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Citric acid

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8

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1428
    Citric acid
    Maximum Cited Publications
    26 Publications Verification

    Apoptosis Endogenous Metabolite Antibiotic Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .
    Citric acid
  • HY-B1529A
    Citric acid triammonium
    Maximum Cited Publications
    26 Publications Verification

    Triammonium citrate

    Endogenous Metabolite Apoptosis Biochemical Assay Reagents Others Cancer
    Citric acid triammonium (Triammonium citrate) is formed by Citric acid (HY-N1428) reacting with ammonia in a molar ratio of 1:3. Citric acid triammonium can be used as the carbon source to prepare carbon quantum dots (CDs). Citric acid triammonium with higher nitrogen components might promote the nitrogen-based functional groups in CDs, leading to a more efficient emission-color tunability .
    Citric acid triammonium
  • HY-N1428A
    Citric acid monohydrate
    Maximum Cited Publications
    26 Publications Verification

    Endogenous Metabolite Apoptosis Antibiotic Metabolic Disease Inflammation/Immunology Cancer
    Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .
    Citric acid monohydrate
  • HY-N1428S

    Apoptosis Bacterial Endogenous Metabolite Antibiotic Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Citric acid-d4 is the deuterium labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer.
    Citric acid-d4
  • HY-N1428S1

    Apoptosis Bacterial Endogenous Metabolite Antibiotic Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Citric acid- 13C6 is the 13C-labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer.
    Citric acid-13C6
  • HY-N1428S6

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Antibiotic Cancer
    Citric acid-d4-1 is deuterated labeled Citric acid (HY-N1428) Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.
    Citric acid-d4-1
  • HY-W127841

    Biochemical Assay Reagents Others
    Citric acid-2,4-13C2 (Sodium Lauryl Sulfate) is a labeled citric acid. Citric acid is found in many fruits and vegetables, especially citrus fruits. It participates in biological processes in the body, such as the citric acid cycle.
    Citric acid-2,4-13C2
  • HY-B2201
    Citric acid trisodium
    Maximum Cited Publications
    26 Publications Verification

    Sodium citrate; Trisodium citrate anhydrous

    Apoptosis Endogenous Metabolite Metabolic Disease Cancer
    Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice .
    Citric acid trisodium
  • HY-N1428AR

    Endogenous Metabolite Apoptosis Antibiotic Metabolic Disease Inflammation/Immunology Cancer
    Citric acid (monohydrate) (Standard) is the analytical standard of Citric acid (monohydrate). This product is intended for research and analytical applications. Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .
    Citric acid monohydrate (Standard)
  • HY-N1428S3

    Apoptosis Endogenous Metabolite Antibiotic Cancer
    Citric acid- 13C3 is the 13C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].
    Citric acid-13C3
  • HY-W008606

    Citric acid monosodium salt

    Biochemical Assay Reagents Others
    Sodium citrate monobasic (Citric acid monosodium salt) is a biochemical assay reagent.
    Sodium citrate monobasic
  • HY-W009156R

    ATP Citrate Lyase HIF/HIF Prolyl-Hydroxylase Bacterial Endogenous Metabolite Infection Metabolic Disease Inflammation/Immunology Cancer
    Citric acid (tripotassium hydrate) (Standard) is the analytical standard of Citric acid (tripotassium hydrate). This product is intended for research and analytical applications. Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects .
    Citric acid tripotassium hydrate (Standard)
  • HY-W009156
    Citric acid tripotassium hydrate
    Maximum Cited Publications
    26 Publications Verification

    Potassium citrate monohydrate

    ATP Citrate Lyase HIF/HIF Prolyl-Hydroxylase Bacterial Endogenous Metabolite Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects .
    Citric acid tripotassium hydrate
  • HY-B1610
    Sodium citrate dihydrate
    Maximum Cited Publications
    26 Publications Verification

    Trisodium citrate dihydrate; Citric acid trisodium salt dihydrate

    Bacterial Endogenous Metabolite Apoptosis Infection Cardiovascular Disease Cancer
    Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .
    Sodium citrate dihydrate
  • HY-N9542

    Others Others
    Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.
    Dimethyl Citric acid
  • HY-W009362
    DL-Isocitric acid trisodium salt
    1 Publications Verification

