Search Result
Results for "
Organophosphate
" in MedChemExpress (MCE) Product Catalog:
5
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-114899
-
-
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- HY-B1738A
-
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Cholinesterase (ChE)
|
Neurological Disease
|
Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning .
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- HY-B1200
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2-PAM chloride
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Cholinesterase (ChE)
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Neurological Disease
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Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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- HY-B1542
-
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Cholinesterase (ChE)
|
Neurological Disease
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Benactyzine is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine is an anticholinergic drug. Benactyzine has the potential for organophosphate poisoning research .
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-
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- HY-144762
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-
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- HY-114899S
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-
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- HY-114899R
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Cholinesterase (ChE)
Parasite
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Neurological Disease
|
Azamethiphos (Standard) is the analytical standard of Azamethiphos. This product is intended for research and analytical applications. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .
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- HY-B1738
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Cholinesterase (ChE)
|
Neurological Disease
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Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning .
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-
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- HY-B1738B
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|
Cholinesterase (ChE)
|
Neurological Disease
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Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning .
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- HY-B1200R
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Cholinesterase (ChE)
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Neurological Disease
|
Pralidoxime (chloride) (Standard) is the analytical standard of Pralidoxime (chloride). This product is intended for research and analytical applications. Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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-
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- HY-B2029
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|
Parasite
|
Infection
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Phosalone is a member of the organophosphate family of insecticides.
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-
-
- HY-17523
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-
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- HY-W653780
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DMTP; O,O-Dimethyl phosphorothionate
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Endogenous Metabolite
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Others
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Dimethyl phosphorothioate (DMTP; O,O-Dimethyl phosphorothionate) is a metabolite of organophosphate pesticides. Dimethyl phosphorothioate can be used as a biomonitoring indicator for assessing pesticide exposure levels of organophosphate pesticides and identifying high-risk groups .
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-
-
- HY-B1113
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Dimpylate
|
Parasite
|
Infection
|
Diazinon is a thiophosphoric acid ester, is a nonsystemic organophosphate insecticide, used to control cockroaches, silverfish, ants, and fleas.
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-
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- HY-B1093
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|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction .
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- HY-146959
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-
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- HY-B1120
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Temefos
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Parasite
|
Infection
|
Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae.
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-
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- HY-W349628
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Drug Metabolite
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Others
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Dibutyl 3-hydroxybutyl phosphate is a predominant metabolite of tris( n-butyl) phosphate (TNBP). TNBP is a commonly used alkyl organophosphate ester .
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- HY-B1542A
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research .
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-
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- HY-118077
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Others
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Others
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RE 11775 (m-tert-butylphenyl-N-methyl-N-(phenylthio) carbonate) is a new carbonate ester with unusually high toxicity to mosquito larvae. Laboratory and field evaluations have shown that it has potential for use in controlling sensitive and organophosphate-resistant larval and adult stages of Aedes nigromaculis (Ludlow). Preliminary studies also suggest that RE 11775 may also be useful for controlling sensitive and organophosphate-resistant Culex spccies. This new carbonate ester is relatively safe, with no adverse effects found in current testing.
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- HY-D0994
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4-MUP; MUP
|
Phosphatase
|
Others
|
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
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-
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- HY-116857
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|
Fungal
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Others
|
Ditalimfos is an organophosphate fungicide. Ditalimfos is mainly used in agriculture to control fungal diseases of crops. Ditalimfos can be used for fungal resistance studies and risk assessment of residues in the environment .
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-
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- HY-W341259
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|
Parasite
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Infection
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Isazofos is a broad-spectrum organophosphate insecticide-nematicide that controls numerous pests of turf, such as nematode Radopholus similis. Isazofos is also effective in the control of rice gall midge .
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-
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- HY-D0994A
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4-MUP disodium; MUP disodium
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Phosphatase
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Others
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4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
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-
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- HY-105790
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Pipethanate
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Cholinesterase (ChE)
|
Cardiovascular Disease
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Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates .
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-
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- HY-B1093R
-
|
Parasite
Cholinesterase (ChE)
|
Infection
|
Fenchlorphos (Standard) is the analytical standard of Fenchlorphos. This product is intended for research and analytical applications. Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction .
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-
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- HY-105790A
-
|
Cholinesterase (ChE)
|
Cardiovascular Disease
|
Piperilate (Pipethanate) hydrochloride is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate hydrochloride also causes hypotension and rescues mice poisoned by the organophosphates .
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-
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- HY-W011108
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|
Cholinesterase (ChE)
|
Neurological Disease
|
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated .
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-
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- HY-132409S
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-
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- HY-B1542AR
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Benactyzine hydrochloride (Standard) is the analytical standard of Benactyzine hydrochloride. This product is intended for research and analytical applications. Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research .
|
-
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- HY-N0584
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6-Hydroxyhyoscyamine
|
mAChR
|
Neurological Disease
Cancer
|
Anisodamine (6-Hydroxyhyoscyamine), a belladonna alkaloid, is a non-subtype-selective muscarinic, and also a nicotinic cholinoceptor antagonist. Anisodamine employs in traditional Chinese medicine for many ailments, mainly to improve the microcirculation in states of shock, and also in organophosphate poisoning .
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-
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- HY-116857R
-
|
Fungal
|
Others
|
Ditalimfos (Standard) is the analytical standard of Ditalimfos. This product is intended for research and analytical applications. Ditalimfos is an organophosphate fungicide. Ditalimfos is mainly used in agriculture to control fungal diseases of crops. Ditalimfos can be used for fungal resistance studies and risk assessment of residues in the environment .
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-
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- HY-123120
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|
Others
|
Others
|
SA-152 is an organophosphorus inhibitor. SA-152 modulates the fibrinogen coagulation and TAME esterase activity of bovine α-thrombin .
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-
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- HY-B1120S
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Temefos-d12
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Parasite
|
Infection
|
Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
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- HY-B0815S
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|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
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- HY-141728
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BCIPP
|
Endogenous Metabolite
|
Metabolic Disease
|
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .
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-
-
- HY-P2233
-
|
Bacterial
Antibiotic
|
Infection
|
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM .
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-
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- HY-B1621A
-
DL-Cyclopentolate hydrochloride
|
mAChR
|
Neurological Disease
|
Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice .
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-
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- HY-B1621AR
-
|
mAChR
|
Neurological Disease
|
Cyclopentolate (hydrochloride) (Standard) is the analytical standard of Cyclopentolate (hydrochloride). This product is intended for research and analytical applications. Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice .
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-
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- HY-B1621
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DL-Cyclopentolate
|
mAChR
|
Neurological Disease
|
Cyclopentolate (DL-Cyclopentolate) is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate is an anti-muscarinic agent commonly used in the ophthalmologic practice .
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-
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- HY-100979
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HDMPPA
|
mAChR
|
Others
|
W-84 (dibromide) is a potent allosteric modulator of M2-cholinoceptors, which retards [ 3H]N-methylscopolamine dissociation. W-84 dibromide can stabilize cholinergic antagonist-receptor complexes. W-84 (dibromide) is a non-competitive muscarinic acetylcholine receptors antagonist with allosteric effects. W-84 (dibromide) protects over additively against an organophosphate-intoxication when applied in combination with atropine .
|
-
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- HY-W653929
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BCIPP-d12
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0994
-
4-MUP; MUP
|
Chromogenic Substrates
|
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
|
-
- HY-D0994A
-
4-MUP disodium; MUP disodium
|
Chromogenic Substrates
|
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2233
-
|
Bacterial
Antibiotic
|
Infection
|
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-114899S
-
|
Azamethiphos-d6 is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .
|
-
-
- HY-132409S
-
|
Monocrotophos-d6 is the deuterium labeled Monocrotophos. Monocrotophos. Monocrotophos is an organophosphate insecticide with broad application in crops. Monocrotophos inhibits the activity of the acetylcholine esterase (AChE) enzyme and affects the neurotransmission between neurons[1].
|
-
-
- HY-B1120S
-
|
Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
|
-
-
- HY-B0815S
-
|
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
|
-
-
- HY-W653929
-
|
Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .
|
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