Search Result
Results for "
Anthraquinones
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0571
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- HY-129042
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- HY-N0354R
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Virus Protease
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Others
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Anthraquinone (Standard) is the analytical standard of Anthraquinone. This product is intended for research and analytical applications. Anthraquinone is used as a precursor for dye formation.
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- HY-117732
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- HY-N12009
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Others
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Others
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1-Desmethylobtusin is an anthraquinone compound can be isolated from Cassia obtusifolia L .
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- HY-N10369
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Others
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Others
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1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone is an anthraquinone compound isolated from the seeds of Cassia obtusifolia .
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- HY-D0479
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- HY-N7894
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Others
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Others
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3-Hydroxymorindone is an anthraquinone and a pigment .
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- HY-N7991
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- HY-W103170
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Bacterial
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Others
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1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .
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- HY-N10371
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Others
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Others
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Physcion-8-O-β-gentiobioside is an anthraquinone glycoside isolated from rhubarb roots .
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- HY-133860
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Others
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Others
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Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation .
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- HY-N0571R
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Fungal
Bacterial
Antibiotic
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Infection
Neurological Disease
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Purpurin (Standard) is the analytical standard of Purpurin. This product is intended for research and analytical applications. Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .
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- HY-N10939
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- HY-N12006
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Glucosidase
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Others
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6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC50:185 μM), which can be isolated from Cassia seeds .
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- HY-N8022
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Lucidin 3-O-β-primeveroside
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Biochemical Assay Reagents
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Cancer
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Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts .
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- HY-130049
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Bacterial
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Infection
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Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria .
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- HY-N0312
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Phosphatase
Bacterial
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Infection
Metabolic Disease
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Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC50 of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects .
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- HY-N7599
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Phosphatase
Glucosidase
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Metabolic Disease
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Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC50s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research .
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- HY-D0943
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Kernechtrot
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Fluorescent Dye
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Others
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Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium . Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine .
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- HY-N0354S
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Virus Protease
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Others
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Anthraquinone-d8 is the deuterium labeled Anthraquinone[1]. Anthraquinone is used as a precursor for dye formation.
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- HY-N10322
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Drug Metabolite
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Others
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2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .
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- HY-B1975
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Fungal
Reactive Oxygen Species
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Infection
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Dithianon is a broad-spectrum anthraquinone fungicide with good adherence to the surface of leaves and fruits. Dithianon is used to control several several fungal of some fruits and vegetables, as anthracnose (Colletotrichum sp., Elsinoe ampelina), mildew (Plasmopara viticola), phomopsis (Phomopsis viticola), among others .
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- HY-W077242
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DNA/RNA Synthesis
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Cancer
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1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia .
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- HY-B1975R
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Fungal
Reactive Oxygen Species
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Infection
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Dithianon (Standard) is the analytical standard of Dithianon. This product is intended for research and analytical applications. Dithianon is a broad-spectrum anthraquinone fungicide with good adherence to the surface of leaves and fruits. Dithianon is used to control several several fungal of some fruits and vegetables, as anthracnose (Colletotrichum sp., Elsinoe ampelina), mildew (Plasmopara viticola), phomopsis (Phomopsis viticola), among others .
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- HY-W031757
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Others
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Inflammation/Immunology
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Anthraquinone-2-carboxylic acid is a major anthraquinone isolated from Brazilian taheebo, with anti-inflammatory activity and antinociceptive .
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- HY-N0283
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Diacerhein; Diacetylrhein
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Interleukin Related
Calcium Channel
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Inflammation/Immunology
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Diacerein (Diacerhein), an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling. Diacerein is an anti-inflammatory and anti-rheumatic drug. Diacerein can relieve bronchospasm and control airway inflammation in asthmatic mice. Diacerein has the potential for slow acting drug in osteoarthritis (SYSADOA) research .
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- HY-N0990
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Others
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Cancer
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1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC50 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay .
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- HY-N8100
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Others
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Others
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2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone 3-O-α-rhamnosyl-(1→2)-β-glucoside is anthraquinone glycoside found in the dried roots of Rubia cordifolia .
