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5-Hydroxy-L-tryptophan-4,6,7-d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Tryptophan Hydroxylase (1) 5-HT Receptor (1) Amino Acid Derivatives (4) Antibiotic (1) Biochemical Assay Reagents (2) Caspase (1) COX (2) DNA Methyltransferase (1) Drug Metabolite (12) Endogenous Metabolite (27) FLT3 (1) Fungal (3) Glucocorticoid Receptor (1) Glucosidase (1) Indoleamine 2,3-Dioxygenase (IDO) (3) Interleukin Related (1) Isotope-Labeled Compounds (33) Mitochondrial Metabolism (1) Neurokinin Receptor (1) Parasite (1) Small Interfering RNA (siRNA) (1) VD/VDR (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (3) Endocrinology (1) Infection (5) Inflammation/Immunology (6) Metabolic Disease (25) Neurological Disease (9)
Oligonucleotides:	Pre-designed siRNA Sets (1) Solubilizing Agents (1) Freeze-drying Protective Agents (1) siRNAs (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Tryptophan Hydroxylase P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W050025

6-Chloro-L-tryptophan	Amino Acid Derivatives	Others
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ .

HY-W012480S

*DL-Tryptophan-d3* (±)-tryptophan-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
DL-Tryptophan-d₃ is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.

HY-W012480S1

*DL-Tryptophan-d8* (±)-tryptophan-d<sub>8sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
DL-Tryptophan-d₈ is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.

HY-N0623S

*L-Tryptophan-d5* tryptophan-d<sub>5sub>; tryptophane-d<sub>5sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S5

*L-Tryptophan-d8* tryptophan-d<sub>8sub>; tryptophane-d<sub>8sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₈ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S9

*L-Tryptophan-d3* tryptophan-d<sub>3sub>; tryptophane-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₃ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-146628S

*5-Hydroxy-L-tryptophan-4,6,7-d3*	Isotope-Labeled Compounds	Infection
5-Hydroxy-L-tryptophan-4,6,7-d₃ is the deuterium labeled 5-Hydroxy-L-tryptophan-4,6,7[1].

HY-138815

(S)-N-(1H-Indole-3-acetyl)tryptophan	Glucosidase	Metabolic Disease
(S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase .

HY-W077257

5-Bromo-DL-tryptophan	Endogenous Metabolite	Others
5-Bromo-DL-tryptophan is a natural product which can be obtained from Aspergillus fumigatus .

HY-W008216S

HMMNI-d3 Hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Infection
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-20897A

5-Bromo-L-tryptophan	Endogenous Metabolite	Others
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp. .

HY-N0623S2

*L-Tryptophan-13C11* tryptophan-¹³C<sub>11sub>; tryptophane-¹³C<sub>11sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C₁₁ is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S8

*L-Tryptophan-15N2* tryptophan-¹⁵N<sub>2sub>; tryptophane-¹⁵N<sub>2sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S6

*L-Tryptophan-15N2,d8* tryptophan-¹⁵N<sub>2sub>,d<sub>8sub>; tryptophane-¹⁵N<sub>2sub>,d<sub>8sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S4

*L-Tryptophan-13C11,15N2* tryptophan-¹³C<sub>11sub>,¹⁵N<sub>2sub>; tryptophane-¹³C<sub>11sub>,¹⁵N<sub>2sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-W008216

HMMNI Hydroxy Dimetridazole	Drug Metabolite	Others
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .

HY-N0623R

*L-Tryptophan* (standard)** 4 Publications Verification tryptophan (standard); tryptophane (standard)	Others	Metabolic Disease
L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-W012480

DL-Tryptophan (±)-tryptophan	Endogenous Metabolite	Metabolic Disease
DL-Tryptophan is an endogenous metabolite.

HY-16724

Indoximod Maximum Cited Publications 10 Publications Verification 1-Methyl-D-tryptophan; NLG-8189	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer .

