Search Result
Results for "
carbamoyl
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-160610A
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Others
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Others
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Carbamoyl phosphate dilithium salt is an antisickling agent and plays a significant role in the urea cycle. Carbamoyl phosphate dilithium salt carbamylates the amino-terminal valine residues of hemoglobin S in erythrocytes, which interferes with the sickling phenomenon. Carbamoyl phosphate dilithium salt exhibits toxicity due to the lithium cation .
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- HY-128425A
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L-Ureidosuccinic acid
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Endogenous Metabolite
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Others
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N-Carbamoyl-L-aspartic acid is intermediate of pyrimidine (HY-Y0519) metabolism. N-Carbamoyl-L-aspartic acid can be used to measure enzyme activity of dihydroorotase (DHOse) .
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- HY-128425
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- HY-79680
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Amino Acid Derivatives
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Others
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(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative .
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- HY-W705503
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- HY-Z3637
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- HY-165695S
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Isotope-Labeled Compounds
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Others
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 15N2 is 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-146716S
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Isotope-Labeled Compounds
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Others
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N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine.
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- HY-165694S
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Isotope-Labeled Compounds
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Others
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-165704S
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Isotope-Labeled Compounds
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Others
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2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium) .
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- HY-140459
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PROTAC Linkers
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Cancer
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2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-149664
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DC-Chol
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Liposome
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Cancer
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3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
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- HY-136128
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Potassium Channel
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Cancer
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H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity .
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- HY-P5126
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
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Cancer
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DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
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- HY-P5126A
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
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Cancer
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DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
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- HY-49395A
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Biochemical Assay Reagents
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Others
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(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride is a biological molecule.
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- HY-P5362
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- HY-P5362A
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- HY-W009512S1
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N-[(2-chlorophenyl)carbamoyl]phenylalanine-d6
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Isotope-Labeled Compounds
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Others
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N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide-d6 (N-[(2-chlorophenyl)carbamoyl]phenylalanine-d6) is deuterium-labeled CVT-2738 (HY-W009512) .
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- HY-W009418S
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- HY-P10137
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JR11
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Somatostatin Receptor
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Cancer
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Satoreotide (JR11) is a SSTR2 antagonist. Satoreotide is usually conjugated with radiolabeled chelators used in neuroendocrine tumor imaing .
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- HY-P5128
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- HY-B0711
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N-Carbamyl-L-glutamic acid
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Others
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Cancer
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Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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- HY-125734
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Liposome
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Others
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DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
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- HY-113416AS
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Isotope-Labeled Compounds
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Others
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Dehydroepiandrosterone sulfate-d6 (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].
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- HY-W719560S
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Isotope-Labeled Compounds
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Others
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Flupyrsulfuron-methyl-d6 is deuterium labeled Methyl 2-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-6-(trifluoromethyl)nicotinate .
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- HY-145087A
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- HY-B0711R
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N-Carbamyl-L-glutamic acid (Standard)
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Others
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Cancer
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Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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- HY-145087
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- HY-P2331
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Antibiotic A 3802-IV-3; Gardimycin
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Antibiotic
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Infection
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Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
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- HY-W009418S1
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3-carbamoyl-1-methylpyridinium iodide-d4 iodide
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Isotope-Labeled Compounds
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Others
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1-Methylnicotinamide-d4 iodide is deuterated labeled 1-Methylnicotinamide.
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- HY-106720C
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(+)-YM 09538
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Adrenergic Receptor
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Others
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(+)-Amosulalol ((+)-YM 09538) is an α,β-blocker with pharmacokinetic and metabolic activities in mice. In mice, the plasma concentration of (+)-Amosulalol decreased in a biphasic manner after intravenous injection. The time to reach the maximum plasma concentration after oral administration was 0.25h, and then decreased. The systemic bioavailability was 38.7%, and it was mainly excreted through urine. Multiple metabolites were detected in urine, and a new metabolite amosulalol carbamoyl glucuronide was found in bile samples.
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- HY-106720B
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(-)-YM 09538
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Adrenergic Receptor
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Others
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(-)-Amosulalol ((-)-YM 09538) is an α,β-blocker with pharmacokinetic and metabolic activities in mice. In mice, the plasma concentration of (-)-Amosulalol decreased in a biphasic manner after intravenous injection. The time to reach the maximum plasma concentration after oral administration was 0.25h, and then decreased. The systemic bioavailability was 38.7%, and it was mainly excreted through urine. Multiple metabolites were detected in urine, and a new metabolite amosulalol carbamoyl glucuronide was found in bile samples.
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- HY-P1726A
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Melanocortin Receptor
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Cancer
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MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
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- HY-P1726
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- HY-P0041
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- HY-P0041A
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- HY-103027
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5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido-1,5-dideoxy-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-allofuranuronic acid
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Fungal
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Infection
Inflammation/Immunology
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Polyoxin B is a potent chitin synthase inhibitor (IC50=0.08 mM) and an effective antifungal agent .
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Cat. No. |
Product Name |
Type |
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- HY-149664
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DC-Chol
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Drug Delivery
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3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-79680
-
|
Amino Acid Derivatives
|
Others
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(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative .
|
-
- HY-P5126
-
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
|
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- HY-P5126A
-
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
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- HY-P5362
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- HY-P10137
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JR11
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Somatostatin Receptor
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Cancer
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Satoreotide (JR11) is a SSTR2 antagonist. Satoreotide is usually conjugated with radiolabeled chelators used in neuroendocrine tumor imaing .
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- HY-P5128
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- HY-P4756
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Peptides
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Others
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N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P5362A
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- HY-P2331
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Antibiotic A 3802-IV-3; Gardimycin
|
Antibiotic
|
Infection
|
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
|
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- HY-P10014
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- HY-P1726A
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Melanocortin Receptor
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Cancer
|
MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
|
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- HY-P0041
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- HY-P0041A
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Optimized version of product available:
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Chemical Structure |
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- HY-W009418S
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1-Methylnicotinamide- 13C,d3 (iodide) is the 13C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide[1].
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- HY-113416AS
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Dehydroepiandrosterone sulfate-d6 (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].
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- HY-W705503
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3-Carbamoyl-1-methylpyridin-1-ium-d3 (iodide) is deuterium-labeled 3-Carbamoyl-1-methylpyridin-1-ium .
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- HY-165695S
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 15N2 is 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-146716S
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N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine.
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- HY-165694S
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-165704S
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2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium) .
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- HY-W009512S1
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N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide-d6 (N-[(2-chlorophenyl)carbamoyl]phenylalanine-d6) is deuterium-labeled CVT-2738 (HY-W009512) .
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- HY-W719560S
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Flupyrsulfuron-methyl-d6 is deuterium labeled Methyl 2-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-6-(trifluoromethyl)nicotinate .
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- HY-W009418S1
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1-Methylnicotinamide-d4 iodide is deuterated labeled 1-Methylnicotinamide.
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Cat. No. |
Product Name |
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Classification |
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- HY-140459
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Azide
PROTAC Synthesis
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2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-149664
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DC-Chol
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Cholesterol
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3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
|
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- HY-125734
-
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Cationic Lipids
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DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
|
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