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Native Proteins

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333

Inhibitors & Agonists

4

Fluorescent Dye

330

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3

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1

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1

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5

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1

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-NP010

    MMP Others
    Collagen, rat tail is a kind of collagen extracted from rat tail tendon tissue. Collagen, rat tail stimulates cell growth. Collagen, rat tail is often used as an attachment substrate for cell culture .
    Collagen, rat tail
  • HY-NP001

    CBSA

    Biochemical Assay Reagents Neurological Disease
    Cationic Bovine Serum Albumin is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic Bovine Serum Albumin a cationic protein. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
    Cationic Bovine Serum Albumin
  • HY-NP020

    E.coli DH-5 alpha protein

    Bacterial Others
    E.coli DH-5 alpha Bacterial protein is a purified native protein from E.coli DH-5 alpha bacterial .
    E.coli DH-5 alpha Bacterial protein
  • HY-NP025

    EPEC

    Bacterial Infection
    E.coli Bacterial protein is a native protein that can be isolated from E.coli .
    E.coli Bacterial protein
  • HY-NP016

    Bacterial Biochemical Assay Reagents Others
    Brucella bacterial protein is native protein that purified from Brucella for life science related research .
    Brucella bacterial protein
  • HY-158882

    Biochemical Assay Reagents Adenosine Receptor Others
    FLAC6 is a potent fluorinated detergent that can be used to solubilize membrane proteins (the native adenosine receptor A2AR, a G protein-coupled receptor, and two native transporters AcrB and BmrA). FLAC6 can maintain the structural and functional integrity of different membrane proteins .
    FLAC6
  • HY-P5428

    CDK Others
    Cdc2 kinase substrate is a biological active peptide. (The native peptide HATPPKKKRK is a substrate for cyclin-dependent protein kinase 1 (CDC2; CDK1).)
    Cdc2 kinase substrate
  • HY-D0167

    Fluorescent Dye Others
    NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
    NHS-5(6)Carboxyrhodamine
  • HY-122297

    Endogenous Metabolite Others
    H-​Arg-​Phe-​OH is an amphipathic peptide. H-​Arg-​Phe-​OH has the ability to induce native-like protein aggregation. H-​Arg-​Phe-​OH can induce aggregation of the neutral model protein yeast alcohol dehydrogenase (ADH) .
    H-​Arg-​Phe-​OH
  • HY-W615327

    Biochemical Assay Reagents Others
    Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.
    Bis-sulfone NHS ester
  • HY-W190952

    Biochemical Assay Reagents Others
    Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
    Bis-sulfone-PEG4-NHS ester
  • HY-W878827

    Biochemical Assay Reagents Others
    Bis-sulfone-PEG12-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
    Bis-sulfone-PEG12-NHS ester
  • HY-W800627

    Biochemical Assay Reagents Others
    Bis-sulfone-PEG8-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
    Bis-sulfone-PEG8-NHS ester
  • HY-P99930

    FGFR Metabolic Disease
    Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis .
    Efruxifermin
  • HY-112641A
    AkaLumine hydrochloride
    2 Publications Verification

    Fluorescent Dye Cancer
    AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
    AkaLumine hydrochloride
  • HY-112641

    Fluorescent Dye Cancer
    AkaLumine is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
    AkaLumine
  • HY-112096
    eCF506
    3 Publications Verification

    NXP900

    Src Cancer
    eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
    eCF506
  • HY-N10264

    (+)-Avrainvillamide; CJ-17,665

    Antibiotic Infection Cancer
    Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
    Avrainvillamide
  • HY-W414390

    2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%

    Biochemical Assay Reagents Others
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98% (2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%) is a detergent that can be used for the purification and crystallization of membrane-bound proteins in their native structure. It can self-assemble into micelles and vesicles in aqueous solution and can be used for the study of biomembrane models.
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%
  • HY-42984

    Biochemical Assay Reagents Others
    BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    BHQ-2 NHS
  • HY-E70565

    Endonuclease Inflammation/Immunology
    O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6×His tag at the C-terminus.
    The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn 2+.
    O-Glycoprotease
  • HY-W1005067

