A
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Others
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Others
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Guajadial D is a Sesquiterpenoids product that can be isolated from the leaves of Psidium guajava. .
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- HY-N7313
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Others
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Others
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Macrocarpal O is a Sesquiterpenoids product that can be isolated from the leaves of Eucalyptus globulus. .
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- HY-N1315
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Others
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Others
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Sarcandrolide D is a Sesquiterpenoids product that can be isolated from the herbs of Sarcandra glabra. .
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- HY-N9074
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Others
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Others
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Shizukanolide H is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus spicatus .
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- HY-N1194
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Others
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Others
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Sulfocostunolide B is a Sesquiterpenoids product that can be isolated from the roots of Saussurea lappa .
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- HY-N8778
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Others
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Others
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Intermedin B is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia. .
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- HY-N8843
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Others
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Others
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Mollisorin A is a Sesquiterpenoids product that can be isolated from the aerial parts of Ophryosporus lorentzii. .
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- HY-N3576
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Chloramultilide D
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Others
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Others
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Henriol B (Chloramultilide D) is a dimeric sesquiterpenoid that can be isolated from C. spicatus .
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- HY-119528
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Bacterial
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Infection
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Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea .
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- HY-N1144
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Normacusine B; 10-Deoxysarpagine; Vellosiminol
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Others
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Others
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Tombozine (Normacusine B) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
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- HY-N3833
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Others
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Others
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Epipterosin L is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
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- HY-N1587
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Others
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Others
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15-Dihydroepioxylubimin is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
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- HY-N9486
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Others
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Others
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2-Hydroxyeupatolide is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium lindleyanum .
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- HY-N8795
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Others
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Others
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2-Hydroxyplatyphyllide is a Sesquiterpenoids product that can be isolated from the roots of Ligularia songarica. .
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- HY-N9270
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Others
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Others
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3-Epichromolaenide is a Sesquiterpenoids product that can be isolated from the herbs of Chromolaena glaberrima .
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- HY-N1840
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Others
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Others
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3-Hydroxycatalponol is a Sesquiterpenoids product that can be isolated from the roots of Ekmanianthe longiflora .
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- HY-N2804
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Others
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Others
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9-Oxoageraphorone is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum .
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- HY-N2904
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Others
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Others
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Ascleposide E is a Sesquiterpenoids product that can be isolated from the roots of Aucklandia lappa Decne .
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- HY-N8953
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Others
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Others
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Bisacurone C is a Sesquiterpenoids product that can be isolated from the root tubers of Curcuma longa. .
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- HY-N3645
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Others
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Others
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Cucumegastigmane I is a Sesquiterpenoids product that can be isolated from the fruits of Trichosanthes kirilowii Maxim .
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- HY-N7337
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Others
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Others
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Dibritannilactone B is a Sesquiterpenoids product that can be isolated from the aerial parts of Inula britannica. .
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- HY-N3336
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Others
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Others
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Macrocarpal N is a Sesquiterpenoids product that can be isolated from the twigs of Eucalyptus globules Labill .
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- HY-N3273
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Others
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Others
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Methyl isodrimeninol is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum flaccidum Meissn. .
|
-
- HY-N1174
-
|
Taxagifin
|
Others
|
Others
|
|
Taxagifine (Taxagifin) is a Sesquiterpenoids product that can be isolated from the leaves of Breynia officinalis HEMSL. .
|
-
- HY-N1095
-
|
Verbenacin
|
Others
|
Others
|
|
Verbenacine (Verbenacin) is a Sesquiterpenoids product that can be isolated from the aerial parts of Ophryosporus lorentzii. .
|
-
- HY-N2846
-
|
|
Others
|
Others
|
|
α-Epoxydihydroartemisinic acid is a Sesquiterpenoids product that can be isolated from the herbs of Artemisia annua L. .
|
-
- HY-N9122
-
|
|
Others
|
Others
|
|
4'-Hydroxypiptocarphin A is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
|
-
- HY-N8958
-
|
|
Others
|
Others
|
|
Deacetylorientalide (compound 19) is a germacrane-type sesquiterpenoid compound that can be found in from Sigesbeckia orientalis .