    Endogenous Metabolite Others
    DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
    DL-Isocitric acid trisodium salt
  • HY-P2993

    ICDH; IDH

    Isocitrate Dehydrogenase (IDH) Metabolic Disease Cancer
    Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) + to NAD(P)H, it plays important roles in cellular metabolism .
    Isocitrate dehydrogenase, Porcine heart
  • HY-128851

    Fatty Acid Synthase (FASN) Endogenous Metabolite Metabolic Disease Cancer
    Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
    Coenzyme A
  • HY-128851A

    Endogenous Metabolite Fatty Acid Synthase (FASN) Metabolic Disease Cancer
    Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
    Coenzyme A trilithium
  • HY-128851B

    Endogenous Metabolite Fatty Acid Synthase (FASN) Metabolic Disease Cancer
    Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
    Coenzyme A sodium
  • HY-W009362R

    Endogenous Metabolite Others
    DL-Isocitric acid (trisodium salt) (Standard) is the analytical standard of DL-Isocitric acid (trisodium salt). This product is intended for research and analytical applications. DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
    DL-Isocitric acid trisodium salt (Standard)
  • HY-W009362S

    Isotope-Labeled Compounds Others
    DL-Isocitric acid- 13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
    DL-Isocitric acid-13C4 trisodium salt
  • HY-W010382

    2-Oxosuccinic acid

    Endogenous Metabolite Reactive Oxygen Species Metabolic Disease
    Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .
    Oxaloacetic acid
  • HY-137808

    Succinyl-CoA sodium

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Succinyl-Coenzyme A (Succinyl-CoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A sodium can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B12 deficiency (resulting in a deficiency in Succinyl-Coenzyme A synthesis) .
    Succinyl-Coenzyme A sodium
  • HY-W142140

    N-Methylvaline

    Amino Acid Derivatives Others
    N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability .
    N-Methyl-DL-valine
  • HY-134539
    IMT1
    3 Publications Verification

    Oxidative Phosphorylation Mitochondrial Metabolism DNA/RNA Synthesis Metabolic Disease Cancer
    IMT1 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases .
    IMT1
  • HY-W416357

    Biochemical Assay Reagents Others
    Sodium citrate monobasic (Citric acid monosodium salt) is a biochemical assay reagent.
    Methyl 2-acetamido-2-deoxy-4,6-O-benzlydene-O-β-D-glucopryanoside
  • HY-W017524

    Endogenous Metabolite Others
    2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.
    2-Methylpentanedioic acid
  • HY-W011602

    Biochemical Assay Reagents Others
    Triethyl citrate is an ester of citric acid. Triethyl citrate can be used as a plasticizer for cellulosic plastic-based nanocomposites .
    Triethyl citrate
  • HY-W016814
    (Z)-Aconitic acid
    1 Publications Verification

    cis-Aconitic acid

    Endogenous Metabolite Others
    (Z)-Aconitic acid (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
    (Z)-Aconitic acid
  • HY-101765

    Cannabinoid Receptor Neurological Disease
    GW 833972A is a selective CB2 receptor agonist. GW 833972A inhibits induced nerve depolarization and citric acid-induced cough in animal models .
    GW 833972A
  • HY-N10620

    Others Inflammation/Immunology
    Melitidin is a flavanone glycoside, that can be isolated from Citrus grandis 'Tomentosa'. Melitidin shows a good antitussive effect on cough induced by citric acid in Guinea pig .
    Melitidin
  • HY-P2739

    Others Others
    Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .
    Citrate synthase
  • HY-W011602R

    Biochemical Assay Reagents Others
    Triethyl citrate (Standard) is the analytical standard of Triethyl citrate. This product is intended for research and analytical applications. Triethyl citrate is an?ester?of?citric acid. Triethyl citrate can be?used as a?plasticizer?for cellulosic plastic-based nanocomposites .
    Triethyl citrate (Standard)
  • HY-W115798

    Magnesium citrate tribasic nonahydrate, 99%

    Biochemical Assay Reagents Others
    Trimagnesium dicitrate nonahydrate, 99% (Magnesium citrate tribasic nonahydrate, 99%) is an orally active magnesium salt of citric acid in the nonahydrate form. Trimagnesium dicitrate nonahydrate, 99% used as a stabilizer and anticaking agent in food supplements in solid and chewable forms .
    Trimagnesium dicitrate nonahydrate, 99%
  • HY-W016814R