HY-W012479S

H-D-Trp-OH-d5 D-tryptophan-d<sub>5sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
H-D-Trp-OH-d₅ (D-Tryptophan-d₅) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

HY-N0623S1

*L-Tryptophan-13C* tryptophan-¹³C; tryptophane-¹³C	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S7

*L-Tryptophan-15N* tryptophan-¹⁵N; tryptophane-¹⁵N	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-W011978R

*N-Acetyl-L-tryptophan* (Standard)**	Endogenous Metabolite	Metabolic Disease
N-Acetyl-L-tryptophan (Standard) is the analytical standard of N-Acetyl-L-tryptophan. This product is intended for research and analytical applications. N-Acetyl-L-tryptophan is an endogenous metabolite.

HY-N0623S3

*L-Tryptophan-1-13C* tryptophan-1-¹³C; tryptophane-1-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan-1- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-135597

N-Acetyl-5-methyl-L-tryptophan	Others	Others
N-Acetyl-5-methyl-L-tryptophan is a N-Acetyl-L-tryptophan analog.

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-Hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-33228

5-Methyl-DL-tryptophan	Amino Acid Derivatives	Others
5-Methyl-DL-tryptophan is aamino acids and their derivatives.

HY-W142072

6-Methyl-DL-tryptophan	Biochemical Assay Reagents
6-Methyl-DL-tryptophan is a kind of biochemical reagent.

HY-W097167

N-Cbz-DL-tryptophan Z-DL-Trp-OH	Biochemical Assay Reagents	Others
N-Cbz-DL-tryptophan (Z-DL-Trp-OH) is the enantiomer of tryptophan derivative .

HY-126965

Lipid Y	Others	Others
Lipid Y is a potent monosaccharide which contains two bromines per chain. lipid Y binds to a tryptophan residue in a membrane protein and then quenches the fluorescence of the tryptophan residue .

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; Hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-Hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-W011978

N-Acetyl-L-tryptophan	Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-142127S

*2-(α-D-Mannopyranosyl)-L-tryptophan-d4*	Isotope-Labeled Compounds Antibiotic	Others
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan[1].

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6** RU 42698-d<sub>6sub>	Isotope-Labeled Compounds	Others
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111975S1

*7'-Hydroxy* ABA-d2** 7'-OH ABA-d<sub>2sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7** 7'-OH ABA-d<sub>7sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8** 8'-OH-ABA-d<sub>8sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2** 8'-OH-ABA-d<sub>2sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-128731

5-Methoxy-DL-tryptophan 1 Publications Verification DL-5-MTP	Endogenous Metabolite	Metabolic Disease
5-Methoxy-DL-tryptophan is an endogenous metabolite.

HY-N0707S

(S)-Indoximod-d3 1-Methyl-L-tryptophan-d<sub>3sub>; (S)-NLG-8189-d<sub>3sub>	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
(S)-Indoximod-d₃ is the deuterium labeled (S)-Indoximod. (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2][3].

HY-108263S

*3-Hydroxy* Midostaurin-d5** CGP52421-d<sub>5sub>	Isotope-Labeled Compounds FLT3	Cancer
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W142073

7-Methyl-DL-tryptophan 7-Methyltryptophan	Amino Acid Derivatives	Infection
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .

HY-13642

RG108 5+ Cited Publications N-Phthalyl-L-tryptophan	DNA Methyltransferase	Cancer
RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC₅₀=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences .

HY-W012479

H-D-Trp-OH D-tryptophan	Endogenous Metabolite	Metabolic Disease
H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

HY-33298

LM10	Others	Cancer
LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase (TDO). Tryptophan 2,3-dioxygenase (TDO) is an unrelated hepatic enzyme that also degrades tryptophan along the kynurenine pathway. LM10 has the potential for the research of cancer diseases .

HY-115354S

*4-Hydroxy* Alprazolam-d5** 4-Hydroxyalprazolam-d<sub>5sub>; RS-4-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W142080

α-Methyl-DL-tryptophan α-Methyltryptophan	Amino Acid Derivatives	Others
α-Methyl-DL-tryptophan (α-Methyltryptophan) is atryptophan derivative.

