2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. Tubulin polymerization-IN-31

Tubulin polymerization-IN-31 (Compound 4c) is a tubulin polymerization inhibitor with an IC50 of 3.64 μM. Tubulin polymerization-IN-31 induces cancer cell apoptosis and shows antitumor activity.

For research use only. We do not sell to patients.

Tubulin polymerization-IN-31 Chemical Structure

Tubulin polymerization-IN-31 Chemical Structure

CAS No. : 2421121-79-9

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Tubulin polymerization-IN-31 Related Antibodies

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Description

Tubulin polymerization-IN-31 (Compound 4c) is a tubulin polymerization inhibitor with an IC50 of 3.64 μM. Tubulin polymerization-IN-31 induces cancer cell apoptosis and shows antitumor activity[1].

IC50 & Target

IC50: 3.64 μM (Tubulin polymerization)[1]
In Vitro

Tubulin polymerization-IN-31 (Compound 4c) shows antitumor activities with IC50 values of 6.02 ± 0.5, 8.45 ± 1.0 and 6.28 ± 0.6 μM against HepG2, HCT-116 and MCF-7, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tubulin polymerization-IN-31 Related Antibodies
Molecular Weight

325.77

Formula

C18H13ClFN3
CAS No.
SMILES

N#CC1=C2CCCCC2=C(C3=C(F)C=CC=C3Cl)C(C#N)=C1N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tubulin polymerization-IN-31 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-312421121-79-9Microtubule/TubulinApoptosisantitumorcaspase 3caspase 9HepG2HCT-116MCF-7Inhibitorinhibitorinhibit

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