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- HY-N0354
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Virus Protease
Topoisomerase
Apoptosis
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Infection
Metabolic Disease
Inflammation/Immunology
Cancer
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Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis .
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- HY-N4153
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Others
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Others
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1-Methyl-2, 8-dihydroxy3-carboxy-9, 10-anthraquinone (compound 2) is compound isolated from the roots of Rheum palmatum .
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- HY-N8725
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Others
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Others
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(2-Methylbutyryl)shikonin is a Anthraquinone product .
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- HY-N7975
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- HY-N0105
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- HY-N8143
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- HY-N1138
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Others
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Others
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Torososide A is a Anthraquinones product that can be isolated from the leaves of Cassia torosa .
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- HY-N0886
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Aloin B
2 Publications Verification
Aloin-B; Isobarbaloin
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Others
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Others
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Aloin B is one isomer of Aloin; Aloin is a physiologically active anthraquinone present in aloe.
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- HY-N1972
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Others
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Others
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Sennoside C is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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- HY-N1973
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- HY-N7618
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Chrysophanol 8-methyl ether
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Others
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Others
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8-Methyl Chrysophanol is an anthraquinone isolated from the bark of Senna macranth .
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- HY-N3898
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Others
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Others
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Floribundone 1 is a Anthraquinones product that can be isolated from the herbs of Senna septemtrionalis .
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- HY-N8093
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Others
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Others
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2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside is a natural product that can be isolated from the roots of Rubia cordifolia .
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- HY-N8252
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Antibiotic
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Infection
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Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .
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- HY-D0288
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Fluorescent Dye
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Disperse red 86 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D1128
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Fluorescent Dye
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Disperse red 151 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D1037
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Fluorescent Dye
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Disperse red 50 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0687
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Fluorescent Dye
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Disperse red 324 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0673
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Fluorescent Dye
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Disperse red 311 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0625
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Fluorescent Dye
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Disperse Red 177 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0594
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Fluorescent Dye
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Disperse Red 278 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0545
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Fluorescent Dye
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Others
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Disperse red 91 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0515
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Fluorescent Dye
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Disperse red 73 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0513
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Fluorescent Dye
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Disperse red 65 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0393
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Fluorescent Dye
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Disperse red 54 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0349
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Fluorescent Dye
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Disperse Red 13 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0347
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Fluorescent Dye
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Disperse Red 17 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0341
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Solvent Violet 26
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Fluorescent Dye
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Disperse Red 11 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-D0315
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Fluorescent Dye
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Disperse red 74 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-N0444
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- HY-N1336
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Others
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Others
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Rubianthraquinone is a anthraquinone, that can be isolated from the roots of Rubia yunnanensis. Rubianthraquinone inhibits NO production and degranulation .
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- HY-D0316
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DR 167:1
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Fluorescent Dye
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Disperse red 167:1 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-N2714
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Others
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Inflammation/Immunology
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6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases .
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- HY-D0331
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Fluorescent Dye
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Others
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Reactive Blue 19 is an anthraquinone dye used in the textile industry as a starting material to produce polymeric dye .
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- HY-N9069
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Others
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Others
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1-O-Methylnataloe-emodin is a Anthraquinones product that can be isolated from the herbs of Aloe vera .
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- HY-N8962
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Others
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Others
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Physcion 8-O-rutinoside is a Anthraquinones product that can be isolated from the barks of Rhamnus libanoticus. .
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- HY-126708
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ADC Cytotoxin
Antibiotic
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Infection
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Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog .
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- HY-N10833
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Others
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Others
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2-Hydroxy-1,3,4-trimethoxyanthraquinone is a anthraquinone that can be found in Cinchona ledgeriana .
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- HY-N11894
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Others
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Others
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1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside ( Compound 20) is a quinone compound that can be isolated from the roots and rhizomes of Madder .
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- HY-B0738
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- HY-N0311
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Others
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Cancer
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Emodin-8-glucoside is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA .
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- HY-W353602
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Others
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Others
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Aleoe-emodin triacetate is an Anthraquinone (HY-N0354) derivative, and can be isolated from leaves of Kniphofia foliosa .
