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Results for "

polycyclic

" in MedChemExpress (MCE) Product Catalog:

57

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3

Fluorescent Dye

2

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8

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16

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6

Isotope-Labeled Compounds

1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013570
    Acenaphthylene
    1 Publications Verification

    		 Others Others
    Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .
    Acenaphthylene
  • HY-23498
    Benzo[k]fluoranthene

    		Endogenous Metabolite Others
    Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic and genotoxic .
    Benzo[k]fluoranthene
  • HY-W014075
    1-Hydroxypyrene

    		Endogenous Metabolite Metabolic Disease
    1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes .
    1-Hydroxypyrene
  • HY-W834359
    (±)-Longamide

    		Indoleamine 2,3-Dioxygenase (IDO) Endogenous Metabolite Others
    (±)-Longamide is a polycyclic bioactive metabolite that can be isolated from sponges and features a bromopyrrole fragment .
    (±)-Longamide
  • HY-W013570R
    Acenaphthylene (Standard)

    		Others Others
    Acenaphthylene (Standard) is the analytical standard of Acenaphthylene. This product is intended for research and analytical applications. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .
    Acenaphthylene (Standard)
  • HY-N11501
    7-epi-Isogarcinol

    		STAT Apoptosis Cancer
    7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration .
    7-epi-Isogarcinol
  • HY-23498R
    Benzo[k]fluoranthene (Standard)

    		Endogenous Metabolite Others
    Benzo[k]fluoranthene (Standard) is the analytical standard of Benzo[k]fluoranthene. This product is intended for research and analytical applications. Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic and genotoxic .
    Benzo[k]fluoranthene (Standard)
  • HY-162541
    α-Glucosidase-IN-64

    		Glycosidase Metabolic Disease
    α-Glucosidase-IN-64 (compound 10) is a potent α-glucosidase inhibitor with an IC50 value of 8.62 µM. α-Glucosidase-IN-64 is a polycyclic polyprenylated acylphloroglucinol that can be isolated from hypericum beanii .
    α-Glucosidase-IN-64
  • HY-W026772R
    Fluorene (Standard)

    		Fluorescent Dye Others
    Fluorene (Standard) is the analytical standard of Fluorene. This product is intended for research and analytical applications. Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative?can be used as a precursor to fluorene-based dyes .
    Fluorene (Standard)
  • HY-W014075R
    1-Hydroxypyrene (Standard)

    		Endogenous Metabolite Metabolic Disease
    1-Hydroxypyrene (Standard) is the analytical standard of 1-Hydroxypyrene. This product is intended for research and analytical applications. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes .
    1-Hydroxypyrene (Standard)
  • HY-143770
    Cap-dependent endonuclease-IN-16

    		Influenza Virus Infection
    Cap-dependent endonuclease-IN-16 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative. Cap-dependent endonuclease-IN-16 has the potential for the research of influenza (extracted from patent CN112778330A, compound 15A) .
    Cap-dependent endonuclease-IN-16
  • HY-23499
    Indeno[1,2,3-cd]pyrene

    		Aryl Hydrocarbon Receptor Inflammation/Immunology Cancer
    Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor .
    Indeno[1,2,3-cd]pyrene
  • HY-N2427
    Adamantane

    		Others Others
    Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
    Adamantane
  • HY-125630
    Decacyclene

    		Others Others
    Decacyclene is a large polycyclic aromatic hydrocarbon with a triple symmetry. Decacyclene is a three-blade molecular propeller in the solid state, and crystal structure analysis shows that the molecule has a non-planar twisted form, and the crystal is chiral, which may correspond to the enantiomers of the Decacyclene propeller. Decacyclene can be used for research in chemical synthesis and materials science .
    Decacyclene
  • HY-23499R
    Indeno[1,2,3-cd]pyrene (Standard)

    		Aryl Hydrocarbon Receptor Inflammation/Immunology Cancer
    Indeno[1,2,3-cd]pyrene (Standard) is the analytical standard of Indeno[1,2,3-cd]pyrene. This product is intended for research and analytical applications. Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor .
    Indeno[1,2,3-cd]pyrene (Standard)
  • HY-W013053
    Dibenz[a,h]anthracene

    DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene

    		 DNA/RNA Synthesis Apoptosis MDM-2/p53 Cancer
    Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms .
    Dibenz[a,h]anthracene
  • HY-N2427R
    Adamantane (Standard)