|
-
- HY-N9103
-
|
|
Others
|
Others
|
|
Norpterosin B glucoside is a Sesquiterpenoids product that can be isolated from the aerial parts of Pteris semipinnata. .
|
-
- HY-N1007
-
|
|
Others
|
Others
|
|
10-O-Acetylisocalamendiol is a Sesquiterpenoids product that can be isolated from the roots of Acorus calamus L. .
|
-
- HY-N1015
-
|
|
Others
|
Others
|
|
11,13-Dihydroivalin is a Sesquiterpenoids product that can be isolated from the herbs of Blumea balsamifera .
|
-
- HY-N1042
-
|
|
Others
|
Others
|
|
13-O-Acetylcorianin is a Sesquiterpenoids product that can be isolated from the herbs of Coriaria nepalensis .
|
-
- HY-N1617
-
|
|
Others
|
Others
|
|
1beta-Hydroxytorilin is a Sesquiterpenoids product that can be isolated from the fruits of Torilis japonica. .
|
-
- HY-N9214
-
|
|
Others
|
Others
|
|
1-Oxobakkenolide S is a Sesquiterpenoids product that can be isolated from the roots of Petasites formosanus .
|
-
- HY-N1862
-
|
|
Others
|
Others
|
|
3-O-Methyltirotundin is a Sesquiterpenoids product that can be isolated from the herbs of Tithonia diversifolia .
|
-
- HY-N2771
-
|
|
Others
|
Others
|
|
8-Epicrepiside E is a Sesquiterpenoids product that can be isolated from the roots of Saussurea costus .
|
-
- HY-N2781
-
|
|
Others
|
Others
|
|
8-O-Acetyltorilolone is a Sesquiterpenoids product that can be isolated from the herbs of Cnidium monnieri. .
|
-
- HY-N3589
-
|
3-Deoxyryanodol
|
Others
|
Others
|
|
Cinnzeylanol (3-Deoxyryanodol) is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N3338
-
|
(-)-Macrocarpal K; 9'-epi-Macrocarpal H
|
Others
|
Others
|
|
Macrocarpal K ((-)-Macrocarpal K) is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N1573
-
|
|
Others
|
Others
|
|
Pterosin Z is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N8403
-
|
|
Others
|
Others
|
|
Vibralactone B is a Sesquiterpenoids product that can be isolated from From the cultures of the Basidiomycete Boreostereum vibrans. .
|
-
- HY-N9198
-
|
|
Others
|
Others
|
|
13-O-Ethylpiptocarphol is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
|
-
- HY-N8689
-
|
|
Others
|
Others
|
|
4-Epi-curcumenol is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma zedoaria .
|
-
- HY-N9268
-
|
|
Others
|
Others
|
|
8β-Tigloyloxyreynosin is a Sesquiterpenoids product that can be isolated from the roots of Dolomiaea souliei .
|
-
- HY-N8959
-
|
|
Others
|
Others
|
|
9-O-Ethyldeacetylorientalide is a Sesquiterpenoids product that can be isolated from the herbs of Euphorbia pekinensis .
|
-
- HY-N12024
-
|
(-)-Linderanine C
|
Others
|
Others
|
|
Linderanine C ((-)-Linderanine C) (compound 6) is a sesquiterpenoid compound that can be isolated from the roots of Wuyao .
|
-
- HY-N1892
-
|
O-Demethyleucomin
|
Others
|
Others
|
|
4'-Demethyleucomin (O-Demethyleucomin) is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
|
-
- HY-N1895
-
|
|
Others
|
Others
|
|
4-epi-Isoinuviscolide is a Sesquiterpenoids product that can be isolated from the herbs of Inula lineariifolia Turcz. .
|
-
- HY-N2667
-
|
|
Others
|
Others
|
|
5β-Hydroxycostic acid is a Sesquiterpenoids product that can be isolated from the roots of Aucklandia lappa Decne .
