Dihydropinosylvin

Name: Dihydropinosylvin
Brand: MedChemExpress
SKU: HY-N3753
Rating: 4.5 (1 reviews)

Cat. No.: HY-N3753 Purity: 99.91%: Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

Dihydropinosylvin is a stilbenoid that can be found in Stemona collinsae.

For research use only. We do not sell to patients.

Dihydropinosylvin Chemical Structure

CAS No. : 14531-52-3

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: April 11
Solution
10 mM * 1 mL in DMSO	USD 35	In-stock	Estimated Time of Arrival: April 11
Solid
25 mg	USD 32	In-stock	Estimated Time of Arrival: April 11
50 mg	USD 50	In-stock	Estimated Time of Arrival: April 11
100 mg	USD 70	In-stock	Estimated Time of Arrival: April 11
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Dihydropinosylvin is a stilbenoid that can be found in Stemona collinsae^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BC	IC₅₀	> 93.4 μM Compound: 17	Cytotoxicity against BC cells by colorimetric method Cytotoxicity against BC cells by colorimetric method	[PMID: 17480099]
KB	IC₅₀	> 93.4 μM Compound: 17	Cytotoxicity against KB cells by colorimetric method Cytotoxicity against KB cells by colorimetric method	[PMID: 17480099]

Molecular Weight

214.26

Formula

C₁₄H₁₄O₂

CAS No.

14531-52-3

Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(CCC2=CC=CC=C2)=CC(O)=C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (466.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6672 mL	23.3361 mL	46.6723 mL
5 mM	0.9334 mL	4.6672 mL	9.3345 mL
10 mM	0.4667 mL	2.3336 mL	4.6672 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.67 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (11.67 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (11.67 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: 99.91%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (245 KB) HNMR (239 KB) LCMS (250 KB)

Handling Instructions (2659 KB)

References

[1]. Adams M, et al. Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species. J Nat Prod. 2005 Jan;68(1):83-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.6672 mL	23.3361 mL	46.6723 mL	116.6807 mL
	5 mM	0.9334 mL	4.6672 mL	9.3345 mL	23.3361 mL
	10 mM	0.4667 mL	2.3336 mL	4.6672 mL	11.6681 mL
	15 mM	0.3111 mL	1.5557 mL	3.1115 mL	7.7787 mL
	20 mM	0.2334 mL	1.1668 mL	2.3336 mL	5.8340 mL
	25 mM	0.1867 mL	0.9334 mL	1.8669 mL	4.6672 mL
	30 mM	0.1556 mL	0.7779 mL	1.5557 mL	3.8894 mL
	40 mM	0.1167 mL	0.5834 mL	1.1668 mL	2.9170 mL
	50 mM	0.0933 mL	0.4667 mL	0.9334 mL	2.3336 mL
	60 mM	0.0778 mL	0.3889 mL	0.7779 mL	1.9447 mL
	80 mM	0.0583 mL	0.2917 mL	0.5834 mL	1.4585 mL
	100 mM	0.0467 mL	0.2334 mL	0.4667 mL	1.1668 mL