Hydroxylapatite (25-45 μm) (Synonyms: Hydroxyapatite (25-45 μm))

Cat. No.: HY-D0835 Purity: 99%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Hydroxylapatite (Hydroxyapatite) (25-45 μm) is a natural form of calcium phosphate and is the main mineral component of bones and teeth. Hydroxylapatite (25-45 μm) can stimulate the expression and secretion of collagen in primary human dermal fibroblasts. Hydroxylapatite (25-45 μm) has good biocompatibility, bioactivity, and bone conductivity, making it suitable for targeted drug or nucleic acid delivery. Hydroxylapatite (25-45 μm) can be used in research on osteoarthritis, gout, and atherosclerosis.

For research use only. We do not sell to patients.

Hydroxylapatite (25-45 μm) Chemical Structure

CAS No. : 1306-06-5

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500 mg	In-stock	Estimated Time of Arrival: December 31
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Other Forms of Hydroxylapatite (25-45 μm):

Hydroxylapatite (<50 nm) Get quote

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Description

In Vitro

Hydroxylapatite is suspended in 0.2 μm filtered purified water, sonicated and vortexed for 5 min and collected by centrifugation at 16,000 g for 1 min. The procedure was repeated five times to wash the Hydroxylapatite particles and a 40 mg/mL stock suspension was prepared in 0.1 M NaCl before administering to cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

502.31

Formula

Ca₅HO₁₃P₃

CAS No.

1306-06-5

Appearance

Solid

Color

White to off-white

SMILES

O[Ca][Ca][Ca][Ca][Ca]P1(OOO1)=O.O=P2(P3(OOO3)=O)OOO2

Structure Classification

Others

Initial Source

Animals

bones

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Ethanol : < 1 mg/mL (insoluble)

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Moumita Rakshit, et al. Hydroxyapatite Particles Induced Modulation of Collagen Expression and Secretion in Primary Human Dermal Fibroblasts. Int J Nanomedicine. 2020; 15: 4943-4956. [Content Brief]

[2]. Yongjia Liu, et al. Hydroxyapatite-Bovine Serum Albumin-Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma. Adv Healthc Mater. 2020 Nov 9;e2000573. [Content Brief]

Hydroxylapatite (25-45 μm) Related Classifications

Inflammation/Immunology Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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