    Molecular Glues Hippo (MST) Estrogen Receptor/ERR Others
    EN171 is a covalent ligand that covalently targets both C38 and C96 on 14-3-3 to enhance 14-3-3 interactions with ERα, YAP and TAZ, leading to impaired estrogen receptor and Hippo pathway transcriptional activity. EN171 can not only be used as a molecular glue to enhance native protein interactions but can also be used as a covalent 14-3-3 recruiter in heterobifunctional molecules to sequester nuclear neo-substrates such as BRD4 and BLC6 into the cytosol .
    EN171
  • HY-112096S

    NXP900-d5

    Src Isotope-Labeled Compounds Cancer
    eCF506-d5 (NXP900-d5) is deuterated labeled eCF506 (HY-112096). eCF506 is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
    eCF506-d5
  • HY-116748

    PDI Phosphatase
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane is a small-molecule dithiol catalyst with a low thiol pKa value (8.3) and high reduction potential (-0.24 V), capable of mimicking PDI activity. It catalyzes the activation of scrambled ribonuclease A (scrambled ribonuclease A) and promotes the formation of native disulfide bonds, thereby significantly enhancing protein folding efficiency. Adding (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane to the culture medium of Saccharomyces cerevisiae can increase the secretion of exogenously expressed Schizosaccharomyces pombe acid phosphatase by more than threefold. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane holds great potential for applications in protein production and secretion research .
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
  • HY-NP111

    Mouse Type V collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type V collagen, from mouse intestine (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse intestine, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type V collagen, from mouse intestine
  • HY-NP0143

    SBA (Fluorescein)

    Fluorescent Dye Others
    Soybean Agglutinin (SBA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Soybean Agglutinin (SBA) Fluorescein is a biological material or organic compound that can be used in life science research .
    Soybean Agglutinin (Fluorescein)
  • HY-NP044

    Con A-AF594

    Biochemical Assay Reagents Others
    Concanacalin A-AF594 (Con A-AF594) is a kind of biological materials or organic compounds that are widely used in life science research .
    Concanacalin A-AF594
  • HY-B2196
    Gastric mucin
    2 Publications Verification

    Bacterial Antibiotic Infection Metabolic Disease
    Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.
    Gastric mucin
  • HY-NP0166

    SNA (Agarose)

    Fluorescent Dye Others
    Sambucus Nigra Lectin (Agarose) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Sambucus Nigra Lectin (Agarose) is a biological material or organic compound that can be used in life science research .
    Sambucus Nigra Lectin (Agarose)
  • HY-125865

    Casein Kinase Endogenous Metabolite Endocrinology Cancer
    Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .
    Casein
  • HY-NP150

    MAL I (Biotinylated)

    Fluorescent Dye Others
    Maackia Amurensis Lectin I Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.). Maackia Amurensis Lectin I Biotinylated is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I (Biotinylated)
  • HY-NP0202

    Human IgA

    Inflammation/Immunology
    Human Immunoglobulin A (Human IgA) is one of the most abundant immunoglobulin in humans. Serum IgA is mainly monomeric. Human Immunoglobulin A is involved in mucosal immunity .
    Human Immunoglobulin A
  • HY-NP158H

    Biochemical Assay Reagents Others
    Type II Collagen, T Cell Grade, from Rat is a T-cell dependent antigen with unique immunological features. Type II Collagen, T Cell Rat, from Bovine can be used as a stimulating antigen for T-cells in in vitro culture systems .
    Type II Collagen, T Cell Grade, from Rat
  • HY-NP123

    Porcine Type II collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type II collagen, from porcine articular cartilage (Porcine Type II collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type II collagen, from porcine articular cartilage
  • HY-NP196

    cTn

    Biochemical Assay Reagents Metabolic Disease
    Human cardiac troponin (mixture) (cTn) is a regulatory protein for muscle tissue contraction, located on the thin filaments of contractile proteins, and plays an important regulatory role in muscle contraction and relaxation .
    Human cardiac troponin (mixture)
  • HY-NP153

    LTL (Biotinylated)

    Fluorescent Dye Others
    Lotus Tetragonolobus Lectin Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.). Lotus Tetragonolobus Lectin Biotinylated is a biological material or organic compound that can be used in life science research .
    Lotus Tetragonolobus Lectin (Biotinylated)
  • HY-NP003

