Search Result
Results for "
isoflavone
" in MedChemExpress (MCE) Product Catalog:
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W006405
-
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Others
|
Others
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Isoflavone, a soy phytoestrogen and a biologically active component, presents in several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa .
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-
-
- HY-N3011
-
-
-
- HY-N1135
-
-
-
- HY-N9193
-
|
Others
|
Others
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2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone is an isoflavone .
|
-
-
- HY-N3743
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Dihydroalpinumisoflavone
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Others
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Others
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Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate .
|
-
-
- HY-N11985
-
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Others
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Others
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Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .
|
-
-
- HY-N1634
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(±)-1''-O-Methylerythrinin F
|
Others
|
Others
|
Anagyroidisoflavone A is an isoflavones isolated from pods of laburnum anagyroides .
|
-
-
- HY-N3353
-
-
-
- HY-N3857
-
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Others
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Others
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Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
|
-
-
- HY-N7655
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4',7-Dimethoxy-5-hydroxyisoflavone
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Others
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Others
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7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos .
|
-
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- HY-N3448
-
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Others
|
Cancer
|
Isowigtheone is a cytotoxic isoflavone compound isolated from the root barks of Brosimum utile. Isowigtheone has the potential for the research of cancer diseases .
|
-
-
- HY-N11773
-
|
PPAR
|
Metabolic Disease
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Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research .
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-
-
- HY-N2134
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Puerarin apioside
|
Tyrosinase
|
Endocrinology
|
Mirificin (Puerarin apioside) is a isoflavone in Puerariae Lobatae Radix. Mirificin inhibits tyrosinase (TYR) with an IC50 of 12.66 μM .
|
-
-
- HY-N4073
-
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Others
|
Inflammation/Immunology
|
6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye .
|
-
-
- HY-13938
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Iretol
1 Publications Verification
|
Endogenous Metabolite
|
Metabolic Disease
|
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .
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-
-
- HY-N0018
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-
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- HY-N4070
-
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Others
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Others
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6"-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM .
|
-
-
- HY-N4071
-
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Others
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Others
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6"-O-Acetyldaidzin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetyldaidzin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 8.2 μM .
|
-
-
- HY-N0520
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Calycosin-7-glucoside
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Reactive Oxygen Species
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Others
|
Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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-
-
- HY-N3921
-
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Others
|
Cancer
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Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis .
|
-
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- HY-N3354
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8-prenylgenistein
|
Apoptosis
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Cancer
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Lupiwighteone is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway .
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-
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- HY-N7683
-
|
Glucosidase
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Metabolic Disease
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Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes .
|
-
-
- HY-N2693
-
-
-
- HY-N1993
-
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Others
|
Metabolic Disease
|
5-Methyl-7-methoxyisoflavone is a non-steroidal anabolic isoflavone. 5-Methyl-7-methoxyisoflavone shows potency increasing muscle mass and endurance. 5-Methyl-7-methoxyisoflavone can be used for fat loss, increase vitality and muscle gain besides the maintenance of low cholesterol level and strengthen bones .
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-
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- HY-N6885
-
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Others
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Cancer
|
Puerarin-4'-O-β-D-glucopyranoside (compound 8) is a isoflavone from Pueraria lobata root (PLR). Puerarin-4'-O-β-D-glucopyranoside has estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells .
|
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- HY-N3127
-
|
Casein Kinase
PI3K
VEGFR
|
Metabolic Disease
|
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ) .
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- HY-126113
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Flavivirus
Dengue virus
Influenza Virus
HCV
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Infection
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KIN101 is a potent RNA viral inhibitor with IC50s of 2 μM, >5 μM for influenza virus and Dengue virus (DNV), respectively. KIN101, an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has broad-spectrum activity against RNA viruses .
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-
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- HY-N2670
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7-Methoxy-2',4'-dihydroxy isoflavone
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Others
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Others
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5-Deoxycajanin (Compound 4) is a flavonoid and can be isolated from Eschscholtzia californica .
