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Results for "

Anti-influenza virus

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Influenza Virus (55) Virus Protease (1) Adrenergic Receptor (2) Antibiotic (4) Apoptosis (3) Bacterial (6) Cytochrome P450 (2) Disulfidptosis (3) Endogenous Metabolite (4) Ferroptosis (3) Fungal (1) HSP (3) IFNAR (1) Isotope-Labeled Compounds (1) Orthopoxvirus (2) PDGFR (1) PROTACs (1) Reactive Oxygen Species (3) SARS-CoV (4) STING (1) VEGFR (1)
By Research Areas:	Cancer (11) Endocrinology (2) Infection (54) Inflammation/Immunology (9) Metabolic Disease (3) Neurological Disease (3)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Influenza Virus Dengue virus Virus Protease

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0338

Rimantadine 1-Rimantadine	Influenza Virus	Infection
Rimantadine (Flumadine) is an anti-influenza virus drug.

HY-B0338A

Rimantadine hydrochloride	Influenza Virus	Infection
Rimantadine hydrochloride is an oral anti-influenza virus A compound.

HY-W013794

Salcomine N,N′-Bis(salicylidene)ethylenediaminocobalt(II)	Others	Infection
Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O₂ and oxidation catalysts. Salcomine has anti-influenza virus activity .

HY-N2264

Wulignan A1	Influenza Virus	Infection
Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu agent resistant virus strain) activities .

HY-162793

RdRP-IN-8	Influenza Virus	Infection
RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC₅₀=0.13 μM) .

HY-161983

Neuraminidase-IN-22	Influenza Virus	Infection
Neuraminidase-IN-22 (compound 3e) is a potent, selective and orally active neuraminidase inhibitor with an IC₅₀ value of 0.03 µM. Neuraminidase shows cytotoxicity and anti-influenza A virus activity .

HY-147654

PROTAC Hemagglutinin Degrader-1	PROTACs Influenza Virus	Infection
PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent *PROTAC influenza* hemagglutinin (HA)** degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity .

HY-162680

OSC-GCDI(P)	Influenza Virus	Infection
OSC-GCDI(P) is a broad-spectrum orally active anti-influenza virus agent that exhibits significant inhibitory effects against both wild-type and Oseltamivir (HY-13317) resistant (H275Y) influenza virus strains in mouse infection models. OSC-GCDI(P) is capable of preventing not only wild-type influenza viruses but also OS-resistant variants with NA(H275Y) .

HY-168510

ATV03	Influenza Virus	Infection
ATV03 is an anti-influenza virus agent with excellent anti-influenza A and B virus activity. ATV03 inhibits anti-influenza A (H3N2) and anti-influenza B with EC₅₀ values of 0.78 nM and 2.02 nM, respectively. ATV03 exerts anti-influenza activity by inhibiting polymerase acidic protein (PA) and RNA-dependent RNA polymerase (RdRp), as well as disrupting nuclear protein .

HY-156288

Anti-Influenza agent 5	Influenza Virus	Infection
Anti-Influenza agent 5 (Compound IIB-2), chalcone-like derivative, is an influenza nuclear export inhibitor. Anti-Influenza agent 5 has inhibitory effects on oseltamivir-resistant strains. Anti-Influenza agent 5 can impede virus proliferation by blocking the export of influenza virus nucleoprotein .

HY-145586

Onradivir ZSP1273	Influenza Virus	Infection
Onradivir is a potent anti-influenza *virus* agent .

HY-145586A

Onradivir monohydrate ZSP1273 monohydrate	Influenza Virus	Infection
Onradivir monohydrate is a potent anti-influenza *virus* agent .

HY-14818A

Laninamivir octanoate CS-8958	Influenza Virus	Infection
Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .

HY-14818C

Laninamivir octanoate hydrate CS-8958 hydrate	Influenza Virus	Infection
Laninamivir octanoate hydrate (CS-8958 hydrate), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate hydrate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses .

HY-135646

Eleutheroside B1	Influenza Virus	Infection Inflammation/Immunology
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human **influenza virus efficacy, with an IC₅₀** value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .

HY-147974

HSP90-IN-14	HSP Influenza Virus	Infection
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a K_d of 0.26 μM. HSP90-IN-14 shows *anti-influenza* virus activity in MDCK cells, with EC₅₀ values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively .

HY-P99699

Lesofavumab MHAB5553A; RG70026	Influenza Virus	Infection
Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

HY-B0338AR

Rimantadine hydrochloride (Standard)	Influenza Virus	Infection
Rimantadine (hydrochloride) (Standard) is the analytical standard of Rimantadine (hydrochloride). This product is intended for research and analytical applications. Rimantadine hydrochloride is an oral anti-influenza virus A compound.