Cat. No.	Product Name

HY-L913

Tyrosine Focused Covalent Fragment Library

124 compounds

Recently, significant advancements in tyrosine-targeting electrophiles have primarily occurred in the field of protein-protein interactions (PPIs), where cysteine residues are often underrepresented and novel chemistries are needed to address these interfaces. In this context, tyrosines are frequently more accessible compared to more buried binding sites. Moreover, they are commonly found at "hot spots," which are functional epitopes of PPIs, with 12.3% of the residues consisting of tyrosines. This prevalence is likely due to the hydrophobic nature of tyrosine, its ability to participate in aromatic π-interactions, and its capacity for hydrogen bonding. Beyond PPIs, some progress has also been made in covalent tyrosine targeting in other areas where more commonly addressed side chains are lacking. Even though tyrosine has a slightly lower pKa value compared to the protonated lysine side chain (approximately 10 vs. 10.5 for the unprotected amino acid side chains), significantly less progress has been made in the development of tyrosine-targeted covalent ligands compared to lysine. This is likely due to the reduced flexibility of the tyrosine side chain and the greater steric hindrance of its hydroxy group, which makes it more challenging to adopt suitable reaction geometries.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 124 fragment molecules which can target tyrosine residue and can be used for fragment-based covalent drug discovery.

Cat. No.	Product Name	Target	Research Area

HY-W050025

6-Chloro-L-tryptophan	Amino Acid Derivatives	Others
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ .

HY-20897A

5-Bromo-L-tryptophan	Endogenous Metabolite	Others
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp. .

HY-33228

5-Methyl-DL-tryptophan	Amino Acid Derivatives	Others
5-Methyl-DL-tryptophan is aamino acids and their derivatives.

HY-W142080

α-Methyl-DL-tryptophan α-Methyltryptophan	Amino Acid Derivatives	Others
α-Methyl-DL-tryptophan (α-Methyltryptophan) is atryptophan derivative.

HY-138815

(S)-N-(1H-Indole-3-acetyl)tryptophan	Glucosidase	Metabolic Disease
(S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase .

HY-P4755

*N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide*	Peptides	Others
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-W142073

7-Methyl-DL-tryptophan 7-Methyltryptophan	Amino Acid Derivatives	Infection
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an amino acid derivative, which is a key precursor for biosynthesis of many non-ribosomal peptide antibiotics. 7-Methyl-DL-tryptophan plays an important role in synthesis of high-efficiency antibacterial agents and analogues thereof .

HY-158104

LPPM-8	Peptides	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-20897A

5-Bromo-L-tryptophan	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp. .

HY-N0623

L-Tryptophan 4 Publications Verification tryptophan; tryptophane	Structural Classification Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Cancer	Others
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-N0623R

*L-Tryptophan* (standard)** 4 Publications Verification tryptophan (standard); tryptophane (standard)	Structural Classification Alkaloids Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-W012480

DL-Tryptophan (±)-tryptophan	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Tryptophan is an endogenous metabolite.

HY-W011978

N-Acetyl-L-tryptophan	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-128731

5-Methoxy-DL-tryptophan 1 Publications Verification DL-5-MTP	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Methoxy-DL-tryptophan is an endogenous metabolite.

HY-W012479

H-D-Trp-OH D-tryptophan	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

HY-N12125

Entadamide A	Structural Classification Natural Products Petasites formosanus Kitam. Leguminosae Source classification Plants	Others
Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

HY-W077257

5-Bromo-DL-tryptophan	Structural Classification Alkaloids Animals Source classification Indole Alkaloids	Endogenous Metabolite
5-Bromo-DL-tryptophan is a natural product which can be obtained from Aspergillus fumigatus .

HY-W011978R

*N-Acetyl-L-tryptophan* (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
N-Acetyl-L-tryptophan (Standard) is the analytical standard of N-Acetyl-L-tryptophan. This product is intended for research and analytical applications. N-Acetyl-L-tryptophan is an endogenous metabolite.

HY-N10270

Verrucofortine	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Verrucofortine, a fungal metabolite, is an alkaloid derived from tryptophan and leucine .