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- HY-N7619
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Purpuroxanthin
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MMP
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Metabolic Disease
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Xanthopurpurin, an anthraquinone glycoside, isolated from the roots of Rubia akane, shows mainly strong inhibition of collagen-induced platelet aggregation .
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- HY-117860
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Fluorescent Dye
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Others
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Vat Yellow 4 is a synthetic anthraquinone vat dye. Vat Yellow 4 can be used for the dyeing of cotton, rayon, and wool by textile industries .
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- HY-N9961
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Others
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Others
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2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .
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- HY-N6082
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Rhein 8-O-β-D-Glucopyranoside
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Others
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Metabolic Disease
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Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside) is an anthraquinone glycoside that has been found in rhubarb. Purgative activity .
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- HY-N0495
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Aloenin A
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Beta-secretase
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Neurological Disease
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Aloenin (Aloenin A) is a kind of natural product, has effective clearing and free radical activity, and has moderate inhibitory activity on β-secretion (BACE) (IC50=14.95 μg/mL). Aloenin suppresses peritoneal hypertrophy in large rats and suppresses its release.
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- HY-N0495R
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Beta-secretase
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Neurological Disease
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Aloenin (Standard) is the analytical standard of Aloenin. This product is intended for research and analytical applications. Aloenin (Aloenin A) is a kind of natural product, has effective clearing and free radical activity, and has moderate inhibitory activity on β-secretion (BACE) (IC50=14.95 μg/mL). Aloenin suppresses peritoneal hypertrophy in large rats and suppresses its release .
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- HY-W007618
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Biochemical Assay Reagents
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Others
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Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
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- HY-119739
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GCGR
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Metabolic Disease
Cancer
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Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells .
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- HY-N0886R
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Others
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Others
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Aloin B (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an isomer of aloin, a physiologically active anthraquinone compound in aloe.
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- HY-135770
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Others
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Cancer
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9-Dehydroxyeurotinone is an anthraquinone derivative that can be found in Eurotium rubrum. 9-Dehydroxyeurotinone shows cytotoxicity with an IC50 value of 25 µg/mL for SW1990 cells .
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- HY-13595
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Chrysophanic acid
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EGFR
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Cancer
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Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
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- HY-126597
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Bacterial
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Infection
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Chaetoglobosin C (Compound 4) is a anthraquinone-chromone compound derived from the fungus Chaetomium globosum KMITL-N0802. Chaetoglobosin C has anti-tuberculosis activity .
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- HY-N0444R
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Others
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Inflammation/Immunology
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Rubiadin (Standard) is the analytical standard of Rubiadin. This product is intended for research and analytical applications. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity .
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- HY-N1972R
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Others
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Others
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Sennoside C (Standard) is the analytical standard of Sennoside C. This product is intended for research and analytical applications. Sennoside C is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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- HY-N1973R
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Others
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Infection
Inflammation/Immunology
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Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .
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- HY-N9362
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Antibiotic
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Infection
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Emodinanthrone, an anthraquinone, is a sprecursor of Emodin (HY-14393) with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli .
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- HY-N8113
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Others
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Others
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3-(β-D-Glucopyranosyloxy)-1,6-dihydroxy-2-methyl-9,10-anthracenedione is a anthraquinone isolated from Rubia cordifolia .
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- HY-N0283R
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Diacerhein(Standard); Diacetylrhein (Standard)
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Interleukin Related
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Inflammation/Immunology
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Diacerein (Standard) is the analytical standard of Diacerein. This product is intended for research and analytical applications. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
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- HY-B0738R
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DNA/RNA Synthesis
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Inflammation/Immunology
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Dithranol (Standard) is the analytical standard of Dithranol. This product is intended for research and analytical applications. Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair .
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- HY-D0347R
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Fluorescent Dye
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Others
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Disperse Red 17 (Standard) is the analytical standard of Disperse Red 17. This product is intended for research and analytical applications. Disperse Red 17 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
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- HY-N0283S
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Diacerhein-d6; Diacetylrhein-d6
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Interleukin Related
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Inflammation/Immunology
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Diacerein-d6 is the deuterium labeled Diacerein[1]. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases[2].
