Search Result
Results for "
isoflavone
" in MedChemExpress (MCE) Product Catalog:
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W006405
-
|
Estrogen Receptor/ERR
|
Cardiovascular Disease
Cancer
|
Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
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-
-
- HY-N3011
-
-
-
- HY-N11985
-
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Others
|
Others
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Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .
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-
-
- HY-W006405R
-
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Others
|
Cardiovascular Disease
Cancer
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Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
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-
-
- HY-N1135
-
-
-
- HY-N9193
-
-
-
- HY-N3743
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Dihydroalpinumisoflavone
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Others
|
Others
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Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate .
|
-
-
- HY-N3011R
-
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Others
|
Inflammation/Immunology
|
Iridin (Standard) is the analytical standard of Iridin. This product is intended for research and analytical applications. Iridin is an isoflavone isolated from Iris milesii .
|
-
-
- HY-W749558
-
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Others
|
Inflammation/Immunology
|
2 '-Hydroxyformononetin is an isoflavone compound. 2 '-Hydroxyformononetin may have anti-inflammatory and antioxidant activities .
|
-
-
- HY-N13180
-
|
Others
|
Others
|
8,3′-Dihydroxy-7,4′-dimethoxyisoflavone is an isoflavone compound that has the ability to enhance immune function .
|
-
-
- HY-N1634
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(±)-1''-O-Methylerythrinin F
|
Others
|
Others
|
Anagyroidisoflavone A is an isoflavones isolated from pods of laburnum anagyroides .
|
-
-
- HY-N3353
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-
-
- HY-N3857
-
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Others
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Others
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Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
|
-
-
- HY-N7655
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4',7-Dimethoxy-5-hydroxyisoflavone
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Others
|
Others
|
7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos .
|
-
-
- HY-N3448
-
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Others
|
Cancer
|
Isowigtheone is a cytotoxic isoflavone compound isolated from the root barks of Brosimum utile. Isowigtheone has the potential for the research of cancer diseases .
|
-
-
- HY-N11773
-
|
PPAR
|
Metabolic Disease
|
Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research .
|
-
-
- HY-N2134
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Puerarin apioside
|
Tyrosinase
|
Endocrinology
|
Mirificin (Puerarin apioside) is a isoflavone in Puerariae Lobatae Radix. Mirificin inhibits tyrosinase (TYR) with an IC50 of 12.66 μM .
|
-
-
- HY-N4073
-
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Others
|
Inflammation/Immunology
|
6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye .
|
-
-
- HY-13938
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Iretol
1 Publications Verification
|
Endogenous Metabolite
|
Metabolic Disease
|
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .
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-
-
- HY-N0018
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-
-
- HY-N4070
-
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Others
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Others
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6"-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM .
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-
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- HY-N4071
-
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Others
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Others
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6"-O-Acetyldaidzin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetyldaidzin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 8.2 μM .
|
-
-
- HY-N0018R
-
|
Mitochondrial Metabolism
Reverse Transcriptase
Aldehyde Dehydrogenase (ALDH)
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Others
|
Daidzin (Standard) is the analytical standard of Daidzin. This product is intended for research and analytical applications. Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .
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-
-
- HY-N0520
-
Calycosin-7-glucoside
|
Reactive Oxygen Species
|
Others
|
Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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-
-
- HY-N3921
-
|
Carboxylesterase (CES)
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Cancer
|
Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis .
|
-
-
- HY-N3354
-
8-prenylgenistein
|
Apoptosis
|
Cancer
|
Lupiwighteone is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway .
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-
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- HY-N7683
-
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Glycosidase
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Metabolic Disease
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Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes .
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-
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- HY-N2693
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-
-
- HY-N0520R
-
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Reactive Oxygen Species
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Others
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Calycosin-7-O-β-D-glucoside (Standard) is the analytical standard of Calycosin-7-O-β-D-glucoside. This product is intended for research and analytical applications. Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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-
-
- HY-N6885
-
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Others
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Cancer
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Puerarin-4'-O-β-D-glucopyranoside (compound 8) is a isoflavone from Pueraria lobata root (PLR). Puerarin-4'-O-β-D-glucopyranoside has estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells .
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-
-
- HY-N3127
-
|
Casein Kinase
PI3K
VEGFR
|
Metabolic Disease
|
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ) .