    		Others Others
    Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
    Adamantane (Standard)
  • HY-W013053R
    Dibenz[a,h]anthracene (Standard)

    		DNA/RNA Synthesis Apoptosis MDM-2/p53 Cancer
    Dibenz[a,h]anthracene (Standard) is the analytical standard of Dibenz[a,h]anthracene. This product is intended for research and analytical applications. Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms .
    Dibenz[a,h]anthracene (Standard)
  • HY-111441
    1,4-Chrysenequinone

    Chrysene-1,4-dione

    		 Aryl Hydrocarbon Receptor Cancer
    1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).
    1,4-Chrysenequinone
  • HY-121107
    Chrysene
    1 Publications Verification

    		 Biochemical Assay Reagents Cancer
    Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties .
    Chrysene
  • HY-W026772
    Fluorene
    1 Publications Verification

    		 Fluorescent Dye Reactive Oxygen Species TNF Receptor Interleukin Related SOD Inflammation/Immunology
    Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders .
    Fluorene
  • HY-W011845
    DMBA

    7,12-DMBA; 7,12-Dimethylbenzanthracene

    		 Others Cancer
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
    DMBA
  • HY-W007692
    Acetylpyrazine

    2-Acetylpyrazine

    		 Drug Intermediate Others
    Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
    Acetylpyrazine
  • HY-33451
    4-Dibenzofurancarboxylic acid

    		Biochemical Assay Reagents Others
    4-Dibenzofurancarboxylic acid is one of the synthesis materials of polycyclic aromatic hydrocarbons (PAHs) and Schistosoma mansoni histone deacetylase 8 (smHDAC8) inhibitors .
    4-Dibenzofurancarboxylic acid
  • HY-121107S
    Chrysene-d12

    		Isotope-Labeled Compounds Cancer
    Chrysene-d12 is the deuterium labeled Chrysene. Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties[1].
    Chrysene-d12
  • HY-121360
    Cylindrospermopsin

    		DNA/RNA Synthesis Others
    Cylindrospermopsin is a cyanotoxin produced by a variety of freshwater cyanobacteria. It is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA .
    Cylindrospermopsin
  • HY-P10672
    SEI144

    		Biochemical Assay Reagents Others
    SEI144 is a low nanomolar binder of USP15 and does not inhibit USP15 activity .
    SEI144
  • HY-W441021
    DSPE-Pyrene

    		Liposome Others
    DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
    DSPE-Pyrene
  • HY-B1727
    Phenanthrene
    1 Publications Verification

    		 Apoptosis Inflammation/Immunology Cancer
    Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment .
    Phenanthrene
  • HY-136301
    Acid secretion-IN-1

    		Others Inflammation/Immunology
    Acid secretion-IN-1 is a polycyclic compound extracted from patent WO2018024188A1, Compound Example 17.4. Acid secretion-IN-1 is synthesized and used in the IDO inhibitor synthetic experiment .
    Acid secretion-IN-1
  • HY-121107R
    Chrysene (Standard)

    		Biochemical Assay Reagents Cancer
    Chrysene (Standard) is the analytical standard of Chrysene. This product is intended for research and analytical applications. Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties .
    Chrysene (Standard)
  • HY-W026772S
    Fluorene-d10

    		Fluorescent Dye Isotope-Labeled Compounds Others
    Fluorene-d10 is the deuterium labeled Fluorene. Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative can be used as a precursor to fluorene-based dyes[1].
    Fluorene-d10
  • HY-W013570S
    Acenaphthylene-d8

    Acenaphthylene-d8

    		 Isotope-Labeled Compounds Others
    Acenaphthylene-d8 is the deuterium labeled Acenaphthylene[1]. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter[2].
    Acenaphthylene-d8
  • HY-156228
    RGB-1

    		Ras Cancer
    RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells .
    RGB-1
  • HY-N12527
    Hyperelamine A

    		NF-κB Others
    Hyperelamine A (compound 5) is a polycyclic polyprenylated acylphloroglucinols (PPAPs). Hyperelamine A exhibits inhibitory activity against LPS-activated NO production in BV-2 cells via TLR-4/NF κB signaling .
    Hyperelamine A
  • HY-N0823
    Lithospermic acid

