2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. SIRT-IN-5

SIRT-IN-5 is a SIRT3 inhibitor, with an IC50 value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ.

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SIRT-IN-5 Chemical Structure

SIRT-IN-5 Chemical Structure

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SIRT-IN-5 Related Antibodies

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Description

SIRT-IN-5 is a SIRT3 inhibitor, with an IC50 value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ[1].
Molecular Weight

491.56

Formula

C30H26FN5O
SMILES

O=C(N1CCN(CC1)C2=CC=CC=C2F)C3=CC(C4=CC=C(C=C4)N5C=CN=C5)=NC6=CC=C(C)C=C63
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SIRT-IN-5 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SIRT-IN-5SirtuinSIRT3multiple myeloma cellCD49eInhibitorinhibitorinhibit

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