HY-N0707

(S)-Indoximod 1-Methyl-L-tryptophan; (S)-NLG-8189	Structural Classification Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Source classification Abrus precatorius Linn. Plants Disease Research Fields Cancer	Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) (K_i: 19 μM). (S)-Indoximod can be used for the research of cancer and neurological disease .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

HY-59208

4-Quinolinol Kynurine	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Quinoline Alkaloids Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune .

HY-N9241

*3-Hydroxy-7-methoxyflavone*	Structural Classification Flavonols Flavonoids Labiatae Source classification Gymnaster koraiensis Plants	Others
3-Hydroxy-7-methoxyflavone (compound 1) is a flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect .

HY-N9224

*5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran*	Structural Classification Monophenols Source classification Artemisia dracunculus L. Phenols Plants Compositae	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-116688

*2-Hydroxy-4-(methylthio)butyric acid*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-N2674

*5-Hydroxy-1-methoxyxanthone* 5-Hydroxy-1-methoxyxanthen-9-one	Structural Classification Flavonoids Hypericum brasiliense Choisy Source classification Hypericaceae Plants Other Flavonoids	Others
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .

HY-135212R

Hydroxy ipronidazole (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-126121R

*2-Hydroxy* Ibuprofen (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	COX
2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

Species:	Human (19) E.coli (3)
Tag:	GFP (3) His (20) Tag Free (1) Strep (5) Myc (1) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli Cell-free (1) Sf9 insect cells (1) E. coli (10)

Cat. No.	Compare	Product Name	Species	Source

HY-P71098

	Tryptophan Synthase Protein, E.coli (His) tryptophan synthetase; tryptophan synthase	E.coli	E. coli
	The TrpA protein, especially its α subunit, plays a crucial role in catalyzing the aldol cleavage of indole glycerol phosphate to produce indole and glyceraldehyde 3-phosphate. This enzymatic activity highlights the importance of TrpA in the tryptophan biosynthetic pathway, providing an essential component of cellular processes. Tryptophan Synthase Protein, E.coli (His) is a recombinant protein dimer complex containing E. coli-derived Tryptophan Synthase protein, expressed by E. coli , with N-6*His labeled tag. Tryptophan Synthase Protein, E.coli (His), has molecular weight of 28 & 40-50 kDa, respectively.

HY-P73566

	Tryptophan Hydroxylase 1/TPH-1 Protein, Human (His) TPH; TPH-1; TPRH; tryptophan 5-Hydroxylase 1; tryptophan Hydroxylase 1	Human	E. coli
	The tryptophan hydroxylase 1 (TPH-1) protein is key to serotonin biosynthesis, catalyzing the rate-limiting step: the oxidation of L-tryptophan to 5-hydroxy-L-tryptophan. This enzyme activity is critical for the synthesis of serotonin, a neurotransmitter that affects mood, sleep, and appetite. Tryptophan Hydroxylase 1/TPH-1 Protein, Human (His) is the recombinant human-derived Tryptophan Hydroxylase 1/TPH-1 protein, expressed by E. coli , with N-His labeled tag. The total length of Tryptophan Hydroxylase 1/TPH-1 Protein, Human (His) is 443 a.a., with molecular weight of ~48 kDa.

HY-P71097

	TrpA Protein, E.coli tryptophan synthase alpha chain; trpA;	E.coli	E. coli
	The TrpA protein, especially its α subunit, plays a crucial role in catalyzing the aldol cleavage of indole glycerol phosphate to produce indole and glyceraldehyde 3-phosphate. This enzymatic activity highlights the importance of TrpA in the tryptophan biosynthetic pathway, providing an essential component of cellular processes. TrpA Protein, E.coli is the recombinant E. coli-derived TrpA protein, expressed by E. coli , with tag free. The total length of TrpA Protein, E.coli is 268 a.a., with molecular weight of ~26 kDa.

HY-P73540

	WARS Protein, Human (sf9, His) tryptophan--tRNA ligase, cytoplasmic; IFP53; TrpRS; WARS1; WARS	Human	Sf9 insect cells
	WARS includes isomer 1, isomer 2, T1-TrpRS and T2-TrpRS, and has aminoacylation activity, except T2-TrpRS. Unlike isoform 1, isoform 2, T1-TrpRS and T2-TrpRS, exhibit vasostatic activity. WARS Protein, Human (sf9, His) is the recombinant human-derived WARS protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of WARS Protein, Human (sf9, His) is 470 a.a., with molecular weight of ~55 kDa.