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- HY-125815
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Fluorescent Dye
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Others
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Reactive Blue 4 is an anthraquinone dye, as a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media. Reactive Blue 4 is phytotoxic, cytotoxic and genotoxic. Reactive Blue 4 .
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- HY-N0365R
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HIV
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Infection
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Sennoside A (Standard) is the analytical standard of Sennoside A. This product is intended for research and analytical applications. Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia) . Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication .
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- HY-N7502
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Others
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Others
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2-(Hydroxymethyl)anthraquinone is used as a photoremovable protecting group (PRPG) to chemically cage sex pheromone (e.g. (Z)-11-hexadecen-1-ol (sex pheromone of Chilo infuscatellussnellen)) .
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- HY-N10648
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Phosphatase
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Metabolic Disease
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PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.05 μM) over the highly homologous T-cell protein tyrosine phosphatase (TCPTP; IC50=78.0 μM), which is a key target for type 2 diabetes inhibition .
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- HY-N10649
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Phosphatase
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Metabolic Disease
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PTP1B-IN-21 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 μM) over the highly homologous T-cell protein tyrosine phosphatase (TCPTP; IC50>100 μM), which is a key target for type 2 diabetes inhibition .
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- HY-N5091
-
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Others
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Inflammation/Immunology
Cancer
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Physcion 8-O-β-D-glucopyranosideis an anthraquinone compound isolated from Rumex japonicus Houtt. Physcion 8-O-β-D-glucopyranoside exerts anti-inflammatory and anti-cancer properties, can be for common malignancy cancer research .
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- HY-13595R
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Chrysophanic acid (Standard)
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EGFR
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Cancer
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Chrysophanol (Standard) is the analytical standard of Chrysophanol. This product is intended for research and analytical applications. Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
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- HY-N7598
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Monoamine Oxidase
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Neurological Disease
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Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside isolated from Cassia obtusifolia seeds. Chrysophanol-1-O-β-gentiobioside shows selective inhibition of hMAO-A isozyme activity (IC50=96.15 μM) .
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- HY-N0311R
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Others
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Cancer
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Emodin-8-glucoside (Standard) is the analytical standard of Emodin-8-glucoside. This product is intended for research and analytical applications. Emodin-8-glucoside is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA .
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- HY-N1956
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NF-κB
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Metabolic Disease
|
Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65 .
|
-
- HY-N6082R
-
|
Others
|
Metabolic Disease
|
Rhein 8-Glucoside (Standard) is the analytical standard of Rhein 8-Glucoside. This product is intended for research and analytical applications. Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside) is an anthraquinone glycoside that has been found in rhubarb. Purgative activity .
|
-
- HY-N6013
-
|
MMP
Bacterial
Fungal
|
Infection
Inflammation/Immunology
Cancer
|
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .
|
-
- HY-N9953
-
|
Others
|
Inflammation/Immunology
|
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O2 - scavenging activity .
|
-
- HY-N0261
-
|
TNF Receptor
COX
|
Cardiovascular Disease
Inflammation/Immunology
|
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .
|
-
- HY-117840
-
|
Antibiotic
Bacterial
|
Infection
|
Altromycin F is an anthraquinone-derived antibiotic produced by the actinomycete AB 1246E-26 isolated from a South African bush soil. Altromycin F has antibacterial activity against Gram-positive bacteria, particularly Streptococcus and Staphylococcus, with a microbial inhibitory concentration (MIC) ranging from 0.2-3.12 μg/mL .
|
-
- HY-135954A
-
|
PDHK
Apoptosis
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity .
|
-
- HY-135954
-
|
PDHK
Apoptosis
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 has antidiabetic, anticancer and anti-allergic activity .
|
-
- HY-N0366R
-
|
PDGFR
|
Cancer
|
Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia) . Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway .
|
-
- HY-146497
-
|
Topoisomerase
|
Cancer
|
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .
|
-
- HY-134000
-
NSC624610
|
p38 MAPK
NF-κB
ERK
JNK
VEGFR
MMP
|
Cancer
|
Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells .
|
-
- HY-N0108R
-
|
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
Physcion (Standard) is the analytical standard of Physcion. This product is intended for research and analytical applications. Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively . Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .
|
-
- HY-N0365
-
|
HIV
|
Infection
|
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
|
-
- HY-N0261R
-
|
TNF Receptor
COX
|
Cardiovascular Disease
Inflammation/Immunology
|
Aurantio-obtusin (Standard) is the analytical standard of Aurantio-obtusin. This product is intended for research and analytical applications. Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy-and AMPK/TFEB mediated inhibition of lipid accumulation .
|
-
- HY-N0108
-
Parietin; Rheochrysidin
|
Bacterial
Toll-like Receptor (TLR)
NF-κB
Apoptosis
Autophagy
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
|
-
- HY-120601
-
ARS sodium
|
Others
|
Others
|
Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm .
|
-
- HY-108485
-
|
Src
Apoptosis
Fungal
|
Infection
Inflammation/Immunology
Cancer
|
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against Candida albicans .
|
-
- HY-14393
-
Emodin
Maximum Cited Publications
21 Publications Verification
Frangula emodin
|
SARS-CoV
Casein Kinase
Autophagy
11β-HSD
|
Cancer
|
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
|
-
- HY-D0292
-
|
Fluorescent Dye
|
Others
|
1,4-Bis(mesitylamino)anthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-N0123
-
Aloin-A; Barbaloin-A
|
Others
|
Cancer
|
Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .
|
-
- HY-14393S
-
Frangula emodin-d4
|
Isotope-Labeled Compounds
SARS-CoV
Casein Kinase
Autophagy
11β-HSD
|
Cancer
|
Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].
|
-
- HY-14393R
-
Frangula emodin (Standard)
|
SARS-CoV
Casein Kinase
Autophagy
11β-HSD
|
Cancer
|
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
|
-
- HY-N0123R
-
|
Others
|
Cancer
|
Aloin (Standard) is the analytical standard of Aloin. This product is intended for research and analytical applications. Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-129042
-
|
Dyes
|
Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a Ki value of 1.2 uM .
|
-
- HY-D0943
-
Kernechtrot
|
Fluorescent Dyes/Probes
|
Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium . Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine .
|
-
- HY-D0479
-
|
Dyes
|
Disperse Blue 60 is a textile anthraquinone dye .
|
-
- HY-D0288
-
|
Dyes
|
Disperse red 86 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D1128
-
|
Dyes
|
Disperse red 151 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D1037
-
|
Dyes
|
Disperse red 50 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0687
-
|
Dyes
|
Disperse red 324 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0673
-
|
Dyes
|
Disperse red 311 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0625
-
|
Dyes
|
Disperse Red 177 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0594
-
|
Dyes
|
Disperse Red 278 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0545
-
|
Dyes
|
Disperse red 91 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0515
-
|
Dyes
|
Disperse red 73 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0513
-
|
Dyes
|
Disperse red 65 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0393
-
|
Dyes
|
Disperse red 54 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0349
-
|
Dyes
|
Disperse Red 13 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0347
-
|
Dyes
|
Disperse Red 17 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0341
-
Solvent Violet 26
|
Dyes
|
Disperse Red 11 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0315
-
|
Dyes
|
Disperse red 74 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0316
-
DR 167:1
|
Dyes
|
Disperse red 167:1 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-D0331
-
|
Dyes
|
Reactive Blue 19 is an anthraquinone dye used in the textile industry as a starting material to produce polymeric dye .
|
-
- HY-D0347R
-
|
Dyes
|
Disperse Red 17 (Standard) is the analytical standard of Disperse Red 17. This product is intended for research and analytical applications. Disperse Red 17 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
|
-
- HY-125815
-
|
Dyes
|
Reactive Blue 4 is an anthraquinone dye, as a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media. Reactive Blue 4 is phytotoxic, cytotoxic and genotoxic. Reactive Blue 4 .
