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Results for "

adenosine A2A receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (79) Amyloid-β (1) Apoptosis (13) Autophagy (13) Calcium Channel (1) Dopamine Receptor (1) Drug Metabolite (2) Endogenous Metabolite (19) HDAC (1) Isotope-Labeled Compounds (6) Monoamine Oxidase (2) Nucleoside Antimetabolite/Analog (13) PI3K (1)
By Research Areas:	Cancer (37) Cardiovascular Disease (12) Infection (1) Inflammation/Immunology (24) Metabolic Disease (14) Neurological Disease (40)

101

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Adenosine Kinase Adenosine Receptor Adenosine Deaminase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103162

ANR94	Adenosine Receptor	Neurological Disease
ANR94 is a potent and selective adenosine A_2A receptor (AA_2AR) antagonist with an K_i of 46 nM for hAA_2AR. ANR94 has the potential for the research of Parkinson's disease .

HY-103164

(E)-8-(3-Chlorostyryl)caffeine	Adenosine Receptor Monoamine Oxidase	Neurological Disease
(E)-8-(3-Chlorostyryl)caffeine is a selective **adenosine A_2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a K_i** value of 70 nM by a pathway that is independent of its actions on the A_2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research .

HY-10995

Tozadenant 2 Publications Verification SYN115	Adenosine Receptor	Neurological Disease
Tozadenant is an **adenosine A_2A** receptor antagonist, with K_i of 11.5 nM on human A_2A and 6 nM on rhesus A_2A.

HY-105068

Apadenoson BMS 068645; DWH 146e	Adenosine Receptor	Cardiovascular Disease
Apadenoson is an adenosine analog with selective agonist activity for the adenosine *A_2a* receptor and induces coronary vasodilatation .

HY-120941

LASSBio-1359	Adenosine Receptor	Cardiovascular Disease Inflammation/Immunology
LASSBio-1359 is an **adenosine A2A receptor** agonist with vasodilatory and anti-inflammatory activities .

HY-117184

MSX-2	Adenosine Receptor	Neurological Disease
MSX-2 is A2A **adenosine receptor antagonist, with K_i** of 5 nM in human that plays an important role in Parkinson's disease .

HY-147908

Adenosine receptor inhibitor 2	Adenosine Receptor	Inflammation/Immunology
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor. Adenosine receptor inhibitor 2 shows dual affinity toward A₁/A_2A ARs with higher affinity for the A₁- than the A_2AAR. Adenosine receptor inhibitor 2 has K_i values of 52.2 nM for the A₁AR and 167 nM for the A_2AAR .

HY-U00180

KF21213	Adenosine Receptor	Neurological Disease
KF21213 is a highly selective ligand for mapping CNS adenosine *A_2A* receptors. KF21213 shows a high affinity for the adenosine *A_2A* receptors (K_i=3.0 nM).

HY-U00341

ST4206	Adenosine Receptor	Neurological Disease
ST4206 is a potent and orally active **adenosine A2A receptor antagonist, with K_i*s of 12 nM and 197 nM for adenosine* A2A receptor and adenosine A1 receptor, respectively. ST4206 has the potential for Parkinson׳s disease research .

HY-112840

ST3932	Adenosine Receptor	Neurological Disease
ST3932 is a metabolite of ST1535, acts as an antagonist of **adenosine A_2A receptor, with K_i*s of 8 nM and 33 nM for A_2A* and A₁ receptors, respectively.

HY-111088

LUF5981	Adenosine Receptor	Others
LUF5981 is a relatively potent **adenosine A2A receptor (A2A)** antagonist with pIC₅₀ value of 6.7 .

HY-102024

A2A receptor antagonist 1 CPI-444 analog	Adenosine Receptor	Neurological Disease Cancer
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both **adenosine A_2A receptor** and A₁ receptor with K_i values of 4 and 264 nM, respectively .

HY-144672

A2A receptor antagonist 2	Adenosine Receptor	Inflammation/Immunology Cancer
A2A receptor antagonist 2 (Compound 57) is a potent, highly selective **adenosine A_2A receptor (A_2AR) antagonist with an IC₅₀** of 8.3 nM .

