Search Result
Results for "
carboxylated
" in MedChemExpress (MCE) Product Catalog:
30
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-131256A
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist [1] [2] .
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- HY-W005963
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Others
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Inflammation/Immunology
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Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro .
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- HY-W454945S
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N-Boc-piperazine-d8
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Isotope-Labeled Compounds
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Others
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tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1].
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- HY-33615
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
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- HY-E70124B
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- HY-E70124A
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- HY-E70124C
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- HY-131256
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist [1] [2] .
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- HY-149676
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Glucosidase
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Metabolic Disease
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α-Glucosidase-IN-42 (Compound 26) is a 9-O-berberrubine carboxylate derivative. α-Glucosidase-IN-42 has potent α-glucosidase inhibitory activities with an IC50 value in the range of 1.61 μM. α-Glucosidase-IN-42 can be used for the research of antidiabetic .
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- HY-W454729S
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4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC
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Isotope-Labeled Compounds
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Others
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tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate[1].
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- HY-W007997R
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Biochemical Assay Reagents
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Others
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Ethyl 3-amino-1H-pyrazole-4-carboxylate (Standard) is the analytical standard of Ethyl 3-amino-1H-pyrazole-4-carboxylate. This product is intended for research and analytical applications. Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W064677
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Others
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Others
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Methyl 5-hydroxy-1H-indole-3-carboxylate is a marine natural product with isocitrate lyase inhibitory activity. Methyl 5-hydroxy-1H-indole-3-carboxylate is found in Hyrtios erectus. Methyl 5-hydroxy-1H-indole-3-carboxylate can be used to study its interaction with specific biological targets .
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- HY-W052600
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ADC Linker
PROTAC Linkers
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Cancer
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Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
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- HY-W003696
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Tert-butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate
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PROTAC Linkers
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Cancer
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tert-Butyl 5-bromoisoindoline-2-carboxylate is a PROTAC Linker. tert-Butyl 5-bromoisoindoline-2-carboxylate can be used in synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) .
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- HY-79635
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Bacterial
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Infection
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Methyl indole-3-carboxylate is a natural product isolated from Sorangium cellulosum strain Soce895. Methyl indole-3-carboxylate shows a weak activity against the Gram-positive Nocardia sp with a MIC value of 33.33 μg/mL .
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- HY-W003793
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Others
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Cancer
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Ethyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with anti-tumor activity. Ethyl 6-bromo-1H-indole-3-carboxylate was isolated from the sponge Iotrochota purpurea collected in Indonesia. The structure of Ethyl 6-bromo-1H-indole-3-carboxylate was confirmed by spectroscopic methods and accurate mass measurements .
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- HY-32208S
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Isotope-Labeled Compounds
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Others
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
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- HY-159557
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- HY-40151
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1
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- HY-W019226
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ADC Linker
PROTAC Linkers
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Cancer
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Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Cbz-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
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- HY-138354
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PROTAC Linkers
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Cancer
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Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-137494
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GABA Receptor
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Neurological Disease
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Ethyl β-carboline-3-carboxylate (fl-CCE) is a ligand and short-acting antagonist of benzodiazepine receptors. Ethyl β-carboline-3-carboxylate did not affect cerebellar cGMP levels when used alone, but when taken together with Diazepam, it significantly inhibited the cGMP levels that were upregulated by Diazepam .
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- HY-N3288
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Others
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Others
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Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels .
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- HY-W098127S
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Isotope-Labeled Compounds
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Others
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Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate[1].
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- HY-W052289
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Others
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Cancer
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Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs) .
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- HY-78337
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Biochemical Assay Reagents
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Others
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Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002603
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Biochemical Assay Reagents
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Others
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Benzyl piperazine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-69111
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Biochemical Assay Reagents
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Others
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Ethyl oxazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W012071
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Biochemical Assay Reagents
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Others
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-34497
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Biochemical Assay Reagents
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Others
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Ethyl 3-trifluoromethylpyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-50301
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Biochemical Assay Reagents
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Others
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Ethyl 2-aminothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003995
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Biochemical Assay Reagents
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Others
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Ethyl 2-chloropyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002874
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Biochemical Assay Reagents
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Others
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Methyl 3-aminopyridine-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002625
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Biochemical Assay Reagents
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Others
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Ethyl 2-bromothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-138354A
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Biochemical Assay Reagents
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Others
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Pyrroline-5-carboxylate sodium participates in amino acid metabolism in organisms and is an intermediate product of proline biosynthesis and catabolism. During pathogen infection and abiotic stress
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- HY-W713923
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- HY-40146
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N-Boc-3-azetidinone
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003140
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W012802
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Biochemical Assay Reagents
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Others
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Methyl 1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008201
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W016739
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Biochemical Assay Reagents
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Others
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Methyl 1H-indole-6-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003177
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Biochemical Assay Reagents
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Others
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tert-Butyl 4-iodopiperidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W003321
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Biochemical Assay Reagents
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Others
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(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-76366
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Biochemical Assay Reagents
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Others
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(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-69260
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PROTAC Linkers
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Cancer
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tert-Butyl 4-formylpiperidine-1-carboxylate is the linker of PROTAC BRM/BRG1 degrader-3 (HY-168251) .