HY-P72228

	HMGCR Protein, Human (His) 3 Hydroxy 3 methylglutaryl CoA reductase; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase; 3 Hydroxymethylglutaryl CoA reductase; 3-Hydroxy-3-methylglutaryl CoA reductase NADPH; ; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase; 3H3M; HMDH_HUMAN; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; Hmgcr; Hydroxymethylglutaryl CoA reductase; LDLCQ3; MGC103269; Red	Human	E. coli
	As a key enzyme in cholesterol biosynthesis, HMGCR protein plays a central role in regulating cellular cholesterol levels. It catalyzes the conversion of HMG-CoA to mevalonate, a key step in the synthesis of cholesterol and other isoprenoids. HMGCR Protein, Human (His) is the recombinant human-derived HMGCR protein, expressed by E. coli , with N-6*His labeled tag.

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P71375

	TPH2 Protein, Human (His) tryptophan 5-Hydroxylase 2; Neuronal tryptophan Hydroxylase; tryptophan 5-Monooxygenase 2; TPH2; NTPH	Human	E. coli
	TPH2 Protein, an isozyme of tryptophan hydroxylase, is a member of the pterin-dependent aromatic acid hydroxylase family. TPH2 is selectively expressed only in the serotonergic neurons of the raphe nuclei and is a rate-limiting enzyme in the brain serotonin synthesis pathway. TPH2 plays a more prominent role in the 5-HT synthesis in the brain. Moreover, it is a key factor in maintaining normal serotonin transfer in the central nervous system. TPH2 Protein, Human (His) is the recombinant human-derived TPH2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71099

	TrpB Protein, E.coli (His) tryptophan synthase beta chain; trpB	E.coli	E. coli
	The TrpB protein, especially its β subunit, plays a crucial role in the synthesis of L-tryptophan from indole and L-serine. This enzyme function involves converting precursor molecules into the essential amino acid L-tryptophan, thereby facilitating its biosynthetic pathway. TrpB Protein, E.coli (His) is the recombinant E. coli-derived TrpB protein, expressed by E. coli , with N-6*His labeled tag. The total length of TrpB Protein, E.coli (His) is 396 a.a., with molecular weight of 40-50 kDa.

HY-P702207

	ADTRP Protein, Human (Cell-Free, His, Myc) Androgen-dependent TFPI-regulating protein; Fatty acid esters of Hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP; C6orf105	Human	E. coli Cell-free
	ADTRP protein exhibits specialized enzymatic activity, specifically hydrolyzing bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), with a notable preference for branched FAHFAs. This unique function distinguishes ADTRP, as it does not hydrolyze other major lipid classes. Moreover, ADTRP regulates endothelial cells, influencing TFPI expression and cell-associated anticoagulant activity, observed in in vitro settings. ADTRP Protein, Human (Cell-Free, His, Myc) is the recombinant human-derived ADTRP protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of ADTRP Protein, Human (Cell-Free, His, Myc) is 230 a.a., with molecular weight of 31.8 kDa.

HY-P71203

	PHS Protein, Human (His) Pterin-4-Alpha-Carbinolamine Dehydratase; PHS; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha; DCoH; Dimerization Cofactor of HNF1; Phenylalanine Hydroxylase-Stimulating Protein; Pterin Carbinolamine Dehy	Human	E. coli
	PHS protein is crucial in tetrahydrobiopterin biosynthesis and has the dual function of hindering the formation of 7-pterin and promoting quinone-BH2. It also acts as a coactivator of HNF1A-dependent transcription, affecting HNF1A dimerization and enhancing its activity. PHS Protein, Human (His) is the recombinant human-derived PHS protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703334

	ABCF3 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human	Human	HEK293
	ABCF3 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCF3, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCF3 Protein, Human (HEK293, His, Strep, Flag) is 708 a.a.,

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P703309

	ABCA6 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family A member 6; ABCA6; Homo sapiens; Human; Translocase	Human	HEK293
	ABCA6 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCA6, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCA6 Protein, Human (HEK293, His, Strep, Flag) is 1616 a.a.,

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Human (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q, , , , mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P703304

	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703305

	ABCB10 Protein, Human (HEK293, Flag, His, N229A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703306

	ABCB10 Protein, Human (HEK293, Flag, His, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703307

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703308

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-W012480S

*DL-Tryptophan-d3*
DL-Tryptophan-d₃ is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.