    Endogenous Metabolite Others
    (Z)-Aconitic acid (Standard) is the analytical standard of (Z)-Aconitic acid. This product is intended for research and analytical applications. (Z)-Aconitic acid (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
    (Z)-Aconitic acid (Standard)
  • HY-W010382S

    2-Oxosuccinic acid-13C4

    Endogenous Metabolite Isotope-Labeled Compounds Metabolic Disease
    Oxaloacetic acid- 13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis[1][2][3].
    Oxaloacetic acid-13C4
  • HY-B1610L

    Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 6.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 6.0 is used for RNA isolation and antigens detection in fixed tissue .
    Sodium Citrate Buffer, 0.5M, pH 6.0
  • HY-W015883
    Fumaric acid
    1 Publications Verification

    Endogenous Metabolite NF-κB p38 MAPK Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid
  • HY-W142140A

    N-Methylvaline hydrochloride

    Others Cancer
    N-Methyl-DL-valine (N-Methylvaline) hydrochloride is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine hydrochloride involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability .
    N-Methyl-DL-valine hydrochloride
  • HY-W016814S

    cis-Aconitic acid-13C6

    Isotope-Labeled Compounds Others
    (Z)-Aconitic acid- 13C6 is the 13C-labeled (Z)-Aconitic acid (HY-W016814). (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
    (Z)-Aconitic acid-13C6
  • HY-W015883R

    Endogenous Metabolite NF-κB p38 MAPK Metabolic Disease Inflammation/Immunology
    Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
    Fumaric acid (Standard)
  • HY-W013762

    Biochemical Assay Reagents Others
    Tributyl citrate is a citric acid ester. Tributyl citrate can be used as an excipient, such as plasticizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Tributyl citrate
  • HY-B1610K

    Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 5.5, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer 0.5M pH 5.5 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer 0.5M pH 5.5 is the preferred solution for most antibodies. .
    Sodium Citrate Buffer, 0.5M, pH 5.5
  • HY-B1610M

    Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 6.5, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 6.5 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer, 0.5M, pH 6.5 is the preferred solution for most antibodies .
    Sodium Citrate Buffer, 0.5M, pH 6.5
  • HY-W013762R

    Biochemical Assay Reagents Others
    Tributyl citrate (Standard) is the analytical standard of Tributyl citrate. This product is intended for research and analytical applications. Tributyl citrate is a citric acid ester. Tributyl citrate can be used as an excipient, such as plasticizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Tributyl citrate (Standard)
  • HY-B1610N
    Sodium Citrate Buffer, 0.1M, pH 4.0
    1 Publications Verification

    Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.1M, pH 4.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.1M, pH 4.0 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer, 0.1M, pH 4.0 is the preferred solution for most antibodies . Sodium citrate buffer, 0.1M, pH 4.0 is used in the hydration of liposome film .
    Sodium Citrate Buffer, 0.1M, pH 4.0
  • HY-B1610J

    Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 5.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 5.0 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer, 0.5M, pH 5.0 is the preferred solution for most antibodies . Sodium citrate buffer, 0.5M, pH 5.0 is used as solution for captisol in animal tumor models .
    Sodium Citrate Buffer, 0.5M, pH 5.0
  • HY-19633A

    Others Neurological Disease
    CS-003 is a triple neurokinin receptor antagonist with activity in inhibiting neurokinin-related respiratory diseases. CS-003 exhibits high affinity for human neurokinin 1, 2 and 3 receptors, withKi values of 2.3 nM, 0.54 nM and 0.74 nM respectively. The Ki values of CS-003 on the guinea pig neurokinin receptor are 5.2 nM, 0.47 nM and 0.71 nM respectively, showing superior inhibitory effect. CS-003 significantly inhibits the formation of inositol phosphate involving substance P, neurokinin A and neurokinin B through competitive antagonism. CS-003 significantly inhibits citric acid-induced cough, and its effect is better than other selective neurokinin receptor antagonists .
    CS-003

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