|
-
- HY-N2718
-
|
|
Others
|
Others
|
|
6-O-Acetylcoriatin is a Sesquiterpenoids product that can be isolated from the herbs of Coriaria nepalensis Wall. .
|
-
- HY-N2793
-
|
|
Others
|
Others
|
|
9-Epiblumenol B is a Sesquiterpenoids product that can be isolated from the herbs of Rosa multiflora Thunb. .
|
-
- HY-N3644
-
|
|
Others
|
Others
|
|
Cryptomeridiol 11-rhamnoside is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus Labill. .
|
-
- HY-N3135
-
|
|
Others
|
Others
|
|
Onitin 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the herbs of Onychium japonicum .
|
-
- HY-N3166
-
|
|
Others
|
Others
|
|
Onitisin 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the herbs of Onychium japonicum .
|
-
- HY-N9201
-
|
|
Others
|
Others
|
|
8beta-Methoxyatractylenolide I is a Sesquiterpenoids product that can be isolated from the rhizomes of Atractylodes macrocephala. .
|
-
- HY-N9260
-
|
|
Others
|
Inflammation/Immunology
|
|
4E-Deacetylchromolaenide 4'-O-acetate (Compound 11) is a sesquiterpenoid that can be isolated fromEupatorium chinense L. .
|
-
- HY-N1001
-
|
|
Others
|
Others
|
|
1,9-Caryolanediol 9-acetate is a Sesquiterpenoids product that can be isolated from the herbs of Sindora sumatrana. .
|
-
- HY-N2766
-
|
|
Others
|
Others
|
|
8alpha-Hydroxy-alpha-gurjunene is a Sesquiterpenoids product that can be isolated from the herbs of Sarcandra glabra .
|
-
- HY-N7323
-
|
|
Others
|
Others
|
|
Artemyriantholide D is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia myriantha Wall.ex Bess. .
|
-
- HY-N9114
-
|
1,5,6-Trihydroxyxanthone
|
Others
|
Others
|
|
Mesuaxanthone B (1,5,6-Trihydroxyxanthone) is a Sesquiterpenoids product that can be isolated from the fruits of Torilis japonica. .
|
-
- HY-N1627
-
|
|
Others
|
Others
|
|
2-Prenyl-1-naphthol is a Sesquiterpenoids product that can be isolated from the herbs of Catalpa ovata .
|
-
- HY-N1615
-
|
|
Others
|
Others
|
|
1beta-Hydroxy-beta-eudesmol is a Sesquiterpenoids product that can be isolated from the herbs of Cymbopogon proximus STAPF. .
|
-
- HY-N1889
-
|
|
Others
|
Others
|
|
4-Cadinen-7-ol is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum .
|
-
- HY-N2783
-
|
|
Others
|
Others
|
|
8'-Oxo-6-hydroxydihydrophaseic acid is a Sesquiterpenoids product that can be isolated from the roots of Illicium dunnianum. .
|
-
- HY-N3829
-
|
|
Others
|
Others
|
|
epi-Eudesmol is a Sesquiterpenoids product that can be isolated from the leaves of Laggera alata var. montana C. D. Adams. .
|
-
- HY-N3834
-
|
|
Others
|
Others
|
|
Epipterosin L 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N7353
-
|
|
Others
|
Others
|
|
Stachartin C is a Sesquiterpenoids product that can be isolated from the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. .
|
-
- HY-N6662
-
|
|
Endogenous Metabolite
|
Others
|
|
(+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
|
-
- HY-N9180
-
|
|
Others
|
Others
|
|
8α-Methacryloyloxy-13-ethoxyvernojalcanolide is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia esculenta .
|
-
- HY-N3590
-
|
|
Others
|
Others
|
|
cis-3,4-Dihydroxy-β-ionone is a Sesquiterpenoids product that can be isolated from the herbs of Gynura nepalensis. .