HY-W012480S1

*DL-Tryptophan-d8*
DL-Tryptophan-d₈ is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.

HY-N0623S

*L-Tryptophan-d5*
L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S5

*L-Tryptophan-d8*
L-Tryptophan-d₈ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S9

*L-Tryptophan-d3*
L-Tryptophan-d₃ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S2

*L-Tryptophan-13C11*
L-Tryptophan- ¹³C₁₁ is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-146628S

*5-Hydroxy-L-tryptophan-4,6,7-d3*
5-Hydroxy-L-tryptophan-4,6,7-d₃ is the deuterium labeled 5-Hydroxy-L-tryptophan-4,6,7[1].

HY-W008216S

HMMNI-d3
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-N0623S8

*L-Tryptophan-15N2*
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S6

*L-Tryptophan-15N2,d8*
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S4

*L-Tryptophan-13C11,15N2*
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-W012479S

H-D-Trp-OH-d5
H-D-Trp-OH-d₅ (D-Tryptophan-d₅) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

HY-N0623S1

*L-Tryptophan-13C*
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S7

*L-Tryptophan-15N*
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S3

*L-Tryptophan-1-13C*
L-Tryptophan-1- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-142127S

*2-(α-D-Mannopyranosyl)-L-tryptophan-d4*
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan[1].

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6**
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-N0707S

(S)-Indoximod-d3
(S)-Indoximod-d₃ is the deuterium labeled (S)-Indoximod. (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2][3].

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-113294S

3-Hydroxykynurenine-13C3,15N
3-Hydroxykynurenine- ¹³C₃, ¹⁵N (3-Hydroxy-DL-kynurenine- ¹³C₃, ¹⁵N)is the ¹³C and ¹⁵N labeled3-Hydroxykynurenine(HY-113294) . 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-W021008S

*3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d2*
3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d₂ is deuterated labeled 4-Ethyl-2-methoxyphenol.

HY-12772S1

*(2R,4S)-Hydroxy* Itraconazole-d8**
(2R,4S)-Hydroxy Itraconazole-d₈ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole[1].

HY-12772S2

*(2R,4S)-Hydroxy* Itraconazole-d5**
(2R,4S)-Hydroxy Itraconazole-d₅ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole[1].

HY-124245S2

*3-Hydroxy* desloratadine-d6**
3-Hydroxy desloratadine-d₆ is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine .

HY-135335S

*3'-Hydroxy* Repaglinide-d5**
3'-Hydroxy Repaglinide-d₅ is the deuterium labeled 3'-Hydroxy Repaglinide. 3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide[1].

HY-143976S

*3-Hydroxy* imiquimod-d4**
3-Hydroxy imiquimod-d₄ is the deuterium labeled 3-Hydroxy imiquimod.

HY-143367S

*27-Hydroxy* cholesterol-d6**
27-Hydroxy cholesterol-d₆ is deuterium labeled 27-Hydroxy cholesterol.

HY-144950S

*3-Hydroxy* benzopyrene-d11**
3-Hydroxy benzopyrene-d₁₁is the deuterium labeled3-Hydroxy benzopyrene(HY-144950) . 3-Hydroxy benzopyrene is a metabolite of Benzopyrene (HY-107377) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81208

	4 Hydroxynonenal Antibody 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; HNE; 4HNE; 4-HNE; (E)-4-Hydroxy-2-nonenal; 2-Nonenal, 4-Hydroxy-, (2E)-; (2E)-4-Hydroxy-2-nonenal; 4-Hydroxy-2(E)-nonenal	WB, ELISA, IHC-P, ICC/IF	Species independent
	4 Hydroxynonenal Antibody is an unconjugated, approximately 0.156 kDa, rabbit-derived, anti-4 Hydroxynonenal polyclonal antibody. 4 Hydroxynonenal Antibody can be used for: WB, ELISA, IHC-P, IF expriments in background without labeling.