|
-
- HY-D0292
-
|
Dyes
|
1,4-Bis(mesitylamino)anthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
Cat. No. |
Product Name |
Type |
-
- HY-W007618
-
|
Amino acids and Derivatives
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W007618
-
|
Biochemical Assay Reagents
|
Others
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0571
-
-
-
- HY-133860
-
-
-
- HY-N0354R
-
-
-
- HY-117732
-
-
-
- HY-N12009
-
-
-
- HY-N10369
-
-
-
- HY-N7894
-
-
-
- HY-N7991
-
-
-
- HY-N10371
-
-
-
- HY-N0571R
-
-
-
- HY-N10939
-
-
-
- HY-N12006
-
-
-
- HY-N8022
-
-
-
- HY-130049
-
-
-
- HY-N0312
-
-
-
- HY-N7599
-
-
-
- HY-N10322
-
-
-
- HY-W031757
-
-
-
- HY-N0283
-
-
-
- HY-N0990
-
|
Anthraquinones
Source classification
Morinda citrifolia Linn.
Rubiaceae
Plants
|
Others
|
1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC50 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay .
|
-
-
- HY-N8100
-
-
-
- HY-N0354
-
|
Seeds of Cassia tora Linn.
Quinones
Structural Classification
other families
Classification of Application Fields
Leguminosae
Anthraquinones
Source classification
Other Diseases
Plants
Disease Research Fields
|
Virus Protease
Topoisomerase
Apoptosis
|
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis .
|
-
-
- HY-N8725
-
-
-
- HY-N7975
-
-
-
- HY-N0105
-
-
-
- HY-N8143
-
-
-
- HY-N1138
-
-
-
- HY-N0886
-
-
-
- HY-N1972
-
-
-
- HY-N1973
-
-
-
- HY-N7618
-
-
-
- HY-N3898
-
-
-
- HY-N8093
-
-
-
- HY-N8252
-
-
-
- HY-N0444
-
-
-
- HY-N1336
-
-
-
- HY-N2714
-
-
-
- HY-N9069
-
-
-
- HY-N8962
-
-
-
- HY-126708
-
-
-
- HY-N10833
-
-
-
- HY-N11894
-
-
-
- HY-N0311
-
-
-
- HY-W353602
-
-
-
- HY-N7619
-
-
-
- HY-N9961
-
-
-
- HY-N6082
-
-
-
- HY-N0495
-
-
-
- HY-N0495R
-
-
-
- HY-119739
-
-
- HY-N0886R
-
-
- HY-135770
-
-
- HY-13595
-
-
- HY-126597
-
-
- HY-N0444R
-
-
- HY-N1972R
-
-
- HY-N1973R
-
-
- HY-N9362
-
-
- HY-N8113
-
-
- HY-N0283R
-
-
- HY-N0365R
-
-
- HY-N7502
-
-
- HY-N10648
-
-
- HY-N10649
-
-
- HY-N5091
-
-
- HY-13595R
-
-
- HY-N7598
-
-
- HY-N0311R
-
-
- HY-N1956
-
-
- HY-N6082R
-
-
- HY-N6013
-
-
- HY-N9953
-
-
- HY-N0261
-
-
- HY-117840
-
-
- HY-N0366R
-
-
- HY-134000
-
-
- HY-N0108R
-
-
- HY-N0365
-
-
- HY-N0261R
-
-
- HY-N0108
-
-
- HY-108485
-
-
- HY-14393
-
-
- HY-N0123
-
-
- HY-14393R
-
-
- HY-N0123R
-
|
Quinones
Structural Classification
Liliaceae
Anthraquinones
Source classification
Phenols
Polyphenols
Aloe vera (L.) Burm. f.
Plants
|
Others
|
Aloin (Standard) is the analytical standard of Aloin. This product is intended for research and analytical applications. Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N0354S
-
|
Anthraquinone-d8 is the deuterium labeled Anthraquinone[1]. Anthraquinone is used as a precursor for dye formation.
|
-
-
- HY-N0283S
-
|
Diacerein-d6 is the deuterium labeled Diacerein[1]. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases[2].
|
-
-
- HY-14393S
-
|
Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].
|
-
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