2. Metabolic Enzyme/Protease
  3. Acyltransferase
  4. Sandoz 58-035

Sandoz 58-035 is a competitive inhibitor of cholesterol acyltransferase (ACAT). Sandoz 58-035 effectively inhibits (>98%) hormonally stimulated cholesterol esterification in cells.

For research use only. We do not sell to patients.

Sandoz 58-035 Chemical Structure

Sandoz 58-035 Chemical Structure

CAS No. : 78934-83-5

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1 mg USD 892 In-stock
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Based on 1 publication(s) in Google Scholar

Sandoz 58-035 Related Antibodies

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View All Acyltransferase Isoform Specific Products:

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ACAT1 ACAT2 MGAT2 ACAT

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Description

Sandoz 58-035 is a competitive inhibitor of cholesterol acyltransferase (ACAT). Sandoz 58-035 effectively inhibits (>98%) hormonally stimulated cholesterol esterification in cells[1].

Molecular Weight

465.79

Formula

C30H47NOSi
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC(C1=CC=CC=C1)CC2=CC=C(C)C=C2)CC[Si](C)(CCCCCCCCCC)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 16 mg/mL (34.35 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1469 mL 10.7345 mL 21.4689 mL
5 mM 0.4294 mL 2.1469 mL 4.2938 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.7%

COA (241 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1469 mL 10.7345 mL 21.4689 mL 53.6723 mL
5 mM 0.4294 mL 2.1469 mL 4.2938 mL 10.7345 mL
10 mM 0.2147 mL 1.0734 mL 2.1469 mL 5.3672 mL
15 mM 0.1431 mL 0.7156 mL 1.4313 mL 3.5782 mL
20 mM 0.1073 mL 0.5367 mL 1.0734 mL 2.6836 mL
25 mM 0.0859 mL 0.4294 mL 0.8588 mL 2.1469 mL
30 mM 0.0716 mL 0.3578 mL 0.7156 mL 1.7891 mL
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Sandoz 58-035 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sandoz 58-03578934-83-5AcyltransferaseDiacylglycerol acyltransferaseDiglyceride acyltransferaseacyl-CoA:cholesterol acyltransferasemono- acylglycerol acyltransferasecholesterol esterificationInhibitorinhibitorinhibit

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