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- HY-N9156
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Others
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Others
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Methyl 1,6-dihydroxy-3-methylxanthone-8-carboxylate is a Xanthones product that can be isolated from the roots of Polygala tenuifolia Willd .
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- HY-42448
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- HY-W002386
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Biochemical Assay Reagents
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Others
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Ethyl 2-amino-4-methylthiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-34027
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Biochemical Assay Reagents
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Others
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Ethyl 5-methyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002128
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Biochemical Assay Reagents
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Others
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Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007997
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3-Amino-4-ethoxycarbonylpyrazole
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Biochemical Assay Reagents
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Others
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Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-76558
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Biochemical Assay Reagents
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Others
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007392
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Methyl 4-bromopyrrole-2-carboxylate
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Biochemical Assay Reagents
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Others
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Methyl 4-bromo-1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007685
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Biochemical Assay Reagents
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Others
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Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W002351
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Biochemical Assay Reagents
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Others
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Ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W087433
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- HY-W140616
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Others
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Others
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Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a 4-O-sulfamoyl-4-biphenyl based compound and can be used for synthesis of other compounds .
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![Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate](//file.medchemexpress.eu/product_pic/hy-w140616.gif)
- HY-149929
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Beta-lactamase
Bacterial
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Infection
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EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC50 of 7.7 .
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- HY-W140284S
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Isotope-Labeled Compounds
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Others
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6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
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![6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 hydrochloride](//file.medchemexpress.eu/product_pic/hy-w140284s.gif)
- HY-100924
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GABA Receptor
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Neurological Disease
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β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [ 3H]flunitrazepam and ethyl (3-[ 3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM. β-CCB exhibits proconvulsant and anxiogenic effects .
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- HY-Y0949
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Methyl furan-2-carboxylate
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Endogenous Metabolite
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Others
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Methyl 2-furoate (Methyl furan-2-carboxylate) is a building block in chemical synthesis. A flavoring agent in food. Found in cranberries, guava fruits, raisins and other fruits. Also present in baked potato, roasted filberts, roasted peanut, tomatoes, coffee, cocoa, okra, etc.
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- HY-N10590
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Deacetylalpinoside
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Others
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Others
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Arborescosidic acid (Deacetylalpinoside) is a carboxylated iridoid glucoside, that can be isolated from Veronica beccabunga (brooklime) .
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- HY-15992
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VEGFR
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Cancer
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BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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- HY-W009757
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Others
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Others
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Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate is an active compound, and can be used in the synthesis of 2-phenylthiomethyl-indole derivatives, 2-phenylthiomethyl-indole derivative is a 5-lipoxygenase (5-LO) inhibitor .
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- HY-W006635
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Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate
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PROTAC Linkers
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Cancer
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Bpin-Cyclohexene-COOEt (Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate) is a PROTAC linker belonging to the PEG class. Bpin-Cyclohexene-COOEt can be used to synthesize PROTAC molecules .
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- HY-79880
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1,1'-Carbonyldiimidazole
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Others
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Others
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N,N'-Carbonyldiimidazole is a highly reactive carboxylating agent. N,N'-Carbonyldiimidazole can be used as a coupling reagent .
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- HY-152372
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Nucleoside Antimetabolite/Analog
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Others
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Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-N9721
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Others
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Others
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Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate is a Phenols product that can be isolated from the roots of Polygala fallax .
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![Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate](//file.medchemexpress.eu/product_pic/hy-n9721.gif)
- HY-W158160
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Others
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Infection
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AGS1286 (sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate) is an organosulfur compound that serves as a model for investigating the impact of sulfur-containing compounds on enzymatic activities and metabolic pathways. Additionally, it has been employed to explore the regulatory effects of these compounds on bacterial growth and gene expression.