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-
-
- HY-126113
-
|
Flavivirus
Dengue Virus
Influenza Virus
HCV
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Infection
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KIN101 is a potent RNA viral inhibitor with IC50s of 2 μM, >5 μM for influenza virus and Dengue virus (DNV), respectively. KIN101, an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has broad-spectrum activity against RNA viruses .
|
-
-
- HY-B2171AR
-
|
Apoptosis
|
Infection
Cancer
|
Isoflavone (Standard) is the analytical standard of Isoflavone. This product is intended for research and analytical applications. Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
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- HY-N1993
-
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Cytochrome P450
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Metabolic Disease
|
5-Methyl-7-methoxyisoflavone is an orally active anti-oxidant with remyelinating activity. 5-Methyl-7-methoxyisoflavone inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. 5-Methyl-7-methoxyisoflavone is a non-steroidal anabolic isoflavone, used as a anabolic agent. 5-Methyl-7-methoxyisoflavone shows better potency increasing muscle mass and endurance than Ipriflavone (HY-N0094). 5-Methyl-7-methoxyisoflavone can be used for fat loss besides the maintenance of low cholesterol level and strengthen bones .
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-
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- HY-N2670
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7-Methoxy-2',4'-dihydroxy isoflavone
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Others
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Others
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5-Deoxycajanin (Compound 4) is a flavonoid and can be isolated from Eschscholtzia californica .
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-
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- HY-N4129
-
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Others
|
Inflammation/Immunology
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4''-methyloxy-Genistin, an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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-
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- HY-N4072
-
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Others
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Metabolic Disease
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6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind .
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- HY-N4204
-
-
-
- HY-N0019
-
-
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- HY-N0917
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-
-
- HY-N13220
-
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Others
|
Endocrinology
|
Soybean Extract is a soybean extract, and its components include: Isoflavone. Soybean Extract has an increased content of isoflavone aglycones after biotransformation, which is an estrogen-like bioactive compound with effective type I collagen enhancement. .
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-
-
- HY-N0094
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-
-
- HY-N4128
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Daidzein 7-O-Β-D-glucoside 4''-O-methylate
|
Others
|
Inflammation/Immunology
|
4''-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside 4''-O-methylate), an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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-
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- HY-124741
-
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Others
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Others
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Jamaicin is a natural isoflavone found in the grains of Millettia pachyloba (Leguminosae) .
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-
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- HY-W031126
-
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Others
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Others
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7-Hydroxyisoflavone (compound 3) is a natural isoflavone compound .
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-
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- HY-N4316
-
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Others
|
Endocrinology
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Flemiphilippinin A is a prenylated isoflavone that can be isolated from Flemingia philippinensis .
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-
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- HY-N0016
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-
-
- HY-N13216
-
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Others
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Others
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Red Clover Extract is the extract of Red Clover, with content of 8% , 20% , 40% Isoflavones.
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-
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- HY-N6984
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-
-
- HY-N7957
-
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Others
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Others
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Pratensein-7-O-β-D-glucopyranoside is a new isoflavone .
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-
- HY-N4074
-
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Others
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Others
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6"-O-Malonylglycitin is an isoflavone glycoside that can be isolated from Glycine max .
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- HY-N3389
-
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Others
|
Metabolic Disease
|
Licoisoflavone A is an isoflavone . Licoisoflavone A inhibits lipid peroxidation with an IC50 of 7.2 μM .
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-
- HY-N6819
-
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Others
|
Cancer
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Iristectorin B is an isoflavone from Iris tectorum, has anti-cancer activities in breast cancer .
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- HY-N3388
-
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Others
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Metabolic Disease
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Licoisoflavone B is an isoflavone . Licoisoflavone B inhibits lipid peroxidation with an IC50 of 2.7 μM.
|
-
- HY-N3125
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-
- HY-N6631
-
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AMPK
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Metabolic Disease
Cancer
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7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
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- HY-N1979
-
4'-O-Methylpuerarin
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Others
|
Metabolic Disease
|
4'-Methoxypuerarin (4'-O-Methylpuerarin), an isoflavone diglycoside, is isolated from Pueraria lobata .
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-
- HY-N4172
-
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Others
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Others
|
Tectorigenin 7-O-Xylosyl Glucoside is a glycosidic isoflavone isolated from Pueraria thomsonii flower .
