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Results for "

(S,R,S)-AHPC-CO-C9-NH2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	E3 Ligase Ligand-Linker Conjugates (44) Ligands for E3 Ligase (5) Mixed Lineage Kinase (1) PROTAC Linkers (1) PROTACs (1)
By Research Areas:	Cancer (49) Inflammation/Immunology (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143276A

*(S,S,R)-AHPC-C6-NH2* hydrochloride**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,S,R)-AHPC-C6-NH2 hydrochloride is the hydrochloride salt form of (S,S,R)-AHPC-C6-NH2 (HY-143276). (S,S,R)-AHPC-C6-NH2 hydrochloride is the E3 ligase ligand-linker conjugate, which can be utilized for synthesis of PROTAC HL-8 (HY-143275) .

HY-139218

(S,R,S)-AHPC-Me-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Others
(S,R,S)-AHPC-Me-C6-NH2 can be used for the synthesis of PROTAC . (S,R,S)-AHPC-Me-C6-NH2 (Compound SI-9) contains VHL ligand 2 (HY-112078) .

HY-133487B

(S,R,S)-AHPC-C8-NH2 VH032-C8-NH2	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology Cancer
(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1 .

HY-130711C

*(S,R,S)-AHPC-C3-NH2* dihydrochloride** VH032-C3-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C3-NH2 (dihydrochloride) is the dihydrochloride form of (S,R,S)-AHPC-C3-NH2 (HY-130711). (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .

HY-136008A

*(S,R,S)-AHPC-PEG1-NH2* dihydrochloride** VH032-PEG1-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs .

HY-129941A

*(S,R,S)-AHPC-C10-NH2* dihydrochloride** VH032-C10-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-C10-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC .

HY-129941

(S,R,S)-AHPC-C10-NH2 VH032-C10-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC .

HY-130847

(S,R,S)-AHPC-Me-C10-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602) .

HY-103603B

*(S,R,S)-AHPC-PEG2-NH2* dihydrochloride** VH032-PEG2-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs .

HY-133487

*(S,R,S)-AHPC-C8-NH2* dihydrochloride** VH032-C8-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology Cancer
(S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1 .

HY-136006A

*(S,R,S)-AHPC-C6-NH2* hydrochloride** VH032-C6-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology Cancer
(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1 .

HY-136006

*(S,R,S)-AHPC-C6-NH2* dihydrochloride** VH032-C6-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology Cancer
(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1 .

HY-136184

*(S,R,S)-AHPC-phenol-C4-NH2* dihydrochloride** VH032-phenol-C4-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology .

HY-130711

(S,R,S)-AHPC-C3-NH2 VH032-C3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .

HY-130711A

*(S,R,S)-AHPC-C3-NH2* TFA** VH032-C3-NH2 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader .

HY-136163

*(S,R,S)-AHPC-C2-NH2* dihydrochloride**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs .

HY-130711B

*(S,R,S)-AHPC-C3-NH2* hydrochloride** VH032-C3-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology .

HY-136006B

(S,R,S)-AHPC-C6-NH2 VH032-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C6-NH2 (VH032-C6-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology .

HY-133487A

*(S,R,S)-AHPC-C8-NH2* hydrochloride** VH032-C8-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology .

HY-136008

(S,R,S)-AHPC-PEG1-NH2 VH032-PEG1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology .

HY-138861

(S,R,S)-AHPC-C1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology .

HY-138861A

*(S,R,S)-AHPC-C1-NH2* hydrochloride**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology .

HY-114176B

*(S,R,S)-AHPC-C4-NH2* dihydrochloride** VH032-C4-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC .

HY-114176A

(S,R,S)-AHPC-C4-NH2 VH032-C4-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC .

HY-136187

(S,R,S)-AHPC-C5-NH2 VH032-C5-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader .

HY-136187A

*(S,R,S)-AHPC-C5-NH2* dihydrochloride** VH032-C5-NH2 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader .

HY-130816

(S,R,S)-AHPC-O-Ph-PEG1-NH2 VH032-O-Ph-PEG1-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is E3 ligase ligand-linker conjugate and incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-O-Ph-PEG1-NH2 is used in PROTAC EED degrader-1 (HY-130614). PROTAC EED degrader-1 is a PROTAC targeting EED with a pK_D of 9.02 .

HY-136163A

(S,R,S)-AHPC-C2-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology .

HY-160555A

*(S,R,S)-AHPC-CO-C9-NH2* hydrochloride**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-CO-C9-NH2 (hydrochloride) is a von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs..

HY-160555

(S,R,S)-AHPC-CO-C9-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs.

HY-103603

*(S,R,S)-AHPC-PEG2-NH2* hydrochloride** VH032-PEG2-NH2 hydrochloride; VHL Ligand-Linker Conjugates 3 hydrochloride; E3 ligase Ligand-Linker Conjugates 6	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs .

HY-103602B

*(S,R,S)-AHPC-PEG3-NH2* dihydrochloride** VH032-PEG3-NH2 dihydrochloride; VHL Ligand-Linker Conjugates 1 dihydrochloride; E3 ligase Ligand-Linker Conjugates 5 dihydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-NH2 dihydrochloride (VH032-PEG3-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology

HY-143276

(S,S,R)-AHPC-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,S,R)-AHPC-C6-NH2 is a E3 Ligase Ligand-Linker Conjugate of HL-8 (HY-143275). HL-8 is a PROTAC molecule targeting PI3K kinase .

HY-103603A

(S,R,S)-AHPC-PEG2-NH2 VH032-PEG2-NH2 ; VHL Ligand-Linker Conjugates 3 ; E3 ligase Ligand-Linker Conjugates 6 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs .

HY-138553A

*(S,R,S)-AHPC-isobutyl acetate-methanesulfonothioate-Me-C10-NH2* TFA**	Others	Cancer
(S,R,S)-AHPC-isobutyl acetate-methanesulfonothioate-Me-C10-NH2 TFA is a part of PROTAC BRD4 Degrader-12 (HY-138635) .

HY-131387

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 can be used in PROTAC BRD4 Degrader-5 (HY-133737) and PROTAC BRD4 Degrader-5-CO-PEG3-N3 (HY-133736) .

HY-138551A

*(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-Me-C10-NH2* TFA**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-Me-C10-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC ligand, it can be used in PROTAC technology .

HY-138550A

*(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2* TFA**	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based ligand and 3-unit PEG linker used in PROTAC technology .

HY-114176

*(S,R,S)-AHPC-C4-NH2* hydrochloride** VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC .

HY-103602

*(S,R,S)-AHPC-PEG3-NH2* hydrochloride** VH032-PEG3-NH2 hydrochloride; VHL Ligand-Linker Conjugates 1 hydrochloride; E3 ligase Ligand-Linker Conjugates 5	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

HY-103604

*(S,R,S)-AHPC-PEG4-NH2* hydrochloride** 2 Publications Verification VH032-PEG4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 4 hydrochloride; E3 ligase Ligand-Linker Conjugates 7	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

HY-103602A

(S,R,S)-AHPC-PEG3-NH2 VH032-PEG3-NH2; VHL Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 5 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

HY-103604A

(S,R,S)-AHPC-PEG4-NH2 2 Publications Verification VH032-PEG4-NH2; VHL Ligand-Linker Conjugates 4 ; E3 ligase Ligand-Linker Conjugates 7 Free Base	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

HY-101763A

*(S,R,S)-AHPC* monohydrochloride** 1 Publications Verification VH032-NH2 monohydrochloride; VHL ligand 1 monohydrochloride	Ligands for E3 Ligase	Others
(S,R,S)-AHPC (VH032-NH2; VHL ligand 1) hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein .

HY-125845

(S,R,S)-AHPC 1 Publications Verification VH032-NH2; VHL ligand 1	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC₅₀ of 1.11 μM in Ba/F3 cells .

HY-101763B

*(S,R,S)-AHPC* dihydrochloride** VH032-NH2 dihydrochloride; VHL ligand 1 dihydrochloride	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC (VH032-NH2) dihydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC dihydrochloride can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC₅₀ of 1.11 μM in Ba/F3 cells .

HY-110402

*(S,R,S)-AHPC* TFA** VH032-NH2 TFA; VHL ligand 1 TFA	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC (VH032-NH2) TFA is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC₅₀ of 1.11 μM in Ba/F3 cells .

HY-169095

(S,R,S)-AHPC-Me-CO-C9-NH2	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-Me-CO-C9-NH2yes E3Ligase ligand and PROTAC LinkerThe conjugate can be used to synthesize PROTACMolecules, such as MS41 (HY-169093).

HY-168026

CEP1347-VHL-02	PROTACs Mixed Lineage Kinase	Cancer
CEP1347-VHL-02 is a PROTAC targeting MLK3. CEP1347-VHL-02 consists of PROTAC target protein ligand CEP-1347 (HY-10412) (red part), E3 ubiquitin ligase ligand (S,R,S)-AHPC-Me (HY-112078) (blue part) and PROTAC Linker Amino-PEG3-CH2COOH (HY-140189) (black part), of which the target protein ligand activity control is CEP-1347-acid (HY-168027), and the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 (HY-131387) ^{[1] ^.}

HY-125845A

*(S,S,S)-AHPC* hydrochloride** 2 Publications Verification (S,S,S)-VH032-NH2 hydrochloride	Ligands for E3 Ligase	Cancer
(S,S,S)-AHPC hydrochloride is a von Hippel-Lindau (VHL) amino building block. (S,S,S)-AHPC (Compound 27) is a ligand used as a negative control for (S,R,S)-AHPC. (S,R,S)-AHPC is the VH032-based VHL ligand used in the recruitment of the VHL protein .

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