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  6. 4'-Demethylpodophyllotoxone

4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823).

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4'-Demethylpodophyllotoxone Chemical Structure

4'-Demethylpodophyllotoxone Chemical Structure

CAS No. : 93780-84-8

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4'-Demethylpodophyllotoxone Related Antibodies

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Description

4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823)[1].

Molecular Weight

398.36

Formula

C21H18O8
CAS No.
SMILES

O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)O)C4=CC(OCO5)=C5C=C4C([C@@]2([H])CO1)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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4'-Demethylpodophyllotoxone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-Demethylpodophyllotoxone93780-84-8OthersBiotransformation product heterogeneityBiotransformation metabolic pathwayYeast extractInhibitorinhibitorinhibit

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