HY-122261

Spiroamantadine DU-34569 maleate	Others	Infection
Spiroamantadine (DU-34569 maleate) is a compound related to Amantadine (HY-B0402) with anti-influenza virus activity .

HY-B0272

Rifampicin 20+ Cited Publications Rifampin; Rifamycin AMP	Bacterial Influenza Virus Antibiotic Orthopoxvirus	Infection Cancer
Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza *virus* activities. Rifampicin shows anti-orthopoxvirus activity.

HY-165142

Aureonitol	Fungal	Others
Aureonitol is a compound isolated from fungi that has anti-influenza activity by inhibiting the surface glycoprotein hemagglutinin of influenza virus and has potential value for compound development.

HY-149263

HAA-09	Influenza Virus Virus Protease	Infection
HAA-09 is an orally active and potent anti-influenza agent, targeting the influenza PB2_cap binding domain. HAA-09 displays potent anti-influenza A virus activity, with an EC₅₀ of 0.03 μM. HAA-09 shows polymerase inhibition, with an IC₅₀ of 0.06±0.004 μM. HAA-09 blocks virus replication without causing obvious cytotoxicity .

HY-148309

Anti-Influenza agent 4	Influenza Virus	Infection
Anti-Influenza agent 4 is a potent and selective **influenza virus inhibitor with EC₅₀**s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively .

HY-15230

Geldanamycin 25+ Cited Publications	HSP Bacterial Influenza Virus Antibiotic	Infection Inflammation/Immunology Cancer
Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.

HY-143492

Influenza virus-IN-1	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-1 (compound 14) is a potent **influenza A virus inhibitor with an EC₅₀ of 2.46 µM and CC₅₀** of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities .

HY-143493

Influenza virus-IN-2	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-2 (compound 19) is a potent **influenza virus inhibitor with an EC₅₀ of 2.58 µM and CC₅₀** of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities .

HY-N7915

Nepasaikosaponin K	Influenza Virus	Infection
Nepasaikosaponin K is an *anti-influenza* agent. Nepasaikosaponin K shows an EC₅₀ of 17.91 μM against influenza virus A/WSN/33 (H1N1) in 239T-Gluc cells .

HY-B0272R

Rifampicin (Standard) Rifampin (Standard); Rifamycin AMP (Standard)	Bacterial Influenza Virus Antibiotic Orthopoxvirus	Infection Cancer
Rifampicin (Standard) is the analytical standard of Rifampicin. This product is intended for research and analytical applications. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza *virus* activities. Rifampicin shows anti-orthopoxvirus activity.

HY-N6025

Clemastanin B	Influenza Virus	Infection Inflammation/Immunology
Clemastanin B, a lignin, has potent *anti-influenza* activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .

HY-14904A

Umifenovir hydrochloride 5+ Cited Publications	Influenza Virus SARS-CoV	Infection
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an **anti-influenza virus** agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-N0224A

Goitrin (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone	Influenza Virus	Metabolic Disease
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .

HY-111026

PPQ-581	Influenza Virus	Infection
PPQ-581 is an anti-influenza agent with an EC₅₀ of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation .

HY-155514

HA-IN-1	Influenza Virus	Inflammation/Immunology
HA-IN-1 (compound 5g) is a Hemagglutinin (HA) ligand with high affinity, targeting to the trypsin cleavage site of HA. HA-IN-1 inhibits HA-mediated membrane fusion and reduces the pulmonary virus titer in vivo. HA-IN-1 is a potential influenza A virus (IAV) inhibitor, and an anti-influenza agent .

HY-14904

Umifenovir 5+ Cited Publications	SARS-CoV Influenza Virus	Infection
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an **anti-influenza virus** agent. Umifenovir could effectively inhibit the fusion of virus with host cells . Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro . Umifenovir shows anti-inflammatory activity .

HY-15511

Tyrphostin A9 3 Publications Verification Tyrphostin 9; Malonoben	VEGFR Influenza Virus PDGFR	Infection Cancer
Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has **anti-influenza virus** activities.

HY-15230R

Geldanamycin (Standard)	HSP Bacterial Influenza Virus Antibiotic	Infection Inflammation/Immunology Cancer
Geldanamycin (Standard) is the analytical standard of Geldanamycin. This product is intended for research and analytical applications. Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.

HY-155476

Influenza virus-IN-8	Influenza Virus	Infection
Influenza virus-IN-8 (compound A4) is an inhibitor of influenza virus (Influenza Virus) that induces viral nucleoprotein (NP) aggregation and prevents its nuclear accumulation. Influenza virus-IN-8 has broad-spectrum anti-influenza activity and can inhibit the replication and transcription of influenza A virus. Influenza virus-IN-8 also inhibits Oseltamivir (HY-13317)-resistant H1N1/pdm09 strains .

