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anti-influenza virus activity

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46

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14

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7

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14818A
    Laninamivir octanoate

    CS-8958

    		 Influenza Virus Infection
    Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .
    Laninamivir octanoate
  • HY-B0272
    Rifampicin
    20+ Cited Publications

    Rifampin; Rifamycin AMP

    		 Bacterial Influenza Virus Antibiotic Orthopoxvirus Infection Cancer
    Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.
    Rifampicin
  • HY-B0272S2
    Rifampicin-d4

    Rifampin-d4; Rifamycin AMP-d4

    		 Bacterial Influenza Virus Antibiotic Infection
    Rifampicin-d4 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
    Rifampicin-d4
  • HY-168510
    ATV03

    		Influenza Virus Infection
    ATV03 is an anti-influenza virus agent with excellent anti-influenza A and B virus activity. ATV03 inhibits anti-influenza A (H3N2) and anti-influenza B with EC50 values of 0.78 nM and 2.02 nM, respectively. ATV03 exerts anti-influenza activity by inhibiting polymerase acidic protein (PA) and RNA-dependent RNA polymerase (RdRp), as well as disrupting nuclear protein .
    ATV03
  • HY-14818C
    Laninamivir octanoate hydrate

    CS-8958 hydrate

    		 Influenza Virus Infection
    Laninamivir octanoate hydrate (CS-8958 hydrate), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate hydrate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .
    Laninamivir octanoate hydrate
  • HY-147974
    HSP90-IN-14

    		HSP Influenza Virus Infection
    HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively .
    HSP90-IN-14
  • HY-122261
    Spiroamantadine

    DU-34569 maleate

    		 Others Infection
    Spiroamantadine (DU-34569 maleate) is a compound related to Amantadine (HY-B0402) with anti-influenza virus activity .
    Spiroamantadine
  • HY-W013794
    Salcomine

    N,N′-Bis(salicylidene)ethylenediaminocobalt(II)

    		 Others Infection
    Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O2 and oxidation catalysts. Salcomine has anti-influenza virus activity .
    Salcomine
  • HY-165142
    Aureonitol

    		Others Others
    Aureonitol is a compound isolated from fungi that has anti-influenza activity by inhibiting the surface glycoprotein hemagglutinin of influenza virus and has potential value for compound development.
    Aureonitol
  • HY-149263
    HAA-09

    		Influenza Virus Virus Protease Infection
    HAA-09 is an orally active and potent anti-influenza agent, targeting the influenza PB2_cap binding domain. HAA-09 displays potent anti-influenza A virus activity, with an EC50 of 0.03 μM. HAA-09 shows polymerase inhibition, with an IC50 of 0.06±0.004 μM. HAA-09 blocks virus replication without causing obvious cytotoxicity .
    HAA-09
  • HY-15230
    Geldanamycin
    20+ Cited Publications

    		 HSP Bacterial Influenza Virus Antibiotic Infection Inflammation/Immunology Cancer
    Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.
    Geldanamycin
  • HY-B0272S
    Rifampicin-d3

    Rifampin-d3; Rifamycin AMP-d3

    		 Bacterial Influenza Virus Antibiotic Infection
    Rifampicin-d3 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities[1][2].
    Rifampicin-d3
  • HY-B0272S1
    Rifampicin-d8

    Rifampin-d8; Rifamycin AMP-d8

    		 Bacterial Influenza Virus Antibiotic Infection
    Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.
    Rifampicin-d8
  • HY-161983
    Neuraminidase-IN-22

    		Influenza Virus Infection
    Neuraminidase-IN-22 (compound 3e) is a potent, selective and orally active neuraminidase inhibitor with an IC50 value of 0.03 µM. Neuraminidase shows cytotoxicity and anti-influenza A virus activity .
    Neuraminidase-IN-22
  • HY-143492
    Influenza virus-IN-1

    		Influenza Virus Inflammation/Immunology
    Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities .
    Influenza virus-IN-1
  • HY-143493
    Influenza virus-IN-2

    		Influenza Virus Inflammation/Immunology
    Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities .
    Influenza virus-IN-2
  • HY-B0272R
    Rifampicin (Standard)

    Rifampin (Standard); Rifamycin AMP (Standard)

    		 Bacterial Influenza Virus Antibiotic Orthopoxvirus Infection Cancer
    Rifampicin (Standard) is the analytical standard of Rifampicin. This product is intended for research and analytical applications. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.
    Rifampicin (Standard)
  • HY-N6025
    Clemastanin B

