Search Result
Results for "
DMTS
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
13
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-43060
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- HY-21997
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DNA/RNA Synthesis
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Others
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Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis .
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- HY-45409
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- HY-N11421
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23-DMT; 23-Demycinosyltylosin
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Bacterial
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Infection
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23-O-Demycinosyltylosin (23-DMT) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity .
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-
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- HY-150658S
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-
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- HY-W854187
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5'-DMT-2'-OMe-rG(N-Ac) Phosphoramidite
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DNA/RNA Synthesis
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Others
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2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac)) Phosporamiditeyes 2'-Ome-Ac-G (5'-DMT-2'-OMe-rG(N-Ac))Phosphoramidite.
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-
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- HY-W013068S1
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DNA/RNA Synthesis
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Others
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DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W013068S2
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-
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- HY-153249
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DNA/RNA Synthesis
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Others
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DMT-2'-F-Cytidine Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
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- HY-W036167
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DNA/RNA Synthesis
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Others
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DMT-2'-F-dA Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W013059R
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W115309
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5'-DMT-2'-F-ibu-dG
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
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- HY-W008848S1
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-
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- HY-W013059S1
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DA-CE phosphoramidite-15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W018179
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-
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- HY-W093086
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-
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- HY-153251
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DNA/RNA Synthesis
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Others
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DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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-
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- HY-153253
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DNA/RNA Synthesis
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Others
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DMT-2'-O-Methyladenosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W579407
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DNA/RNA Synthesis
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Others
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DMT-2'-OMe-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
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- HY-W579408
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DNA/RNA Synthesis
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Others
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DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-126302
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Ferroportin
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Metabolic Disease
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DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo .
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- HY-21713
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DNA/RNA Synthesis
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Others
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DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-168014
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5-OMe DMT
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Others
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Neurological Disease
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5-Methylthio DMT is a tryptamine. 5-Methylthio DMT is promising for research of hallucinogen .
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- HY-W013068S
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DNA/RNA Synthesis
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Others
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DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W010744
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5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
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Nucleoside Antimetabolite/Analog
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Others
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DMT-dI (5'-O-DMT-dI) is a deoxyuridine which can be used in the preparation of convertible nucleoside derivatives .
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- HY-W579410
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DNA/RNA Synthesis
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Others
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DMT-2'-F-6-chloro-dA phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
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- HY-W783407
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5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite
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DNA/RNA Synthesis
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Others
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Ac-rG (5'-DMT-2'-TBDMS-rG(N-Ac)) Phosporamidite is an acetylated guanosine ribonucleotide.
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-
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- HY-W008848S
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-
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- HY-W008849S
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- HY-W013059S
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DA-CE phosphoramidite-13C10,15N5
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-160884
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DNA/RNA Synthesis
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Others
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DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides .
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- HY-45491
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2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Others
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Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
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- HY-W700549
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- HY-126301
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Ferroportin
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Inflammation/Immunology
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DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo .
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-
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- HY-W101391
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2'-O-Me-U Phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
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-
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- HY-46317
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DNA/RNA Synthesis
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Others
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DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding .
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-
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- HY-W013059A
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L-DA-CE phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-L-dA(bz) Phosphoramidite (L-DA-CE phosphoramidite; compound 20c) is typically used in the synthesis of DNA. DMT-L-dA(bz) Phosphoramidite can be used in studying DNA-drug interactions .
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- HY-164252
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5′-O-Trityl-2′-deoxy-2′-fluorouridine
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DNA/RNA Synthesis
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Others
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DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
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- HY-138607
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-
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- HY-138613
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-
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- HY-W114886
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-
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- HY-154413
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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-
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- HY-W115186
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-45492
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2'-F-ibu-dG Phosphoramidite
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Nucleoside Antimetabolite/Analog
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Others
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DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
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- HY-104014
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Others
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DMT-2'O-MOE-rG(ib) Phosphoramidite (1g), belonging to the amide family of trivalent phosphate H3PO3, is a derivative of nucleotides and guanosine and can be used in the stereochemical synthesis of phosphorothioate oligonucleotides .