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-
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- HY-N4129
-
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Others
|
Inflammation/Immunology
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4''-methyloxy-Genistin, an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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-
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- HY-N4072
-
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Others
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Metabolic Disease
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6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind .
|
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-
- HY-N0019
-
-
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- HY-N0917
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-
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- HY-N0270
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Ononin
5 Publications Verification
Ononoside; Formononetin 7-O-β-D-glucopyranoside
|
Others
|
Others
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Ononin is an isoflavone that inhibits the growth of Pluchea lanceolata in soil.
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-
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- HY-N4204
-
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Others
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Cancer
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Daidzein diacetate is a derivative of Daidzein that is a soy isoflavone .
|
-
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- HY-N0094
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-
-
- HY-N4128
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Daidzein 7-O-Β-D-glucoside 4''-O-methylate
|
Others
|
Inflammation/Immunology
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4''-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside 4''-O-methylate), an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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-
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- HY-N4316
-
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Others
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Endocrinology
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Flemiphilippinin A is a prenylated isoflavone that can be isolated from Flemingia philippinensis .
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- HY-124741
-
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Others
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Others
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Jamaicin is a natural isoflavone found in the grains of Millettia pachyloba (Leguminosae) .
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-
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- HY-W031126
-
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Others
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Others
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7-Hydroxyisoflavone (compound 3) is a natural isoflavone compound .
|
-
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- HY-N0016
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-
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- HY-N6984
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-
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- HY-N7957
-
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Others
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Others
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Pratensein-7-O-β-D-glucopyranoside is a new isoflavone .
|
-
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- HY-N3389
-
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Others
|
Metabolic Disease
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Licoisoflavone A is an isoflavone . Licoisoflavone A inhibits lipid peroxidation with an IC50 of 7.2 μM .
|
-
-
- HY-N4074
-
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Others
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Others
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6"-O-Malonylglycitin is an isoflavone glycoside that can be isolated from Glycine max .
|
-
-
- HY-N6631
-
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AMPK
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Metabolic Disease
Cancer
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7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
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-
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- HY-N3125
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-
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- HY-N6819
-
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Others
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Cancer
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Iristectorin B is an isoflavone from Iris tectorum, has anti-cancer activities in breast cancer .
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-
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- HY-N3388
-
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Others
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Metabolic Disease
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Licoisoflavone B is an isoflavone . Licoisoflavone B inhibits lipid peroxidation with an IC50 of 2.7 μM.
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-
-
- HY-N0423
-
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Others
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Inflammation/Immunology
Cancer
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Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
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-
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- HY-N0019S
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-
- HY-N4172
-
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Others
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Others
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Tectorigenin 7-O-Xylosyl Glucoside is a glycosidic isoflavone isolated from Pueraria thomsonii flower .
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- HY-N1979
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4'-O-Methylpuerarin
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Others
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Metabolic Disease
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4'-Methoxypuerarin (4'-O-Methylpuerarin), an isoflavone diglycoside, is isolated from Pueraria lobata .
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- HY-N2505
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Others
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Inflammation/Immunology
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Iristectorigenin A is a natural isoflavone isolated from B. chinensis rhizomes. Iristectorigenin A shows antioxidant activity .
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- HY-N0145
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- HY-N1978
-
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Others
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Neurological Disease
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3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.
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- HY-N3492
-
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Others
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Others
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Isoderrone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
|
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- HY-N3496
-
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Others
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Others
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Isochandalone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
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- HY-125670
-
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Others
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Inflammation/Immunology
Cancer
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Lanceolarin is an isoflavone compound isolated from the Andira inermis plant with anti-inflammatory, antioxidant and anti-tumor activities .
|
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- HY-N2597
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- HY-N4075
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- HY-119846
-
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Others
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Cancer
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Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects .
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- HY-N7680
-
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Others
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Metabolic Disease
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Neopuerarin A is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin A shows significant hepatoprotective effect .