|
-
- HY-N1572
-
|
|
Others
|
Others
|
|
Pterosin D 3-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N9145
-
|
|
Others
|
Others
|
|
1beta,10beta-Epoxydehydroleucodin is a Sesquiterpenoids product that can be isolated from the roots of Scorzonera latifolia .
|
-
- HY-N9079
-
|
|
Others
|
Others
|
|
8alpha-(2-Methylacryloyloxy)hirsutinolide is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia cinerea. .
|
-
- HY-N9094
-
|
|
Others
|
Others
|
|
8α-Acetoxyarglabin is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia Myriantha Wall.Ex Bess. .
|
-
- HY-N9169
-
|
|
Others
|
Others
|
|
8β-(4-Hydroxytigloyloxy)ovatifolin is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium glehni .
|
-
- HY-N1869
-
|
|
Others
|
Others
|
|
4(15),11-Oppositadien-1-ol is a Sesquiterpenoids product that can be isolated from the roots of Homalomena aromatica. .
|
-
- HY-N0999
-
|
|
Others
|
Others
|
|
1,7-Diepi-8,15-cedranediol is a Sesquiterpenoids product that can be isolated from the leaves of Platycladus orientalis .
|
-
- HY-N9162
-
|
|
Others
|
Others
|
|
2α-Hydroxyeupatolide 8-O-angelate is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
|
-
- HY-N2691
-
|
|
Others
|
Others
|
|
6,8-Cyclo-1,4-eudesmanediol is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus robusta Smith .
|
-
- HY-N3304
-
|
|
Others
|
Others
|
|
7-Megastigmene-3,5,6,9-tetraol is a Sesquiterpenoids product that can be isolated from the herbs of Pandanus amaryllifolius .
|
-
- HY-N8940
-
|
|
Others
|
Others
|
|
1-O-Acetyl-6-O-isobutyrylbritannilactone is a Sesquiterpenoids product that can be isolated from the flower heads of Inula britannica. .
|
-
- HY-N8951
-
|
|
Others
|
Others
|
|
3,4-Dihydroxybisabola-1,10-diene is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb .
|
-
- HY-N1556
-
|
|
Estrogen Receptor/ERR
|
Metabolic Disease
Cancer
|
|
Psidial A is an epimer of sesquiterpenoid-diphenylmethane meroterpenoid. Psidial A may act as a selective estrogen receptors modulator. Psidial A also has potential for anticancer research .
|
-
- HY-N1806
-
|
|
Others
|
Others
|
|
3-Acetoxy-4-cadinen-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum. .
|
-
- HY-N3783
-
|
|
Others
|
Others
|
|
Drim-7-ene-11,12-diol acetonide is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
|
-
- HY-N2767
-
|
|
Others
|
Others
|
|
Naphtho[1,2-b]furan, 2-propenoic acid deriv. is a Sesquiterpenoids product that can be isolated from the herbs of Elephantopus scaber .
|
-
![Naphtho[1,2-b]furan, 2-propenoic acid deriv.](//file.medchemexpress.eu/product_pic/hy-n2767.gif)
- HY-N12335
-
|
|
Others
|
Others
|
|
Desacetylxanthanol (Compound 4) is a sesquiterpenoid derived from Xanthium strumarium. Desacetylxanthanol has anti-tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) activity .
|
-
- HY-159514
-
|
|
NO Synthase
COX
|
Inflammation/Immunology
|
|
Graveolide (Compound 5) is a sesquiterpenoid compound that can be isolated from C. abrotanoides. Graveolide possesses anti-inflammatory activity and can be utilized in the research of atopic dermatitis .
|
-
- HY-N9306
-
|
|
Others
|
Others
|
|
11-Hydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri. .
|
-
- HY-N2803
-
|
|
Others
|
Others
|
|
9-Oxo-2,7-bisaboladien-15-oic acid is a Sesquiterpenoids product that can be isolated from the barks of Pseudolarix kaempferi .
|
-
- HY-N3804
-
|
|
Others
|
Others
|
|
enantio-7(11)-Eudesmen-4-ol is a Sesquiterpenoids product that can be isolated from the herbs of Laggera pterodonta (DC.) Benth. .
