2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Creosol

Creosol  (Synonyms: 2-Methoxy-4-methylphenol)

Cat. No.: HY-W040971 Purity: 99.38%
SDS COA Handling Instructions

Molarity Calculator

Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass.

For research use only. We do not sell to patients.

Creosol Chemical Structure

Creosol Chemical Structure

CAS No. : 93-51-6

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 28 In-stock
Solution
10 mM * 1 mL in DMSO USD 28 In-stock
Liquid
500 mg USD 25 In-stock
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Creosol:

Creosol Related Antibodies

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Description

Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass[1][2][3].

In Vivo
Animal Model: New Zealand White rabbits[1]
Dosage: 100 mg/kg
Administration: daily dietary administration,
Result: Induced skeletal and external variations (o-cresol) and initial teratogenic effects (m-cresol) in rabbits.
Animal Model: Male Wistar rats[1]
Dosage: a mixture of m-cresol (160 mg/kg) and p-cresol (100 mg/kg)
Administration: a single gavage dose
Result: 50% of the administered doses of m-cresol and p-cresol were still found in the stomach after 15 minutes, while these were no longer detected after 8 hours in rats.
Molecular Weight

138.16

Formula

C8H10O2
CAS No.
Appearance

Liquid (Density: 1.092 g/cm3)

Color

Colorless to light yellow

SMILES

OC1=CC=C(C)C=C1OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (723.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2380 mL 36.1899 mL 72.3798 mL
5 mM 1.4476 mL 7.2380 mL 14.4760 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (18.09 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (18.09 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.82%

SDS (393 KB)

COA (249 KB) HNMR (119 KB) GC (75 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.2380 mL 36.1899 mL 72.3798 mL 180.9496 mL
5 mM 1.4476 mL 7.2380 mL 14.4760 mL 36.1899 mL
10 mM 0.7238 mL 3.6190 mL 7.2380 mL 18.0950 mL
15 mM 0.4825 mL 2.4127 mL 4.8253 mL 12.0633 mL
20 mM 0.3619 mL 1.8095 mL 3.6190 mL 9.0475 mL
25 mM 0.2895 mL 1.4476 mL 2.8952 mL 7.2380 mL
30 mM 0.2413 mL 1.2063 mL 2.4127 mL 6.0317 mL
40 mM 0.1809 mL 0.9047 mL 1.8095 mL 4.5237 mL
50 mM 0.1448 mL 0.7238 mL 1.4476 mL 3.6190 mL
60 mM 0.1206 mL 0.6032 mL 1.2063 mL 3.0158 mL
80 mM 0.0905 mL 0.4524 mL 0.9047 mL 2.2619 mL
100 mM 0.0724 mL 0.3619 mL 0.7238 mL 1.8095 mL
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Creosol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Creosol93-51-62-Methoxy-4-methylphenolEndogenous Metaboliteendogenous metabolitebiofuellignocellulosic biomassligninbisphenol?A replacementsInhibitorinhibitorinhibit

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