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- HY-N2505
-
|
Others
|
Inflammation/Immunology
|
Iristectorigenin A is a natural isoflavone isolated from B. chinensis rhizomes. Iristectorigenin A shows antioxidant activity .
|
-
- HY-N0423
-
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Others
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Inflammation/Immunology
Cancer
|
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
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- HY-N0019S
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-
- HY-N1978
-
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Others
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Neurological Disease
|
3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.
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-
- HY-N3492
-
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Others
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Others
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Isoderrone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
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- HY-N3496
-
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Others
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Others
|
Isochandalone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
|
-
- HY-125670
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-
- HY-N4075
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-
- HY-119846
-
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Others
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Cancer
|
Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects .
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-
- HY-N2597
-
-
- HY-129899
-
-
- HY-N7680
-
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Others
|
Metabolic Disease
|
Neopuerarin A is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin A shows significant hepatoprotective effect .
|
-
- HY-N0019R
-
|
PPAR
Endogenous Metabolite
|
Endocrinology
Cancer
|
Daidzein (Standard) is the analytical standard of Daidzein. This product is intended for research and analytical applications. Daidzein is a soy isoflavone, which acts as a PPAR activator.
|
-
- HY-N0094R
-
|
Cytochrome P450
|
Metabolic Disease
Cancer
|
Ipriflavone (Standard) is the analytical standard of Ipriflavone. This product is intended for research and analytical applications. Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
|
-
- HY-N0019S1
-
-
- HY-N7680A
-
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Others
|
Metabolic Disease
|
Neopuerarin B is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin B shows significant hepatoprotective effect .
|
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- HY-N4194
-
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PPAR
|
Metabolic Disease
|
Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity .
|
-
- HY-N4244
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
|
Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation .
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- HY-100583A
-
-
- HY-133951
-
|
Bacterial
Fungal
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Infection
|
4',6,7-Trimethoxyisoflavone is an isoflavone with antimicrobial activities against a wide range of bacteria and fungi. 4',6,7-Trimethoxyisoflavone also has antioxidant effects .
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- HY-N0423R
-
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Others
|
Inflammation/Immunology
Cancer
|
Sophoricoside (Standard) is the analytical standard of Sophoricoside. This product is intended for research and analytical applications. Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
|
-
- HY-N3737
-
|
Aurora Kinase
PERK
Reactive Oxygen Species
|
Cancer
|
Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity .
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- HY-N0145R
-
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5-HT Receptor
|
Inflammation/Immunology
Cancer
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Puerarin (Standard) is the analytical standard of Puerarin. This product is intended for research and analytical applications. Puerarin, an isoflavone extracted from Radix puerariae, is a 5-HT2C receptor antagonist.
|
-
- HY-N8673
-
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Others
|
Others
|
3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one
is derived from natural Scilla nervosa subsp. rigidifolia of
isoflavone compounds .
|
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- HY-N1980
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
|
3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO•, total ROS scavenging activities .
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- HY-N0268
-
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NO Synthase
|
Inflammation/Immunology
|
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
|
-
- HY-14596
-
Genistein
Maximum Cited Publications
49 Publications Verification
NPI 031L
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
|
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- HY-N7335
-
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Others
|
Neurological Disease
Inflammation/Immunology
Cancer
|
Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities .
|
-
- HY-N5129
-
|
Others
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Others
|
Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .
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-
- HY-159811
-
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Others
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Cancer
|
Antitumor agent-187 (compound I) is an isoflavone derivative with antitumor activity. Antitumor agent-187 shows IC50 values of 5.23 μM and 2.63 μM on A2780 and SKOV3, respectily .
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- HY-N1978R
-
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Others
|
Neurological Disease
|
3'-Methoxypuerarin (Standard) is the analytical standard of 3'-Methoxypuerarin. This product is intended for research and analytical applications. 3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.
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- HY-N2412
-
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Chloride Channel
|
Neurological Disease
Cancer
|
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM) .
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- HY-N0791
-
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Estrogen Receptor/ERR
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Cancer
|
Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway .
|
-
- HY-N0595
-
Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
|
Estrogen Receptor/ERR
Apoptosis
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Metabolic Disease
Cancer
|
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
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- HY-N15219
-
|
Endogenous Metabolite
NO Synthase
|
Inflammation/Immunology
|
6-Hydroxygenistein-7-O-β-D-glucopyranoside (compound 2) is a glucopyranoside that can be isolated from Pueraria lobata flower. The isoflavones in Pueraria lobata flower are potential anti-inflammatory agents for microglia and can inhibit the production of NO .
|
-
- HY-N9134
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Isoprunetin
|
Glycosidase
|
Others
|
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast .
|
-
- HY-N0012
-
Glycitein 7-O-β-glucoside
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Bacterial
|
Infection
Cancer
|
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .
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-
- HY-W470415
-
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Microtubule/Tubulin
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Cancer
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Alfalone (compound 9ia) is an antimitotic agent. Alfalone causes cleavage arrest and initiates the formation of tuberculate eggs .
|
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- HY-14596R
-
NPI 031L (Standard)
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
|
-
- HY-N7382
-
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Bacterial
|
Infection
|
Laburnetin is a kind of isoflavone antibacterial agent. Laburnetin has antibacterial activity against fungi and S. vesicarium. Laburnetin intensifies the susceptibility of Methicillin (HY-121544) resistant Staphylococcus aureus (MRSA) strains to Methicillin. Laburnetin can be used to control pests of cultivated species .
|
-
- HY-N0268R
-
|
NO Synthase
|
Inflammation/Immunology
|
Irisflorentin (Standard) is the analytical standard of Irisflorentin. This product is intended for research and analytical applications. Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
|
-
- HY-14596S
-
NPI 031L-d4
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].
|
-
- HY-N0145
-
-
- HY-N1847
-
|
Sodium Channel
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Neurological Disease
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3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels .
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- HY-N1980R
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Reactive Oxygen Species
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Inflammation/Immunology
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3'-Hydroxypuerarin (Standard) is the analytical standard of 3'-Hydroxypuerarin. This product is intended for research and analytical applications. 3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO?, total ROS scavenging activities .
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- HY-N0595R
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Estrogen Receptor/ERR
Apoptosis
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Metabolic Disease
Cancer
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Genistin (Standard) is the analytical standard of Genistin. This product is intended for research and analytical applications. Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
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- HY-N0791R
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Estrogen Receptor/ERR
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Cancer
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Tectoridin (Standard) is the analytical standard of Tectoridin. This product is intended for research and analytical applications. Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway .
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- HY-N1280
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Amyloid-β
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Neurological Disease
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Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation .
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- HY-N0012R
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Bacterial
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Infection
Cancer
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Glycitin (Standard) is the analytical standard of Glycitin. This product is intended for research and analytical applications. Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .
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- HY-N0270
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Ononoside; Formononetin 7-O-β-D-glucopyranoside
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ERK
JNK
p38 MAPK
PI3K
Akt
mTOR
Apoptosis
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Neurological Disease
Metabolic Disease
Cancer
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Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy .
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- HY-N2692
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Others
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Cancer
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6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .
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- HY-N0270R
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Others
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Others
Neurological Disease
Cancer
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Ononin (Standard) is the analytical standard of Ononin. Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy .
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- HY-N13218
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Others
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Cardiovascular Disease
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Pueraria Extract is a kudzu extract, and its components include: Isoflavones. Pueraria Extract (ethanol extract) can significantly improve cardiac damage in rats with acute myocardial infarction. Pueraria Extract improves bile acid levels by increasing the expression of CYP7A1 and restoring the diversity of intestinal microbiota. Pueraria Extract can also inhibit the FXR-FGF15 signaling pathway and increase the expression of OST-α to increase bile acid reabsorption and fecal excretion. .
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- HY-N8477
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- HY-W753779
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8-OHG
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Reactive Oxygen Species
NO Synthase
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Others
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8-Hydroxygenistein (8-OHG) is an antioxidant that can effectively scavenge nitric oxide (NO) and superoxide anion (O₂⁻). 8-Hydroxygenistein belongs to ortho-dihydroxy isoflavones (ODI) and is abundantly present in dark soy sauce and light soy sauce. Its antioxidant activity is stronger than that of its parent compound genistein (HY-14596). The content of 8-Hydroxygenistein is positively correlated with the antioxidant capacity of soy sauce (r = 0.959), and it remains highly stable even after being heated in boiling water for 60 minutes. During the brewing and storage of soy sauce, 8-Hydroxygenistein effectively prevents oxidative damage, making it promising for use in food antioxidant research.
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-N0019S
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Daidzein-d4 is the deuterium labeled Daidzein. Daidzein is a soy isoflavone, which acts as a PPAR activator.
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- HY-14596S
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Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].
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- HY-N0019S1
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Daidzein-d6 is a deuterium labeled Daidzein (HY-N0019). Daidzein is a soy isoflavone, which acts as a PPAR activator.
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