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- HY-139428
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Others
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Others
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Hydroxydehydro Nifedipine Carboxylate is an inactive metabolite formed by the oxidative biotransformation of Nifedipine (HY-B0284) in the human body .
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- HY-32291
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(S)-Methyl 5-oxopyrrolidine-2-carboxylate; L-Pyroglutamic acid methyl ester
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Others
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Others
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Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity .
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- HY-131579
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Drug Metabolite
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Inflammation/Immunology
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Deschloro Cetirizine Dihydrochloride is a Cetirizine impurity. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.
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- HY-15992S
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Isotope-Labeled Compounds
VEGFR
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Cancer
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BIBF 1202- 13C,d3 is the 13C- and deuterium labeled BIBF 1202. BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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- HY-12966
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- HY-D2318
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Fluorescent Dye
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Others
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Flipper-TR 5 is a Flipper probe that contains a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 can selectively label the plasma membrane and exhibits excellent mechanosensitivity, negligible cytotoxicity, and manageable phototoxicity .
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- HY-101884A
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Others
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Neurological Disease
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Biotinylated-D-lysine TFA is a conjugate of L-biotin and D-lysine, where the carboxylate of L-biotin is coupled with the ϵ-amine of D-lysine via a secondary amide bond. Biotinylated-D-lysine TFA is an isomer of the neuroanatomical tracer Biocyte.
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- HY-17042
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
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Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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- HY-17042A
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P071
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Histamine Receptor
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Inflammation/Immunology
Endocrinology
Cancer
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Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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- HY-W127452
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Biochemical Assay Reagents
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Others
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Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations.
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- HY-159651
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PROTACs
17β-HSD
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Cancer
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PTOTAC HSD17B13 degrader 1 (compound 1) is a PROTAC targeting 17β-HSD 13 (HSD17B13). PTOTAC HSD17B13 degrader 1 is composed of PROTAC target protein ligand HSD17B13 degrader 2 (HY-159662) (red part), PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate (HY-W003696) (black part) and E3 ubiquitin ligase ligand E3 ligase Ligand 31 (HY-159660) (blue part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is E3 Ligase Ligand-linker Conjugate 114 (HY-159661) [1] .
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- HY-P2831
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CESs
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Endogenous Metabolite
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Metabolic Disease
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Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
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- HY-D1643
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Biochemical Assay Reagents
|
Others
|
|
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca 2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand .
|
-
- HY-17042AS
-
|
|
Isotope-Labeled Compounds
Histamine Receptor
|
Inflammation/Immunology
|
|
Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
- HY-17042AS1
-
|
|
Isotope-Labeled Compounds
Histamine Receptor
|
Inflammation/Immunology
|
|
Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
- HY-101884
-
|
(+)-Biocytin
|
Endogenous Metabolite
|
Neurological Disease
|
|
Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ?-amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .
|
-
- HY-17042S
-
|
|
Histamine Receptor
|
Inflammation/Immunology
|
|
Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
- HY-17042S1
-
|
|
Histamine Receptor
|
Inflammation/Immunology
|
|
Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
- HY-17042R
-
|
|
Histamine Receptor
|
Inflammation/Immunology
Endocrinology
Cancer
|
|
Cetirizine (Standard) is the analytical standard of Cetirizine. This product is intended for research and analytical applications. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
|
-
- HY-17042AR
-
|
|
Histamine Receptor
|
Inflammation/Immunology
Endocrinology
Cancer
|
|
Cetirizine (dihydrochloride) (Standard) is the analytical standard of Cetirizine (dihydrochloride). This product is intended for research and analytical applications. Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
|
-
- HY-132994
-
|
|
Others
|
Others
|
|
TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
|
-
- HY-107767
-
|
DC 81
|
Antibiotic
Apoptosis
DNA/RNA Synthesis
|
Cancer
|
|
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
|
-
- HY-W018746
-
EDTA disodium
Maximum Cited Publications
9 Publications Verification
Ethylenediaminetetraacetic acid disodium
|
Biochemical Assay Reagents
|
Others
|
|
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-162816
-
|
|
PROTACs
MAP4K
|
Cancer
|
|
PROTAC PD-L1 degrader-2 (compound C3) is an orally effective PROTAC targeting HPK1 (DC50=21.26 nM). HPK1 is a negative regulator of T cell receptors, which can lead to T cell dysfunction after abnormal activation. PROTAC PD-L1 degrader-2 can inhibit SLP76 and NF-κB signaling pathways and inhibit MAPK signal transduction, and has anticancer activity and immune activation. PROTAC PD-L1 degrader-2 has a certain oral bioavailability and can be combined with PD-L1 antibody therapy to achieve a tumor growth inhibition rate of 65.58%. PROTAC PD-L1 degrader-2 is composed of E3 ligase ligand Thalidomide (HY-14658; blue part), PROTAC linker tert-Butyl 3-oxoazetidine-1-carboxylate (HY-40146; black part), and target protein ligand HPK1-IN-51 (HY-162842; red part); the activity control of the target protein ligand can be HPK1 ligand 1 (HY-162841) [1] .