HY-14904AR

Umifenovir hydrochloride (Standard)	Influenza Virus SARS-CoV	Infection
Umifenovir (hydrochloride) (Standard) is the analytical standard of Umifenovir (hydrochloride). This product is intended for research and analytical applications. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an **anti-influenza virus** agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-161820

IAV-IN-3	Influenza Virus	Infection
IAV-IN-3 (Compound (R,S)-16s) is an anti-influenza A virus (IAV) agent (EC₅₀ = 0.134 μM) with weak cytotoxicity (CC₅₀ = 15.35 μM for MDCK cells). IAV-IN-3 inhibits IAV polymerase with an IC₅₀ of 0.045 μM .

HY-151967

Anti-IAV agent 1	Influenza Virus	Infection
Anti-IAV agent 1 (Compound (R)-1a) is an orally active anti-influenza *A virus* (IAV) agent with IC₅₀**s of 0.03 and 0.06 μM against IAV H1N1 and Oseltamivir-resistant IAV H1N1 strains, respectively .

HY-164390

6′SLN Neu5Acα2-6Galβ1-4GlcNAc	Endogenous Metabolite	Infection Cancer
6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs .

HY-14904R

Umifenovir (Standard)	SARS-CoV Influenza Virus	Infection
Umifenovir (Standard) is the analytical standard of Umifenovir. This product is intended for research and analytical applications. Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an **anti-influenza virus** agent. Umifenovir could effectively inhibit the fusion of virus with host cells . Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro . Umifenovir shows anti-inflammatory activity .

HY-10964

Vadimezan 40+ Cited Publications DMXAA; ASA-404	STING IFNAR Influenza Virus	Infection Cancer
Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan has anti-influenza virus H1N1-PR8 activities.

HY-107201

β-Cyclodextrin 5+ Cited Publications Betadex	Influenza Virus	Infection
β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.

HY-N0482

Phillyrin 4 Publications Verification	Cytochrome P450 Influenza Virus Bacterial	Infection Inflammation/Immunology Cancer
Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .

HY-163659

Anti-Influenza agent 6	Influenza Virus	Infection
Anti-Influenza agent 6 (compound 19b) shows inhibitory activity against A/WSN/33/H1N1 (EC₅₀ = 0.015 μM) and influenza B virus Yamagata/16/88 (EC₅₀ = 0.073 μM) and Victotis/2/87 (EC₅₀ = 0.067 μM) .

HY-N0440

Germacrone 1 Publications Verification	Influenza Virus	Infection
Germacrone is isolated from turmeric and has anti-influenza virus, anti-cancer, and neuroprotective activity. Germacrone inhibits the proliferation of human hepatoma cell lines by downregulating CDK1 and Bcl-2/Bcl-xl and upregulating p21 and Bax, leading to cell cycle arrest in the G2/M phase and apoptosis. Germacrone targets H1N1 and H3N2 influenza A viruses as well as influenza B viruses, significantly reducing viral titers in the lungs in animal models .

HY-N0761

Isoferulic acid 3-Hydroxy-4-methoxycinnamic acid	Adrenergic Receptor Influenza Virus	Infection Metabolic Disease Endocrinology
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC₅₀=1.4 µM) to enhance secretion of β-endorphin (EC₅₀=52.2 nM) and increase glucose use. Isoferulic acid also has **anti-influenza virus** activities.

HY-N0440R

Germacrone (Standard)	Influenza Virus	Infection
Germacrone (Standard) is the analytical standard of Germacrone. This product is intended for research and analytical applications. Germacrone is isolated from turmeric and has anti-influenza virus, anti-cancer, and neuroprotective activity. Germacrone inhibits the proliferation of human hepatoma cell lines by downregulating CDK1 and Bcl-2/Bcl-xl and upregulating p21 and Bax, leading to cell cycle arrest in the G2/M phase and apoptosis. Germacrone targets H1N1 and H3N2 influenza A viruses as well as influenza B viruses, significantly reducing viral titers in the lungs in animal models .

HY-N0482R

Phillyrin (Standard)	Cytochrome P450 Influenza Virus Bacterial	Infection Inflammation/Immunology Cancer
Phillyrin (Standard) is the analytical standard of Phillyrin. This product is intended for research and analytical applications. Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .

Cat. No.	Product Name	Target	Research Area

HY-P99699

Lesofavumab MHAB5553A; RG70026	Influenza Virus	Infection
Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .

HY-P990811

Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))	Inhibitory Antibodies	Others
Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is a kind of mouse IgG2a kappa in vivo mouse antibody, targeting to influenza virus nucleoprotein. The recommend isotype control of Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)): Mouse IgG2a kappa, Isotype Control (HY-P99978).

Cat. No.	Product Name	Chemical Structure

HY-B0215S1

Acetylcysteine-15N

Acetylcysteine- ¹⁵N (N-Acetylcysteine- ¹⁵N) is the ¹⁵N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .

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