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- HY-W013068
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-
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- HY-138601
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-
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- HY-W048482S4
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DMT-2'O-TBDMS-rU phosphoramidite-15N
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W013059
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DA-CE phosphoramidite
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DNA/RNA Synthesis
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Others
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DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
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- HY-W008849
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- HY-W008848
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- HY-W570893
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DNA/RNA Synthesis
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Others
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DMT-LNA-G phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-W048482S3
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DMT-2'O-TBDMS-rU phosphoramidite-15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138581
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- HY-138608
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- HY-138585
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- HY-49000
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DNA/RNA Synthesis
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Others
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DMT-locMeC(bz) phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49210
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DNA/RNA Synthesis
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Others
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DMT-locG(ib) Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49200
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W048482S2
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DMT-2'O-TBDMS-rU phosphoramidite-13C9
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138605
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- HY-138606
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- HY-138609
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- HY-139988
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DNA/RNA Synthesis
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Others
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2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-164181
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- HY-B1311
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SKF-525A; U-5446; RP-5171
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Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases .
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- HY-138586
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- HY-164249
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DNA/RNA Synthesis
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Others
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DMT-rG(Ac)Is with DMTProtecting Group (Protect 5'end), acetylated guanosine ribonucleotide.
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- HY-132136
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DNA/RNA Synthesis
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Others
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DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing .
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- HY-21545
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- HY-W102322
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- HY-138610
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- HY-154366
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N1-Methylpseudouridine CEP
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Nucleoside Antimetabolite/Analog
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Cancer
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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W784557
-
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Biochemical Assay Reagents
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Others
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O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
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- HY-B1311R
-
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Cytochrome P450
Monoamine Oxidase
Bcl-2 Family
Survivin
PARP
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Neurological Disease
Inflammation/Immunology
Cancer
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|
Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [4] .
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- HY-W048482S1
-
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DMT-2'O-TBDMS-rU phosphoramidite-13C9,15N2
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-138600
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-
- HY-W008848A
-
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Others
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Metabolic Disease
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DMT-L-dG(ib) Phosphoramidite (Compound 20D) is a nucleoside phosphoramidite that can be used for nucleotide assembly on solid supports .
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- HY-138604
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- HY-104017
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Nucleoside Antimetabolite/Analog
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Cancer
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DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-138106
-
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Amino Acid Derivatives
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Others
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Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
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- HY-43059
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-
- HY-138611
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-
- HY-138603
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-
- HY-138614
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-
- HY-138612
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- HY-W000665
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Dmt
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Opioid Receptor
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Neurological Disease
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|
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
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-
- HY-W077279
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N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
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DNA/RNA Synthesis
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Others
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5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
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- HY-21601
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-
- HY-W336559
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DNA/RNA Synthesis
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Others
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5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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-
- HY-12619
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HSP
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Cancer
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DMT003096 is a HSP70 inhibitor. HSP70 has been reported to be upregulated in various cancers including breast, lung, colon, and cervix .
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- HY-43058
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-
- HY-138602
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-
- HY-20140
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-
- HY-138598
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-
- HY-48873
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DNA/RNA Synthesis
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Others
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5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-46369
-
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DNA/RNA Synthesis
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Others
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1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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-
- HY-W087199
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DNA/RNA Synthesis
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Others
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N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-152970
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Nucleoside Antimetabolite/Analog
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Others
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7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
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-
- HY-W114328
-
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N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
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Nucleoside Antimetabolite/Analog
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Others
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DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
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-
- HY-W008662
-
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Filovirus
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Infection
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|
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
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- HY-104039
-
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Nucleoside Antimetabolite/Analog
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Cancer
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2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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-
- HY-W010702
-
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N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
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DNA/RNA Synthesis
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Others
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5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
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- HY-154019
-
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Nucleoside Antimetabolite/Analog
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Cancer
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|
N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154410
-
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Nucleoside Antimetabolite/Analog
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Cancer
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5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
|
-
- HY-101528
-
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iGluR
|
Neurological Disease
|
|
IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging .
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- HY-152978
-
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Nucleoside Antimetabolite/Analog
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Others
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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-
- HY-154604
-
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Nucleoside Antimetabolite/Analog
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Cancer
|
|
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
|
-
- HY-154363
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154309
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154267
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152979
-
|
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154229
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154441
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154450
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-154030
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154207
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154221
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154260
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-152973
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-152988
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-138589
-
|
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154350
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-W097792
-
|
5'-O-DMT-dU
|
DNA/RNA Synthesis
|
Others
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-152984
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154548
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-154464
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
-
- HY-152983
-
|
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154339
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-154419
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-45281
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
-
- HY-W141392
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W392836
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
-
- HY-W010706
-
|
5'-O-DMT-N4-Bz-dC
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-21997
-
|
|
Gene Sequencing and Synthesis
|
|
Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis .
|
-
- HY-W093086
-
-
- HY-W013068
-
-
- HY-W013059
-
-
- HY-W008849
-
-
- HY-W008848
-
-
- HY-132136
-
-
- HY-W097792
-
|
5'-O-DMT-dU
|
Gene Sequencing and Synthesis
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
-
- HY-W013059R
-
|
|
Gene Sequencing and Synthesis
|
|
DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .
|
-
- HY-W077279
-
|
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
|
Gene Sequencing and Synthesis
|
|
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-138106
-
|
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .
|
-
- HY-W000665
-
|
Dmt
|
Opioid Receptor
|
Neurological Disease
|
|
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-150658S
-
|
|
|
DMT-2′O-TBDMS-rA(ac)-1- 15N phosphoramidite is the 15N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite[1].
|
-
-
- HY-W013068S1
-
|
|
|
DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W013068S2
-
|
|
|
DMT-dT Phosphoramidite- 13C is 13C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
|
-
-
- HY-W008848S1
-
|
|
|
DMT-dG(ib) Phosphoramidite- 15N5 is the 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W013059S1
-
|
|
|
DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W013068S
-
|
|
|
DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W008848S
-
|
|
|
DMT-dG(ib) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W008849S
-
|
|
|
DMT-dC(bz) Phosphoramidite- 13C9, 15N3 is the 13C and 15N labeled DMT-dC(bz) Phosphoramidite[1]. DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W013059S
-
|
|
|
DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
-
- HY-W048482S4
-
|
|
|
rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S3
-
|
|
|
rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S2
-
|
|
|
rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W048482S1
-
|
|
|
rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-43060
-
|
|
|
Nucleosides and their Analogs
|
|
5'-DMT-3'-TBDMS-ibu-rG is is a modified nucleoside. 5'-DMT-3'-TBDMS-ibu-rG can be used in deoxyribonucleic acid synthesis.
|
-
- HY-21997
-
|
|
|
Nucleoside Phosphoramidites
|
|
Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis .
|
-
- HY-45409
-
-
- HY-W115309
-
|
5'-DMT-2'-F-ibu-dG
|
|
Nucleosides and their Analogs
|
|
DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets .
|
-
- HY-W018179
-
-
- HY-W093086
-
-
- HY-153249
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-F-Cytidine Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W036167
-
-
- HY-153251
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-153253
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-O-Methyladenosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W579407
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-OMe-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W579408
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-21713
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W010744
-
|
5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
|
|
Nucleosides and their Analogs
|
|
DMT-dI (5'-O-DMT-dI) is a deoxyuridine which can be used in the preparation of convertible nucleoside derivatives .
|
-
- HY-W579410
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'-F-6-chloro-dA phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-45491
-
|
2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
|
|
Nucleoside Phosphoramidites
|
|
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .
|
-
- HY-W700549
-
-
- HY-W101391
-
|
2'-O-Me-U Phosphoramidite
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis .
|
-
- HY-46317
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding .
|
-
- HY-164252
-
|
5′-O-Trityl-2′-deoxy-2′-fluorouridine
|
|
Nucleosides and their Analogs
|
|
DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
|
-
- HY-138607
-
|
|
|
Nucleoside Phosphoramidites
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-138613
-
|
|
|
Nucleoside Phosphoramidites
|
|
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-W114886
-
-
- HY-154413
-
|
|
|
Nucleosides and their Analogs
|
|
DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
|
-
- HY-45492
-
|
2'-F-ibu-dG Phosphoramidite
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
|
-
- HY-104014
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-2'O-MOE-rG(ib) Phosphoramidite (1g), belonging to the amide family of trivalent phosphate H3PO3, is a derivative of nucleotides and guanosine and can be used in the stereochemical synthesis of phosphorothioate oligonucleotides .