HY-148076

A2A receptor antagonist 3	Adenosine Receptor	Cancer
A2A receptor antagonist 3 (Example 92) is an **adenosine A2a receptor antagonist with a K_i** of 0.4 nM. A2A receptor antagonist 3 also binds to A2b, A1 and A3 receptor with K_is of 37, 107 and 1467 nM, respectively .

HY-13201

CGS 21680	Adenosine Receptor	Neurological Disease
CGS 21680 is a selective **adenosine A2A receptor agonist, with a K_i** of 27 nM.

HY-13201A

CGS 21680 Hydrochloride 5+ Cited Publications	Adenosine Receptor	Neurological Disease
CGS 21680 Hydrochloride is a selective **adenosine A2A receptor agonist with a K_i** of 27 nM.

HY-14409

Lu AA41063	Adenosine Receptor	Neurological Disease
Lu AA41063 is an adenosine A2A receptor antagonist that may be useful in the treatment of Parkinson's disease. Lu AA41063 has a Ki value of 5.9 nM and targets the human A2A receptor.

HY-A0168S

Regadenoson-d3 CVT-3146-d₃	Adenosine Receptor	Cardiovascular Disease Cancer
Regadenoson-d₃ is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with Kis of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents[1][2][3].

HY-10889

Preladenant 5+ Cited Publications SCH-420814	Adenosine Receptor	Neurological Disease Cancer
Preladenant is a potent and competitive antagonist of the human **adenosine A2A** receptor with a K_i of 1.1 nM and has over 1000-fold selectivity over other adenosine receptors.

HY-U00189

Sch412348	Adenosine Receptor	Neurological Disease
Sch412348 is a potent competitive antagonist of the human **adenosine A_2A** receptor (K_i=0.6 nM) and has >1000-fold selectivity over all other adenosine receptors.

HY-19533

SCH 58261 5+ Cited Publications	Adenosine Receptor	Cancer
SCH 58261 is a potent, selective and competitive antagonist of **adenosine A2A receptor with an IC₅₀** of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively .

HY-Z9063

1-epi-Regadenoson	Drug Metabolite	Others
1-epi-Regadenoson is an αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist .

HY-10888

Istradefylline 5+ Cited Publications KW-6002	Adenosine Receptor	Neurological Disease
Istradefylline is a very potent, selective and orally active **adenosine A2A receptor antagonist with K_i** of 2.2 nM in experimental models of Parkinson's disease.

HY-103183

CV1808 2-Phenylaminoadenosine	Adenosine Receptor Endogenous Metabolite	Inflammation/Immunology
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with K_is of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively .

HY-144064

Adenosine receptor antagonist 2	Adenosine Receptor	Cancer
Adenosine receptor antagonist 2 is an orally active **A2a/A2b adenosine receptor antagonist with IC₅₀*s of 1 nM and 3 nM, respectively. Adenosine* receptor antagonist 2 has anti-tumor activity .

HY-19310

AMP-579	Adenosine Receptor	Cardiovascular Disease Metabolic Disease
AMP-579 is an **adenosine receptor** agonist that primarily targets adenosine A1 and *A2_A* receptors (with K_i values of 1.7 and 4.5 nM for the A1 receptor in rat brain and adipocytes, and a K_i value of 56 nM for the *A2_A* receptor in rat brain). AMP-579 inhibits lipolysis, restores insulin-dependent glucose transport, and reduces heart rate through the activation of A1 receptors, while it induces vasodilation, particularly in coronary arteries, through the activation of *A2_A* receptors (with an IC₅₀ of 0.3 μM in porcine coronary arterial rings). AMP 579 shows potential for application in cardioprotection and the treatment of acute myocardial infarction .

HY-10857

Vipadenant 1 Publications Verification BIIB-014; CEB-4520	Adenosine Receptor	Neurological Disease
Vipadenant (BIIB-014; CEB-4520) is an **adenosine receptor antagonist, with K_i*s of 1.3 nM and 68 nM for A_2A* and A₁, respectively.

