2. PROTAC Apoptosis
  3. Ligands for Target Protein for PROTAC Bcl-2 Family
  4. PROTAC Bcl-xL ligand-1

PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

PROTAC Bcl-xL ligand-1 Chemical Structure

PROTAC Bcl-xL ligand-1 Chemical Structure

CAS No. : 3029365-95-2

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PROTAC Bcl-xL ligand-1 Related Antibodies

Top Publications Citing Use of Products

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim

  • Biological Activity

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  • References

  • Customer Review

Description

PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC Bcl-xL ligand-1 Related Antibodies
Molecular Weight

724.63

Formula

C32H29IN4O4S2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C(CCCOC2=CC=C(I)C=C2)SC(N3CCC4=C(C(C(NC5=NC6=CC=CC=C6S5)=O)=CC=C4)C3)=N1)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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PROTAC Bcl-xL ligand-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC Bcl-xL ligand-13029365-95-2Ligands for Target Protein for PROTACBcl-2 FamilyTarget Protein-binding MoietyBcl-xLPROTACInhibitorinhibitorinhibit

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PROTAC Bcl-xL ligand-1
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