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- HY-N0019R
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PPAR
Endogenous Metabolite
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Endocrinology
Cancer
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Daidzein (Standard) is the analytical standard of Daidzein. This product is intended for research and analytical applications. Daidzein is a soy isoflavone, which acts as a PPAR activator.
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- HY-N0019S1
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- HY-N0094R
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Others
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Metabolic Disease
Cancer
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Ipriflavone (Standard) is the analytical standard of Ipriflavone. This product is intended for research and analytical applications. Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
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- HY-N7680A
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Others
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Metabolic Disease
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Neopuerarin B is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin B shows significant hepatoprotective effect .
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- HY-N4244
-
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Reactive Oxygen Species
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Inflammation/Immunology
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Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation .
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- HY-N4194
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PPAR
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Metabolic Disease
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Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity .
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- HY-100583A
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-
- HY-133951
-
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Bacterial
Fungal
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Infection
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4',6,7-Trimethoxyisoflavone is an isoflavone with antimicrobial activities against a wide range of bacteria and fungi. 4',6,7-Trimethoxyisoflavone also has antioxidant effects .
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- HY-N3737
-
|
Aurora Kinase
PERK
Reactive Oxygen Species
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Cancer
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Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity .
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- HY-14596
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Genistein
Maximum Cited Publications
39 Publications Verification
NPI 031L
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
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- HY-N1980
-
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Reactive Oxygen Species
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Inflammation/Immunology
|
3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO•, total ROS scavenging activities .
|
-
- HY-N0268
-
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NO Synthase
|
Inflammation/Immunology
|
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
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- HY-N8673
-
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Others
|
Others
|
3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one
is derived from natural Scilla nervosa subsp. rigidifolia of
isoflavone compounds .
|
-
- HY-N7335
-
|
Others
|
Neurological Disease
Inflammation/Immunology
Cancer
|
Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities .
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-
- HY-N5129
-
|
Others
|
Others
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Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .
|
-
- HY-N0595
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Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
|
Estrogen Receptor/ERR
Apoptosis
|
Metabolic Disease
Cancer
|
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
|
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- HY-N2412
-
|
Chloride Channel
|
Neurological Disease
Cancer
|
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM) .
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-
- HY-N0791
-
|
Estrogen Receptor/ERR
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Cancer
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Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway .
|
-
- HY-N9134
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Isoprunetin
|
Glucosidase
|
Others
|
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast .
|
-
- HY-N0012
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Glycitein 7-O-β-glucoside
|
Bacterial
|
Infection
Cancer
|
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .
|
-
- HY-14596S
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NPI 031L-d4
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].
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- HY-N7382
-
|
Bacterial
|
Infection
|
Laburnetin is a kind of isoflavone antibacterial agent. Laburnetin has antibacterial activity against fungi and S. vesicarium. Laburnetin intensifies the susceptibility of Methicillin (HY-121544) resistant Staphylococcus aureus (MRSA) strains to Methicillin. Laburnetin can be used to control pests of cultivated species .
|
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- HY-14596R
-
NPI 031L (Standard)
|
EGFR
Autophagy
Apoptosis
Endogenous Metabolite
|
Cancer
|
Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
|
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- HY-N1847
-
|
Sodium Channel
|
Neurological Disease
|
3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels .
|
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- HY-N1280
-
|
Amyloid-β
|
Neurological Disease
|
Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation .
|
-
- HY-N2692
-
|
Others
|
Cancer
|
6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .
|
-
- HY-N8477
-
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N0019S
-
|
Daidzein-d4 is the deuterium labeled Daidzein. Daidzein is a soy isoflavone, which acts as a PPAR activator.
|
-
-
- HY-N0019S1
-
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Daidzein-d6 is a deuterium labeled Daidzein (HY-N0019). Daidzein is a soy isoflavone, which acts as a PPAR activator.
|
-
-
- HY-14596S
-
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Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].
|
-
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