|
-
- HY-W013068
-
-
- HY-138601
-
|
|
|
Nucleoside Phosphoramidites
|
|
5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
|
-
- HY-W013059
-
-
- HY-W008849
-
-
- HY-W008848
-
-
- HY-W570893
-
-
- HY-138581
-
-
- HY-138608
-
-
- HY-138585
-
|
|
|
Nucleoside Phosphoramidites
|
|
DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
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- HY-49000
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Nucleoside Phosphoramidites
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DMT-locMeC(bz) phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49210
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Nucleoside Phosphoramidites
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DMT-locG(ib) Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-49200
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Nucleosides and their Analogs
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DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-138605
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- HY-138606
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- HY-138609
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- HY-139988
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Nucleoside Phosphoramidites
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2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-138586
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Nucleoside Phosphoramidites
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DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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- HY-164249
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- HY-132136
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- HY-21545
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- HY-W102322
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- HY-138610
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- HY-154366
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N1-Methylpseudouridine CEP
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Nucleoside Phosphoramidites
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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-138600
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- HY-138604
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- HY-104017
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Nucleoside Phosphoramidites
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DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
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- HY-43059
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5'-O-DMT-2'-O-TBDMS-ibu-rG
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Nucleoside Phosphoramidites
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5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides .
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- HY-138611
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- HY-138603
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- HY-138614
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- HY-138612
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- HY-W077279
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N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
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Nucleoside Phosphoramidites
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5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis .
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- HY-21601
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Nucleoside Phosphoramidites
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5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
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- HY-W336559
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Nucleoside Phosphoramidites
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5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-43058
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5'-O-DMT-N2-isobutyrylguanosine
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Nucleoside Phosphoramidites
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5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents .
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- HY-138602
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- HY-20140
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5'-O-(4,4'-Dimethoxytrityl)thymidine
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Nucleoside Phosphoramidites
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5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides .
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- HY-138598
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Nucleosides and their Analogs
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5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
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- HY-48873
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Nucleoside Phosphoramidites
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5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-46369
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Nucleoside Phosphoramidites
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1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W087199
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Nucleoside Phosphoramidites
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N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-152970
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Nucleosides and their Analogs
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7'-O-DMT-morpholino uracil is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
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- HY-W114328
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N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
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Nucleosides and their Analogs
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DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
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- HY-W008662
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity .
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- HY-104039
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-W010702
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N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
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Nucleoside Phosphoramidites
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5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
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- HY-154019
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Nucleoside Phosphoramidites
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N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154410
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Nucleosides and their Analogs
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5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
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- HY-152978
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154604
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Nucleoside Phosphoramidites
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1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
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- HY-154363
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Nucleosides and their Analogs
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3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154309
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Nucleoside Phosphoramidites
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3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154267
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Nucleosides and their Analogs
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5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152979
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Nucleoside Phosphoramidites
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2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154229
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Nucleosides and their Analogs
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|
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154441
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Nucleosides and their Analogs
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N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154450
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Nucleosides and their Analogs
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N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-154030
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Nucleoside Phosphoramidites
|
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N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154207
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|
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Nucleoside Phosphoramidites
|
|
2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154221
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Nucleoside Phosphoramidites
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|
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154260
-
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|
|
Nucleosides and their Analogs
|
|
N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152973
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|
|
Nucleosides and their Analogs
|
|
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-152988
-
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|
|
Nucleosides and their Analogs
|
|
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-138589
-
|
|
|
Nucleosides and their Analogs
|
|
5'-O-TBDMS-dG is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-154350
-
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|
|
Nucleoside Phosphoramidites
|
|
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-W097792
-
|
5'-O-DMT-dU
|
|
Nucleoside Phosphoramidites
|
|
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .
|
- HY-152984
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|
|
|
Nucleosides and their Analogs
|
|
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154548
-
|
|
|
Nucleosides and their Analogs
|
|
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-154464
-
|
|
|
Nucleoside Phosphoramidites
|
|
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
|
- HY-152983
-
|
|
|
Nucleoside Phosphoramidites
|
|
2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154339
-
|
|
|
Nucleoside Phosphoramidites
|
|
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-154419
-
|
|
|
Nucleosides and their Analogs
|
|
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-45281
-
|
|
|
Nucleoside Phosphoramidites
|
|
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
|
- HY-W141392
-
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|
|
Nucleoside Phosphoramidites
|
|
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
- HY-W392836
-
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|
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Nucleoside Phosphoramidites
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|
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
|
- HY-W010706
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|
5'-O-DMT-N4-Bz-dC
|
|
Nucleoside Phosphoramidites
|
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
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