|
-
- HY-N8756
-
|
|
Others
|
Others
|
|
3-Hydroxybisabola-1,10-dien-9-one is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-112006
-
|
(+)-alpha-Curcumene
|
Others
|
Others
|
|
(S)-ar-Curcumene ((+)-alpha-Curcumene) is a natural compound. (S)-ar-Curcumene is a constituent of the essential oil that can isolated from the rhizomes of Curcuma aromatica and is an odour component of distantly related corals .
|
-
- HY-N12136
-
|
|
Others
|
Others
|
|
1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) is a sesquiterpenoid obtained from star anise (Illicium merrillianum) isolated from the peel .
|
-
- HY-N11989
-
|
|
Others
|
Cancer
|
|
Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC50 of 38 μg/mL .
|
-
- HY-N8776
-
|
|
Others
|
Others
|
|
11-Hydroxybisabola-1,3,5-trien-9-one is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N1805
-
|
|
Others
|
Others
|
|
3-Acetoxy-4,7(11)-cadinadien-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum .
|
-
- HY-N1759
-
|
|
Others
|
Others
|
|
3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N2694
-
|
|
Others
|
Others
|
|
6,9,10-Trihydroxy-7-megastigmen-3-one is a Sesquiterpenoids product that can be isolated from the roots of Trigonostemon chinensis Merr. .
|
-
- HY-N9137
-
|
|
Others
|
Others
|
|
2α-Hydroxy-8β-(2-methylbutyryloxy)costunolide is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia myriantha .
|
-
- HY-N0974
-
|
|
Others
|
Others
|
|
1,10:4,5-Diepoxy-7(11)-germacren-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Isodon adenantha .
|
-
- HY-N9282
-
|
|
Others
|
Others
|
|
8alpha-(2-Methylacryloyloxy)-1-O-methylhirsutinolide 13-O-acetate is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia cinerea. .
|
-
- HY-N8946
-
|
|
Others
|
Others
|
|
1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone is a Sesquiterpenoids product that can be isolated from the flower heads of Inula britannica. .
|
-
- HY-N8667
-
|
|
Others
|
Others
|
|
7-Epi-5-eudesmene-1beta,11-diol is a Sesquiterpenoids product that can be isolated from the herbs of Physalis alkekengi .
|
-
- HY-N1810
-
|
3α,6β-Ditigloyloxytropan-7β-ol
|
Others
|
Others
|
|
Ditigloylteloidine (3α,6β-Ditigloyloxytropan-7β-ol) is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
|
-
- HY-N1807
-
|
3-Acetoxy-5-methoxystilbene
|
Others
|
Others
|
|
(E)-3-Acetoxy-5-methoxystilbene (3-Acetoxy-5-methoxystilbene) is a Sesquiterpenoids product that can be isolated from the roots of Ligularia songarica. .
|
-
- HY-N1024
-
|
|
Others
|
Others
|
|
11R,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N1024A
-
|
|
Others
|
Others
|
|
11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N9091
-
|
|
Others
|
Others
|
|
9α,11-Dihydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri .
|
-
- HY-N1896
-
|
|
Others
|
Others
|
|
4-Hydroxy-1,10-secocadin-5-ene-1,10-dione is a Sesquiterpenoids product that can be isolated from the leaves of Casearia sylvestris. .
|
-
- HY-N1897
-
|
|
Others
|
Others
|
|
4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a Sesquiterpenoids product that can be isolated from the roots of Euphorbia fischeriana. .
|
-
- HY-N9278
-
|
|
Others
|
Others
|
|
8beta-(2-Hydroxy-2-methyl-3-oxobutyryloxy)glucozaluzanin C is a Sesquiterpenoids product that can be isolated from the herbs of Crepis crocea. .
|
-
- HY-W854294
-
|
|
Others
|
Others
|
|
3,4-Seco-3-oxobisabol-10-ene-4,1-olide is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N9078
-
|
|
Others
|
Others
|
|
9alpha,11,12-Trihydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri .
|
-
- HY-119635
-
|
|
Others
|
Cancer
|
|
Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes .
|
-
- HY-N6662R
-
|
|
Endogenous Metabolite
|
Others
|
|
(+)-Longifolene (Standard) is the analytical standard of (+)-Longifolene. This product is intended for research and analytical applications. (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
|
-
- HY-N2850
-
|
5α-Stigmasta-7,22-dien-3β-ol, acetate; Spinasteryl acetate
|
Others
|
Others
|
|
α-Spinasterol acetate (5α-Stigmasta-7,22-dien-3β-ol, acetate) is a Sesquiterpenoids product that can be isolated from the roots of Trigonostemon chinensis Merr. .
|
-
- HY-N1837
-
|
|
Others
|
Others
|
|
3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide is a Sesquiterpenoids product that can be isolated from the roots of Xanthium sibiricum .
|
-
- HY-N1885
-
|
|
Others
|
Others
|
|
4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
|
-
- HY-N9040
-
|
|
Others
|
Others
|
|
6β-Angeloyloxy-1β,10β-epoxy-9-oxo-furaneremophilane is a Sesquiterpenoids product that can be isolated from the herbs of Ligularia songarica. .
|
-
- HY-W006454
-
|
1,5,6-Trihydropyridin-2-one
|
Others
|
Others
|
|
5,6-Dihydropyridin-2(1H)-one (1,5,6-Trihydropyridin-2-one) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N9175
-
|
|
Others
|
Others
|
|
4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
|
-
- HY-N10913
-
-
- HY-N8881
-
|
Jacaranone ethyl ester
|
Others
|
Others
|
|
Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate (Jacaranone ethyl ester) is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N8830
-
|
|
Others
|
Others
|
|
Selina-4(14),7(11)-dien-8-one is a sesquiterpene that can be isolated from Atractylodes Macrocephala Rhizoma .
|
-
- HY-N9187
-
|
|
Others
|
Others
|
|
1α,4β,10β-Trihydroxyguaia-2,11(13)-dien-12,6α-olide is a Sesquiterpenoids product that can be isolated from the rhizomes of Alisma orientale .
|
-
- HY-126637
-
|
|
Bacterial
Fungal
|
Infection
|
|
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
|
-
- HY-N2805
-
|
|
Bacterial
|
Infection
|
|
9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic .
|
-
- HY-N9018
-
|
|
Others
|
Others
|
|
4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma longa .
|
-
- HY-114604
-
|
|
Others
|
Others
|
|
Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
|
-
- HY-N12535
-
|
|
Others
|
Cancer
|
|
Tagitinin C is a sesquiterpenoid compound isolated from the Tithonia diversifolia. Tagitinin C has anticancer activity and can inhibit the proliferation of human glioblastoma U373 cells with an IC50 of 6.1 μg/mL. Tagitinin C can induce U373 cell death and be used in glioblastoma research .
|
-
- HY-N8936
-
|
|
Others
|
Inflammation/Immunology
|
|
Narchinol B (Compound 4) is a sesquiter penoid
compound. Narchinol B has anti-inflammatory effects. Narchinol B works by
inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2),
inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins,
as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor
necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced
overproduction of NO in BV2 cells (IC50=2.43 μM)
.
|
-
- HY-N2790
-
|
9,13α-Epidioxy-8(14)-abieten-18-oic acid
|
Others
|
Others
|
|
9α,13α-Epidioxyabiet-8(14)-en-18-oic acid (9,13α-Epidioxy-8(14)-abieten-18-oic acid) is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
|
-
- HY-103524
-
|
(-)-Valerenic Acid
|
GABA Receptor
5-HT Receptor
|
Neurological Disease
|
|
Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties .
|
-
- HY-N2095
-
|
Atractylon
|
Influenza Virus
|
Infection
Inflammation/Immunology
|
|
Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions .
|
-
- HY-N8413
-
|
|
Toll-like Receptor (TLR)
Reactive Oxygen Species
NF-κB
|
Inflammation/Immunology
|
|
Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α .
|
-
- HY-N10750
-
|
|
Others
|
Others
|
|
1α, 2α-Diacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (compound 7) is an eudesmane-type sesquiterpenoid that can be founfd in the the root bark of Pseudolarix kaempferi .
|
-
- HY-N1614
-
|
|
Others
|
Others
|
|
1 α-hydroxytorilin (compound 3) is a sesquiterpenoid. 1 α-hydroxytorilin can be isolated from Torilis japonica. 1α-hydroxytorilin has cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells with ED50 values of 20.52, 18.24, 17.48, 42.54 μg/mL, respectively .
|
-
- HY-N0202
-
|
Asterolide
|
ERK
Apoptosis
p38 MAPK
Akt
Src
STAT
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
|
-
- HY-103524R
-
|
(-)-Valerenic Acid (Standard)
|
5-HT Receptor
GABA Receptor
|
Neurological Disease
|
|
Valerenic acid (Standard) is the analytical standard of Valerenic acid. This product is intended for research and analytical applications. Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties .
|
-
- HY-121239
-
|
|
NF-κB
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni .
|
-
- HY-N0202R
-
|
|
ERK
Apoptosis
p38 MAPK
Src
Akt
STAT
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide II (Standard) is the analytical standard of Atractylenolide II. This product is intended for research and analytical applications. Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
|
-
- HY-N1870
-
|
|
Bacterial
|
Others
|
|
1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory .
|
-
- HY-N3980
-
|
Champacol; Guaiac alcohol
|
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
|
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N3840
-
-
- HY-N3910
-
-
- HY-135444
-
-
- HY-N4040
-
-
- HY-N3499
-
-
- HY-N9230
-
-
- HY-N3337
-
-
- HY-N3046
-
-
- HY-N3038
-
-
- HY-N8657
-
-
- HY-N1194A
-
-
- HY-N1169
-
-
- HY-N1139
-
-
- HY-133196
-
-
- HY-N7336
-
-
- HY-N9116
-
-
- HY-N9053
-
-
- HY-126484
-
-
- HY-121174
-
-
- HY-N9287
-
-
- HY-N9221
-
-
- HY-N3539
-
-
- HY-N3578
-
-
- HY-N3580
-
-
- HY-N3581
-
-
- HY-126205
-
-
- HY-N3582
-
-
- HY-N3830
-
-
- HY-N3982
-
-
- HY-133219A
-
-
- HY-N7313
-
-
- HY-N1315
-
-
- HY-N9074
-
-
- HY-N1194
-
-
- HY-N8778
-
-
- HY-N8843
-
-
- HY-N3576
-
-
- HY-119528
-
-
- HY-N1144
-
-
- HY-N3833
-
-
- HY-N1587
-
-
- HY-N9486
-
-
- HY-N8795
-
-
- HY-N9270
-
-
- HY-N1840
-
-
- HY-N2804
-
-
- HY-N2904
-
-
- HY-N8953
-
-
- HY-N3645
-
-
- HY-N7337
-
-
- HY-N3336
-
-
- HY-N3273
-
-
- HY-N1174
-
-
- HY-N1095
-
-
- HY-N2846
-
-
- HY-N9122
-
-
- HY-N8958
-
-
- HY-N9103
-
-
- HY-N1007
-
-
- HY-N1015
-
-
- HY-N1042
-
-
- HY-N1617
-
-
- HY-N9214
-
-
- HY-N1862
-
-
- HY-N2771
-
-
- HY-N2781
-
-
- HY-N3589
-
-
- HY-N3338
-
-
- HY-N1573
-
-
- HY-N8403
-
-
- HY-N9198
-
-
- HY-N8689
-
-
- HY-N9268
-
-
- HY-N8959
-
-
- HY-N12024
-
-
- HY-N1892
-
-