    Collagen

    Collagen Inflammation/Immunology
    Collagen, Type II, from bovine snout membrane is a type II collagen that can be used for cell culture . This product is enzymatically hydrolyzed collagen peptides.
    Collagen, Type II, from bovine snout membrane
  • HY-NP0136

    LEL (Fluorescein)

    Fluorescent Dye Others
    Lycopersicon esculentum (Tomato) Lectin (LEL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lycopersicon esculentum (Tomato) Lectin (LEL) Fluorescein is a biological material or organic compound that can be used in life science research .
    Lycopersicon esculentum  (Tomato) Lectin (Fluorescein)
  • HY-NP051

    Biochemical Assay Reagents Others
    Bovine Sermu Albumin-FITC is a bovine serum albumin conjugated to FITC (Ex=495 nm; Em=525 nm). Bovine Sermu Albumin-FITC can be used as a fluorescent marker to label or detect specific antigens, molecules or cellular structures .
    Bovine Serum Albumin-FITC
  • HY-NP0187

    STL (Biotinylated)

    Fluorescent Dye Others
    Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a biological material or organic compound that can be used in life science research .
    Solanum Tuberosum (Potato) Lectin (Biotinylated)
  • HY-150097

    Biochemical Assay Reagents Others
    Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. The main physiological function of Recombinant Human Serum Albumin (rHSA) is to regulate plasma pH and maintain plasma osmotic pressure .
    Recombinant Human Serum Albumin(rHSA)
  • HY-NP0135

    LTL (Fluorescein)

    Fluorescent Dye Others
    Lotus Tetragonolobus Lectin (LTL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lotus Tetragonolobus Lectin (LTL) Fluorescein is a biological material or organic compound that can be used in life science research .
    Lotus Tetragonolobus Lectin (Fluorescein)
  • HY-NP115

    Chick Type XI collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type XI collagen, from chick articular cartilage (Chick Type XI collagen, immunization grade) is an immune grade collagen derived from chick articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type XI collagen, from chick articular cartilage
  • HY-NP157D

    Biochemical Assay Reagents Others
    Type I Collagen, T Cell Grade, from Porcine has unique immunological features and plays an important role in the structure and function of skin, bones, tendons, etc. Type I Collagen, T Cell Grade, from Porcine can be used as a stimulating antigen for T-cells in in vitro culture systems .
    Type I Collagen, T Cell Grade, from Porcine
  • HY-NP133A

    4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II

    Biochemical Assay Reagents Inflammation/Immunology
    NP-KLH,Type II (4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II) is a 4-Hydroxy-3-nitrophenylacetyl (NP) hapten. NP-KLH,Type II can be used for study as a carrier protein in immunological research .
    NP-KLH,Type II
  • HY-NP0175

    DSL,Biotinylated

    Fluorescent Dye Others
    Datura Stramonium Lectin (DSL,Biotinylated) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Datura Stramonium Lectin (DSL,Biotinylated) is a biological material or organic compound that can be used in life science research .
    Datura Stramonium Lectin (Biotinylated)
  • HY-NP185

    Biochemical Assay Reagents Others
    Chicken Tenascin,suitable for cell culture 是一种糖蛋白,可形成二硫键连接的六聚体。Chicken Tenascin,suitable for cell culture 由重复的结构域组成,包括 EGF 样重复序列、纤连蛋白 III 型重复序列和与纤维蛋白原同源的区域。Chicken Tenascin,suitable for cell culture 可用于细胞培养。
    Chicken Tenascin,suitable for cell culture
  • HY-P3160
    Fibronectin
    4 Publications Verification

    Integrin Cardiovascular Disease Inflammation/Immunology
    Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
    Fibronectin
  • HY-NP126

    Porcine Type XI collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type XI collagen, from porcine articular cartilage
  • HY-NP058

    OVA-AF594

    Biochemical Assay Reagents Others
    Ovalbumin-AF594 is a biochemical reagent conjugated to fluorescein AF594 (Ex=590 nm; Em=617 nm). Ovalbumin-AF594 can be used to label or detect specific antigens, molecules or cellular structures .
    Ovalbumin-AF594

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