    		Influenza Virus Infection Inflammation/Immunology
    Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .
    Clemastanin B
  • HY-N2264
    Wulignan A1

    		Influenza Virus Infection
    Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu agent resistant virus strain) activities .
    Wulignan A1
  • HY-14904A
    Umifenovir hydrochloride
    5+ Cited Publications

    		 Influenza Virus SARS-CoV Infection
    Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .
    Umifenovir hydrochloride
  • HY-N0224A
    Goitrin

    (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone

    		 Influenza Virus Metabolic Disease
    Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
    Goitrin
  • HY-15230R
    Geldanamycin (Standard)

    		HSP Bacterial Influenza Virus Antibiotic Infection Inflammation/Immunology Cancer
    Geldanamycin (Standard) is the analytical standard of Geldanamycin. This product is intended for research and analytical applications. Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.
    Geldanamycin (Standard)
  • HY-14904
    Umifenovir
    5+ Cited Publications

    		 SARS-CoV Influenza Virus Infection
    Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells . Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro . Umifenovir shows anti-inflammatory activity .
    Umifenovir
  • HY-147654
    PROTAC Hemagglutinin Degrader-1

    		PROTACs Influenza Virus Infection
    PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity .
    PROTAC Hemagglutinin Degrader-1
  • HY-162793
    RdRP-IN-8

    		Influenza Virus Infection
    RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM) .
    RdRP-IN-8
  • HY-14904AS
    Umifenovir-d6 hydrochloride

    		Isotope-Labeled Compounds Influenza Virus SARS-CoV Infection
    Umifenovir-d6 (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3].
    Umifenovir-d6 hydrochloride
  • HY-15511
    Tyrphostin A9
    3 Publications Verification

    Tyrphostin 9; Malonoben

    		 VEGFR Influenza Virus PDGFR Infection Cancer
    Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities.
    Tyrphostin A9
  • HY-14904AR
    Umifenovir hydrochloride (Standard)

    		Influenza Virus SARS-CoV Infection
    Umifenovir (hydrochloride) (Standard) is the analytical standard of Umifenovir (hydrochloride). This product is intended for research and analytical applications. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .
    Umifenovir hydrochloride (Standard)
  • HY-B0272S3
    Rifampicin-d11

    Rifampin-d11; Rifamycin AMP-d11

    		 Isotope-Labeled Compounds Others
    Rifampicin-d11 (Rifampin-d11; Rifamycin AMP-d11)is the deuterium labeledRifampicin(HY-B0272) . Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity .
    Rifampicin-d11
  • HY-155476
    Influenza virus-IN-8

    		Influenza Virus Infection
    Influenza virus-IN-8 (compound A4) is an inhibitor of influenza virus (Influenza Virus) that induces viral nucleoprotein (NP) aggregation and prevents its nuclear accumulation. Influenza virus-IN-8 has broad-spectrum anti-influenza activity and can inhibit the replication and transcription of influenza A virus. Influenza virus-IN-8 also inhibits Oseltamivir (HY-13317)-resistant H1N1/pdm09 strains .
    Influenza virus-IN-8
  • HY-14904R
    Umifenovir (Standard)

    		SARS-CoV Influenza Virus Infection
    Umifenovir (Standard) is the analytical standard of Umifenovir. This product is intended for research and analytical applications. Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells . Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro . Umifenovir shows anti-inflammatory activity .
    Umifenovir (Standard)
  • HY-N0482
    Phillyrin
    4 Publications Verification

    		 Cytochrome P450 Influenza Virus Bacterial Infection Inflammation/Immunology Cancer
    Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .
    Phillyrin
  • HY-10964
    Vadimezan
    40+ Cited Publications

    DMXAA; ASA-404

    		 STING IFNAR Influenza Virus Infection Cancer
    Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan has anti-influenza virus H1N1-PR8 activities.
    Vadimezan
  • HY-107201
    β-Cyclodextrin
    5+ Cited Publications

    Betadex

    		 Influenza Virus Infection
    β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.
    β-Cyclodextrin
  • HY-163659
    Anti-Influenza agent 6