    (+)-Lithospermic acid

    		 NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis Cardiovascular Disease Inflammation/Immunology
    Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .
    Lithospermic acid
  • HY-B1727S
    Phenanthrene-d10

    		Isotope-Labeled Compounds Inflammation/Immunology
    Phenanthrene-d10 is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices[1]. Phenanthrene induces oxidative stress and inflammation[2].
    Phenanthrene-d10
  • HY-W007692R
    Acetylpyrazine (Standard)

    		Drug Intermediate Others
    Acetylpyrazine (Standard) is the analytical standard of Acetylpyrazine. This product is intended for research and analytical applications. Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
    Acetylpyrazine (Standard)
  • HY-N11222
    Nonanoylcarnitine

    C9 carnitine

    		 Endogenous Metabolite Cardiovascular Disease Cancer
    Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction .
    Nonanoylcarnitine
  • HY-W014075S
    1-Hydroxypyrene-d9

    		Endogenous Metabolite Metabolic Disease
    1-Hydroxypyrene-d9 is the deuterium labeled 1-Hydroxypyrene[1]. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes[2].
    1-Hydroxypyrene-d9
  • HY-111450
    CB7993113

    		Aryl Hydrocarbon Receptor Cancer
    CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively .
    CB7993113
  • HY-P10033
    SFTI-1

    		Ser/Thr Protease Others
    SFTI-1 is a cyclic peptide trypsin inhibitor comprising 14 amino acid residues. SFTI-1 is a potent Bowman-Birk inhibitor.
    SFTI-1
  • HY-W089800S
    trans-2-Nonenal-d2

    trans-2-Nonen-1-al-d2

    		 Biochemical Assay Reagents Isotope-Labeled Compounds Others
    trans-2-Nonenal-d2 is deuterated labeled Acetylpyrazine (HY-W007692). Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
    trans-2-Nonenal-d2
  • HY-B1727R
    Phenanthrene (Standard)

    		Apoptosis Inflammation/Immunology Cancer
    Phenanthrene (Standard) is the analytical standard of Phenanthrene. This product is intended for research and analytical applications. Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment .
    Phenanthrene (Standard)
  • HY-121014
    Amphimedine

    		Reactive Oxygen Species Cancer
    Amphimedine is a polycyclic alkaloid isolated from the marine sponge Amphimedon sp. and belongs to the pyridoindole alkaloid class. Amphimedine has cytotoxic activity and has been studied as an anticancer metabolite along with neoamphimedine. Studies have shown that deoxyamphimedine damages DNA by generating reactive oxygen species, a mechanism different from that of amphimedine.
    Amphimedine
  • HY-W127705
    Quinacrine mustard dihydrochloride

    		Fluorescent Dye Others
    Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
    Quinacrine mustard dihydrochloride
  • HY-N0823R
    Lithospermic acid (Standard)

    		NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis Cardiovascular Disease Inflammation/Immunology
    Lithospermic acid (Standard) is the analytical standard of Lithospermic acid. This product is intended for research and analytical applications. Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .
    Lithospermic acid (Standard)
  • HY-W011577
    Benzo[f]tetraphene

    Dibenz[a,c]anthracene

    		 Photosensitizer
    Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.
    Benzo[f]tetraphene
  • HY-W096906
    Naphthacene

    Benz[b]anthracene

    		 Biochemical Assay Reagents Endogenous Metabolite Others
    Naphthacene (Benz[b]anthracene) is a fused polycyclic aromatic compound exhibiting an electron field-effect mobility of approximately 10 cm2/Vs; it is an ethylnylated acene that functions as a conducting polymer, making it suitable for use as a donor material. Its exceptional photoluminescence and quantum yield position naphthacene as a highly promising candidate for the advancement of single crystal electronic materials.
    Naphthacene
  • HY-W090294
    Perylene

    Peri-dinaphthalene (purified by sublimation); Perylene

    		 Biochemical Assay Reagents Others
    Perylene, which is a polycyclic aromatic hydrocarbon composed of four linearly fused benzene rings, is commonly used as a pigment and dye in a variety of applications, including printing inks, plastics, and textiles. In addition, Perylene has potential uses in solar cells as photosensitizers and as fluorescent probes in biochemistry and materials science. Perylene's rigid planar structure endows it with unique electronic and optical properties, making it a versatile and important compound in many fields of chemistry and materials science.
    Perylene

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