Glucosylceramide (gaucher's spleen)  (Synonyms: Glucocerebrosides; Gaucher cerebroside; GluCers (gaucher's spleen))

Glucosylceramides are sphingolipid molecules found in both neuronal and non-neuronal mammalian tissues, as well as in low quantities across various plant species. Elevated levels of glucosylceramides provide cellular protection and prepare certain cells for proliferation; however, they have also been linked to obesity-induced insulin resistance in mice and to neuronal deficits observed in neuronopathic Gaucher disease^[1].

85305-87-9

Solid

White to off-white

O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O)OC[C@H](NC([R])=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)CO)O

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Holland WL, et al. Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev. 2008 Jun;29(4):381-402.  [Content Brief]