    		Influenza Virus Infection
    Anti-Influenza agent 6 (compound 19b) shows inhibitory activity against A/WSN/33/H1N1 (EC50 = 0.015 μM) and influenza B virus Yamagata/16/88 (EC50 = 0.073 μM) and Victotis/2/87 (EC50 = 0.067 μM) .
    Anti-Influenza agent 6
  • HY-N0761
    Isoferulic acid

    3-Hydroxy-4-methoxycinnamic acid

    		 Adrenergic Receptor Influenza Virus Infection Metabolic Disease Endocrinology
    Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities.
    Isoferulic acid
  • HY-N0482R
    Phillyrin (Standard)

    		Cytochrome P450 Influenza Virus Bacterial Infection Inflammation/Immunology Cancer
    Phillyrin (Standard) is the analytical standard of Phillyrin. This product is intended for research and analytical applications. Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .
    Phillyrin (Standard)
  • HY-N0440
    Germacrone
    1 Publications Verification

    		 Influenza Virus Infection
    Germacrone is isolated from turmeric and has anti-influenza virus, anti-cancer, and neuroprotective activity. Germacrone inhibits the proliferation of human hepatoma cell lines by downregulating CDK1 and Bcl-2/Bcl-xl and upregulating p21 and Bax, leading to cell cycle arrest in the G2/M phase and apoptosis. Germacrone targets H1N1 and H3N2 influenza A viruses as well as influenza B viruses, significantly reducing viral titers in the lungs in animal models .
    Germacrone
  • HY-135646
    Eleutheroside B1

    		Influenza Virus Infection Inflammation/Immunology
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .
    Eleutheroside B1
  • HY-B0215
    Acetylcysteine
    Maximum Cited Publications
    397 Publications Verification

    N-Acetylcysteine; N-Acetyl-L-cysteine; NAC

    		 Reactive Oxygen Species Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis Infection Neurological Disease Cancer
    Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ​​is the most stable form of cysteine ​​during drug delivery and can be used in disulfidptosis studies .
    Acetylcysteine
  • HY-125798
    2,3-Dehydro-2-deoxy-N-acetylneuraminic acid
    2 Publications Verification

    Neu5Ac2en; DANA

    		 Influenza Virus Infection
    N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
    2,3-Dehydro-2-deoxy-N-acetylneuraminic acid
  • HY-N0440R
    Germacrone (Standard)

    		Influenza Virus Infection
    Germacrone (Standard) is the analytical standard of Germacrone. This product is intended for research and analytical applications. Germacrone is isolated from turmeric and has anti-influenza virus, anti-cancer, and neuroprotective activity. Germacrone inhibits the proliferation of human hepatoma cell lines by downregulating CDK1 and Bcl-2/Bcl-xl and upregulating p21 and Bax, leading to cell cycle arrest in the G2/M phase and apoptosis. Germacrone targets H1N1 and H3N2 influenza A viruses as well as influenza B viruses, significantly reducing viral titers in the lungs in animal models .
    Germacrone (Standard)
  • HY-B0215S
    Acetylcysteine-d3

    N-Acetylcysteine-d3; N-Acetyl-L-cysteine-d3; NAC-d3

    		 Isotope-Labeled Compounds Reactive Oxygen Species Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis Infection Neurological Disease
    Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
    Acetylcysteine-d3
  • HY-B0215R
    Acetylcysteine (Standard)

    		Reactive Oxygen Species Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis Infection Neurological Disease Cancer
    Acetylcysteine (Standard) is the analytical standard of Acetylcysteine. This product is intended for research and analytical applications. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor . Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases . Acetylcysteine induces cell apoptosis . Acetylcysteine also has anti-influenza virus activities . In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
    Acetylcysteine (Standard)
  • HY-B0215S1
    Acetylcysteine-15N

    N-Acetylcysteine-15N; N-Acetyl-L-cysteine-15N; NAC-15N

    		 Isotope-Labeled Compounds Reactive Oxygen Species Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis Infection Neurological Disease
    Acetylcysteine- 15N (N-Acetylcysteine- 15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
    Acetylcysteine-15N
  • HY-162680
    OSC-GCDI(P)

    		Influenza Virus Infection
    OSC-GCDI(P) is a broad-spectrum orally active anti-influenza virus agent that exhibits significant inhibitory effects against both wild-type and Oseltamivir (HY-13317) resistant (H275Y) influenza virus strains in mouse infection models. OSC-GCDI(P) is capable of preventing not only wild-type influenza viruses but also OS-resistant variants with NA(H275Y) .
    OSC-GCDI(P)

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