HY-Z9064

1-epi-Regadenoson ethyl ester	Others	Others
1-epi-Regadenoson ethyl ester is an intermediate in the synthesis of αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist .

HY-Z9065

1-epi-Regadenoson hydrazone	Others	Others
1-epi-Regadenoson hydrazone is an intermediate in the synthesis of αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist .

HY-14851

MRE 0094 Sonedenoson	Adenosine Receptor	Inflammation/Immunology
MRE 0094 (Sonedenoson) is a selective activator for **adenosine receptor A2A, with a K_i** of 490 nM. MRE 0094 exhibits anti-platelet and anti-inflammatory activities .

HY-19532

ZM241385 5+ Cited Publications	Adenosine Receptor	Neurological Disease Cancer
ZM241385 is a potent, high affinity and selective adenosine A_2a receptor (A_2AR) antagonist with a K_i value of 1.4 nM .

HY-147400

Sipagladenant KW-6356	Adenosine Receptor	Neurological Disease
Sipagladenant (Compound I) is an orally active **adenosine receptor A2A** inverse agonist . Sipagladenant can be used in frontal lobe dysfunction research .

HY-101978

Ciforadenant 5 Publications Verification CPI-444; V81444	Adenosine Receptor	Cancer
Ciforadenant (CPI-444) is a potent, orally active and selective **adenosine A2A receptor (A2AR**) antagonist, which induces antitumor responses .

HY-147541

A2A/A3 AR antagonist-1	Adenosine Receptor	Inflammation/Immunology
A2A/A3 AR antagonist-1 (compound 23) is a dual A_2A/A₃ adenosine receptor (AR) fluorescent ligand, with K_is of 90 nM and 31.8 nM for hA_2A AR and hA₃ AR, respectively .

HY-B0228S6

Adenosine-d2 Adenine riboside-d₂; D-adenosine-d₂	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-d₂ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

HY-B0228S7

Adenosine-d1-1 Adenine riboside-d₁-1; D-adenosine-d-1	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-d-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-B0228S8

Adenosine-d1-2 Adenine riboside-d₁-2; D-adenosine-d-2	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-d-2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-14365

TC-G 1004	Adenosine Receptor	Neurological Disease
TC-G 1004 (compound 16j) is an orally active **A_2A adenosine receptor antagonist, with K_i** values of 0.44 nM and 80 nM for hA_2A and hA₁, respectively .

HY-W088152

8-Bromotheophylline	Others	Others
8-Bromotheophylline can be used for the synthesis of the Oxazolo[2,3-f]purinediones, which are evaluated for their affinity at adenosine A₁ and A_2A receptors .

HY-100678

CGS 15943	Adenosine Receptor PI3K	Inflammation/Immunology Cancer
CGS 15943 is an orally bioavailable non-xanthine **Adenosine Receptor antagonist. Its K_i** for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. .

HY-B0228S4

Adenosine-1′-13C Adenine riboside-1′-¹³C; D-adenosine-1′-¹³C	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-1′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S2

Adenosine-2′-13C Adenine riboside-2′-¹³C; D-adenosine-2′-¹³C	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-2′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S3

Adenosine-3′-13C Adenine riboside-3′-¹³C; D-adenosine-3′-¹³C	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine-3′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S14

Adenosine-d9 Adenine riboside-d₉; D-adenosine-d₉	Isotope-Labeled Compounds	Others
Adenosine-d₉ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio .

HY-B0228S5

Adenosine-13C Adenine riboside-¹³C; D-adenosine-¹³C	Apoptosis Autophagy Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease Cancer
Adenosine- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

HY-14408

Lu AA47070	Adenosine Receptor	Neurological Disease
Lu AA47070 is a phosphonooxymethylene prodrug of a potent and selective Adenosine A2A receptor antagonist. Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade .

HY-101980

Imaradenant 3 Publications Verification HTL1071; AZD4635	Adenosine Receptor	Cancer
AZD4635 (HTL1071) is a potent, selective and orally active **adenosine A2A receptor (A2AR) antagonist. AZD4635 binds to human A2AR with a K_i** of 1.7 nM and shows >30-fold selectivity over other adenosine receptors .

HY-120652

A3AR antagonist 3	Adenosine Receptor	Inflammation/Immunology
A3AR antagonist 3 (compound 21) is a selective *A3 adenosine* receptor (A3AR) antagonist with a K_i** of 37 nM. A3AR antagonist 3 shows >60-fold selectivity in comparison to A1 and A2A adenosine receptors .

HY-103181

N6-Cyclopentyladenosine CPA; UK-80882	Adenosine Receptor	Neurological Disease
N6-Cyclopentyladenosine (CPA) is a selective **Adenosine A₁ receptor agonist, with K_i** values of 2.3 nM, 790 nM and 43 nM for human A₁, A_2A and A₃ receptors, respectively .

HY-N0092

Inosine 5+ Cited Publications	Adenosine Receptor Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-103183

CV1808 2-Phenylaminoadenosine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Adenosine Receptor Endogenous Metabolite
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with K_is of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively .

HY-N0092

Inosine 5+ Cited Publications	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

HY-124151

Adenosine-2'-monophosphate 2'-AMP; adenosine 2'-phosphate; AMP 2'-phosphate	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A_2A receptor activation .

HY-B0228

Adenosine 10+ Cited Publications Adenine riboside; D-adenosine	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Nucleoside Antimetabolite/Analog Autophagy Apoptosis Endogenous Metabolite
Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-B0228R

Adenosine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Nucleoside Antimetabolite/Analog Autophagy Apoptosis Endogenous Metabolite
Adenosine (Standard) is the analytical standard of Adenosine. This product is intended for research and analytical applications. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-N0092R

Inosine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors . In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A_2AR . Inosine dose-dependently induces hA_2AR-mediated ERK1/2 phosphorylation . Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes . In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice .

Cat. No.	Product Name	Chemical Structure

HY-B0228S6

Adenosine-d2
Adenosine-d₂ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

HY-B0228S8

Adenosine-d1-2
Adenosine-d-2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-B0228S4

Adenosine-1′-13C
Adenosine-1′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S5

Adenosine-13C
Adenosine- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

HY-A0168S

Regadenoson-d3

Regadenoson-d₃ is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with Kis of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents[1][2][3].

HY-B0228S7

Adenosine-d1-1
Adenosine-d-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-B0228S2

Adenosine-2′-13C
Adenosine-2′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S3

Adenosine-3′-13C
Adenosine-3′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S14

Adenosine-d9
Adenosine-d₉ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio .

HY-10888S

Istradefylline-13C,d3
Istradefylline- ¹³C,d₃ is the ¹³C- and deuterium labeled Istradefylline. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.

HY-B0228S

Adenosine-d1
Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

HY-N0092S

Inosine-2,8-d2
Inosine-2,8-d₂ is the deuterium labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors[1][2][3].

HY-B0228S1

Adenosine-13C5
Adenosine- ¹³C₅ is the ¹³C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].

HY-19532S

ZM241385-d7
ZM241385-d7 is a deuterated form of ZM241385 (HY-19532). ZM241385 is a potent, high affinity and selective adenosine A_2a receptor (A_2AR) antagonist with a K_i value of 1.4 nM .

HY-B0228S12

Adenosine-d13

Adenosine-d₁₃ (Adenine riboside-d₁₃; D-Adenosine-d₁₃) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-B0228S13

Adenosine-13C10

Adenosine- ¹³C₁₀ (Adenine riboside- ¹³C₁₀; D-Adenosine- ¹³C₁₀) is ¹³C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-B0228S11

Adenosine-15N5

Adenosine- ¹⁵N₅ (Adenine riboside- ¹⁵N₅; D-Adenosine- ¹⁵N₅) is the ¹⁵N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-N0092S3

Inosine-13C10,15N4
Inosine-13C10,15N4 is ¹³C and ¹⁵N labeled Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

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