HY-P80525

	14-3-3 eta Antibody (YA838) 14-3-3 protein eta; 1433F_HUMAN; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide; YWHA 1; YWHA1; Ywhah.	WB	Human, Mouse, Rat
	14-3-3 eta Antibody (YA838) is a non-conjugated and Mouse origined monoclonal antibody about 28 kDa, targeting to 14-3-3 eta (5F2). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80527

	ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
	ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P81140

	8-OHdG (DNA/RNA Damage) Antibody 8-Hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7,8-Dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG; 2'-Deoxy-8-Hydroxyguanosine;	ELISA, IHC-P, IHC-F, ICC/IF	Human
	8-OHdG (DNA/RNA Damage) Antibody is an unconjugated, approximately 0.283 kDa, rabbit-derived, anti-8-OHdG (DNA/RNA Damage) polyclonal antibody. 8-OHdG (DNA/RNA Damage) Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, background without labeling.

HY-P81196

	HSD3B1 Antibody 3BHS1_HUMAN; 3 beta-Hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-Hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-Hydroxy-5-ene steroid dehydrogenase 1; 3-beta-Hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-Hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A	WB, ICC/IF	Human
	HSD3B1 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-HSD3B1 monoclonal antibody. HSD3B1 Antibody can be used for: WB,ICC/IF expriments in human background without labeling.

HY-P80772

	P Glycoprotein Antibody p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P83004

	Tryptophan 5 Hydroxylase 1 Antibody (YA2749) TPH1; MGC119994; TPRH; TRPH; tryptophan 5-Hydroxylase 1; tryptophan Hydroxylase	WB, IHC-P, IP	Human, Mouse, Rat
	Tryptophan 5 Hydroxylase 1 Antibody (YA2749) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2749), targeting Tryptophan 5 Hydroxylase 1, with a predicted molecular weight of 51 kDa (observed band size: 51 kDa). Tryptophan 5 Hydroxylase 1 Antibody (YA2749) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P81863

	Tryptophan tRNA Ligase Antibody (YA1608) Gamma2; hWRS; IFI53; IFP53; TrpRS; WARS; WRS	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	Tryptophan tRNA Ligase Antibody (YA1608) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1608), targeting Tryptophan tRNA Ligase, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). Tryptophan tRNA Ligase Antibody (YA1608) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P81197

	HMGCR Antibody 3 Hydroxy 3 methylglutaryl CoA reductase antibody; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 Hydroxymethylglutaryl CoA reductase antibody; 3-Hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody	WB, IP	Human, Mouse
	HMGCR Antibody is an unconjugated, approximately 97 kDa, rabbit-derived, anti-HMGCR monoclonal antibody. HMGCR Antibody can be used for: WB,IP expriments in human, mouse background without labeling.

HY-P83598

	ERAB Antibody (YA3343) HSD17B10; ERAB; HADH2; MRPP2; SCHAD; XH98G2; 3-Hydroxyacyl-CoA dehydrogenase type-2; 17-beta-Hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-Hydroxyacyl-CoA dehydrogenase type II; Endoplasmic	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	ERAB Antibody (YA3343) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3343), targeting ERAB, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). ERAB Antibody (YA3343) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P81118

	MRP2 Antibody ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; Canalicular multidrug resistance protein antibody; Canalicular multispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_HUMAN antibody; Multidrug resistance associated protein 2 antibody; Multidrug resistance-associated protein 2 antibody;	WB, ICC/IF, FC	Human
	MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.

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Cat. No.	Product Name		Classification

HY-N0623

L-Tryptophan 4 Publications Verification tryptophan; tryptophane		Freeze-drying Protective Agents Solubilizing Agents
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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5-Hydroxy-L-tryptophan-4,6,7-d<sub>3</sub>

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