- HY-N1895
-
-
- HY-N2667
-
-
- HY-N2718
-
-
- HY-N2793
-
-
- HY-N3644
-
-
- HY-N3135
-
-
- HY-N3166
-
-
- HY-N9201
-
-
- HY-N9260
-
-
- HY-N1001
-
-
- HY-N2766
-
-
- HY-N7323
-
-
- HY-N9114
-
-
- HY-N1627
-
-
- HY-N1615
-
-
- HY-N1889
-
-
- HY-N2783
-
-
- HY-N3829
-
-
- HY-N3834
-
-
- HY-N7353
-
-
- HY-N6662
-
-
- HY-N9180
-
-
- HY-N3590
-
-
- HY-N1572
-
-
- HY-N9145
-
-
- HY-N9079
-
-
- HY-N9094
-
-
- HY-N9169
-
-
- HY-N1869
-
-
- HY-N0999
-
-
- HY-N9162
-
-
- HY-N2691
-
-
- HY-N3304
-
-
- HY-N8940
-
-
- HY-N8951
-
-
- HY-N1556
-
-
- HY-N1806
-
-
- HY-N3783
-
-
- HY-N2767
-
-
- HY-N12335
-
-
- HY-159514
-
-
- HY-N9306
-
-
- HY-N2803
-
-
- HY-N3804
-
-
- HY-N8756
-
-
- HY-N12136
-
-
- HY-N11989
-
-
- HY-N8776
-
-
- HY-N1805
-
-
- HY-N1759
-
-
- HY-N2694
-
-
- HY-N9137
-
-
- HY-N0974
-
-
- HY-N9282
-
-
- HY-N8946
-
-
- HY-N8667
-
-
- HY-N1810
-
-
- HY-N1807
-
-
- HY-N1024
-
-
- HY-N1024A
-
-
- HY-N9091
-
-
- HY-N1896
-
-
- HY-N1897
-
-
- HY-N9278
-
-
- HY-W854294
-
-
- HY-N9078
-
-
- HY-119635
-
-
- HY-N6662R
-
-
- HY-N2850
-
-
- HY-N1837
-
-
- HY-N1885
-
-
- HY-N9040
-
-
- HY-W006454
-
-
- HY-N9175
-
-
- HY-N10913
-
-
- HY-N8881
-
-
- HY-N8830
-
-
- HY-N9187
-
-
- HY-126637
-
|
|
Structural Classification
Microorganisms
Antibiotics
Source classification
Other Antibiotics
|
Bacterial
Fungal
|
|
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
|
-
- HY-N2805
-
-
- HY-N9018
-
-
- HY-114604
-
|
|
Structural Classification
Natural Products
Microorganisms
Source classification
|
Others
|
|
Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
|
-
- HY-N12535
-
-
- HY-N8936
-
-
- HY-N2790
-
-
- HY-N2095
-
-
- HY-N8413
-
-
- HY-N10750
-
-
- HY-N1614
-
-
- HY-N0202
-
-
- HY-121239
-
|
|
Structural Classification
Natural Products
Animals
Source classification
|
NF-κB
|
|
Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni .
|
-
- HY-N0202R
-
|
|
Structural Classification
Terpenoids
Sesquiterpenes
Source classification
Astragalus caprinus L.
Plants
Compositae
|
ERK
Apoptosis
p38 MAPK
Src
Akt
STAT
|
|
Atractylenolide II (Standard) is the analytical standard of Atractylenolide II. This product is intended for research and analytical applications. Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
|
-
- HY-N1870
-
-
- HY-N3980
-
|
Champacol; Guaiac alcohol
|
Infection
Structural Classification
Natural Products
Classification of Application Fields
Source classification
Distemonanthus benthamianus Baill.
Plants
Compositae
Disease Research Fields
|
Autophagy
RAD51
|
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
|
Structural Classification
Natural Products
Source classification
Distemonanthus benthamianus Baill.
Plants
Compositae
|
Autophagy
RAD51
|
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
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![Naphtho[1,2-b]furan, 2-propenoic acid deriv.](http://file.medchemexpress.eu/product_pic/hy-n2767.gif)
