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  4. BYK 191023 dihydrochloride

BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS .

For research use only. We do not sell to patients.

BYK 191023 dihydrochloride Chemical Structure

BYK 191023 dihydrochloride Chemical Structure

CAS No. : 1216722-25-6

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5 mg USD 258 In-stock
10 mg USD 413 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of BYK 191023 dihydrochloride:

BYK 191023 dihydrochloride Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE BYK 191023 dihydrochloride

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Description

BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1].

Molecular Weight

327.21

Formula

C14H16Cl2N4O
CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

COC1=CC=NC(CCC2=NC3=NC=CC=C3N2)=C1.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (764.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0561 mL 15.2807 mL 30.5614 mL
5 mM 0.6112 mL 3.0561 mL 6.1123 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0561 mL 15.2807 mL 30.5614 mL 76.4035 mL
5 mM 0.6112 mL 3.0561 mL 6.1123 mL 15.2807 mL
10 mM 0.3056 mL 1.5281 mL 3.0561 mL 7.6404 mL
15 mM 0.2037 mL 1.0187 mL 2.0374 mL 5.0936 mL
20 mM 0.1528 mL 0.7640 mL 1.5281 mL 3.8202 mL
25 mM 0.1222 mL 0.6112 mL 1.2225 mL 3.0561 mL
30 mM 0.1019 mL 0.5094 mL 1.0187 mL 2.5468 mL
40 mM 0.0764 mL 0.3820 mL 0.7640 mL 1.9101 mL
50 mM 0.0611 mL 0.3056 mL 0.6112 mL 1.5281 mL
60 mM 0.0509 mL 0.2547 mL 0.5094 mL 1.2734 mL
80 mM 0.0382 mL 0.1910 mL 0.3820 mL 0.9550 mL
100 mM 0.0306 mL 0.1528 mL 0.3056 mL 0.7640 mL
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BYK 191023 dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BYK 1910231216722-25-6BYK191023BYK-191023Othersinducible nitric-oxide synthasehuman cell linesSf9 cellsInhibitorinhibitorinhibit

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