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-
- HY-W250143
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
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-
- HY-W018746R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
EDTA (disodium) (Standard) is the analytical standard of EDTA (disodium). This product is intended for research and analytical applications. EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W250143
-
|
|
Dyes
|
|
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
|
-
- HY-D2318
-
|
|
Fluorescent Dyes/Probes
|
|
Flipper-TR 5 is a Flipper probe that contains a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 can selectively label the plasma membrane and exhibits excellent mechanosensitivity, negligible cytotoxicity, and manageable phototoxicity .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W003995
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 2-chloropyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007997R
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 3-amino-1H-pyrazole-4-carboxylate (Standard) is the analytical standard of Ethyl 3-amino-1H-pyrazole-4-carboxylate. This product is intended for research and analytical applications. Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78337
-
|
|
Biochemical Assay Reagents
|
|
Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002603
-
|
|
Biochemical Assay Reagents
|
|
Benzyl piperazine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-69111
-
|
|
Biochemical Assay Reagents
|
|
Ethyl oxazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012071
-
|
|
Biochemical Assay Reagents
|
|
(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-34497
-
|
|
Gene Sequencing and Synthesis
|
|
Ethyl 3-trifluoromethylpyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-50301
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 2-aminothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002874
-
|
|
Biochemical Assay Reagents
|
|
Methyl 3-aminopyridine-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002625
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 2-bromothiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W713923
-
|
|
Indicators
|
|
Methyl 9-maleinimido-8-methoxy-6,7-benzocumarin-3-carboxylate is a kind of biochemical reagent.
|
-
- HY-40146
-
|
N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003140
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012802
-
|
|
Biochemical Assay Reagents
|
|
Methyl 1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008201
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W016739
-
|
|
Biochemical Assay Reagents
|
|
Methyl 1H-indole-6-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003177
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 4-iodopiperidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003321
-
|
|
Biochemical Assay Reagents
|
|
(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76366
-
|
|
Biochemical Assay Reagents
|
|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002386
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 2-amino-4-methylthiazole-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-34027
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 5-methyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002128
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007997
-
|
3-Amino-4-ethoxycarbonylpyrazole
|
Biochemical Assay Reagents
|
|
Ethyl 3-amino-1H-pyrazole-4-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76558
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007392
-
|
Methyl 4-bromopyrrole-2-carboxylate
|
Biochemical Assay Reagents
|
|
Methyl 4-bromo-1H-pyrrole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007685
-
|
|
Biochemical Assay Reagents
|
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002351
-
|
|
Biochemical Assay Reagents
|
|
Ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127452
-
|
|
Drug Delivery
|
|
Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations.
|
-
- HY-W018746
-
|
Ethylenediaminetetraacetic acid disodium
|
Chelators
|
|
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-W018746R
-
|
|
Chelators
|
|
EDTA (disodium) (Standard) is the analytical standard of EDTA (disodium). This product is intended for research and analytical applications. EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-42448
-
-
- HY-P4557
-
|
|
Peptides
|
Others
|
|
H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W454945S
-
|
|
|
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1].
|
-
-
- HY-15992S
-
|
|
|
BIBF 1202- 13C,d3 is the 13C- and deuterium labeled BIBF 1202. BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM.
|
-
-
- HY-17042S
-
|
|
|
Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
-
- HY-17042S1
-
|
|
|
Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
-
- HY-W454729S
-
|
|
|
tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate[1].
|
-
-
- HY-32208S
-
|
|
|
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
|
-
-
- HY-W098127S
-
|
|
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate[1].
|
-
-
- HY-W140284S
-
|
|
|
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
|
-
-
- HY-17042AS
-
|
|
|
Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
-
- HY-17042AS1
-
|
|
|
Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-126271
-
|
|
|
Alkynes
|
|
PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-152372
-
|
|
|
Nucleosides and their Analogs
|
|
Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
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